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Category Archives: Biochemistry

Mibelle debuts new moss based ingredient to harmonize the skin’s moisture flow – Premium beauty

A few years after the launch of MossCellTec No.1, the Swiss-based supplier of cosmetic ingredient is launching MossCellTec Aloe[1], an unequaled aloe-moss extract sustainably obtained.

Derived from aloe-moss (Aloina aloides), a tiny dark green to reddish-brown moss measuring 2 to 5 mm in height and known as common aloe-moss, MossCellTec Aloe improves cell-to-cell communication via connexin channels, optimally evens the moisture distribution in the skin and reduces the volume and depth of wrinkles.

Due to the similarity in the appearance of the leaves, aloe-moss was named after the Aloe vera plant. This rare and tiny moss species has a high water retention capacity. Compared to seed plants, mosses do not have roots and water transport systems. Instead, they absorb water directly into their leaves. Mosses can trap excess water and nutrients from the soil and air.

In vivo tests have shown that MossCellTec Aloe can reduce signs of skin aging (skin elasticity, wrinkle volume and depth), improve skin hydration and improve moisture homogeneity.

MossCellTec Aloe is based on Mibelle Biochemistrys MossCellTec technology which allows for the sustainable large-scale production of the moss extract.

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Letter for the article A Review on the Mechanism Between Different Fac | PRBM – Dove Medical Press

Correspondence: Abdul Moiz Sahito; Govinda KhatriDow Medical College, Mission Road, New Labour Colony Nanakwara, Karachi, Sindh, PakistanEmail [emailprotected]; govindakha[emailprotected]

We read a review article entitled A Review on the Mechanism Between Different Factor and the Occurrence of Autism and ADHD Xi et al published in Psychology Research and Behavior Management.1 We appreciate the authors for this informative review article and would like to make some contributions.

In this review, the authors have specifically elaborated genetic aspects and pathogenic hypotheses of these two kinds of neurodevelopmental diseases in children, autism, and attention deficit hyperactivity disorder (ADHD) while analyzing the relationship between different environmental toxins and these two disorders.1

Although, each disorders individual genetic profile was described the review lacked a mention of the shared genetic overlap between the two disorders and the biochemical factors affecting it. We want to highlight those aspects by mentioning that in a recent study conducted by Ma et al SHANK2 has been shown to be a potential pleiotropic gene underlying the genetic overlap between ADHD and Autism.2 It has been suggested that SHANK genes may play a crucial role in memory and executive dysfunctions found in a wide range of neuropsychiatric disorders, including ADHD and Autism Spectrum Disorder (ASD).3 There are also some biochemical factors that seem to affect the genes that ADHD and autism share. Recent studies have shown that Zn2+ ions are able to modulate the Postsynaptic Density (PSD) scaffold of synapses via the autism-associated proteins SHANK2 and SHANK3.4 Zinc deficiency has also been associated with ADHD. In a study conducted by El-Bakry et al Zinc was found to be significantly deficient in patients with ADHD compared with healthy controls, so it was concluded that zinc deficiency might play a role in the etiopathogenesis of ADHD.5

The shared genetic overlap between ADHD and Autism and the biochemical factors that affect that overlap makes it imperative that a thorough study is conducted in this direction to reduce the ambiguity underlying these disorders and to figure out efficient ways to prevent them.

The authors report no conflicts of interest in this communication.

1. Xi T, Wu J. A review on the mechanism between different factors and the occurrence of autism and ADHD. Psychol Res Behav Manag. 2021;14:393. doi:10.2147/PRBM.S304450

2. Ma SL, Chen LH, Lee CC, et al. Genetic overlap between attention deficit/hyperactivity disorder and autism spectrum disorder in SHANK2 gene. Front Neurosci. 2021;15:481. doi:10.3389/fnins.2021.649588

3. Guilmatre A, Huguet G, Delorme R, Bourgeron T. The emerging role of SHANK genes in neuropsychiatric disorders. Dev Neurobiol. 2014;74(2):113122. doi:10.1002/dneu.22128

4. Jan HH, Chen IT, Tsai YY, Chang YC. Structural role of zinc ions bound to postsynaptic densities. J Neurochem. 2002;83(3):525534. doi:10.1046/j.1471-4159.2002.01093.x

5. El-Bakry A, El Safty AM, Abdou AA, Amin OR, Ayoub DR, Afifi DY. Zinc deficiency in children with attention-deficit hyperactivity disorder. Egypt J Psychiatr. 2019;40(2):95. doi:10.4103/ejpsy.ejpsy_11_19

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4-H Foundation awards record number of scholarships for 2021 – The Star Beacon

JEFFERSON The Ashtabula County 4-H Foundation has awarded college scholarships to 14 local youths.

