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SK Life Science Announces Data Presentations for XCOPRI (cenobamate tablets) CV at the 2024 American Academy … – InvestorsObserver

PARAMUS, N.J. , April 9, 2024 /PRNewswire/ -- SK Life Science, Inc. , a U.S. pharmaceutical company in pursuit of developing treatments that will change the future of central nervous system (CNS) disorders, today announced the schedule for two oral and six poster presentations at the American Academy of Neurology (AAN) Annual Meeting taking place April 1318, 2024, virtually and in-person in Denver, Colorado . The data includes a study examining the relative bioavailability of cenobamate as an intact or crushed tablet administered either orally or via nasogastric tube, and a retrospective claims-based analysis comparing the effectiveness of cenobamate in reducing hospitalizations among patients with focal-onset seizures.

"We are looking forward to sharing data on the use and administration of XCOPRI in adults with partial-onset (focal) seizures at this year's AAN meeting," said Louis Ferrari , RPh, MBA, vice president, Medical Affairs. "At SK Life Science we are continually conducting research that will help healthcare professionals and equip them with the information they need to care for patients living with the challenges of epilepsy. We continue to do this via ongoing research, relevant post-hoc analyses, and the publication of real-world data on the use of cenobamate in the U.S. and globally."

Abstracts are available online on the AAN meeting website here and on site at booth #1262. The schedule of oral and poster presentations is detailed below.

Oral Presentations

Title: Comparative Effectiveness of Cenobamate in Reducing Hospitalizations in Patients with Focal-Onset Seizures: A Retrospective Claims-Based Analysis (Urban et al) Session: S29: Epilepsy Diagnostics and Therapeutics Date: Wednesday, April 17 Time: 1:24 PM

Title: Relative Bioavailability of Cenobamate 200 mg Administered as a Crushed Tablet, Either Orally or via Nasogastric Tube, vs an Intact 200-mg Cenobamate Tablet (Vashi et al) Session: S29: Epilepsy Diagnostics and Therapeutics Date: Wednesday, April 17 Time: 1:36 PM

Poster Presentations

Title: Effectiveness Of Cenobamate in Pediatric Patients with Lennox-Gastaut Syndrome: A Retrospective Claims-based Analysis (Keough et al) Session: P1: Epilepsy/Clinical Neurophysiology (EEG): Pediatric Epilepsy 1 Date: Sunday, April 14 Time: 8:00 9:00 AM

Title: Effectiveness Of Cenobamate in Pediatric Patients with Intractable Focal Seizures: A Retrospective Claims-based Analysis (Labiner et al) Session: P2: Epilepsy/Clinical Neurophysiology (EEG): Pediatric Epilepsy 2 Date: Sunday, April 14 Time: 11:45 AM 12:45 PM

Title: Increased Incidence of Comorbidities in Patients with Uncontrolled Epilepsy (Faught et al) Session: P4: Epilepsy/Clinical Neurophysiology (EEG): Epilepsy Co-morbidities and Special Populations Date: Monday, April 15 Time: 11:45 AM 12:45 PM

Title: Effectiveness Of Cenobamate in Postsurgical Patients: A Retrospective Claims-based Analysis (Pellinen et al) Session: P8: Epilepsy/Clinical Neurophysiology (EEG): Anti-seizure Medications: Clinical Trials and Outcomes Date: Tuesday: April 16 Time: 5:30 6:30 PM

Title: Cenobamate Use as Monotherapy: A Retrospective Claims-based Analysis (Becker et al) Session: P8: Epilepsy/Clinical Neurophysiology (EEG): Anti-seizure Medications: Clinical Trials and Outcomes Date: Tuesday, April 16 Time: 5:30 6:30 PM

Title: Dose Reduction Timing for Concomitant Antiseizure Medications: Post-hoc Analysis of a Phase 3, Open-label Study Of Cenobamate For Treatment Of Uncontrolled Focal Seizures (Ferrari et al) Session: P8: Epilepsy/Clinical Neurophysiology (EEG): Anti-seizure Medications: Clinical Trials and Outcomes Date: Tuesday, April 16 Time: 5:30 6:30 PM

AboutXCOPRI (cenobamatetablets) CV Cenobamateis an antiseizure medication (ASM) discovered and developed by SK Biopharmaceuticals and SK Life Science. While theprecise mechanism by whichcenobamateexerts its therapeutic effect is unknown, it is believed toreduce repetitive neuronal firing by inhibiting voltage-gated sodium currents. It is also a positive allosteric modulator of the -aminobutyric acid (GABA A ) ion channel.

Cenobamateis approved in the United States for the treatment ofpartial-onset seizures inadults andis available under the brand name XCOPRI (cenobamatetablets) CV.Cenobamatecan be combined with other ASMs or used alone.The recommended initial dosage ofcenobamateis 12.5 mg once-daily, with titration every two weeks; it is available in six tablet strengths for once-daily dosing: 12.5 mg, 25 mg, 50 mg, 100 mg, 150 mg and 200 mg.

