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Worlds oldest man, 112, shares the secret to longevity – Tampa Bay Times

Posted: February 15, 2020 at 11:47 pm

TOKYO A Japanese man with a sweet tooth who believes in smiles has become the worlds oldest male at 112 years and 344 days old, according to Guinness World Records.

Chitetsu Watanabe, who was born in Niigata in northern Japan in 1907, received a certificate for his accomplishment on Wednesday at a nursing home in the city.

The previous record holder, Masazo Nonaka, another Japanese, died last month. The oldest living person is also Japanese, Kane Tanaka, a 117-year-old woman.

Until about a decade ago, Watanabe used to do bonsai, the Japanese traditional art of raising small sculpted trees, and had his work exhibited.

These days, he loves desserts such as custards and cream puffs, Guinness said.

Watanabe graduated from agricultural school and then moved to Taiwan to work at Dai-Nippon Meiji Sugar on sugar cane plantation contracts.

He lived in Taiwan for 18 years. He married Mitsue and they had five children, Guinness said in a statement.

After the end of World War II, Watanabe returned to Niigata and worked for the prefectural government until retirement. He also grew fruit and vegetables on the family farm.

Asked about the secret to longevity, Watanabe has this advice: Dont get angry and keep smiling.

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Worlds oldest man, 112, shares the secret to longevity - Tampa Bay Times

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Michael Kors Broods on Longevity | Fashion Show Review, Ready-to-Wear Autumn 2020 | BoF – The Business of Fashion

Posted: February 15, 2020 at 11:47 pm

NEW YORK, United States Nancy Pelosi has always worn Michael Kors. She told him his clothes make her feel strong, and God knows thats something she needs in Washington. Before his show on Wednesday, Kors was talking about how its more important than ever to take a stand for your principles. If youre going to do battle, youd better feel confident doing it, he said. Thats the simple truth. If youre tugging at your dress, and youre crippled in your shoes, and you cant handle your bag Kors proudly pointed out there wasnt a stiletto heel or a skintight dress in his new collection. And we dont have a bag in the show thats not hands-free. Instead, his woman was dressed for the "real" world. We need a chic security blanket, thats the reality.

His business turns 40 next year, and he claimed hes been thinking about clothing in terms of a security blanket more or less the whole time. Kors has always been ready with a raft of references for each new collection usually a Hollywood style icon but with this major anniversary approaching, hes begun to reference his own work.

There sure is enough of it. Two decades ago, Naomi Campbell modelled a cape in a Kors show, Tina Barney later photographed writer Joan Didion wearing it. We got a phone call saying Joan wanted to buy the cape and I couldnt breathe, the designer recalled. Her writing, her sense of stylishness always knocked me out. Give me Mailbu Joan Didion and Im there. Kors owns Barneys photo. I wake up to it every day. That cape is graphic, it stands the test of time, Kaia Gerber is wearing it in the show today, 21 years later.

Remember in Citizen Kane how the sled called Rosebud was a childhood memory representing all that was simple, good and true for the business titan Charles Foster Kane as he lay dying? Not wanting to sound morbid or anything, but I wondered if the cape might be Korss Rosebud, the thread that runs through his lifes work. Hes a mad movie buff, so the idea appealed to him. He certainly gave us a show that was the cinematic apotheosis of the cape, in every possible guise: Victorian detective, highwayman, Zorro, poncho, blanket. Coats and capes combined, collars flared into capelets.

The simple, good and true bit worked because what Kors was after was a sense of the cosiness and comfort of country dressing given a bit of spit and polish for city life. Now more than ever, the simple truth is that our customers dream of being able to unplug and get out of town, but thats not the way life works out.

So Kors sold the fantasy the joy of wide-open spaces as efficiently as hes always plugged his glamorous Hollywood-spiked re-visions of Americana. The escapism, the honesty of the West is one of the things you can be proud of as an American, no matter what. There was a pony print trench, and a full-on riding look in amidst all the caped cosiness.

Classics. Longevity. Kors has been brooding on them. Funny thing is, we now have a whole new generation of customers who never thought about fashion as investment, but the sustainability conversation has woken them up. They say, I dont have to buy a dress to wear twice to post on Instagram, I can actually buy something thats beautifully made and hang onto it. Intelligently, thats what Ive always thought but now were seeing a whole new generation approaching that idea for a different reason. Thats amazing.

But, honestly, is it so amazing, when youre presented with something as effortlessly, common-sensically glamorous as a slinky grey cashmere turtleneck elongated over a fishtail skirt pav-ed with subtly gleaming graphite sequins and anchored by lug-soled boots? At what stage in the devolution of humankind is that not going to look good?

