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Category Archives: Longevity Medicine

NUS team’s map sheds light on heart diseases – The Straits Times

Researchers have developed a coherent map of genes in the heart and looked at how they may cause heart diseases, which could pave the way for new treatments for these illnesses.

Heart diseases are a complex set of diseases influenced by different genes, and it is challenging to understand which genes are responsible for a particular disease, say experts.

To help scientists unravel the complex web of genes and how they interact, researchers from the National University of Singapore Yong Loo Lin School of Medicine (NUS Medicine) and the National University Hospital created what they said is the first map of the heart's genes and the "switches" between them that control how the genes behave and contribute to heart diseases.

Genes code for specific traits, and the switches are the non-coding portions of DNA between the genes.

Each gene has more than one switch and the switches may be far away from the genes that they control, making it tricky for scientists to match the switches to the genes.

The genetic heart map locates the genes and their switches so that scientists can eventually study them to create targeted treatments, such as gene therapy.

"If we understand how these genes are controlled, then we may find ways to control heart failure itself... and identify new disease-causing genes," said Professor Roger Foo from the university's department of medicine, who led the research team.

Heart diseases, which eventually lead to heart failure, cause one-third of all deaths in Singapore annually.

The researchers are part of the Cardiovascular Disease Translational Research Programme, one of nine new strategic research focus areas that were established at NUS Medicine in July.

The new focus areas, which also include infectious diseases, healthy longevity and precision medicine, aim to create greater synergy and collaboration between basic and clinical scientists within the National University Health System, and to deliver research outcomes that address current clinical and national healthcare issues.

Professor Chng Wee Joo, vice-dean of research at NUS Medicine, said: "We hope that these nine programmes will deliver not just outstanding research, but over the next five to 10 years, make some real impact on how we treat our patients and on the population's health."

BETTER UNDERSTANDING

If we understand how these genes are controlled, then we may find ways to control heart failure itself... and identify new disease-causing genes.

PROFESSOR ROGER FOO, from the National University of Singapore's department of medicine, who led the team that developed the map of genes in the heart.

The development of the gene map was published as two companion publications in the journals Circulation Research and Circulation last month and this month respectively.

The map took about five years to develop, and the researchers studied tissues from 36 healthy hearts and 34 failing hearts to map out the genes and switches.

Prof Foo said some scientists from Singapore and abroad have reached out to them to find out more about various genes from the map.

He also noted that none of the drugs currently used in treating heart disease targets genes, and cardiovascular research is not as well funded compared with other health conditions.

"The place where a lot of gene targeting is happening, I feel, is in cancer. Looking at the progress that cancer treatment has seen in recent years with targeted therapy, this is our dream for cardiovascular disease also, now that we have mapped out all these specific processes," he added.

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The Benefits of CrossFit for People Age 60 and Above – BarBend

Its never too late to start.

Age is just a number.

These age old (no pun intended) adages are passed around a lot in the fitness community. Although often only meant as a means of inspiration, they may have a lot of truth to them as well, scientifically speaking. When it comes to improving physical and mental health, longevity, and quality of life, fitnessmight be one of the best means to do so. So we decided to do a deep dive on how and why CrossFit training can be a valuable fitness option for people over the age of 60.

Below are some of the major topics we cover:

In addition to better educating about how CrossFittraining can help build a stronger body, mind, and community, this article aims to be a go-to reference for common exercisesand how to get involved in competitive events.

Editors note: The content on BarBend is meant to be informative in nature, but it shouldnt take the place of advice and/or supervision from a medical professional. The opinions and articles on this site are not intended for use as diagnosis, prevention, and/or treatment of health problems. Speak with your physician if you have any concerns and before starting any new dietary or training regimen.

[Related: The ultimate guide to strength sports for Masters athletes]

Functional fitness is a classification of training that incorporates movements akin to what a person would perform in their day-to-day life. This can include squats, lunges, jumps, pulling movements, and cardio (running, biking, etc.). CrossFitmethodology adds in Olympic weightlifting (snatches and clean & jerks), powerlifting (deadlifts, front and back squats), explosive movements (using medicine balls, kettlebells, etc.), gymnastics, and some specialized movements such as rope climbs, sled work, and rowing.

