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Anatomy of a Campaign – Jacobin magazine

Posted: June 21, 2017 at 10:41 am

The leadership campaign, especially the first one, and the general election campaign weve just had, are expressions of the same phenomenon but there are distinct features of each. I think there was a tendency among political commentators to regard what happened in 2015 in the Labour Party as if it was a political nervous breakdown, as if everybody in the Labour Party had lost their minds, or it was a takeover of the party by entryists.

There was no evidence for a takeover, because there werent enough people who came into the Labour Party to outnumber existing members anyway, but the first one persisted. There was this sense that there may be an anti-austerity movement and an antiwar movement that animated people on the left, but this is restricted to a tiny group of people. I remember seeing Julia Hartley-Brewer on Sky News saying everybody who would vote for Jeremy Corbyn was already a member of the Labour Party, this is when we had about five hundred thousand people in the Labour Party.

The general election has completely destroyed that idea. Political analysts, right up even to professors, looked at the Labour Party as if it was some kind of controlled experiment, apart from society, a closed organization in which phenomena can take place where theres no read across. In actual fact, the Labour Party is part of society, predominantly not well-off people, but those who may be in education, or working in the public sector, or who are experiencing pay restraint in the private sector or who are in trouble with housing.

The issues which animated Jeremy Corbyns campaigns, both the general election and the leadership elections, were real ones that affected people in the Labour Party and continue to affect people who arent in the Labour Party. This is actually a generalized phenomenon, millions of people feel the pressures that propelled Corbyn to the leadership of the Labour Party.

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Anatomy of a Campaign – Jacobin magazine

Recommendation and review posted by Guinevere Smith

Anatomy of a combat sports tragedy: Who killed Tim Hague? –

Posted: June 21, 2017 at 10:41 am

The first time Tim Hague went down against Adam Braidwood was a little over a minute into the first round. Backed into the corner, he took a pair of right hands and ended up kneeling on the canvas, rising to his feet as the referees count hit seven.

Roughly a minute after that Hague went down again. Then shortly after he took a few more hard shots and went lunging toward Braidwoods legs not a knockdown, according to referee Leon Koivisto, but still it prompted a brief pause in the action. As soon as it started again, Braidwood put Hague down for a third time with the first punch he threw a jab.

That probably should have been the end of the fight. If it had been, Hague would probably be alive today.

Hague had looked out of his depth from the beginning. A veteran of more than 30 professional MMA bouts, he came into this fight just 1-2 as a boxer. With his labored, lunging punches, he never seemed to threaten the 7-1 Braidwood, who battered Hague with heavy right hands throughout the first round, before knocking him out cold with an uppercut early in the second.

Hague was clearly in bad shape as he lay on the canvas. He never recovered. As Braidwood told an interviewerfor Canada-based CTV News days later, I knew, man. I knew in the ring.

Two days later, Hague was taken off life support, dead at 34.

This isnt supposed to happen, even in combat sports, but we know that it can. When human beings trade head trauma for sport, the risk of a worst-case scenario becoming reality is never that far away.

According to Braidwood, Hagues death was nobodys fault. Thats true in the sense that death is a possibility that cant be completely removed from sports like boxing and MMA.

But in this case we also see several small mistakes that piled up on top of each other. Its hard to blame Hagues death entirely on any one of them certainly weve seen fighters live through worse, and even thrive afterward but together they created the atmosphere that made a possible tragedy much more likely.

For starters, theres the question of how they got in the ring together in the first place. Braidwood was 7-1 with six knockouts when he met Hague, who was 1-2 as a boxer, but 21-13 as an MMA fighter.

The damage had started to pile up late in Hagues MMA career. He lost three of his last four MMA bouts, all by knockout. Between boxing and MMA, he was knocked out three times in 2016. And his one win as a professional boxer? It was in 2011, the same year he had his final fight with the UFC.

A fight with Braidwood wasnt exactly unsanctionable, even if the matchup seems different now that we know the outcome. He was riding a six-fight winning streak compared with Hagues two-fight losing skid as a boxer, but then there was also Hagues MMA experience to consider.

Just as the Nevada State Athletic Commission can justify allowing Conor McGregor to box Floyd Mayweather based on his experience in a similar combat sport, the Edmonton Combative Sports Commission could do the same here. But a fight like that should still warrant in close look in action, just in case a marked skill discrepancy shows up right away.

Which, of course, it did. Braidwood was clearly the better boxer, a fact thoroughly established by the time he drops Hague with a jab for the third knockdown of the first round. Thats where Koivisto, the referee, could have intervened. When Hague went back to his corner after the bell, his corner had a similar chance to step in.

Nobody did. They let him go back out for the second round despite seeing little in the first to suggest that the fight would be the least bit competitive. Hagues balance, along with his ability to defend himself, were visibly compromised. He seemed doomed to defeat. So why let him get off the stool and walk back out there?