Cenobamateis also approved in the European Union and the United Kingdomfor the adjunctive treatment of focal-onset (partial-onset) seizures with or without secondary generalization in adult patients with seizuresthathave not been adequately controlled despite a history of treatment with at least two anti-epileptic medicinalproductsand is marketed by Angelini Pharma under the brand nameONTOZRY .

Additionally,cenobamateis in clinical development in Asia . Ono Pharmaceutical and Ignis Therapeutics have the rights to develop and commercializecenobamatein Japan and in the Greater China region, respectively.SK Biopharmaceuticals has recently entered into an exclusive licensing agreement with Endo for cenobamate in Canada .

IMPORTANT SAFETY INFORMATION AND INDICATION FOR XCOPRI (cenobamate tablets) CV

DO NOT TAKE XCOPRI IF YOU:

XCOPRI CAN CAUSE SERIOUS SIDE EFFECTS, INCLUDING:

Allergic reactions: XCOPRI can cause serious skin rash or other serious allergic reactions which may affect organs and other parts of your body like the liver or blood cells. You may or may not have a rash with these types of reactions. Call your healthcare provider right away and go to the nearest emergency room if you have any of the following: swelling of your face, eyes, lips, or tongue, trouble swallowing or breathing, a skin rash, hives, fever, swollen glands, or sore throat that does not go away or comes and goes, painful sores in the mouth or around your eyes, yellowing of your skin or eyes, unusual bruising or bleeding, severe fatigue or weakness, severe muscle pain, frequent infections, or infections that do not go away. Take XCOPRI exactly as your healthcare provider tells you to take it. It is very important to increase your dose of XCOPRI slowly, as instructed by your healthcare provider.

QT shortening: XCOPRI may cause problems with the electrical system of the heart (QT shortening). Call your healthcare provider if you have symptoms of QT shortening including fast heartbeat (heart palpitations) that last a long time or fainting.

Suicidal behavior and ideation: Antiepileptic drugs, including XCOPRI, may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call your health care provider right away if you have any of the following symptoms, especially if they are new, worse, or worry you: thoughts about suicide or dying; attempting to commit suicide; new or worse depression, anxiety, or irritability; feeling agitated or restless; panic attacks; trouble sleeping (insomnia); acting aggressive; being angry or violent; acting on dangerous impulses; an extreme increase in activity and talking (mania); or other unusual changes in behavior or mood.

Nervous system problems: XCOPRI may cause problems that affect your nervous system. Symptoms of nervous system problems include: dizziness, trouble walking or with coordination, feeling sleepy and tired, trouble concentrating, remembering, and thinking clearly, and vision problems. Do not drive, operate heavy machinery, or do other dangerous activities until you know how XCOPRI affects you .

Do not drink alcohol or take other medicines that can make you sleepy or dizzy while taking XCOPRI without first talking to your healthcare provider.

DISCONTINUATION:

Do not stop taking XCOPRI without first talking to your healthcare provider. Stopping XCOPRI suddenly can cause serious problems. Stopping seizure medicine suddenly in a patient who has epilepsy can cause seizures that will not stop (status epilepticus).

DRUG INTERACTIONS:

XCOPRI may affect the way other medicines work, and other medicines may affect how XCOPRI works. Do not start or stop other medicines without talking to your healthcare provider. Tell healthcare providers about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

PREGNANCY AND LACTATION:

XCOPRI may cause your birth control medicine to be less effective. Talk to your health care provider about the best birth control method to use.

Talk to your health care provider if you are pregnant or plan to become pregnant. It is not known if XCOPRI will harm your unborn baby. Tell your healthcare provider right away if you become pregnant while taking XCOPRI. You and your healthcare provider will decide if you should take XCOPRI while you are pregnant. If you become pregnant while taking XCOPRI, talk to your healthcare provider about registering with the North American Antiepileptic Drug (NAAED) Pregnancy Registry. The purpose of this registry is to collect information about the safety of antiepileptic medicine during pregnancy. You can enroll in this registry by calling 1-888-233-2334 or go to http://www.aedpregnancyregistry.org .

Talk to your health care provider if you are breastfeeding or plan to breastfeed. It is not known if XCOPRI passes into breastmilk. Talk to your healthcare provider about the best way to feed your baby while taking XCOPRI.

COMMON SIDE EFFECTS:

The most common side effects in patients taking XCOPRI include dizziness, sleepiness, headache, double vision, and feeling tired.

These are not all the possible side effects of XCOPRI. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. For more information, ask your healthcare provider or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at http://www.fda.gov/medwatch .