Thats a record number for the foundation,said 4-H president Jim Butler.

Since 1997, the Ashtabula County 4-H Foundation has been raising funds through multiple fund-raising events with the purpose of supporting advanced education of 4-H members.High school seniors and returning college students whohave participated in 4-H for a minimum offive years are eligible to apply, regardless of college or career choice.

The cost of college doesnt go down after the first year and it makes a big difference to get any help you can, Butler said. Some of our recipients applied last year and didnt receive one, but got one this year. You just never know. Different year, different judges. Just keep trying.

The 2021 recipients will need to successfully complete the fall semester to receive their scholarship in January. The recipients are as follows:

Kate Brand, a 2019 graduate of Jefferson Area High School. Sheattends Miami University-Oxford. She is double majoring in biology and psychology, and co-majoring in neuroscience.

Tory Durkovic, a 2021 graduate of Jefferson Area High School. She plans to attend Youngstown State this fall to major in Integrated Mathematics Education.

Katie Eldred, a 2019 graduate of Edgewood High School, who is pursuing a degree in sports psychology at the Ohio State University.

Emily Falcone, a 2020 graduate of Conneaut High School. She is returning to the University of Findlay studying animal science and pre-veterinary medicine.

Megan Jacobs, a 2020 Jefferson Area High School graduate. She attends Thiel College studying biochemistry.

Cheyenne Kase, a 2019 graduate of Jefferson Area High School. She attends the Ohio State University pursuing a degree in animal bioscience.

Emily Millard, a 2021 graduate of Pymatuning Valley High School. She will be attending Kent State-Trumbull campus studying for a bachelor of science in nursing.

Lydia Randolph, a 2021 graduate of Edgewood High School. She will be attending Trine University majoring in chemical engineering and biochemistry.

Caroline Sabo, a 2021 graduate of Madison High School. She will be attending the University of Akron studying civil engineering.

Shelby Schwotzer, a 2019 graduate of Edgewood High School. She will be returning to Grove City College studying biology and secondary education.

Garhett Smith, a 2020 Jefferson Area High School graduate. He attends Malone University studying zoo and wildlife biology.

Allison Stokes, a 2021 graduate of Pymatuning Valley High School. She plans to attend Kent State University-Main Campus studying general studies.

Emily Taft, a 2020 Jefferson Area High School graduate. She attends the Ohio State University studying history and education.

Faith Blankenship, a 2021 graduate of Jefferson Area High School. She is the 2021 recipient of the J.J. Stitt Memorial Scholarship. This scholarship is funded by the annual Ride for J.J. event and awarded through the 4-H Foundation and the Stitt Family. Faith plans to attend Youngstown State University and majoring in special education.

The 4-H Foundation extends a huge congratulations to all of the 2021 scholarship recipients and wishes only success to all of our local youth, Butler said.

We are making critical coverage of the coronavirus available for free. Please consider subscribing so we can continue to bring you the latest news and information on this developing story.

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North Carolina State University: Biochemical Sensor Researcher Makes MIT Technology Review’s List Of Top Young Innovators – Patch.com

Amay J. Bandodkar, an assistant professor of electrical and computer engineering at North Carolina State University, has been named one of MIT Technology Review's "Innovators Under 35" for his work on developing wearable biochemical sensors.

"I am very excited that Tech Review is recognizing our work to move health technology into the future," says Bandodkar. "I owe it to my amazing team members and mentors."

The annual list, which Tech Review has issued since 1999, was created to highlight exceptionally talented young innovators from around the world in a variety of fields. Previous winners include Mark Zuckerberg, Larry Page, Sergey Brin and Vivian Chu.

Bandodkar works at the interface of electronics, materials science, and biology to create next-generation wearable sensors with biomedical applications such as disease monitoring.

"My ultimate goal would be to develop technology that allows us to assess a person's health status by merely scanning a reader just like the tricorder from Star Trek," Bandodkar says.

