Conquering TB: How Genomic Information And Tools Can Lead To New Tuberculosis Therapies That Combat Drug Resistance

Tuberculosis kills nearly 2 million people annually, and kills more adults than malaria, AIDS, and all tropical diseases combined. TB is the cause of one in four avoidable deaths in the Third World…

Cut Your Salt Use and Cut Your Risk of Heart Disease

(HealthDay News) — Reducing the amount of salt in your diet can lower your risk of developing heart disease by 25 percent and the risk of dying from heart disease by 20 percent, researchers report.

“Dietary intake of sodium among Americans is excessively high,” said lead researcher Nancy Cook, an associate professor of medicine at Harvard Medical School. “Our study suggests that reducing the level of salt in the diet would lead to a reduced risk of cardiovascular disease.”

Sodium is known to affect blood pressure levels, particularly among people with high blood pressure, Cook said. “Among hypertensive individuals, lowering sodium is pretty well established to lower blood pressure,” she said. “Now it looks like reducing sodium also has an effect on cardiovascular disease.”

In the study, Cook’s group examined people from two trials completed in the 1990s that analyzed the effect of reduced salt consumption on blood pressure. All the participants in the trials had “high-normal” blood pressure — sometimes called “pre-hypertension” — and were at increased risk of developing heart disease. Read more…

Cardiofy Heart Care Supplement

Prolonged systemic circulation of chimeric oncolytic adenovirus Ad5/3-Cox2L-D24 in patients with metastatic and refractory solid tumors

Prolonged systemic circulation of chimeric oncolytic adenovirus Ad5/3-Cox2L-D24 in patients with metastatic and refractory solid tumors

Gene Therapy advance online publication, March 18, 2010. doi:10.1038/gt.2010.17

Authors: S Pesonen, P Nokisalmi, S Escutenaire, M Särkioja, M Raki, V Cerullo, L Kangasniemi, L Laasonen, C Ribacka, K Guse, E Haavisto, M Oksanen, M Rajecki, A Helminen, A Ristimäki, A Karioja-Kallio, E Karli, T Kantola, G Bauerschmitz, A Kanerva, T Joensuu
& A Hemminki (Source: Gene Therapy)

MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed – updated hourly from thousands of authoritative health and news sources.

Feline leukemia virus integrase and capsid packaging functions do not change the insertion profile of standard Moloney retroviral vectors

Authors: J-Y Métais, S Topp, R T Doty, B Borate, A-D Nguyen, T G Wolfsberg, J L Abkowitz
& C E Dunbar (Source: Gene Therapy)

Self-complementary AAV-mediated gene therapy restores cone function and prevents cone degeneration in two models of Rpe65 deficiency

Authors: J Pang, S E Boye, B Lei, S L Boye, D Everhart, R Ryals, Y Umino, B Rohrer, J Alexander, J Li, X Dai, Q Li, B Chang, R Barlow
& W W Hauswirth (Source: Gene Therapy)

Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy

Authors: I Y Chen, O Gheysens, S Ray, Q Wang, P Padmanabhan, R Paulmurugan, A M Loening, M Rodriguez-Porcel, J K Willmann, A Y Sheikh, C H Nielsen, G Hoyt, C H Contag, R C Robbins, S Biswal, J C Wu
& S S Gambhir (Source: Gene Therapy)

Retraction

Human Gene Therapy Mar 2010, Vol. 21, No. 3: 363-363. (Source: Human Gene Therapy)

Clinical Impact of Suicide Gene Therapy in Allogeneic Hematopoietic Stem Cell Transplantation

Human Gene Therapy Mar 2010, Vol. 21, No. 3: 241-250. (Source: Human Gene Therapy)

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Tests for Genes Don’t Predict Breast Cancer Better

Studying genes linked to breast cancer may someday lead to better treatments, but they do little to improve a doctor’s ability to predict who is likely to develop a tumor, researchers reported on Wednesday.Source: Reuters Health
Related MedlinePlus Pages: Breast Cancer, Genes and Gene Therapy (Source: MedlinePlus Health News)

The Wire

Human Gene Therapy Mar 2010, Vol. 21, No. 3: 238-240. (Source: Human Gene Therapy)

Palm sales slump in third quarter as its new phones struggle for attention; stock hammered

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Palm’s phone sales slump and stock dives
NEW YORK — Palm Inc. reported sales figures Thursday that showed it’s having a difficult time getting consumers to pay attention to its phones in a market dominated by iPhones and BlackBerrys. The company’s shares plunged in after-hours trading.
The company shipped 960,000 smart phones to stores and …. Source  : Palm sales slump in third quarter as its new phones struggle for attention; stock hammered.

Summary Box: Court records show YouTube founders views on copyright

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Summary Box: Records illuminate copyright dispute
THE REVELATIONS: YouTube co-founder Steve Chen once warned a fellow co-founder to stop posting pirated videos on their Web site. And Viacom Inc. wanted to buy YouTube before getting beat out by Google Inc.
NO MORE SECRETS: The confidential information had been kept under wraps, until now, in Viacom’s …. Source  : Summary Box: Court records show YouTube founders views on copyright.