DRUG ABUSE:

XCOPRI is a federally controlled substance (CV) because it can be abused or lead to dependence. Keep XCOPRI in a safe place to prevent misuse and abuse. Selling or giving away XCOPRI may harm others and is against the law.

INDICATION:

XCOPRI is a prescription medicine used to treat partial-onset seizures in adults 18 years of age and older. It is not known if XCOPRI is safe and effective in children under 18 years of age.

Please see additional patient information in the Medication Guide . This information does not take the place of talking with your healthcare provider about your condition or your treatment.

Please see full Prescribing Information .

About Epilepsy

Epilepsy is the fourth most common neurological disorder. Approximately 3.4 million people are living with epilepsy in the United States , with 150,000 new cases each year in the country. 1,2 Epilepsy is characterized by recurrent, unprovoked seizures. The seizures in epilepsy may be related to a brain injury or a family tendency, but often the cause is completely unknown. Having seizures and epilepsy can affect one's safety, relationships, work, driving, and much more. 3,4 People with epilepsy are at risk for accidents and other health complications, including falling, drowning, depression and sudden unexplained death in epilepsy (SUDEP). 3,4 Despite the availability of many antiepileptic therapies, almost 40 percent of people with epilepsy are not able to achieve seizure freedom, meaning they have epilepsy that remains uncontrolled. 5

About SK Biopharmaceuticals Co., Ltd. and SK Life Science, Inc.

SK Biopharmaceuticals and its U.S. subsidiary SK Life Science are pharmaceutical companies focused on the research, development, and commercialization of treatments for disorders of the central nervous system (CNS) and oncology. In 2017, SK Biopharmaceuticals established a research center to begin its expansion into oncology through research and development efforts. The companies have a pipeline of eight compounds in development in both CNS disorders and oncology. Additionally, SK Biopharmaceuticals is focused on the discovery of new treatments in oncology. For more information, visit SK Biopharmaceuticals' website at http://www.skbp.com/eng and SK Life Science's website at http://www.SKLifeScienceInc.com .

Both SK Biopharmaceuticals and SK Life Science are part of SK Group, one of the largest conglomerates in Korea. SK Inc., the parent company of SK Biopharmaceuticals, continues to enhance its portfolio value by executing long-term investments with a number of competitive subsidiaries in various business areas, including pharmaceuticals and life science, energy and chemicals, information and telecommunication, and semiconductors. In addition, SK Inc. is focused on reinforcing its growth foundations through profitable and practical management based on financial stability, while raising its enterprise value by investing in new future growth businesses.

References

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SOURCE SK Life Science, Inc.

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SK Life Science Announces Data Presentations for XCOPRI (cenobamate tablets) CV at the 2024 American Academy ... - InvestorsObserver

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Global Resveratrol Market is projected to reach US$ 278.3 Million by 2033 at a moderate CAGR of 8% | Get In-depth Report by Future Market Insights,…

Future Market Insights Global and Consulting Pvt. Ltd.

According to Future Market Insights, the North American region is forecast to lead the resveratrol market in 2023 and is likely do so throughout the forecast period. United States is a promising market in this region, which was estimated to have acquired 17.3% market share in 2022.

NEWARK, Del, May 09, 2023 (GLOBE NEWSWIRE) -- The estimated worth of the worldwide resveratrol market in 2022 was US$ 118.60 Million. Sales of dietary supplements is likely to increase to US$ 278.3 Million by 2033 thanks to shifting customer tastes, with a CAGR of 8% predicted for the forecast period of 2023 to 2033.

The growing demand for nutritional supplements among consumers is one of the main factors driving up the price of resveratrol on the international market. The market is expected to grow due to the product's high anti-antioxidant content and phenolic activities, which are popular with older consumers and sportsmen, as well as the increased prevalence of health issues including cardiovascular diseases. The increasing usage of nutraceuticals by the populace and the increasing reliance of the beauty sector on resveratrol all have an effect on the market's growth.

Download In-depth Report Sample @https://www.futuremarketinsights.com/reports/sample/rep-gb-2744

The use of this substance has been associated with a wide range of implications, including anti-angiogenic, estrogen-like effects, skin-whitening, anti-aging, collagen I activation, and its capacity to protect cells from oxidative damage and UV radiations-mediated cell death. It is well-liked in dermatology as well as cosmetology due to its ability to penetrate the skin barrier and its anti-aging properties.

Resveratrol has experienced extraordinary penetration in developed North American economies due to growing consumer demand for natural and healthy products. Consumers are turning to resveratrol supplementation for its antioxidant as well as anti-inflammatory qualities. Cardiovascular issues have increased in frequency in the United States as a result of the people's sedentary lifestyles, poor eating patterns, and hectic schedules. Resveratrol is a common ingredient in dietary supplements, which is anticipated to fuel the growth of the resveratrol market over the forecasted time period due to its multiple health benefits.