There are many potential health benefits, so lets dive into what it can specifically offer athletes over the age of 60.

It is important to note the culture of support around the CrossFitcommunity. It is one of the most important means for acquiring new members as well as maintain those who have already been initiated. According to a 2018 systematic review and meta-analysis in theSports Medicine Open, preliminary data has suggested that CrossFit practice is associated with higher levels of sense of community, satisfaction, and motivation. (1)

It is likely the case that one of the biggest draws for anyone thinking of getting into CrossFittraining is improving longevity while maintaining or bettering physical capability. The evidence showing correlations between endurance training, high intensity interval training (HIIT), and high intensity functional training (HIFT) and longevity is pretty extensive.

Fifty-four peer-reviewed publications found considerable support for superior longevity for people involved in endurance related sport. (2) More specifically, a study in the Journal of Aging Research determined a physically active subjects had a higher life expectancy of upwards of 7 years.

A 2013 study in Population Health Managementrecognized that a critical need for senior-oriented programs that improve health and preserve and extend functional capabilities. The relationship between these improvements also led to reduced health care expenditures. (3)

For those who have not had a consistent training program, the intensity that comes along with CrossFit training might be intimidating. Dont worry, there are ways that new trainees can perform workouts without extending past their abilities or what is comfortable for them. One of the major ways is called scaling (more on this later).

Rest assured that the science is behind getting active to improve physical fitness even in the elderly. Progressive strength training in the elderly is an efficient wayto reduce sarcopenia and retain motor function, even at higher intensities, according to a 2011 study in theDeutsches Arzteblatt International.(4)

Furthermore, anyone who may be skeptical about the safety of higher intensity exercise, HIFT is not necessarily any riskier than any other form of exercise at a relatively equal intensity. A 4-year analysis that oversaw3,049 participants completed in 2018 in the Orthopedic Journal of Sports Medicinesuggested that CrossFit training is relatively safe compared with more traditional training modalities. (5)

Not only is getting physically active a smart choice for overall fitness levels, it might actually be better to train more days per week than less. That same 4-year analysis uncovered training for the majority of days per week could lead to fewer injuries. Those at the greatest risk of injury, primarily to their shoulders and back, were the participants who performed less than 3 workouts per week.

For athletes over the age of 60 participating in CrossFittraining for the first time, there should be some comfort knowing that the risk of injuryis similarto other sports according to a 2020 study in theJournal of Human Kinetics.(6) To further reduce the risk of injury, athletes are better off doing an adaptation period with the aim of improving technique. Good news:improving technique is a touchstone of CrossFit methodology.

Technique, which is defined in theCrossFitlevel 1 training guide as quality of movement, isan intimate part of safety, efficacy, and efficiency. Technique is everything. It is at the heart of our quantification. You will not express power in significant measure without technique.

So how does CrossFittraining adjust for those who have never done it before? They do so through scaling.

Scaling is the process of adjusting a workout or movement to better match the abilities of the person performing it. It is also a way to customize training for a persons needs at any given time. Feeling sore from a previous training session? Scale the workout. Feeling some tenderness in a muscle or joint and are concerned about aggravating it? Scale the workout.

Scaling is very important when learning a new lifting pattern. If someone has never performed a particular movement, it doesnt make much sense to load up a ton of weight and hope for the best. Remembering the importance of technique regardless of age or fitness level is key. CrossFit trainers are generally eager to work with clients to find the right movement patterns for their needs and goals.

As the trainee who will be performing the exercises, be sure to clearly articulate your goals. They can be as simple as wanting to walk up the stairs more efficiently or picking things off the ground without causing back pain. Scaling allows the trainer and the training itself to help further you toward whatever your goals may be.

Training in a group environment makes participants more motivated and more reliable the longer they do it. A 2019 study in thePLoS One(the Public Library of Science) looked into how motives differ by length of participation. They concluded that the enjoyment and challenge of HIFT was a sufficient motivator when beginning, and that this exercise form promotes an increase in those motives with greater length of participation.