FDA panel recommends Boston Scientific’s electronic heart device for less-severe heart disease

FDA panel backs implant for mild heart failure

COLLEGE PARK, Md. — Federal health advisers say an electronic heart implant should be approved for millions of new heart-disease patients who currently aren’t eligible for the device.
A Food and Drug Administration panel of cardiologists voted unanimously in favor of Boston Scientific’s heart-regulating device to treat mild heart …. Source  : Gaea News Network.

Palm sales slump in third quarter as its new phones struggle for attention

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Palm’s sales slump as its new phones struggle
NEW YORK — Palm Inc. on Thursday reported sales figures that showed it’s having a difficult time getting consumers to pay attention to its phones in a market dominated by iPhones and BlackBerrys.
The company shipped 960,000 smart phones to stores and distributors in the quarter that … Read this article on Gaea Times at : Palm sales slump in third quarter as its new phones struggle for attention.

PNC Bank: National City Bank debit accounts hacked, hit with fraud

Former National City Bank debit accounts hacked

CHARLOTTE, N.C. — PNC Financial Services Group Inc. said Thursday it is investigating a systemwide account breach that affects former National City Bank customers and their debit card accounts.
The affected accounts are restricted to the Cincinnati area, and current PNC Bank customers are not affected, PNC Financial spokesman Fred … Read more : PNC Bank: National City Bank debit accounts hacked, hit with fraud.

Correction: SurModics licensing story

Correction: SurModics licensing story
EDEN PRAIRIE, Minn. — In a story and headline March 17 about SurModics Inc., The Associated Press reported erroneously that the company licensed technology from ForSight Labs LLC. It is licensing technology to ForSight. The article also reported erroneously that the I-Vation drug delivery technology that is not included in the licensing …. Source article on Gaea Times at  : Correction: SurModics licensing story.

Family history buffs to descend on Salt Lake City in late April for 4 genealogy conferences

Salt Lake City hosts 4 genealogy meetings in April

SALT LAKE CITY — Thousands of family history buffs are expected to descend on Salt Lake City in April for a unique week of four conferences focused on genealogy research and technolgy.
Anchored by the 2010 National Genealogical Society’s Annual Conference, the events begin April 26 and continue …. Original source  : Family history buffs to descend on Salt Lake City in late April for 4 genealogy conferences.

Court records show YouTube founders views on copyright, reveal Viacom wanted to buy YouTube

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Court records illuminate Viacom-YouTube battle
SAN FRANCISCO — YouTube co-founder Steve Chen once warned fellow co-founder Jawed Karim to stop posting pirated videos on their Web site, according to court documents unsealed Thursday as part of a 3-year-old copyright lawsuit.
That bit of intrigue was among the confidential information that had been kept under wraps …. Original article on Gaea Times at  : Court records show YouTube founders views on copyright, reveal Viacom wanted to buy YouTube.

Jerome York, Apple director, auto industry reformer and Kerkorian adviser dies at age 71

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Apple director, ex-auto executive York dies
DETROIT — Jerome York, an Apple Inc. board member and a financial wizard credited with turning around Chrysler and IBM, died Thursday of a brain aneurysm. He was 71.
He died at POH Regional Medical Center in Pontiac, Mich., after being taken there on Tuesday night.
York, who … Read more >>.

Is Google Go Going to be the Next “C” Language?

Google launched an open-source experimental programming language GO. The language combines the performance and security benefits that we get by using a compiled language like C++ with the speed of a dynamic language like Python. Now a days, libraries are getting bigger due to lots of recent development. Internet, networking and multi-core … Original source on Gaea Times at : Is Google Go Going to be the Next “C” Language?.

Mentor Graphics completes deal for Valor

Mentor Graphics completes deal for Valor
WILSONVILLE, Ore. — Mentor Graphics Corp., a provider of electronic hardware and software design products and services, said it has completed its buyout of Valor Computerized Systems Ltd.

The company paid $32.5 million in cash and 5.6 million shares of Mentor stock, making the deal worth about $50 million.
Valor makes software …. Read the original article  : here.

Accountability and Umbilical Cord Blood Legislation: CIRM’s Positions

As expected, directors of the California stem cell agency moved last week to attempt to sidetrack legislation aimed at ensuring affordable access to taxpayer-funded stem cell therapies and to improve accountability and transparency at the $3 billion enterprise.

The real question is what horse will CIRM have to trade in order to send the bill off to interim study, which would, in effect, kill it

Early Glance: Biotechnology companies (AP via Yahoo! Finance)

NEW YORK (AP) — Shares of some top biotechnology companies are up at 10 a.m.: Amgen rose $.38 or .7 percent, to $58.69. Biogen Idec rose $.66 or 1.1 percent, to $59.86. Celgene rose $.36 or .6 percent, to $65.38. Gilead Sciences rose $.24 or .5 percent, to $47.66.

Vastly Expanded Versatility Of Optogenetics Brain-Research Technique

Recently, brain researchers have gained a powerful new way to troubleshoot neural circuits associated with depression, Parkinson’s disease and other conditions in small animals such as rats. They use an optogenetics technology, invented at Stanford University, that precisely turns select brain cells on or off with flashes of light. Although useful, the optogenetics tool set has been limited…

Stanford Study: What Makes You Unique? Not Genes So Much As Surrounding Sequences

The key to human individuality may lie not in our genes, but in the sequences that surround and control them, according to new research by scientists at the Stanford University School of Medicine and Yale University…