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Michael Kors Broods on Longevity | Fashion Show Review, Ready-to-Wear Autumn 2020 | BoF - The Business of Fashion

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NBA Rumors: Zion Williamson Longevity Comes First, Losing Weight Strongly Urged – International Business Times

Posted: February 15, 2020 at 11:47 pm


Zion Williamson is as good as advertised but his weight remains a critical issue. Being the third heaviest player behind Tacko Fall and Boban Marjanovic, there is no question that the top pick of the 2019 NBA Draft needs to shed off some weight if he wants to play pro ball continuously.

Currently at 284 pounds, Williamson is about the same weight as Nikola Jokic of the Denver Nuggets. Among the top five players in the NBA, he is the only one who is undersized and is not a center. Though most reason that Charles Barkley was able to survive with that frame during his prime, the NBA today is far different.

For now, all Williamson can do is heed the advice of the New Orleans Pelicans. He needs to think long-term and be made aware that longevity counts, ESPN reported. The good news is that the 19-year-old is listening, aware that all of this is for his own good. He sat out the game against their game against the Indiana Pacers but returned emphatically with a star-caliber performance against the Portland Trail Blazers, Yahoo Sports reported.

The minutes of Williamson for the Pelicans for the remainder of the season will be interesting. New Orleans currently sits at the 11th spot of the NBA Western Conference with a 23-31 win-loss card. With a string of wins, the Pels could catch the last bus to the NBA playoffs. However, they are likely to encounter rough sailing getting beyond the first round.

New Orleans could be tempted to field in Williamson and go beyond the managed minutes they have in place. But the risk behind that could be catastrophic, placing the former Duke Blue Devil's future at risk. Based on his showing against the Blazers, there is no denying that Williamson is a future star but adjustments are needed as far as his playing weight is concerned.

Williamson is likely to work on his weight problem by the summer. If he intends to play continuously and longer, he needs to burn some calories and reach the ideal playing weight for a 6-foot-6 individual. A look at shows that someone who stands at that height would ideally have a weight ranging from 193 to 235 lbs. Doing the math, this means Williamson will need to shed off about 50 pounds or more to be at his optimum best. This could also help address potential injuries such as his knees, something that kept him from playing the earlier part of the 2019-20 NBA season.

Zion Williamson seems bent on joining the Phoenix Suns next NBA season. Zion Williamson #1 of the Duke Blue Devils looks on against the Michigan State Spartans in the East Regional game of the 2019 NCAA Men's Basketball Tournament at Capital One Arena on March 31, 2019 in Washington, DC. Photo: Getty Images/Patrick Smith

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NBA Rumors: Zion Williamson Longevity Comes First, Losing Weight Strongly Urged - International Business Times

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How to live longer: Drinking this many cups of coffee can boost life longevity – Express

Posted: February 15, 2020 at 11:47 pm

When it comes to living a life disease-free, filled with energy and happiness and an impressive amount of time - everyone is intrigued. In fact, internet searches on the matter is astronomical with everyone wanting to know what is the secret. A certain hot beverage has been proven to add extra years to ones life and even reduce the risk of developing Alzheimers.

Drinking as little as two cups of coffee a day can increase life expectancy by a staggering two years, according to researchers.

The research, published in the European Journal of Epidemiology, was conducted by analysing previous studies on the health benefits of drinking coffee.

Looking at the 40 studies conducted including 3,852 651 subjects and 450,256 causes of death, researchers found that drinking coffee had an inverse association with all-cause mortality irrespective of age, weight, alcohol consumption, smoking status and caffeine content of coffee.


In recent years and decades, scientists have studied the effects of coffee on various aspects of health.

The research has shown that coffee doesnt just help to keep you awake - it can also make a person smarter.

Caffeine works in the brain by blocking the effects of an inhibitory neurotransmitter called adenosine.

By blocking the inhibitory effects of adenosine, caffeine actually increases neuronal firing in the brain and the release of other neurotransmitters like dopamine and norepinephrine, improving both mood and brain function.

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How to live longer: Drinking this many cups of coffee can boost life longevity - Express

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Are stem cells really the key to making humans live longer? –

Posted: February 15, 2020 at 11:47 pm

To some longevity acolytes, stem cells promise the secret to eternal youth. For a hefty fee, you can pay a startup to extract your own stem cells and cryogenically freeze them, in the hope that they can one day be used in a treatment to help extend your life.

Other firms let you bank stem cells from your babys umbilical cord and placenta after childbirth, if youre convinced the high cost represents an insurance policy against future illness. Or you can follow the example of Sandra Bullock and Cate Blanchett and opt for an anti-ageing cream made with stem cells derived from the severed foreskins of newborn babies in South Korea.

Stem cells are the parent cells which give rise to other cells in our bodies. Since scientists first isolated human embryonic stem cells in a lab and grew them over 20 years ago, they have been mooted as a source of great hope for regenerative medical treatments, including for age-related degenerative conditions such as Parkinsons, Alzheimers, heart disease and stroke.