The study also concluded that interpersonal motives (representing relatedness) also increase with participation time. (7) A 2017 study inBMJ Open Sport and Exercise Medicine furtherreinforces these ideas with their findings that group exercise helps participants meet recommended levels of physical activity. (8)

The community aspect of CrossFit enables a higher likelihood that people will exercise and enjoy it the more they do it. A2017 study inBMC Geriatrics concluded thatregular group exercise contributes to balanced health in older adultsand helped them to improve or maintain their functional health and enjoy their lives.(9)

There may be concerns for those above the age of 60 to get involved in any sort of group fitness. However, there are strong arguments to be made about ensuring exercise remains a part of the routine for seniors. In a 2018 study inFrontiers in Immunologythat analyzed exercise-induced immune suppression, scientists found thatleading a physically active lifestyle reduces the incidence of communicable (e.g., bacterial and viral infections) and non-communicable diseases (e.g., cancer), implying that immune competency is enhanced by regular exercise bouts.

They concluded that that leading an active lifestyle is likely to be beneficial, rather than detrimental, to immune function, which may have implications for health and disease in older age. (10)

Exercise has shown to aid other issues such as peripheral arterial diseaseand helpssuppress the most common age-associated chronic conditions.(11)In a 2015 study in Rejuvenation Research, scientists found that physical exercise islargely the answer to attenuate many of its deleterious systemic and cellular effects. (12)

Functional fitness training has potential benefits for physical and mental health, and longevity. But how and where does one sign up?

If youre interested in joining a CrossFit affiliate, youre in luck; as of early 2020, there are14,790 totalCrossFit affiliates globally.You can start by checking out theOfficial CrossFit Affiliate Mapthat can help locate the nearest CrossFit boxes near you.

When beginning, a coach will teach how to do the movements properly and adjust them as needed for your current fitness level (scaling!). CrossFit.com has quick tutorials that break down the movements so they can be practiced from home. There are also courses that anyone seeking to improve their health and fitness through effective training and nutritional strategies can take.

Here is a list of guides for the non-bodyweight movements you are likely to encounter that you can refer to:

Here is a list of guides for bodyweight movements:

If you are ever in a position where you dont have access to the requisite equipment, scale it and/or check out our CrossFitters guide to movement substitutions.

[Related: 8 things I wish Id known before starting CrossFit]

Whether youre just starting out in CrossFittraining or are actively looking to compete, being aware or even knowledgable about higher levels of competition cant hurt. It might even provide a means of inspiration. Here is a quick rundown of the pinnacle of CrossFit competition The CrossFit Games and how athletes get there.

It takes place once per year, is broadcast and live-streamed internationally, and features individual, team, and age group competition (teens and Masters divisions). There are four main ways to qualify for the CrossFit Games: Open, Sanctionals, Online Qualifiers, and Invitations.

The Open is a worldwide event that spans five weeks. Each week, a workout is released and participants are allotted four days to record their performance and submit it for review. Upon completion of the Open, the top ranked man and woman using a relative scoring system from each participating country is declared national champion(based on citizenship) and is offered an invite to the Games. In addition to the national champions, the top 20 men and women in the Open worldwide also receive invites.

Athletes results for each workout and their respective rankings are tracked via the CrossFit leaderboard. Leaderboards can be customized to highlight members of a group, profession, location, etc. so even if you dont have interest in higher competition, you can see how you stack up against a particular group.

According to CrossFits website,Sanctionals are independently owned and operated (and CrossFit-licensed) fitness competitions that offer another pathway for top men, women, and team athletes to receive invitations to compete at the CrossFit Games.

There were 28 Sanctionals planned around the globe that fed into the 2020 Reebok CrossFit Games. 26 teams (each comprised of 2 men and 2 women), 40 teens, and 120 Masters athletes are invited to the Games under the current format.

In competitive CrossFit, there are six Masters divisions that each span 4 years starting at age 35 up to the age 60+ division.Jarka GiangiulioandPatricia McGillare age 60 and 61, respectively, and are both CrossFit Games athletes.72-year-oldLaura Bruzzonedid not get started in the sport until age 67 and has some valuable advice to offer others who are considering doing the same.Below are their thoughts on CrossFit including their introductions to the sport and what motivates them to continue training.