Story continues

Key Takeaways:

The global resveratrol market is expected to be valued at US$ 123 Million by 2023.

From 2018 to 2022, the market demand expanded at a CAGR of 3.1%.

In 2022, the United States market for resveratrol accounted for about 17.3% of the global market share.

The Indian resveratrol market to experience a rapid CAGR of 14% from 2023 to 2033.

By product type, the extract or plant-based resveratrol was estimated to acquire more than 40% share in 2022.

By Isomer, the trans-resveratrol had acquired a market share of 87%.

Resveratrol is gaining traction owing to its health benefits and having antioxidant, anti-inflammatory and anti-aging properties, says an analyst at FMI.

Competitive Landscape:

Prominent players in the resveratrol market are:

DSM Nutritionals

Evolva

Endurance Product Company

Great Forest Biomedical

Laurus Labs Limited

JF-NATURAL

Sabinsa Corporation

Resvitale LLC

Shanghai Natural Bio-engineering Co., Ltd.

Some key developments in this market are:

In 2021, Lonza, a worldwide manufacturing partner to the pharmaceutical, biotechnology, and nutrition sectors, declared it is likely to invest to build its production capabilities for pharmaceutical products at its facility in Guangzhou, China.

The fill as well as finish production line is likely to provide clinical trial and commercialization batches in China as well as local and international clients. In keeping with Lonza's objective to provide clients integrated end-to-end solutions, the launch of drug product manufacturing at the Guangzhou (CN) facility is likely to provide customers with a unified drug substance as well as drug product manufacturing service option.

More Valuable Insights Available:

Future Market Insights offers an unbiased analysis of the global resveratrol market, providing historical data for 2018 to 2022 and forecast statistics from 2023 to 2033.

To understand opportunities in the resveratrol market, the market is segmented on the basis of resveratrol by product (extract, fermentation, synthetic), form (powder and liquid), isomer (trans-resveratrol and cis-resveratrol), end-use and across five major regions (North America, Latin America, Europe, Asia Pacific and Middle East & Africa).

Get Your Queries Solved by Our Analyst @https://www.futuremarketinsights.com/ask-question/rep-gb-2744

Key Segments Profiled:

By Product:

Extract

Fermentation

Synthetic

By Form:

By Isomer:

Trans-Resveratrol

Cis-Resveratrol

By End Use:

Skin Care

Cream & Lotion

Scrub Exfoliator

Cleanser & Toner

Balm & Butter

Serum & Mask

Makeup Remover

Others

Hair Care

Shampoo

Conditioner

Essential Oil

Hair Color

Hair Stylist Products

Hair Oil

Makeup

Facial Makeup

Eye Makeup

Lip Makeup

Nail Makeup

Bath Care

Shower Products

Liquid Bath Products

Bath Additives

Bar Soaps

Fragrance

Tools

Dietary Supplements

Pharmaceuticals

Others

Table of Content (ToC):

1. Executive Summary | Resveratrol Market

1.1. Global Market Outlook

1.2. Demand-side Trends

1.3. Supply-side Trends

1.4. Technology Roadmap Analysis

1.5. Analysis and Recommendations

2. Market Overview

2.1. Market Coverage / Taxonomy

2.2. Market Definition / Scope / Limitations

3. Market Background

3.1. Market Dynamics

3.1.1. Drivers

3.1.2. Restraints

3.1.3. Opportunity

3.1.4. Trends

3.2. Scenario Forecast

3.2.1. Demand in Optimistic Scenario

3.2.2. Demand in Likely Scenario

3.2.3. Demand in Conservative Scenario

3.3. Opportunity Map Analysis

3.4. Product Life Cycle Analysis

3.5. Supply Chain Analysis

3.5.1. Supply Side Participants and their Roles

3.5.1.1. Producers

3.5.1.2. Mid-Level Participants (Traders/ Agents/ Brokers)

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Global Resveratrol Market is projected to reach US$ 278.3 Million by 2033 at a moderate CAGR of 8% | Get In-depth Report by Future Market Insights,...

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Quantum Could Solve Countless ProblemsAnd Create New Ones | Time

One of the secrets to building the worlds most powerful computer is probably perched by your bathroom sink.

At IBMs Thomas J. Watson Research Center in New York States Westchester County, scientists always keep a box of dental flossReach is the preferred brandclose by in case they need to tinker with their oil-drum-size quantum computers, the latest of which can complete certain tasks millions of times as fast as your laptop.

