Category Archives: Resveratrol

According to a report published by TMR market, the Resveratrol economy is expected to witness a CAGR growth of XX% within the forecast period (2019-2029) and reach at a value of ~US$ at the ending of 2029. The macro-economic and micro elements which are predicted to influence the trajectory of this market are studied in the presented market study.

Light on the raw material throws Suppliers, vendors, manufacturers, and market consumers at the markets value chain. Furthermore, the political and economic scenarios of regions and its effect on the Resveratrol market are discussed within the accounts.

Critical Insights enclosed from this report:

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Competitive Outlook

Light onto the throws Business prospects of prominent players operating from the Resveratrol sector. The item pricing plans, marketing stations that were preferred , product portfolio of most players, and promote presence of each and every company is contained in the report. The dominant players covered in the report include Business, Business two, Business 3, and Company 4.

Regional Assessment

The presented market study sheds light on the Marketplace Scenario in various markets. Furthermore, the governmental and regulatory policies to the prospects of the Resveratrol market in each regions effect is analyzed in the report.

Market segments and sub-segments

The regional analysis covers:

The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industrys value chain.

A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.

Highlights of the report:

Note: Although care has been taken to maintain the highest levels of accuracy in TMRs reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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The report Suits the questions pertaining To the Resveratrol economy:

Reasons TMR Sticks out

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Resveratrol to Witness Growth Acceleration During 2018 2026 - Jewish Life News

Every week there are numerous scientific studies published. Heres a look at some of the more interesting ones.

Some Antibiotics Prescribed During Pregnancy Linked to Birth Defects

Researchers at the University College Londonfound that children of mothers prescribed macrolide antibiotics in the first trimester of pregnancy were at increased risk of major birth defects. The research was published in The BMJ. The birth defects include major malformations such as heart and genital defects, and four neurodevelopment disorders, cerebral palsy, epilepsy, ADHD, and autism spectrum disorder.

Macrolide antibiotics are used to treat a wide variety of bacterial infections and are among the most frequently prescribed antibiotics during pregnancy in Western countries, said Heng Fan, PhD candidate at UCL Great Ormond Street Institute of Child Health, and lead author of the study. This work builds on previous evidence of rare but serious adverse outcomes of macrolide use, especially for unborn babies. These adverse outcomes were assumed to be associated with the arrhythmic effect of macrolides, and policy advice about their use in pregnancy varies.

The investigators analyzed data from 104,605 children born in the UK from 1990 to 2016 from the Clinical Practice Research Datalink (CPRD), with a median follow-up of 5.8 years after birth. An additional 82,314 children whose mothers were given macrolides or penicillins before pregnancy and 53,735 who were siblings of children in the study acted as control cohorts. Major malformations were seen in 186 children of 8,632 whose mothers received macrolides at any point during pregnancy and 1,666 of 95,973 children whose mothers were dosed with penicillins during pregnancy. The researchers concluded that macrolides during the first three months of pregnancy were associated with an increased risk of any major malformation compared to penicillin.

The Mediterranean Diets Key Ingredient for Extending Lifespan

The Mediterranean diet has been noted for being heart-healthy and potentially improving lifespanheavy on fish, fruits, vegetables, grains, olive oil and red wine. Much research suggested the resveratrol found in red wine was the major contributor, but new research suggests it is actually the fat found in olive oil that activated a pathway known to increase lifespan and prevent aging-related diseases. It appears that the fat gets stored in lipid droplets and when the fat is broken down during exercise or fasting, the signaling and health benefits occur.

What Facebook and Genomes Have in Common

Computational biologists at Carnegie Mellon Universitytook an algorithm used to study social networks like Facebook and adapted it to identify how DNA and Proteins behave in communities inside the cell nucleus. Proximity is a factor, because genes controlled by the same regulatory proteins benefit from being close to each other, but others can be relatively far apart but drawn together via shared interests. The MOCHI algorithm analyzes the spatial arrangement of all the genes and transcription factor proteins in a nucleus based on genome-wide chromosome interactions and global gene regulatory networks.