Giangiulio achieved her firstmuscle-upat age 60 and is capable of deadlifting 285lb. She spent the first half of her life in Slovakia and has since been in the United States and trains atCrossFit Parallax in New Jersey. She placed seventh in the womens 60+ division in the CrossFit Games Age Group Online Qualifier to earn a spot at the 2020 Reebok CrossFit Games.

She started CrossFit in 2011 after getting her fitness in via aerobics, spin, and bootcamp classes. When asked what drives her to compete, Giangiulio responded:

theres this rush when you compete, and that feeling you get when you finish and you know you did well, its amazing. Its hard to explain. But its just good energy, and everyone is supporting you and cheering for you.

Another big draw to CrossFit is the efficiency of the training.

with CrossFit, theres always room for improvement, always something you can work on. I really like that. And I like that in just seven minutes, you can get a really hard workout and be done with it.

McGill began training CrossFit in 2013 and was the runner-up at the 2019 Reebok CrossFit Games in the 60+ division. She then followed it up with a 3rd place finish in theCrossFit Games Age Group Online Qualifier last fall. She trains six days a week and even performs workouts in her backyard.

I said to my husband, Honey, if I dig a hole, will you cement a pole so I can practice muscle-ups?

She splits her training between home workouts and sessions at the gym. Her basement is set up with kettlebells, dumbbells, a rowing machine, and the requisite Olympic weightlifting equipment. Her backyard is outfitted with a rope for climbs, a step for wall balls, and the aforementioned pole to support rings to allow for pull-ups and muscle-ups.

When asked what keeps her motivated to train into her 60s, McGill responded:

I just want to be able to continue to do whatever I want for the rest of my life.

The 72-year-old Bruzzone took up CrossFit five years ago after it was recommended to her by a friend. In her interview withGood Morning America, Bruzzone shared some advice for potential fellow Masters athletes:

You certainly shouldnt let age or anything else hold you back. So long as you dont give up and you do something, youre going to get payback, definitely.

Bruzzones training sessions and feats of strength in a CrossFit gym went viral as a means of inspiration for younger athletes. However, Bruzzone found the opposite to be true as she feels younger athletes inspire her:

I see the younger people doing heavier weights and I want to get closer to what theyre doing. Its more motivation for me to push harder.

Although Bruzzone has never competed in the CrossFit Open or at the Games, she still trains at 6am on most days, and only takes a rest day when she feels it necessary. Her fitness goals are positioned to thinklong term.

I have a long range plan. When Im 90, I want to get to the bathroom by myself.

We reached out to two doctors of physical therapy, Dr. Joseph LaVacca and Dr. Eugene Bo Babenko who is also a certified CrossFit trainer. They discussed the benefits and obstacles (both physical and mental), the remedies to those obstacles, personal experiences theyve had with their patients, and advice they would offer those starting out in functional fitness training.

Note: all bolding is done by BarBends editorial team for emphasis.

Functional fitness is the key here YES the way we think about aging is all sorts of messed up.If seniors, or any human of any age, want to be able to use their bodies, then they need to do some type of training to maintain it just like we do maintenance on our cars. While there is a natural degradation that comes with each day/month/year, it is all about managing that damage that allows us to improve healthspan, which implies the ability to be a more robust human for longer. If folks want to live longer and be able to do more things, then they 100% should participate in some kind of training program or movement practice.

Yes, without a doubt.Seniors biggest opportunity as they age is the loss of muscle mass, mainly power, and a narrowing social circle which is actually the number one factor for most of their stress and ailments. CrossFitis the perfect solution to both given classes are guided by coaches who understand the aging process and can be scaled accordingly to fit the capacity of each client.

More and more we are seeing research support the idea that we are not our x-rays or MRIs and a lot of the dysfunction we see with these images can sometimes be nothing more than normal age related changes our bodies go through as we continue to use them.

General de-conditioning is the number one overall ailment many of the cliches come to mind. Do we age because we stop dancing, or do we stop dancing because we get old? You are only as old as your joints feel.

The most common things that put folks in retirement homes or the morgue are a fall and broken hip the best way to combat this is to improve range of motion, proprioception, and strength. Leg strength, grip strength, and VO2 max are all incredible predictors of our mortality and can all be improved with functional training.