Inside the shimmering aluminum canister of IBMs System One, which sits shielded by the same kind of protective glass as the Mona Lisa, are three cylinders of diminishing circumference, rather like a set of Russian dolls. Together, these encase a chandelier of looping silver wires that cascade through chunky gold plates to a quantum chip in the base. To work properly, this chip requires super-cooling to 0.015 kelvinsa smidgen above absolute zero and colder than outer space. Most materials contract or grow brittle and snap under such intense chill. But ordinary dental floss, it turns out, maintains its integrity remarkably well if you need to secure wayward wires.

But only the unwaxed, unflavored kind, says Jay Gambetta, IBMs vice president of quantum. Otherwise, released vapors mess everything up.

Photograph by Thomas Prior for TIME

Buy a print of the Quantum cover here

Its a curiously homespun facet of a technology that is set to transform pretty much everything. Quantums unique ability to crunch stacks of data is already optimizing the routes of thousands of fuel tankers traversing the globe, helping decide which ICU patients require the most urgent care, and mimicking chemical processes at the atomic level to better design new materials. It also promises to supercharge artificial intelligence, with the power to better train algorithms that can finally turn driverless cars and drone taxis into a reality. Quantum AI simulations exhibit a degree of effectiveness and efficiency that is mind-boggling, U.S. National Cyber Director Chris Inglis tells TIME.

Read More: DeepMinds CEO Helped Take AI Mainstream. Now Hes Urging Caution

Quantums earliest adopters are asset-management firmsfor which incorporating quantum calculations involves few increased overhead costsbut commercial uses arent far behind. Spanish firm Multiverse Computing has run successful pilot projects with multinational clients like BASF and Bosch that show its quantum algorithms can double foreign-exchange trading profits and catch almost four times as many production-line defects. Quantum deep-learning algorithms are completely different from classical ones, says Multiverse CEO Enrique Lizaso Olmos. You can train them faster, try more strategies, and they are much better at getting the correlations that matter from a lot of data.

Quantum chandeliers may look spectacular but they arent practical for next generation computers. IBM has instead designed flexible cabling to replace the looped wires.

Thomas Prior for TIME

Data received from quantum computers must be fed to rack of classical control electronic systems to process the calculations.

Thomas Prior for TIME

Tech giants from Google to Amazon and Alibabanot to mention nation-states vying for technological supremacyare racing to dominate this space. The global quantum-computing industry is projected to grow from $412 million in 2020 to $8.6 billion in 2027, according to an International Data Corp. analysis.

Whereas traditional computers rely on binary bitsswitches either on or off, denoted as 1s and 0sto process information, the qubits that underpin quantum computing are tiny subatomic particles that can exist in some percentage of both states simultaneously, rather like a coin spinning in midair. This leap from dual to multivariate processing exponentially boosts computing power. Complex problems that currently take the most powerful supercomputer several years could potentially be solved in seconds. Future quantum computers could open hitherto unfathomable frontiers in mathematics and science, helping to solve existential challenges like climate change and food security. A flurry of recent breakthroughs and government investment means we now sit on the cusp of a quantum revolution. I believe we will do more in the next five years in quantum innovation than we did in the last 30, says Gambetta.

But any disrupter comes with risks, and quantum has become a national-security migraine. Its problem-solving capacity will soon render all existing cryptography obsolete, jeopardizing communications, financial transactions, and even military defenses. People describe quantum as a new space race, says Dan OShea, operations manager for Inside Quantum Technology, an industry publication. In October, U.S. President Joe Biden toured IBMs quantum data center in Poughkeepsie, N.Y., calling quantum vital to our economy and equally important to our national security. In this new era of great-power competition, China and the U.S. are particularly hell-bent on conquering the technology lest they lose vital ground. This technology is going to be the next industrial revolution, says Tony Uttley, president and COO for Quantinuum, a Colorado-based firm that offers commercial quantum applications. Its like the beginning of the internet, or the beginning of classical computing.

Quantum chips are extremely sensitive. This decade-old IBM quantum processor was used in an experiment that proved how background microwaves affect qubits.

Thomas Prior for TIME

If anything, its surprising that traditional computing has taken us so far. From the trail-blazing Apple II of the late 1970s to todays smartphones and supercomputers, all processors break down tasks into binary. But life is so complex that rendering information in such a rudimentary manner is like playing a Rachmaninoff concerto in Morse code.

Quantum is also more in tune with nature. Moleculesthe building blocks of the universeare multiple atoms bound together by electrons that exist as part of each. The way these electrons essentially occupy two states at once is what quantum particles replicate, presenting applications for natural and material sciences by predicting how drugs interact with the human body, or substances perform under corrosion. Traditional manufacturing takes calculated guesses to make breakthroughs through trial and error; by mirroring the natural world, quantum should allow advances to be purposefully designed.