Theres more than one answer to that question, and I suspect most of them are familiar to longtime followers of the fight game. They let him go back out there because it was his choice, because he wanted to. Because he trained so hard and this was his chance. Because it wasnt over yet, and more shocking turnarounds have happened before. Because anything can happen in a fight, right?

They also let it continue because a certain amount of trauma and damage is to be expected. This is fighting, after all. We take some degree of imminent physical danger for granted. A willingness to take a beating every now and then is the price of entry. Its quitting thats a mortal sin.

Those underlying assumptions dont mix well even a few small mistakes. A ref who regards three knockdowns in the opening round as no great cause for concern. A commission willing to greenlight a risky pairing. A corner that wont tell their fighter when hes had enough.

Theyre all pieces of the puzzle here. Its just that we seem to have a hard time seeing how they fit together until its too late.

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Anatomy of a combat sports tragedy: Who killed Tim Hague? –

Recommendation and review posted by Guinevere Smith

Dr. Vincent Giampapa’s Global Foundation for Human Aging Research Donates $50000 to The Sinclair Lab at Harvard … – PR Newswire (press release)

Posted: June 21, 2017 at 10:41 am

MONTCLAIR, N.J., June 21, 2017 /PRNewswire/ –“The mission of the Sinclair Lab is exactly in line with the mission of our foundation,” says Dr. Vincent Giampapa, founder of the Global Foundation for Human Aging Research, “and that’s why we’ve donated $50,000 to its ongoing efforts.” The Sinclair Lab website states it studies the processes that drive aging and age-related diseases, and works toward discovering methods for slowing down or reversing these processes. Work ranges from dissecting novel pathways and identifying target genes, to assessing small molecules that may slow the pace of aging and increase healthspan.

Dr. Giampapa met Harvard Medical School Department of Genetics faculty member and Sinclair Lab founder Dr. David Sinclair earlier this year and was impressed with his work on NMN a molecule that appears to protect against DNA degradation and positively impact aging in mice. According to the Harvard Gazette, human trials of NMN could begin this year.

“I believe the faculty at the Sinclair Lab is doing first rate work that will have major global impact, and that’s why the foundation is supporting their mission,” says Dr. Giampapa. “Shifting our health care system into a ‘prevention and wellness’ mode will require new technologies and treatments, and those treatments must go beyond symptom suppression. Dr. Sinclair’s work with NMN is an example of this forward-thinking approach.”

The major challenges facing health care systems in the future will be demographic in nature, which underscores the need for a paradigm shift on how medical professionals think about aging. According to the Pew Research Center, global population growth will slow significantly between now and 2050. Consequently, the share of people over age 65 will increase. Some regions will feel this more than others; East Asia, for instance, is already facing stiff challenges in how to care for its aging populations. For his part, Dr. Giampapa sees the Sinclair Lab’s work as part of the solution to this slow-motion crisis.

Using Dr. Sinclair’s “ICE Mice Model,” which measures a compound’s anti-aging effects even at the genetic level, Dr. Giampapa believes companies have a promising, accelerated way of testing natural compounds’ potency and efficacy without having to wait a lifetime for human tests. Many natural compounds may have significant effects on slowing human aging, which makes this accelerated testing methodology critical.

“I look forward to witnessing new technologies help the world’s aging population experience a better quality of life, lower health care costs, and reduced dependence on prescription drugs,” concludes Dr. Giampapa.

About the Global Foundation for Human Aging ResearchThe Global Foundation for Human Aging Research is a nonprofit organization working to support the front lines of medical research and development related to the biology of human aging with the goal of improving healthspan for aging populations worldwide. It contributes funds to other non-profit institutions, universities, and companies that are working in line with its mission. It was founded by renowned anti-aging medicine pioneer Dr.Vincent Giampapa, M.D., F.A.C.S.

Contact:Laura Martinez [email protected]

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Dr. Vincent Giampapa’s Global Foundation for Human Aging Research Donates $50000 to The Sinclair Lab at Harvard … – PR Newswire (press release)

Recommendation and review posted by Guinevere Smith

World’s oldest super fruit delivers super anti-aging protection – Personal Liberty Digest

Posted: June 21, 2017 at 10:41 am

Goji berries are fairly new to the Western world, but theyve actually been around for more than 2,000 years. Legend claims they were favored by monks who lived high in the Himalayan mountains. Steeped in water, these miraculous berries were reputed to help in meditation and deliver health, energy, vitality and longevity to those who consumed them. Who doesnt want that?

The Chinese called them wolfberry fruit, and used them for their medicinal properties since around 200 B.C. Their benefits are detailed in the oldest known book on Chinese medicine, which records the medicinal knowledge and practices of the mythical Chinese emperor, Shen Nong.

The myriad of reputed attributes of goji berries have persisted through the centuries and withstood the scrutiny of science. We now know that goji berries which boast plenty of fiber, an abundance of antioxidants and more than 20 different vitamins and minerals can naturally treat all sorts of health concerns.