[CrossFit] also recently had a huge push for CrossFit Health, where they had seniors as the demo folks in a living room, using water bottles and such this is a great message and speaks to the fact that we all need to be partaking in some version of fitness for our entire lives and the barrier to entry should be very low.

As we age we are typically met with increasing co-morbidities such as weight gain, mental health issues, and changes to our cardiovascular systems (blood pressure/heart rate). I think community outreach and education can be an affective remedy.This population has survived and thrived through a lot of stress and changes in their lives. They very rarely want to be thought of as delicate, old or fragile. Holding 60+ classes to make people fit into a more common group of people, educating primary care physicianson the benefits of exercise as we age.

Aside from reduction in depression, anxiety and improved sleep, exercise has been shown to add years to your life, something that we can all likely agree is the ultimate benefit.

The biggest obstacle is fear/marketing it looks scary usually these CrossFit gyms have only young folks with shirts off huffing and puffing and making very loud noises of all sorts.

Culture seems to be the biggest obstacle for just about everything these days. When you are told that aging population is fragile, or should stop doing certain movements/exercises, or that their joints are bone on bone, those are the kind of thought viruses that spread very quickly,usually promoting fear and avoidance rather than reframing and lateralization.

Most effective remedies I have seen are specific silver sneakers programs specific marketing to get folks to see others in their age range can and are doingthis, and not getting injured. Sometimes its important to connect it to activities that are importantto that population.

I think community outreach and education can be an affective remedy. This population has survived and thrived through a lot of stress and changes in their lives. They very rarely want to be thought of as delicate, old or fragile. Holding 60+ classes to make people fit into a more common group of people, educating primary care physicianson the benefits of exercise as we age. Aside from reduction in depression, anxiety and improved sleep, exercise has been shown to add years to your life, something that we can all likely agree is the ultimate benefit.

Biggest benefits for CrossFit seem to be the increased ability to do the activities that we hold dear and overcome many of the aches and pains that we have built up over time. Another thing that works is one-on-one training with very personalized progressions.It is easier to throw constantly varied workouts at younger folks but as we develop more limitations we require more personalized attention to get better results and avoid injury.

These patients have more lean body mass, recover from injuries quicker, usually have jobs that they find more satisfying, are on little to no medications, and most important can envision their future and can continue to create goals both personally and professionally. One thing that happens as clients get older, retire, watch their kids grow is that they lose a sense of purpose. Those that maintain and active mind and body experience the same stressors but demonstrate more resilience when facing them.

Absolutely, I have worked with a number of folks above 60. Their performance far exceeds anyone in their cohort who does not. They are addressing so many physical factors.I also work as a home health physical therapist and I have seen everything from COVID pneumonia cases, stroke cases, etc., and no matter the age and function, I utilize many of the principles of CrossFit for my patients to help them improve and address their various impairments.

One thing that happens as clients get older, retire, and watch their kids grow is that they lose a sense of purpose. Those that maintain an active mind and body experience the same stressors but demonstrate more resilience when facing them.

Socialization hands down.The communities I have watched grow, and the friendships formed, allows for people to cheer for each other because they truly want what is in the best interest of the other person. CrossFit communities plan nights out, go to each others weddings, and even spend holidays together. As the gym grows, so does your family.

I would want to make sure they understand what the term CrossFit refers to. I would want them to be an educated consumer and ensure that thecoach/trainer they work with has some experience with similar pops and/or is able to provide them with a personalized plan to keep them safe and still reaping the benefits that the community setting brings.

That is great and I am proud of their decision. I would encourage them to look at their goals:

I would further suggest having a personal trainer that can work with their coach on your team. Where I think the biggest opportunity for community classes of all sorts to continue to evolve is providing information and understanding about each members individual capacity.

I think the concept is phenomenal. Ifell in love with it when I did my first workout and then did the CrossFit Level 1 certification. But since I entered the community in 2010, I have seen many versions of the original message create many watered down versions. It is going through some interesting changes withGlassmanselling the company. It will be interesting to see how it progresses.