A 3D Atomic Scale Map of the 2019 Coronavirus

Investigators at the University of Texas at Austin and the NIH created the first 3D atomic scale map of the 2019 novel coronavirus. They used AMETEK Gatans K3 camera to map part of the virus called the spike protein, which is how the virus penetrates the host cells. The breakthrough should allow for more rapid vaccine and therapy development.

How Lung Cancer Cells Suck Up Energy

Researchers working with human lung cancer cells discoveredhow they modulate their energy consumption based on their surroundings. In addition, they discovered how cancer cells override those factors to maximize their energy use. They identified a protein called TRIM21 that appears able to prevent the degradation of metabolic enzymes, resulting in cancer cells keeping their metabolism high. Being able to interrupt this pathway could lead to new approaches to cancer therapies.

New Hope for Muscular Dystrophy

Although there are now a couple therapies on the market for Duchenne muscular dystrophy (DND), it is still incurable. Researchers at the University of Pennsylvania School of Medicinerecently identified a group of small molecules that might lead to new treatments. The compounds eased repression of a specific gene, utrophin, in mouse muscle cells. This allows the body to produce more utrophin protein, which can be substituted for dystrophin, the protein whose absence causes DMD.

Were trying to find therapies that will restore a patients muscle function without resorting to gene therapy, said Tejvir S. Khurana, the studys senior author and professor of Physiology. Increasing utrophin is a major focus of muscular dystrophy research. While, ideally, we would replace the missing dystrophin in patients, there are a number of technical and immunological problems associated with this approach.

One is simply that the dystrophin gene is the largest in the body, and cant be fit into the viruses used for gene therapy. Most approaches along those lines use truncated dystrophin genes or other means to introduce a partial dystrophin gene or gene product. The other problem is that because the human body of DMD patients doesnt have regular amounts or types of dystrophin, introducing dystrophin to the body often stimulates an immune response as the immune system reacts to it as an invader.

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Research Roundup: Antibiotics Linked to Birth Defects and More - PharmaLive

Some women choose to give up alcohol and other substances in order to help with conception, but did you know that there are certain foods that increase fertility? While the idea of fertility foods might feel a little foreign, the way you nourish your body matters when youre trying to conceive. Many women dont realize that lifestyle, stress, and food can play a significant role in infertility, says Jayne Williams, a certified integrative health and nutrition expert. Eating a diet that supports fertility includes whole foods, a healthy balance of lean protein, healthy fats, and fiber that can help boost your gut microbe, regulate hormones, and lower stress levelsall three are important to prep your body for pregnancy.

When youre eating for reproductive health, foods that can help lower stress hormones and increase blood flow to the uterus are the ticket, says Lindsey Becker, a fertility chef, certified health coach, and founder of Farm Cut. From salmon and walnuts, which have been shown to reduce surges of stress hormones, to beetroots, which are rich in resveratrol and nitrates and are known to improve blood flow to the uterus to help with embryo implantation, she says, here are 13 foods that increase fertilityand how to eat them. Bon apptit!

You probably already love your guac, amirite? Turns out, avocados are a great fertility food. They are a fantastic source of vitamin E, which studies have shown can be beneficial in improving the lining of the uterus, says Becker.

Williams agrees. Avocados are one of my go-to favorites for healthy fat. They also happen to be high in potassium, folate, and vitamin K, which helps your body to properly absorb other vitamins.

One way to enjoy your avocado is to have avocado toast topped with pomegranate seeds for added antioxidants, Becker recommends. Another great treat is to simply add a quarter of an avocado to your daily smoothieit makes it creamier and adds a certain richness that will make your smoothie taste more like a milkshake. (Almost.) Plus, dont forget the guacamole, Williams says, which can be made simply with jalapeos, cilantro, and onion.

We should all be having dark green vegetables daily, but theyre especially important when youre trying to get pregnant. Kale, spinach, and Swiss chard contain essential prenatal nutrients like calcium, iron, and folate (which also helps protect against birth defects), not to mention tons of vital daily dietary fiber, says Williams.

There are endless ways to include your greens into your daily diet, Williams says. From eating them raw in salads, sauted, blanched, and steamed. Kale can also be roasted to make kale chips, while spinach can be added to smoothies since it has a very mild flavor. Just a small handful will do, she says.

