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Category Archives: Biochemistry
Global Biochemistry Analyzer Market Growth to Thrive with Technology Advancement by 2025 Dagoretti News – Dagoretti News
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Newswise Nebraska food scientists are at the forefront in some of the hottest food and nutrition issues in the country the microbiome, which some predict to be one of the top nutrition issues in 2020; obesity, which continues to be a major health issue for the nation; food allergens, with the CDC reporting rising prevalence of food alelrgies in children; and food choice behavior.
On Jan. 29, a dozen researchers and scientists will be at the Food Innovation Center (1901 N. 21stSt., Lincoln, Nebraska) at Nebraska Innovation Campus to discuss their groundbreaking work with the media. The event begins at 11 a.m. with a brief overview of each research program. After a provided box lunch, media in attendance will have six 15-minute sessions to interview researchers. At 2 p.m., optional laboratory tours will be available for photos and b-roll. The event will be live-streamed for media who cannot attend in person.
Nebraska Food for Health Center,Andy Benson, director, professor of food science and technology; Amanda Ramer-Tait, associate professor of food science and technology; and Robert Hutkins, Khem Shahani Professor of Food Science and Technology. The center is located in the Food Innovation Center, 1901 N. 21stSt., on the Nebraska Innovation Campus of the University of Nebraska-Lincoln.https://foodforhealth.unl.edu
Nebraska Center for Prevention of Obesity Diseases,Janos Zempleni, director, Cather Professor of Nutrition and Health Sciences; Jiujiu Yu, assistant professor of nutrition and health sciences; Xinghui Sun, assistant professor of biochemistry; Yongjun Wang, research assistant professor of nutrition and health sciences; Edward Harris, associate professor of biochemistry; Alice Ngu, graduate research assistant in nutrition and health sciences. The center is located at 316C Leverton Hall, 1700 N. 35thSt., on the University of Nebraska-Lincoln East Campus.https://cehs.unl.edu/npod
Food Allergy Research and Resource Program,Joseph Baumert, director, associate professor of food science and technology; Melanie Downs, assistant professor of food science and technology; Philip Johnson, assistant professor of food science and technology; and Richard E. Rick Goodman, research professor of food science and technology. The program is located in the Food Innovation Center, 1901 N. 21stSt. on the Nebraska Innovation Campus of the University of Nebraska-Lincoln.https://farrp.unl.edu
Food Choice Economics,Christopher Gustafson, associate professor of agricultural economics, 314A Filley Hall, 1625 Arbor Drive on the University of Nebraska-Lincoln East Campus.
The Food for Health Center, a $40.3 million collaboration among academics, food and drug manufacturers and philanthropists, was established in 2017 to use microbiome research to link agriculture and food production to wellness and disease prevention.
Launched in 2014, the Nebraska Center for the Prevention of Obesity Diseases has received nearly $23 million from the National Institutes of Health to determine the molecular mechanisms that lead to obesity and to identify consumer friendly remedies.
For nearly 25 years, the Food Allergy Research and Resource Program has worked in partnership with the food industry to detect and eliminate allergens in the food supply.
Behavioral economist Christopher Gustafson is identifying the hidden factors that cause people to add an extra dollop of mayo to their sandwich or select an apple, not a brownie for a post-workout snack.
Please contact Leslie Reed at 402-472-2059 email@example.com reserve your space, including lunch, parking and optional lab tours.
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Top Diet and Nutrition Issues to be Highlighted during Jan. 29 Media-only Event - Newswise
This article was originally published on The Conversation, an independent and nonprofit source of news, analysis and commentary from academic experts. Disclosure information is available on the original site.
Author: Thomas Merritt, Professor and Canada Research Chair, Chemistry and Biochemistry, Laurentian University
You're reading this with a cup of coffee in your hand, aren't you? Coffee is the most popular drink in the world. Americans drink more coffee than soda, juice and tea combined.
How popular is coffee? When news first broke that Prince Harry and Meghan were considering Canada as their new home, Canadian coffee giant Tim Hortons offered free coffee for life as an extra enticement.
Given coffee's popularity, it's surprising how much confusion surrounds how this hot, dark, nectar of the gods affects our biology.
The main biologically active ingredients in coffee are caffeine (a stimulant) and a suite of antioxidants. What do we know about how caffeine and antioxidants affect our bodies? The fundamentals are pretty simple, but the devil is in the details and the speculation around how coffee could either help or harm us runs a bit wild.
The stimulant properties of caffeine mean that you can count on a cup of coffee to wake you up. In fact, coffee, or at least the caffeine it contains, is the most commonly used psychoactive drug in the world. It seems to work as a stimulant, at least in part, by blocking adenosine, which promotes sleep, from binding to its receptor.