Bandodkar joined NC State in January 2021, and is part of the university's National Science Foundation-funded ASSIST Center. The ASSIST Center's mission is to create self-powered, wearable health monitoring technologies.

Learn more about this year's honorees on the MIT Technology Review website here and in the July/August issue, which went live online June 30.

Founded in 1899, MIT Technology Review is an independent media company whose insight, analysis, and interviews explain the newest technologies and their commercial, social, and political impacts. MIT Technology Review's mission is to bring about better-informed and more conscious decisions about technology through authoritative, influential, and trustworthy journalism.

-shipman-

This press release was produced by North Carolina State University. The views expressed here are the author's own.

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Student fury as universities plan to continue online teaching into 2022 – LBC

5 July 2021, 14:15 | Updated: 5 July 2021, 15:30

Students have told LBC they are "infuriated" at plans from some universities to continue teaching parts of their course online, even as Boris Johnson is set to announce plans for all social distancing rules to be removed.

Multiple universities including Kent, Sheffield and University College London have already made public that students should expect "blended learning" - with some lectures given online.

Hundreds of students have signed a petition at Kent University after they said group lectures would continue online next year with the aim of reverting to in-person "in early 2022".

Manchester University has gone further, announcing a permanent move to including online teaching in their courses, including for "explanatory material" that would previously have been given in lecture theatres.

But despite promises of more in-person teaching, after over a year of watching lectures from their bedrooms students have told LBC they are thoroughly opposed to the plans and have little trust in university management.

Biochemistry first-year student Caitlin Wright told LBC she has only had four hours of in-person teaching in her first year at Manchester University.

"Labs have been taught by YouTube tutorials and when people went in to do one they had no idea what to do and how to use the equipment," she recounted.

Caitlin described the decision by Manchester to move to permanently include online teaching as part of the courses as "absolutely shocking and not in the best interests of students".

"I understand why it was necessary for this year but past the pandemic I am not sure why it is necessary.

"Everyone learns so much better in person, where they can bounce ideas off each other and put their hands up to ask questions. Online it takes three to five business days to get an answer to your question."

Read more: Manchester students claim police are carrying out 'random' Covid-19 checks in halls

Similarly, first-year Politics student Chris Adair told LBC he is worried the "quality of teaching will be severely affected if the university use the pandemic as an excuse to move to online teaching".

While the university says using a hybrid approach will allow students more flexibility, Chris told LBC he did not understand this as "many lectures were already recorded" pre-pandemic.

Chris said he and other students are "very, very worried" that the university could again move back to fully-online teaching.

"Last year they promised there would be blended learning and they reneged on that in the fist few weeks. There is uncertainty and real distrust between students and management."

Read more: Manchester Uni students pull down lockdown fencing put up around halls

Nick Hillman, Director of the Higher Education Policy Institute, told LBC universities have been scarred by the chaos of last autumn and are adapting their plans accordingly.

"Students regard learning as a social endeavour and see part of the university experience as spending time in the presence of people from other countries, other parts of the UK and other backgrounds," he explained.

"But universities got it wrong last year, when they promised face-to-face learning would come back earlier than it was allowed to for most students, and they are desperate not to overpromise this year."

Unlike Manchester, the University of Sheffield have not said they will be moving to blended learning permanently, but will adapt their learning to include online teaching "should this be necessary".

Sheffield say their "expectation and current plan is to deliver as much face-to-face teaching as possible in 2021-22", but students are concerned that they have heard nothing concrete from the university so far.

"I have only had 45 minutes of actually being at university, one in-person seminar the entire year," Politics student Dan Walsh told LBC.

"I would be hoping for an approach that is blended but also returns teaching to what it is meant to be," they continued.

"My course is meant to have 10 weeks of teaching but the university is saying because it is online only five weeks is needed.

"We're getting half the teaching for 9,000. That's not fair, that's not just."

Ahead of Boris Johnson's announcement that all sectors of the economy will now be able to open up, Dan added: "What difference is it going to make if we don't have in-person teaching if everyone is going to the pubs and clubs. It's pretty futile."

Explained: What time is Boris Johnson's announcement and what will he say?

Responding to the student's concerns, a University of Manchester spokesperson told LBC: This is not online teaching, but aboutaugmenting in-person lectures, seminars, labs, Q&As and discussions, and workshops with high quality online materials for self-study.