Beets and their greens are an underestimated vegetable if I ever saw one. Beetroots are known to improve blood flow to the uterus to help with embryo implantation, explains Becker. Eating a diet rich in beets during IVF treatment is especially helpful. Thats why they should definitely be added to your fertility foods list, even if youre not going through IVF.

Theyre pretty simple to prepare too. All you need to do is treat them like potatoes: Wash and scrub them clean, and then toss them with olive oil, salt, and pepper. Wrap a whole one in tin foil and roast at 400 for about an hour, until tender, or shorten your time by chopping them into small pieces. Then, once theyre cooked, rub the skin off with your thumbs (wearing gloves because, otherwise, your hands will end up pink for hours) and toss with a little red wine vinegar and olive oil for a scrumptious salad. You can also add some sweet potatoes to this salad for an extra boost.

Read the rest here:
13 Foods that Increase Fertility - Glamour

A recent study investigated the associationbetween olive oil and decreased risk of aging-related diseases.

Olive oil is a primary source of fat in the Mediterranean diet. It consists of monosaturated fatty acids (MUFAs), the healthy fat that lowers cholesterol levels. It is rich in antioxidants, which help prevent cellular damage and decrease the risk of developing chronic diseases, such as cancer.

The Mediterranean diet is known for its wide range of health benefits, which include reducing overall mortality and aging-related diseases. Several studies suggest red wine as the main contributor in promoting the health benefits of the Mediterranean diet. This is because red wine contains resveratrol, a compound that activates SIRT1, a cellular pathway associated with extending lifespan and preventing aging-related diseases. However, in a recent study, researchers from the University of Minnesota identified olive oil as the key component in the Mediterranean diet that may contribute to lowering the risk of aging-related diseases and improve lifespan.

In the study, published in Molecular Cell, male mice, aged between six and eight weeks fed eithera diet that included olive oil, or a control diet that did not contain oliveoil, for twelve weeks. The control diet included soybean oil and lard. At theend of the feeding experiments, the mice were fasted for around sixteen hoursbefore their tissue and serum samples were collected.

The study reports that the fats in olive oil activated the SIRT1 pathway in the cells. These findings suggest that olive oil might play a key role in increasing lifespan and preventing aging-related diseases. According to the researchers, the consumption of olive oil by itself was not enough to gain its health benefits. The findings suggest that the effects of olive oil may be most noticeable when it is consumed in combination with fasting, exercising, and limiting caloric intake.

According to the study author, Dr. Mashek, the fat in olive oil is stored in lipid droplets, microscopic organelles in cells that provide storage for fats. Dr. Mashek suggests that when fat is broken down during fasting or exercising, the effects of the signalling in cells and the health benefits of olive oil are realized.

Future research will involve translating the findings tohumans with the aim of discovering new drugs or to tailor dietary regimens thatwill improve health outcomes in both the short-term and long-term.

Written byRanjani Sabarinathan, MSc

References:

Najt CP, Khan SA, Heden TD et al. (2020). Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1. Molecular Cell. doi: 10.1016/j.molcel.2019.12.003

University of Minnesota researchers discover Mediterranean diet ingredient may extend life. (2020, February 21). Retrieved from https://www.eurekalert.org/pub_releases/2020-02/uomm-uom022120.php

Image byPezibearfromPixabay

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Scientists shed light on the health benefits of olive oil - Medical News Bulletin

Heres the truth about serum: Its the biggest secret to having younger-looking, radiant skin.

You know all the other steps to staying healthyand showing it: wearing SPF, and applying retinol. You stay hydrated and eat healthy foods. You get lots of exercise and plenty of sleep. But, are you applying serums? They can give your skin some of the most immediate and impactful benefits.

Serum seeps into all three layers of your skin to work its magic at deeper levels than moisturizer ever could. Those moisturizing creams merely sit atop your skin. Theyre equally important, and shield skin from toxins, but they do little to reverse dark spots and smooth wrinkles. Serums, on the other hand, can correct hyperpigmentation and puffy eyes.