Read More: Column: How Our Cells Strategize To Keep Us Alive

While the worlds biggest companies, alongside hundreds of startups, are clamoring to harness quantum, IBM has emerged in recent years as the industry leader. Today, the firm has over 60 functioning quantum computersmore than the rest of the world combinedand a roster of collaborators that include titans of practically every industry from Exxon-Mobil to Sony. Its a welcome return to technologys zenith for the storied firm, founded over a century ago to produce tabulating machines fed with punch cards. In recent years, IBM had fallen behind rivals like Apple and Microsoft by not seizing the initiative with cloud computing and AI. Quantum offers some redemption. Its great to be back at the top again, says one executive. Its no secret that we let things slip by not jumping on cloud.

In November, IBM unveiled its new 433-qubit Osprey chipthe worlds most powerful quantum processor, the speed of which, if represented in traditional bits, would far exceed the total number of atoms in the known universe. IBM has more than 20 quantum computers available on its open-source quantum tool kit Qiskit, which has been downloaded more than 450,000 times to date. In order to build an industry around quantum, some machines are free to use, while paying clients such as startups and scholars can access more powerful ones remotely on a lease basis. IBM has a bold road map to launch a 1,121-qubit processor this year and, by 2025, surpass 4,000 qubits by creating modular quantum circuits that link multiple processor chips in the same computer. Modularity is a big inflection point, says Dario Gil, IBM senior vice president and director of research. We now have a way to engineer machines that will have tens of thousands of qubits.

Inside the IBM research lab in Yorktown Heights, New York

Thomas Prior for TIME

IBM research lab in Yorktown Heights, New York.

Thomas Prior for TIME

Quantums industrial uses are boundless. Inside BMWs headquarters in Munich there stands a wall that gives vehicle designers sleepless nights. Creating a new car model from scratch takes at least four years. First, designers use computer-aided styling to sketch an exterior that combines beauty with practicality. Next, a scale model is carved in clay and placed in a wind tunnel to assess aerodynamics. After countless decisions on interior, engine performance, and so on comes the ultimate test: a prototype is driven at 35 m.p.h. into that fabled wall to test how it performs in a crash. Should the car fail to meet various safety criteria, its back to the drawing board.

This is where quantum can help by accurately predicting how complex materials of different shapes will perform under stress. Robust simulated crash tests can save up to six months in the whole process, says Carsten Sapia, vice president of strategy, governance, and IT security at BMW Group, which has partnered with French quantum firm Pasqal. Quantum computing will also help us find the new optimum between design, maximum interior space, and best aerodynamics.

Thats just the start. Modern business teems with optimization problems that are ideally suited to quantum algorithms and could save time, energy, and resources. Were not just building the technology, we have to enable the workforce to use it, explains Katie Pizzolato, IBMs director of quantum strategy and applications research.

Sapia says finding uses for the technology is easy; the challenge will be ensuring that all divisions of BMW are able to utilize it. Already, BMW is unable to communicate from Europe to its cars in China for driving software maintenance and monitoring because of increasingly strict curbs on the transfer of data across borders. In the future, we will rely on everywhere in the world having access to quantum technology to run our business, Sapia says. So how can we set it up so no matter what happens on a geopolitical scale that we still have access to this technology?

The full chandelier inside a quantum computer.

Thomas Prior for TIME

Over the past few years quantum has moved from a footnote to the top of the global security agenda. To date, 17 countries have national quantum strategies and four more are developing them. China has invested an estimated $25 billion in quantum research since the mid-1980s, according to Quantum Computing Report. Its top quantum scientist, Pan Jianwei, led the launch of the worlds first quantum satellite in 2016 and in 2021 unveiled a then record-breaking 56-qubit quantum computer. Chinas 14th Five-Year Plan, published in March 2021, made mastery of quantum a policy priority. The blurred line between industry and national security in China gives them an advantage, says David Spirk, former chief data officer at the Department of Defense.

In response, the White House in May published a National Security Memorandum that ordered all federal agencies to transition to post-quantum security owing to significant risks to economic and national security. Given that upgrading critical infrastructure can take decades, and literally everything connected to the internet is at risk, the impetus is to act now. We realized that while [quantum is] wonderful for humanity, the first thing people are going to do is weaponize these systems, says Skip Sanzeri, founder and COO of QuSecure, a post-quantum cybersecurity firm enlisted by the U.S. military and federal government to handle what he says could be a $1 trillion cybersecurity upgrade.

Still, Spirk worries that the U.S. risks falling behind and is calling for a Manhattan Projectlike focus on quantum. Of the over $30 billion spent globally on quantum last year, according to the World Economic Forum, China accounted for roughly half and the E.U. almost a quarter. The U.S. National Quantum Initiative, meanwhile, spent just $1.2 billiona figure Spirk calls trivial against $1 trillion in total defense spending. This is not a coming wave, he says, its here.