Caffeine and adenosine have similar ring structures. Caffeine acts as a molecular mimic, filling and blocking the adenosine receptor, preventing the body's natural ability to be able a rest when it's tired.
This blocking is also the reason why too much coffee can leave you feeling jittery or sleepless. You can only postpone fatigue for so long before the body's regulatory systems begin to fail, leading to simple things like the jitters, but also more serious effects like anxiety or insomnia. Complications may be common; a possible link between coffee drinking and insomnia was identified more than 100 years ago.
Different people respond to caffeine differently. At least some of this variation is from having different forms of that adenosine receptor, the molecule that caffeine binds to and blocks. There are likely other sites of genetic variation as well.
There are individuals who don't process caffeine and to whom drinks like coffee could pose medical danger. Even away from those extremes, however, there is variation in how we respond to that cup of coffee. And, like much of biology, that variation is a function of environment, our past coffee consumption, genetics and, honestly, just random chance.
We may be interested in coffee because of the oh-so-joyous caffeine buzz, but that doesn't mean that caffeine is the most biologically interesting aspect of a good cup of coffee.
In one study using rats, caffeine triggered smooth muscle contraction, so it is possible that caffeine directly promotes bowel activity. Other studies, though, have shown that decaffeinated coffee can have as strong an effect on bowel activity as regular coffee, suggesting a more complex mechanism involving some of the other molecules in coffee.
What about the antioxidants in coffee and the buzz that surrounds them? Things actually start out pretty straightforward. Metabolic processes produce the energy necessary for life, but they also create waste, often in the form of oxidized molecules that can be harmful in themselves or in damaging other molecules.
Antioxidants are a broad group of molecules that can scrub up dangerous waste; all organisms produce antioxidants as part of their metabolic balance. It is unclear if supplementing our diet with additional antioxidants can augment these natural defences, but that hasn't stopped speculation.
Antioxidants have been linked to almost everything, including premature ejaculation.
Are any of the claims of positive effects substantiated? Surprisingly, the answer is again a resounding maybe.
Coffee won't cure cancer, but it may help to prevent it and possibly other diseases as well. Part of answering the question of coffee's connection to cancer lies in asking another: what is cancer? At its simplest, cancer is uncontrolled cell growth, which is fundamentally about regulating when genes are, or are not, actively expressed.
My research group studies gene regulation and I can tell you that even a good cup of coffee, or boost of caffeine, won't cause genes that are turned off or on at the wrong time to suddenly start playing by the rules.
The antioxidants in coffee may actually have a cancer-fighting effect. Remember that antioxidants fight cellular damage. One type of damage that they may help reduce is mutations to DNA, and cancer is caused by mutations that lead to the misregulation of genes.
Studies have shown that consuming coffee fights cancer in rats. Other studies in humans have shown that coffee consumption is associated with lower rates of some cancers.
Interestingly, coffee consumption has also been linked to reduced rates of other diseases as well. Higher coffee consumption is linked to lower rates of Parkinson's disease and some other forms of dementia. Strikingly, at least one experimental study in mice and cell culture shows that protection is a function of a combination of caffeine and antioxidants in coffee.
Higher coffee consumption has also been linked to lower rates of Type 2 diabetes. Complexity, combined effects and variation between individuals seems to be the theme across all the diseases.
At the end of the day, where does all this leave us on the biology of coffee? Well, as I tell my students, it's complicated. But as most reading this already know, coffee will definitely wake you up in the morning.
This article is republished from The Conversation under a Creative Commons license. Disclosure information is available on the original site. Read the original article:
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The biology of coffee, the world's most popular drink - Times Colonist
Latest release from Stratagem Market Insightswith title Biochemical Reagent Market Research Report 2019-2027 (by Product Type, End-User / Application and Regions / Countries) provides an in-depth assessment of the Biochemical Reagent including key market trends, upcoming technologies, industry drivers, challenges, regulatory policies, key players company profiles and strategies. Global Biochemical Reagent Market study with 100+ market data Tables, Pie Chat, Graphs & Figures is now released BY SMI. The report presents a complete assessment of the Market covering future trends, current growth factors, attentive opinions, facts, and industry-validated market data forecast until 2027.