Serum brightens your skin complexion, and can preserve moisture levels in ways that moisturizers never could (funny, given its name). No two serums are alike in terms of ingredients and overall benefits, but almost all of them brighten your skin and smooth complexion. Here are seven of our favorite serums; apply them to clean, dried skin before moisturizers, SPFs, retinol or night creams.

If your skin suffers from redness or discoloration, then look for a corrective serum. SkinCeuticals gel serum uses thyme and cucumber extract to soothe irritation, as well as mulberry extract to even skin tone and gently hydrate the skin. If most moisturizers make your skin break out, then this is a gentle and top-notch moisturizing alternative.

Vitamin C is one of the best ingredients you can apply to skin for brighter, more even complexion. Glossiers serum is packed with it, along with magnesium, for an instant pick-me-up for tired or dull skin. Use it daily to preserve a fresh face, and to get ahead of the inevitable hangovers or early mornings.

The skin around your eyes is more sensitive than the rest of your face, and is much thinner, too hence why you quickly show signs of tiredness. (Its fluid buildup from a lack of rest, shining through your skin.) So, target the eyes with a special-blend serum that tightens and brightens at the same time. In OSEAs eye serum, hyaluronic acid preserves firmness and moisture levels, grape-seed-derived resveratrol shields this thin skin from toxins, and algae extract plumps and nourishes tired eyes (and alert eyes, if youre plenty rested already everyone benefits). It also prevents and helps reverse fine lines and other signs of aging.

Some serums are best worn during the day those that focus on hydration and pure brightening. Others, like corrective and exfoliating serums, are often best suited for bedtime so that they can sync with your bodys circadian rhythm to boost cellular turnover (and in turn guarantee that you wake up looking rested and more youthful). However, some serums cover both bases: Brickells night serum is ultra-hydrating so much so that its impact is maximized by wearing it overnight. Its loaded with plant stem cells, hyaluronic acid and vitamin C, and promises to magnify the benefits of a full nights sleep. Your friends and colleagues will notice the difference within days. (Assuming you arent pairing it with a lovely binge-drinking or chain-smoking habit.)

Theres an entire family of serums that focuses on exfoliation, by using ingredients that dissolve dead skin cells and reduce hyperpigmentation (dark spots and discoloration). Herbivores serum does so with alpha- and beta-hydroxy acids, all of which are naturally derived, despite their sciencey-sounding names. Theyre extracted from things like willow bark and sugar maple, and in turn leave skin bright, while minimizing pore size and smoothing skin texture.

Its hard to categorize Caudelies skin-brightening serum, since it uses the brands proprietary blend of ingredients (Viniferine, derived from grape vines) but they seem to deliver on their promise to brighten skin 62 times better than Vitamin C. All around the globe, this is what Caudelies spa customers pay top dollar for, and you can enjoy the same complexion-smoothing effects for less than a buck a day (assuming you just use a couple drops daily).

If your skin texture needs attention just as much as your skin tone, then look for a corrective and smoothing serum. This one from PCA Skin is pumped with peptides, and it waxes poetic on your skin to undo signs of aging (like the appearance of fine lines, wrinkles, dark spots and acne spots). It also helps skin retain moisture thanks to the inclusion of hyaluronic acid, rice bran extract, squalene, ensuring firmness and brightness.

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The Best Serums to Brighten and Refresh Dull, Tired Skin - gearpatrol.com

Happy National Drink Wine Day!

From dedicated Twitter and Facebook pages to people sharing their favorite varietal and vintage on social media, today is the day to raise a glass of wine.

A family toasts with wine in an undated stock photo.

Whether you're are looking to try a new bottle, better understand the health benefits or simply share a fun GIF, Feb. 18 is dedicated to spreading "the love" of wine.

Even celebrities like Kerry Washington, whose "Scandal" character Olivia Pope was known for her heavy pours, chimed in to celebrate the trending day.

"Wine Enthusiast" managing editor Lauren Buzzeo shared some expertise from choosing the right wine and understanding your palate to her personal favorite go-to bottle.

Wine is subjective and depends on personal tastes and experiences, but Buzzeo said for those new to wine, she would suggest starting with "fresh, fruit-forward selections with moderate acidity and low tannins, in the case of red wines."