But apart from a few small-scale examples, the only stem cell-based medical treatment practised in clinics uses haematopoietic stem cells found in the blood and bone marrow which only produce blood cells for transplants in blood cancer patients. These cells are taken from a patients sibling or an unrelated donor, before being infused into a patients blood, or theyre taken from a patients own blood before being reinfused. The procedure has been used to treat blood malignancies for almost half a century, and recently multiple sclerosis too. So how likely is it that the predictions about stem cells' longevity-enhancing powers will become a reality?

In September 2019, Google banned ads for unproven or experimental medical techniques such as most stem cell therapy, citing a rise in bad actors attempting to take advantage of individuals by offering untested, deceptive treatments [that can often] lead to dangerous health outcomes. The decision was welcomed by the International Society for Stem Cell Research, which emphasised that most stem cell interventions remain experimental. Selling treatments before well-regulated clinical trials have been done, the body said, [threatens public] confidence in biomedical research and undermines the development of legitimate new therapies.

Its easy to see how less scrupulous companies can exploit the allure of stem cells, which seem to occupy a place in our collective consciousness as a kind of magical elixir. High hopes for stem cell-based therapies have grown since 2006, when the Japanese biologist Shinya Yamanaka created a new technology to reprogram adult cells, such as skin cells, into a similar state to embryonic stem cells, which are pluripotent, meaning they can develop into any tissue in the body. The Nobel prize-winning breakthrough was hailed as a major step in the study of stem cells without the need for controversial embryo research, and towards the use of these human induced pluripotent stem cells to regenerate damaged or diseased organs or effectively grow new spare parts which could treat the life-limiting and life-shortening illnesses associated with ageing.

Gerontologist Aubrey de Grey, whose Strategies for Engineered Negligible Senescence (SENS) research foundation aims to eliminate ageing-related diseases, thinks the chances well soon have stem cell based therapies are high. For anything that's in clinical trials, you're talking about maybe five years before it's available to the general public, he says, citing stem cell treatments for Parkinsons disease, currently being tested in phase two clinical trials, as one of the developments he thinks is likely to come soonest.

However, given that these trials involve a relatively small number of participants and most clinical trials ultimately fail, his predictions might be overly optimistic. Often described as a maverick, De Grey believes that humans can live forever and there is a 50 per cent chance medical advances of which stem cell therapies will play an important part will make this a reality within the next 17 years. Though living forever, he says, is not the ultimate goal but a rather large side effect of medicine which will successfully prevent or repair the damage that comes with ageing.

For New Jersey-based Robert Hariri, who co-founded Human Longevity Inc, which set its sights more modestly on making 100 the new 60, stem cells derived from placentas present especially exciting opportunities. A biomedical scientist, surgeon and entrepreneur, Hariri says his current venture Celularity which is focused on engineering placental cells, including stem cells, to create drugs for cancer and other conditions is not as concerned about the actual age number, but about preserving human performance as we age and treating the degenerative diseases that rob us of our quality of life.

Many of those working in the field, however, remain cautious in their optimism. Researchers have highlighted the potential risks of giving pluripotent cells to patients, whether they are induced or embryonic, as these cells can develop cancer-causing mutations as they grow.

Davide Danovi, a scientist at Kings College Londons Centre for Stem Cells & Regenerative Medicine, says the path to stem cell-based therapy is very long and full of hurdles. The supply chain involves challenges, he says. On the one hand, allogeneic treatments those with stem cells derived from one individual and expanded into big batches to create cells to treat many individuals have the advantage of being similar to the traditional pharmaceutical business models. The product is clear, its something that comes in a vial and can be scaled up and mass produced, Danovi says. But this treatment can present a greater risk of rejection from the patient, as opposed to the more bespoke autologous option which is more expensive and time-consuming as it involves extracting a patients own stem cells before reprogramming them.

Danovi is most excited by the potential of stem cells to treat age-related macular degeneration. In 2017 Japanese scientist Masayo Takahash led a team that administered transplants of artificially grown retinal cells created from induced pluripotent stem cells taken from donors to five patients with the eye condition, which can cause blindness, and theyre reported to be doing well. The eye, he says seems to be a place where immunity plays less of a role relative to other issues, so you can host cells which come from another individual with fewer problems [of rejection]. But, with other organs such as the liver, he says there are major conceptual problems with creating enough tissue. Its like the clean meat burger - you're talking about a production that is, in many cases, not easy to reach with the current technology.