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*** For the global version, a list of below countries by region can be added as part of customization at minimum cost.North America (United States, Canada & Mexico)Asia-Pacific (Japan, China, India, Australia, etc)Europe (Germany, UK, France, etc)Central & South America (Brazil, Argentina, etc)Middle East & Africa (United Arab Emirates, Saudi Arabia, South Africa, etc)
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Furthermore, the years considered for the study are as follows:
Historical year 2014-2019Base year 2019Forecast period** 2020 to 2027 [** unless otherwise stated]
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Saeideh Baradaran, 1 Akbar Hajizadeh Moghaddam, 1 Sedigheh Khanjani Jelodar, 1 Nasroallah Moradi-kor 2
1Department of Biology, Faculty of Basic Sciences, University of Mazandaran, Babolsar, Iran; 2Research Center of Physiology, Semnan University of Medical Sciences, Semnan, Iran
Correspondence: Nasroallah Moradi-korResearch Center of Physiology, Semnan University of Medical Sciences, Damghan Road, P.O. Box 35195-163, Semnan, IranEmail firstname.lastname@example.orgAkbar Hajizadeh MoghaddamDepartment of Biology, Faculty of Basic Sciences, University of Mazandaran, P.O. Box 57416-13534, Babolsar, IranEmail email@example.com
Background and purpose: Natural compounds are used for prevention of inflammation. Curcumin has antioxidant and anti-inflammatory properties, and loading it into nano-phytosomes may improve its efficiency. The present study investigates the effects of curcumin and its nano-phytosome on behavioral and biochemical responses in carrageenan-induced inflammation in the mice model.Methods: The mice were divided into six groups and received oral administration of curcumin or its nano-phytosome at a dose of 15 mg/kg for seven days before the administration of carrageenan. Acute inflammation in the mice was induced by administration of carrageenan (1%) into the subplantar region of the left paw. Antioxidant activity and behavioral responses were then evaluated.Results: The results showed that the serum concentrations of antioxidant enzymes were significantly higher in the sal+sal group compared to the cara+sal group (P< 0.05). Using nanophytosome, separately and in combination with indomethacin, increased the levels of antioxidant enzymes compared to the cara+sal group (P< 0.05). Latency was significantly lower in the cara+sal group compared to the cara+sal group (P< 0.05), but it was considerably higher in other groups, especially in the cara+nano.ph.cur+indo group (P< 0.05).Conclusion: It can be stated that the nano-phytosome of curcumin could improve antioxidant and behavioral responses in inflamed mice.
Keywords: antioxidant activity, inflammation, mice model, nano-phytosome
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Postdoc Position, Department of Biology job with MASARYK UNIVERSITY | 193197 – Times Higher Education (THE)
POSTDOC POSITION in Characterization of factors involved in metabolism of stalled replication forks and their possible disease relevance
Department Department of BiologyFaculty of Medicine
Deadline 29 Feb 2020
Start date March/April 2020 or upon agreement but no later than by 30th November 2020
Masaryk University, Brno, Czech Republic invites excellent scientists to apply for POSTDOC POSITION in Characterization of factors involved in metabolism of stalled replication forks and their possible disease relevance
The integrity of DNA continually resists the presence of physical and chemical carcinogens in our environment. In addition to exogenous agents, DNA undergoes spontaneous decay, including replication errors, oxidative and other damages which arise from common metabolic processes. The repair of damaged DNA is vital for the maintenance of genome integrity, and as aresult, all organisms have evolved awide variety of DNA repair pathways that can restore DNA structure and its genetic information.
The main objective of our research is to decipher the intrinsic functions of homologous recombination (HR) which has adual role in the maintenance of genome stability. First, it promotes the faithful repair of DNA double-strand breaks (DSBs) belonging among of the most lethal forms of DNA damage. Moreover, HR is responsible for the creation of genetic variability during meiosis by directing the formation of reciprocal crossovers that result in random combinations of alleles and traits. Changes in the execution and regulation of recombination are linked to human infertility, miscarriage and genetic diseases, particularly cancer thus emphasizing the importance of better understanding the mechanism and regulation of this pathway.
To achieve our goals, we utilize awide range of different methods from biochemistry, molecular biology, genetics, structural biology, and biophysics that are well established in our lab. Since we believe that interdisciplinary approach is needed to fully understand the fundamental biological processes, we also collaborate with numerous specialists.
The successful candidate should:
Specific criteria can be filled, i.e.:
The application should include:
MU offers the opportunity to get:
Anticipated start date:The position is available from March/April 2020 or upon agreement but no later than by 30th November 2020.
The submission deadline is29th February 2020.
Please submit your application by e-mail firstname.lastname@example.org
Areview of applications will commence immediately after the deadline. Short-listed candidates will be invited for interview within one month of the deadline.
Further information about:
prof. MUDr. Martin Repko, Ph.D.dkan