"I generally start on the lower end of the tannic spectrum, because I find thats often what people have a hard time with initially," she explained of the bitter compounds that can leave an astringent feeling in the mouth. "Ill reach for a bright California Pinot Noir or Beaujolais, which is made from a grape called Gamay."

Wine bottles sit on a wine rack in an undated stock photo.

Buzzeo's advice is to start with what you like and fine tune based on your palate's preferences.

When it comes to white wine, Buzzeo said go for "a Spanish Albario or New World Sauvignon Blanc to start, and tune the choice from there. If youre looking for more weight, veer towards Chardonnay or Viognier."

One of the most common wine myths that Buzzeo helped dispel in honor of National Drink Wine Day is the broad generalization when people say, "I dont like Chardonnay."

"The grape is so versatile and easily influenced by both terroir and winemaker influence, that final wines from around the world run a huge spectrum," she explained. "If you think you dont like Chardonnay, instead pinpoint what about Chardonnay you dont like, because Im pretty sure theres a counterpoint to that bad experience you had and it might be amazingly delicious."

Once someone uncorks that wine they've carefully selected, the preservation game is on if you don't plan on finishing the bottle in one sitting.

Luckily, there are great gadgets on the market that Buzzeo said can help keep a bottle of wine fresh for days, weeks or even months.

"If youre constantly feeling like youre always looking for one glass and then letting the rest of the bottle go to waste before you get to enjoy more of it, invest in a Coravin," she said, "Its a fabulous system that will allow you to dispense pours from a sealed bottle for months without serious alteration to the wines profile."

She also suggested another innovative method, "trying out a wine club that specializes in single-serve pours; not only will you eliminate the possibility of any wine getting spoiled, but youll also get to try lots of different varieties from many regions to really discover a range of vinous possibilities."

Buzzeo said her go-to selection for National Drink Wine Day, would be an aged Barolo, in honor of her dad, "who introduced me to the wonderful world of wine and had a strong passion for Italian classics."

While the nationally recognized day can certainly seem "silly" at first, Buzzeo said simply, it helps raise awareness. "From Tacos to Tempranillo, who doesnt want an excuse to dive deeper and further appreciate something they either love or could stand to learn more about"

You don't need to be a sommelier to enjoy a glass of vino and various studies have shown that drinking red wine in moderation can be a healthy part of one's diet.

Dr. Melanie R. Graber, a resident with the ABC News Medical Unit, explained that people who choose to consume light to moderate amounts of alcohol may experience benefits in their health.

Red wine contains antioxidants called polyphenols, which, according to the Mayo Clinic, can "help protect the lining of blood vessels in your heart."

One polyphenol found in red wine, resveratrol, may help "prevent damage to blood vessels, reduce low-density lipoprotein (LDL) cholesterol (the "bad" cholesterol) and prevent blood clots," according to the Mayo Clinic.

A person pours red wine in an undated stock photo.

The USDA's 2015-2020 Dietary Guidelines for Americans defines moderate drinking as up to one drink per day for women and two drinks per day for men, with one drink listed as 8 to 20 grams of alcohol.

"Moderate alcohol consumption is thought to reduce risk of heart attack by increasing sensitivity to insulin, decreasing inflammation and decreasing blood clotting activity," Graber said.

While studies have been done into the benefits of red wine as it relates to reduced cardiovascular risk, the American Heart Association doesn't recommended that people who do not currently drink start drinking wine or alcohol for that sole purpose.

Various peer-reviewed medical literature on evidence-based medicine has shown that trials have had contradictory findings on coronary heart disease and it is unclear if wine is more cardio-protective than other alcohol types.

While there are some potential heart-healthy associations with drinking red wine and alcohol, drinking too much can increase the risk of liver and pancreas diseases, certain types of cancer, stroke, weight gain and other side effects.

So whether you reach for a biodynamic red from South America, chardonnay from Burgundy or a Napa Valley Cabernet, raise a glass today and enjoy responsibly.

More:
Cheers to these top vino for National Drink Wine Day - ABC News