Hariri believes placentas will solve some of the production challenges crucially, theyre an abundant commodity, with the vast majority thrown out after childbirth. His interest was sparked 20 years ago when his oldest daughter was in the womb: When I saw her first ultrasound in the first trimester, the placenta had already developed into a relatively sizable organ, even though she was just a peanut-sized embryo. Id been taught that the placenta was nothing more than an interface, but [if that was the case], you would expect that it would grow at the same rate as the embryo. His curiosity piqued, he began to see the placenta not as an interface but as a biological factory, where stem cells could be expanded and differentiated to participate in the development of that foetus. That intrigued me and I started to collect placentas and just, you know, basically disassemble them.

Placentas have numerous benefits, he says they dont carry the same ethical controversy as embryonic stem cells, for one thing. Scientists working on embryonic stem cells have to destroy an early embryo, and that option yields them a dozen cells, which have to be culture-expanded in the laboratory into billions of cells. In contrast, the placenta houses, billions and hundreds of billions of cells, which can be expanded as well, but you're starting out with a dramatically larger starting material.

Increasingly, scientists in the anti-ageing sphere are focusing on an approach that seems like the opposite of planting fresh stem cells into our bodies. Experts such as Ilaria Bellantuono at Sheffield Universitys Healthy Lifespan Institute are working towards creating senolytics medication that could kill off our senescent cells, the zombie cells that accumulate in tissues as we age and cause chronic inflammation. I think stem cells are very good for specific disease, where the environment is still young, Bellantuono says, but the data in animal models tells us that senolytics are actually able to delay the onset and reduce the severity of multiple diseases at the same time for example, there is evidence for osteoarthritis, osteoporosis, cardiovascular disease, Alzheimer's, Parkinson's, and diabetes. She explains that while human trials are still in their early stages, senolytics are likely to be more cost-effective than stem cell therapy and the status quo of older patients taking multiple pills for multiple diseases, which can interact with each other. Besides, she adds, they may actually work in tandem with stem-cell based therapies in the future, with senolytics creating a more hospitable environment in tissues to allow stem cells to do their work.

And as for the so-called penis facial? Its far from the only ultra-expensive stem cell skincare making bold anti-ageing claims but youre probably better off saving your money, as you are with the experimental medical treatments on offer. Stem cells are definitely exciting but theyre not the key to eternal youth. At least, not yet.

Robert Harari will be one of the speakers at WIRED Health in London on March 25, 2020. For more details, and to book your ticket, click here

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Are stem cells really the key to making humans live longer? -

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Protect Yourself Against Cancer And Increase Life Expectancy By Eating The Best Diet – International Business Times

Posted: February 15, 2020 at 11:47 pm


Lifestyle is among the determinants of how long you may live. For those who regularly go on excessive alcohol drinking, consuming diets full of trans fats, and observe many other unhealthy practices, may not expect to live long.

Scientists and health experts have found long ago that to have a healthier and longer life, you should exercise regularly and consume a healthy and balanced diet. You should also limit your alcohol intake and quit smoking.

It is not at all surprising that observing a healthy diet can help a lot in improving longevity. With thousands of information as to what can be the best diet, however, you can easily get confused as to which one to follow.

Fortunately, recent research has shed light on what could possibly be the best diet that can help improve longevity and at the same time, help prevent cancer. live healthy life vegan diet increase longevity Photo: Rita E - Pixabay

Vegans May Have an Edge

Findings of a new study that were published in The Journal of Nutrition concluded that the secret to a long life might lie in veganism. Leading scientists and health experts agree, saying that a vegan diet helps in warding off a lot of diseases, including cancer.

Researchers revealed that based on the findings of their recently concluded study, the bodies of vegans contain the most antioxidants. According to health experts, this is primarily due to the high intake of vegetables and fruits.

It was also found out that those who follow a vegan diet have considerably lower death rates compared to meat-consumers. This new study reinforces findings of past researches that found a vegetarian diet, which consists mostly of nuts, wholegrain, legumes, fruits, and vegetables, lowers the risk of developing major ailments. It also helps you live longer.

The Vegan Research

Researchers from Loma Linda University have proven that men who follow vegan diets live an average of ten years longer compared to non-vegetarian men. Women following vegan diets, on the other hand, can add six more years of a healthy life, helping them reach an average age of 85 years.

Loma Linda University researchers also comprised the same research team that came up with the groundbreaking Adventist Health Study-1, a study that examines nutrition and life expectancy.This study was regarded as a benchmark in the nutrition world because of its comprehensiveness in terms of the number of participants and the length of time conducted.

Loma Linda researchers, for fourteen long years, tracked the diets, lifestyle, and ailments among 34,000 volunteers who do not drink or smoke. They found several habits that could add years to your life.

For one, the volunteers were consuming plant-based foods and were also consuming a handful of nuts regularly. They are also physically active and maintain a healthy weight. According to the researchers, these lifestyle habits could give you an extra two to three years of a fruitful life.

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Protect Yourself Against Cancer And Increase Life Expectancy By Eating The Best Diet - International Business Times

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