"We have been speaking to students for some time about ways to increase flexibility and choice and we will continue to do so to help shape this activity to their needs and the needs of each discipline.

"Our commitment to blended and flexible learning is part of the university strategy.

A University of Sheffield spokesperson said they "are working hard to provide the best on-campus experience in a Covid-secure way, in line with government guidelines.

Our top priority is always the wellbeing of our university community. Our expectation and current plan is to deliver the great majority of teaching face-to-face in September, with some larger lectures being delivered online.

"However, we have proven expertise in providing blended learning over the past year and will be able to adapt our learning and teaching delivery in response to new Covid-19 safety measures should this be needed.

"Digital delivery has opened up many possibilities for enhanced innovative learning and virtual social activities over the past year.

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The living pose greater covid19 risks than the dead – TT Newsday

CommentaryNewsday24 Hrs Ago

DR VISHNU BISRAM

CONVERSATIONS with Trinis suggest that last rites of covid19 deceased are not treated with respect and dignity. Families dont get to properly bid farewell because of rules. Public safety should never be compromised.

But common sensical applications should also not be ignored when treating the deceased who died of covid19. The deceased does not pose as much threat to public safety as the living. The probability of covid19 infection from the dead is minimal millions of times lower than getting covid19 from the living.

Families and communities can have proper and dignified burial or cremation rites for the covid19 deceased. The risks of attending a funeral for a covid19 victim is not any higher than that of attending a rite for someone who died from other causes or attending a religious institution for regular worshipping.

TT has countless biologists and biochemists who would have studied virology or virus contamination. I have not seen anyone address this issue of covid19 infection from a deceased.

I may be known as a pollster and social commentator, but I am also a degree holder in biochemistry and taught said subject as well as worked in biology labs for several years before making the transition to social science almost four decades ago.

My recollection from biology studies is a virus dies with its host, and thus the chance of the covid19 virus moving from the dead to the living, while possible, is very remote.

Tens of millions of people are hosts to covid19. The virus cannot reproduce without a living host. In theory, once the host dies, so does the virus. The covid19 virus survives for only a few hours (at most) without a host.

Of the millions of funerals of victims of covid19, only one person is known to have contracted the virus from the dead. Contrast this figure with the hundreds of millions who got infected by coming in contact with the living.

As long as proper safety measures are in place (safe distancing and wearing of PPE), normal funeral rites are safe (safer than going to a market or riding a maxi). In fact, in the US and other developed countries, almost normal funeral rites are being allowed.

When the virus broke out in January 2020 in the West, it was not clear how the virus spread. It was a mystery; scientists took a long time to understand its behaviour. In fact, it is still a mystery how it is mutating and combating the several vaccines.

Thus, the deceased was disposed of in closed bags, closed caskets (families could not see the face of loved ones), and closed rites from a far distance. But as scientists got an understanding of the viruss behaviour, coffins have been open over the last year.

Also, the dead is now ritually washed in America and properly dressed and displayed in full view. I attended funerals of several victims in New York; many Trinis and Guyanese who I knew died of covid19 in the US. I presided over the Hindu funeral rites of my mother who was a covid19 victim, including repeatedly touching her body as required by Hindu scriptures. Knowing the science, I had no reservations about touching her body.

I know of others who performed similar rituals for family members who died of covid19. None of them (or myself) contracted the virus from the deceased (and I did not even wear PPE when touching my moms body). Several individuals contracted covid19 from living family members who were covid19 positive (a few of who later died from the virus).

It is natural for people to be fearful of contracting the virus from the deceased covid19 victim. I too was very fearful and avoided funerals of covid19 deceased in the first several months of the pandemic. But it is now reassuring that the virus will not jump from dead to living.

No funeral worker (at a funeral home, crematorium, or graveyard) has been infected with the virus from handling the deceased. A lone case was that of an exposed pathologist (who did not wear PPP) who performed an autopsy of a covid19 victim some 15 months ago.

Once you wear PPE and maintain physical distancing, you will be safe. People should be more concerned about contracting covid19 from the living rather than the dead.

Thus, the Government should consider allowing normal funerals open coffins and cremations and attendance in public places. Families should be allowed to perform burials and cremations according to prescribed cultural and religious practices as the dead do not pose covid19 risk.

Attendees should take the necessary precautions to limit covid19 exposure from the living.

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