Read More: The World Economic Forums Klaus Schwab on What Lies Ahead

The stakes couldnt be higher. Today, practically all cybersecuritywhether WhatsApp messages, bank transfers, or digital handshakesis based on RSA, an asymmetric cryptography algorithm used to safely transfer data. But while a regular computer needs billions of years to crack RSA, a fast quantum computer would take just hours. In December, a team of scientists in China published a paper that claimed it had a quantum algorithm that could break RSA with a 372-qubit computer (though its conclusions are hotly debated). The race is now on to devise postquantum securitya job that falls to the U.S. National Institute of Standards and Technology, or NIST. In 2016, NIST announced a competition for programmers to propose new post-quantum encryption algorithms. The results were mixed: one of the finalists announced on July 5, 2022, has since been cracked by a regular laptop in a little over an hour.

In some ways, its already too late. Even though quantum computers powerful enough to crack RSA are a few years away from being openly available, hackers are already seizing and storing sensitive data in the knowledge that they will be able to access it via quantum very soon. Every day that you dont convert to a quantum-safe protocol, theres no recovery plan, Gil says.

The glass shell around the quantum computer allows IBM to tightly control the temperature inside. This is critical for the quantum chip, which has to be kept at a fraction above absolute zero.

Thomas Prior for TIME

The war in Ukraine has also served as a wake-up call. It is historys first hot conflict to begin with cyber-attacks, as Russia targeted vital -communications and infrastructure to lay the groundwork for its military assault. Public services, energy grids, media, banks, businesses, and nonprofit organizations were subjected to a cyberblitzkrieg, impacting the distribution of medicines, food, and relief supplies. Modern warfare and nationalsecurity mechanisms are grounded in the speed and precision of decisionmaking. If your computer is faster than theirs, you win, its pretty simple, says Spirk. Quantum is that next leap.

Read More: Exclusive: OpenAI Used Kenyan Workers on Less Than $2 Per Hour to Make ChatGPT Less Toxic

But malign intentions are just one hazard. With the U.S. embroiled in a new Cold War, its also unclear if China and Russia would adopt new NIST protocols, not least since in the past, RSA cryptography has allegedly been breached by the U.S. National Security Agency. In September, National Security Adviser Jake Sullivan said quantum would have an outsized importance over the coming decade, adding that export controls could be used to maintain U.S. advantage. Competing post-quantum security standards across Washingtons and Beijings spheres of influence have the potential to cleave the world into divergent blocs, with grave implications for global trade. [The] balkanization of what we know today as a free and open internet is distinctly possible, Inglis says.

The trepidation surrounding quantum doesnt stem solely from security risks. We trust classical computers in part because we can verify their computations with pen and paper. But quantum computers involve such arcane physics, and deal with such complex problems, that traditional verification is extremely tricky. For now, its possible to simulate many quantum calculations on a traditional super-computer to check the outcome. But soon will come a time when trusting a quantum computer will require a leap of faith. Trust building across the entire ecosystem right now is really important, says Uttley.

Boeing, for one, has been working with IBMs quantum team since 2020 on designing new materials for its next generation of aircraft. But given the colossal reputational stakes, the firm is in no rush. The modeling tools that we use to design our airplanes are closely monitored, says Jay Lowell, chief engineer for disruptive computing and networks at Boeing. To turn [quantum] into an operational code is a huge, huge hurdle.

One that IBM knows only too well. But by making its quantum computers open source, and welcoming academics and entrepreneurs from all over, the firm hopes to mitigate the hesitancy. As Gil puts it, this is a new frontier of humanity.

With reporting by Leslie Dickstein

Correction, Jan. 28

The original version of this story misstated the name of a French quantum firm. It is Pasqal, not Pascal.

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Ultra Precision Machine Tools Market Executive Summary and Analysis by Top Players 2022-2028: Fives, Moore Nanotechnology Systems, Hardinge, Inc …

The 2022-2028, Global Ultra Precision Machine Tools Market by MarketsandResearch.biz research contains Ultra Precision Machine Tools market share analysis, winning techniques, recent developments, and financials for global, regional, and top players. The study recalculates the impact of macroeconomic and microeconomic factors that have the potential to affect the growth of the Ultra Precision Machine Tools market, as well as providing data on the major players in the Ultra Precision Machine Tools industry.

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Gene Editing Tools Market 2022, Comprehensive Study With Top Companies and Key Players till 2030 This Is Ardee – This Is Ardee

New York(United States):-Global Gene Editing Tools Market is valued at approximately USD 407.88 million in 2021 and is anticipated to grow with a healthy growth rate of more than 18.00 % over the forecast period 2022-2028.

Genome editing (also known as gene editing) refers to a set of technologies that allow scientists to alter an organisms DNA. The bacteria then employ Cas9 or a similar enzyme to rip the viruss DNA apart, rendering it inoperable. In the lab, the CRISPR-Cas9 system operates similarly. The merger and acquisition among the companies and consistent technological advancements in the field of genome engineering tools have led to the adoption of Gene Editing Tools across the forecast period.