In general I have been a huge fan and advocate for CrossFit since I began my career in 2010. Unfortunately the average career of a HIIT or CrossFit athlete (based on memberships) seems to be less than 3 years. This was presented at a Sports Symposium in Philadelphia not too long ago that I was able to attend.

This is the biggest opportunity for HIIT classes. Build consistency. The community is there, but people are scared and think this is not for me or I could never do that. Everyone is waiting to feel better to move or workout, rather than working out to feel better.

In addition, sometimes culture leads us to believe that we need to be emptying the tank all the time. That we need to be pouring sweat, not have an off day, or complete an insane challenge that we are not ready for to fit in. I would love to see more scaling to keep people safe, not just an RX and an alternative with less weight or reps something meaningful where this group can look at each other and say I am here and I am with other people just like me, and I do not have to be forced to do what is on the board.

I do believe that if every gym followed a CrossFit type model in a responsible manner, the world would be a healthier and stronger place.

The science is clear.CrossFittraining can enable people over the age of 60 the ability toimprove their physical fitness, their ability to day-to-day activities more efficiently, and their ability to prevent disease.It can offer a supportive community that can better ensure consistency in the gym and make workouts more enjoyable.

For those above 60 years of age looking to improve their futures, CrossFittrainings focus on individual goals and proper technique might be the way to go. There are CrossFitaffiliates are all over the world that can help you get a foothold in that community and build your body for many years to come.

Brent Hamar, et al. (2013). Impact of a Senior Fitness Program on Measures of Physical and Emotional Health and Functioning.Population Health Management.16(6): 364372.doi:10.1089/pop.2012.0111.

Allyson G. Box, et al. (2019). High Intensity Functional Training (HIFT) and competitions: How motives differ by length of participation.PLoS One.doi:10.1371/journal.pone.0213812.

Komatsu, H., Yagasaki, K., Saito, Y.et al.Regular group exercise contributes to balanced health in older adults in Japan: a qualitative study.BMC Geriatrics17,190 (2017). doi.org/10.1186/s12877-017-0584-3.

Tara L. Haas, et al. (2012). Exercise Training and Peripheral Arterial Disease.Comprehensive Physiology.2933-3017.doi:10.1002/cphy.c110065.

Feature image via Shutterstock/Halfpoint.

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Advanced Micronutrition Announces the Appointment of Faith Son as CEO to Lead the Healright Brand – Yahoo Finance

New Leadership To Position Healright As Leader In Food-As-Medicine Revival

Advanced Micronutrition today announced the appointment of Faith Son as Chief Executive Officer. Advanced Micronutrition is the maker of Healright, a groundbreaking, micronutrient-dense food solution that supports gut health and addresses serious health conditions. This is the first appointment of a CEO for Advanced Micronutrition and is a strategic move to establish its brand Healright as a leader in the food-as-medicine market and build Healright into a global wellness brand.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20200903005598/en/

Faith Son, CEO of Advanced Micronutrition and Healright. (Photo: Business Wire)

Faith Son, CEO of Advanced Micronutrition, said, "I am thrilled and honored to join Advanced Micronutrition as its first CEO. As a veteran of the food industry, a self-proclaimed foodie and longtime proponent of food as an intrinsic part of wellness, the opportunity to build Healright particularly during this time of especially acute appreciation of the health of our community -- is an exciting honor and privilege. I am looking forward to being a part of the journey to wellness for so many that need it."

Jonathan Smiga, Co-Founder of Advanced Micronutrition and Managing Partner of KEEN Growth Capital, said, "We are excited to appoint Faith Son as CEO because she has a track record for developing and growing innovative health & wellness food businesses on a global scale. She brings a unique combination of experiences that span classic CPG brand management roles across multiple food and beverage categories, vertically-integrated ingredient and product development expertise, and cutting-edge innovation strategy capabilities. Combined with tremendous entrepreneurial energy and strong people leadership skills, we are confident that she is the right person to lead Advanced Micronutrition and build Healright into a respected global wellness brand."

Faith joins the company with over two decades of experience in the food industry. She is the former Group Vice President, Head of Global Marketing and Innovation at PureCircle, the leading producer of stevia plant-based ingredients. In this role, she partnered with food industry players, ranging from the largest companies in the world to startups, to launch innovations and reformulations leveraging stevia as a plant-based alternative to sugar. Her leadership spanned marketing, consumer research, corporate communications, innovation pipeline, technical services, regulatory, and the Global Stevia Institute.

In addition, Faith had a diverse career at Kraft and Mondelez with a combination of general management, innovation and corporate roles. Her experiences ranged from Breakthrough Innovation Manager, launching Krafts only fresh produce product, to Category Director for Krafts $1B+ Enhancers business including Miracle Whip and Kraft Salad Dressing to Senior Director, Global Biscuit Category Team. She drove best-in-class growth of the $11B+ global biscuit portfolio through the creation of Mondelezs first-ever global innovation pipeline, focused on the fuel snacking market for global icon brands such as Belvita, Oreo and Club Social/Tuc.

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Faith joins the company from her role advising clients in the Food & Agriculture Practice Area at Clareo Partners, a leading innovation and growth strategy consulting firm, specializing in corporate entrepreneurship.

Faith has a B.A in Political Science from Stanford University and an MBA from the Kellogg School of Management at Northwestern University and. She lives in Chicago, IL suburbs with her husband and 2 daughters.

The Healright formula was developed by scientists at the USCF Childrens Hospital Oakland Research Institute (CHORI), in collaboration with the United States Department of Agriculture (USDA). It is backed by 15 years of research and development and 15 clinical studies.

About Healright & Advanced Micronutrition

Healright is wholly-owned by Advanced Micronutrition, which is a portfolio company of KEEN Growth Capital, an impact investing venture capital firm. Advanced Micronutrition believes that a life without the burden of disease is attainable, through science-backed foods that improve health and longevity. Healright Squares are an effective non-prescription, micronutrient-rich alternative that heals the human gut, thereby mitigating the causative effects of multiple diseases. Follow Healright in social media and sign up for more information or subscribe to a transformative health program at Healright.com.

About KEEN Growth Capital

KEEN Growth Capital invests in early stage food-related companies that generate meaningful social impact in addition to above market financial returns. KEEN has particular focus on healthy snacking, functional foods and patented, science backed companies that positively impact consumer health, environmental and community wellness, and long-term disease mitigation. Keens infusion of intellectual and financial capital delivers enriched outcomes for all stakeholders while creating a healthier world. KEEN is based in Orlando. Ideas welcome everywhere. Visit KEENGrowthCaptial.com for more.

Statements regarding Healright foods have not been evaluated by the FDA, and these foods are not intended to diagnose, treat, cure, or prevent any disease or condition. Customer results may vary and results may not always reflect the outcomes published in clinical studies on the Healright Formula. Healright is not a medical organization and our staff cannot give you medical advice or diagnosis and no content in any form on this website should be construed as medical advice or diagnosis.

View source version on businesswire.com: https://www.businesswire.com/news/home/20200903005598/en/

Contacts

Addison Ames VP, MarketingAddison@AdvancedMicronutrition.com 917.721.2961

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Building up its AI operations, GSK opens a $13M London hub with plans to woo talent now trekking to Silicon Valley – Endpoints News

Continuing its efforts to ramp up global AI operations, GlaxoSmithKline has opened a 10 million ($13 million-plus) research base in Kings Cross, London.

The AI hotspot is already home to Googles DeepMind, and the Francis Crick and Alan Turing research institutes. GSK said it hopes to tap into the huge London tech talent pool and attract candidates who might otherwise head to Silicon Valley.

Its a vibrant ecosystem that has everything from outstanding medicine as well as also being a big tech corridor. DeepMind is there. Google is there. Its near the Crick Institute, and of course modern computing was born, basically, with Alan Turing and the Turing Institute, GSK R&D president Hal Barron said at a London Tech Week fireside chat. So we are quite convinced that both the talent and the ecosystem will enable us to build a very vibrant hub in London, getting the top talent, the best thinkers and people to be able to interact with us in GSK to take technology and help us turn it into medicines.