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For Instance: In January 2022, Pfizer, a multinational pharmaceutical and biotechnology corporation based in the U.S., signed a 4-year contract worth US$ 300 million with Massachusetts-based Beam Therapeutics, a pioneer in the development of CRISPR editing tools. In April 2021, CANbridge Pharmaceuticals, Inc., which is a renowned biopharmaceutical company, collaborated with LogicBio Therapeutics, Inc., a clinical-stage genetic medicine company. Also, with the rising awareness regarding the availability of genetically modified animals and crops and surging applications of genome engineering tools, the adoption & demand for Gene Editing Tools is likely to increase the market growth during the forecast period. However, lack of skilled professionals and high costs associated with Gene Editing Tools impede the growth of the market over the forecast period of 2022-2028.

The key regions considered for the Global Gene Editing Tools Market study include Asia Pacific, North America, Europe, Latin America and Rest of the World. North America is the leading region across the world in terms of market share owing to the presence of a robust commercial and research base for the development of advanced therapies. Whereas, Asia-Pacific is also anticipated to exhibit the highest growth rate over the forecast period 2022-2028. Factors such as government is allowing CRISPR DNA Editing of Crops to Enhance Production would create lucrative growth prospects for the Gene Editing Tools Market across Asia-Pacific region.

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Major market players included in this report are:

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By Product:

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR/Cas9)

Zinc Finger Nucleases (ZFNs)

Transcription Activator-Like Effector Nucleases (TALENs)

Viral Systems

Transposon Systems

Others

By Application:

Veterinary Medicine

Cell Line Engineering

Bioremediation

Food and Brewing Development

Food Waste Management

Biosensing Development

Others

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North America

U.S.

Canada

Europe

UK

Germany

France

Spain

Italy

ROE

Asia Pacific

China

India

Japan

Australia

South Korea

RoAPAC

Latin America

Brazil

Mexico

Rest of the World

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3-Chloropropene Market- increasing demand with Industry Professionals: Dow Chemical, Solvay, NAMA Chemicals, Hanwha Chemical, Formosa Plastics, etc …

3-chloropropene-market

Glob Market Reports offers an overarching research and analysis-based study on, Global 3-Chloropropene Market Report, History and Forecast 2016-2028, Breakdown Data by Companies, Key Regions, Types and Application. This report offers an insightful take on the drivers and restraints present in the market. 3-Chloropropene data reports also provide a 5 year pre-historic and forecast for the sector and include data on socio-economic data of global. Key stakeholders can consider statistics, tables & figures mentioned in this report for strategic planning which lead to success of the organization. It sheds light on strategic production, revenue, and consumption trends for players to improve sales and growth in the global 3-Chloropropene Market.

Some of the key manufacturers operating in this market include: Dow Chemical, Solvay, NAMA Chemicals, Hanwha Chemical, Formosa Plastics, Momentive Specialty Chemicals, Sumitomo Chemical, Tamilnadu Petroproducts, LOTTE Fine Chemical, Aditya Birla Chemicals, Shandong Haili Chemical Industry, Jiangsu Yangnong Chemical, Ningbo Huanyang Chemicals, Jiangsu Haixing, Dongying Liancheng and More

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Market split by Type, can be divided into: Above 99.9% 99.8%~99.9% 99.5%~99.8%Market split by Application, can be divided into: Home Appliance Coating Others

Regions Covered in the Global 3-Chloropropene Market:1. South America 3-Chloropropene Market Covers Colombia, Brazil, and Argentina.2. North America 3-Chloropropene Market Covers Canada, United States, and Mexico.3. Europe 3-Chloropropene Market Covers UK, France, Italy, Germany, and Russia.4. The Middle East and Africa 3-Chloropropene Market Covers UAE, Saudi Arabia, Egypt, Nigeria, and South Africa.5. Asia Pacific 3-Chloropropene Market Covers Korea, Japan, China, Southeast Asia, and India.Years Considered to Estimate the Market Size:History Year: 2015-2022Base Year: 2022Estimated Year: 2022Forecast Year: 2022-2028

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Key highlights of the 3-Chloropropene Market report: Growth rate Renumeration prediction Consumption graph Market concentration ratio Secondary industry competitors Competitive structure Major restraints Market drivers Regional bifurcation Competitive hierarchy Current market tendencies Market concentration analysisCustomization of the Report: Glob Market Reports provides customization of reports as per your need. This report can be personalized to meet your requirements. Get in touch with our sales team, who will guarantee you to get a report that suits your necessities.

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3-Chloropropene Market- increasing demand with Industry Professionals: Dow Chemical, Solvay, NAMA Chemicals, Hanwha Chemical, Formosa Plastics, etc ...

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