The company believes AI has the power to vastly improve its drug discovery process. It claims that genetically validated drugs are twice as likely to be successful. And GSK has lots of genetic data to work with. The new workspace, located in the Stanley Building, has already lured in 30 scientists, 10 of whom are in the companys AI fellow program.

In fact, many biotechs are now turning to AI, which they believe can speed up successful development by analyzing hundreds of genes at once or rapidly screening billions of molecules.

GSK is focused on finding better medicines and vaccines not just better products, but finding them in better ways, so we are using functional genomics, human genetics and artificial intelligence and machine learning, the company said in a statement.

It also has AI researchers based in San Francisco and Boston, and aims to reach 100 AI-focused employees by mid-2021. Our goal is to have the best and brightest people in the world to join us, Barron said.

In AI, we are scouring the planet for the best people. These folks are very rare to find. Competition is high and there arent a large number of them, Tony Wood, GSKs SVP of medicinal science and technology, told The Guardian in December.

The new London hub has the capacity for 60 to 80 staff members. Now all thats left to do is fill it.

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For men, are two drinks really too much? – Lock Haven Express

A federal health panel now recommends that men consume no more than one alcoholic drink a day.

For 30 years, the Dietary Guidelines Advisory Committee set the limit at two drinks a day. (Women have long been urged to limit consumption to one drink a day.)

Other studies found that drinking under the previous two-beverage standard was actually good for the heart and that moderate drinkers live longer than abstainers.

So why was the earlier guideline chopped in half?

What we have here is a merger of several unfortunate habits in American policymaking where alcohol is concerned.

One is a long-standing disapproval of drinking. Prohibition was a moral crusade that ended in fiasco 87 years ago.

But theres a modern version that gussies up the disapproval as a health matter.

Most everyone agrees that continuous heavy drinking can devastate ones health and that addicts alcoholics should stop drinking altogether. But the new guidelines sloppily lump together excessive drinking with social drinking to make what was considered moderate consumption of alcohol look dangerous.

In response, five professors of medicine and epidemiology at Harvard sent a letter to federal officials expressing serious reservations about the new advisory.

It complained that the committee cited a paper showing that higher alcohol intake was associated with higher risk of all-cause mortality but ignored other data in the same study that the researchers say demonstrate a low-dose, high-frequency pattern was associated with significantly lower risk of total mortality.

In other words, the guidelines didnt distinguish between amounts being consumed.

As the signers put it, the original conclusion was biased by inclusion of binge drinkers who provide no evidence about the safety of within-guideline drinking.

The guidelines are updated every five years by the U.S. Departments of Agriculture and Health and Human Services. Three of the Harvard profs had previously served on the advisory committee.

This tightening of standards, The Washington Post notes, comes during a pandemic when alcohol consumption already at a 20-year high is spiking further.

That may be, but what does one have to do with the other?

We can well believe that some Americans have been drinking a lot more during the lockdowns.

If theres a problem, wouldnt it be the lot more rather than the two drinks versus one?

Thats like saying the way to stop drivers from speeding at 90 miles an hour is to lower the speed limit from 60 to 50.

BMJ, formerly the British Medical Journal, recently published a study that listed moderate alcohol intake among the five low-risk lifestyle factors associated with longevity. Interestingly, the United Kingdom in 2016 lowered its limit for low-risk drinking to 14 drinks a week for both men and women.

As for possible health benefits, researchers in Korea recently found a link between moderate drinking and lower levels of the protein that forms Alzheimers brain plaque, as reported in The New York Times.

They defined moderate drinking as up to 13 standard drinks a week.

Famous studies tie moderate wine consumption to lower rates of cardiovascular disease and longer lives.

Some of todays crusaders argue that it isnt the alcohol thats conferring the benefits.

Rather, wine drinkers tend to follow healthier lifestyles involving exercise, eating vegetables and social interaction.

But even if these doubters are correct that a wine-drinking culture only enabled the good health habits, whats wrong with that?

It is highly unlikely that those knocking down five glasses a night will pay the new guidelines any mind.

The bothersome part is that men who enjoyed a bourbon and a cabernet with dinner might feel pressured to cut their pleasure in half and for reasons little based on current science.

Froma Harrop is a Creators Syndicate writer.

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