Goji berries are loaded with antioxidants, whose claim to fame is their ability to neutralize free radicals those un-neighborly molecules that, missing an ion, attack nearby molecules to steal one.

Of course, that leaves a robbed molecule with an uneven number of ions, turning it into another free radical and launching a frenzied, destructive chain reaction of molecule attacks.

Because free radical damage is a major cause of aging and disease, antioxidants are essential for good health and longevity. The goji berry is rich in health-promoting, antioxidant carotenoids: beta-carotene, lycopene, beta-cryptoxanthin, zeaxanthin and lutein.

The ORAC (Oxygen Radical Absorbance Capacity) table measures the antioxidant value of fruits and vegetables. The ORAC shows one ounce of goji berry juice has 10 times more free-radical destroying ability than most other fruits and vegetables. Comparatively, goji berries outstrip oranges for vitamin C, carrots for beta carotene and steak for iron. They have four times more potassium than bananas, and theyre loaded with vitamin C and zinc, both powerful health protectors.

The goji berrys ORAC score puts it in the same class as other superhero, super fruits such as Acai berries, Hawaiian Noni and Mangosteen.

Goji berries contain 18 amino acids, 21 trace minerals (zinc, iron, calcium selenium and phosphorus) and five unsaturated fatty acids (including linoleic and alpha-linolenic acids).

The antioxidants found in goji berries may protect you not only against free radicals but also against oxidative stress and inflammation (the damage free radicals cause). The vitamin C content of goji berries not only helps the common cold but helps wrinkled and sagging skin, cholesterol, blood flow, blood sugar plus, heart, cell and eye health.

Carotenoids convert to vitamin A, which boosts your immune system, eye health and helps build strong bones and teeth.

By preventing damage from UV light exposure and free radicals, the antioxidants zeaxanthin and lutein protect against age-related blindness.

The power of goji berry juice can protect your skin from free radical damage caused by sun exposure. It even provides photoprotection for those who are vulnerable to developing diseases of the skin.

Combined with a healthy diet, goji berries provide a natural approach to blood sugar by helping insulin. For people with blood sugar concerns, dried goji berries provide a preferable snack alternative to high-sugar processed foods.

Goji berries also improve liver and kidney detoxification, energy levels and fertility.

Want more? This super fruit can help support weight loss, boost energy levels, increase your resistance to fatigue, improve focus, strengthen your immune system and enhance sleep quality.

The next time you want a snack, pass on the potato chips and give your body a bonanza of health benefits by choosing dried goji berries. Or get your antioxidant boost every day by taking a high-quality supplement like Peak ResV+ Superfruits. It contains, not only Goji berry but Resveratrol, Acai, Hawaiian Noni, Mangosteen and six other super fruit, superheroes.

Sources: Axe, J. Goji Berry Benefits: Antioxidant & Anti-Inflammatory Superfruit. goji-berry-benefits.

Benefits of Goji Berries: The Chinese Longevity Fruit. Antioxidants-for-Health-and-Longevity.

Chinese Wolfberry Benefits & Doses. SFGate.

Rupavate, S. 15 ways Vitamin C keeps you healthy and fit! The Health Site. Aug. 3, 2015

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World’s oldest super fruit delivers super anti-aging protection – Personal Liberty Digest

Recommendation and review posted by Fredricko

Will patients’ lifestyles become more important to precision medicine than gene sequencing? – Genetic Literacy Project

Posted: June 20, 2017 at 8:44 am

While much of the excitement surrounding precision medicine focuses on using genomics to tailor personalized treatment plans, speakers at the Precision Medicine Summit said theres more to it.

We cannot achieve precision medicine without having everyone be a participant and benefit and understand, said India Barnard-Hook, director of strategy and associate director of precision medicine at University of California, San Francisco. Precision medicine is about much more than genomics.

Social determinants of health, for instance, typically occur outside the healthcare system and have a significant impact on both health and individual outcomes.

You have to know a lot more than the clinical phenotype, said Linda Chin, chief innovation officer for health affairs at The University of Texas Health System.If you understand all the other factors that contribute to diseases, those can alter the course of the disease and ultimately prevent it.

Penn Medicine associate vice president of health technology and academic computing Brian Wells even made the bold prediction that genetic sequencing may become less relevant as cancer treatments become increasingly sophisticated.

If we discover one immunotherapy that applies to all cancers, we really dont need to sequence your genome anymore, Wells said. Were at a tipping point and sequencing could become less important.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post:With precision medicine, social determinants could be more insightful than genetics

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Will patients’ lifestyles become more important to precision medicine than gene sequencing? – Genetic Literacy Project

Recommendation and review posted by Guinevere Smith

GE and the Mayo Clinic back software to bring cancer-fighting gene therapies to market – TechCrunch

Posted: June 20, 2017 at 8:44 am

GE and the Mayo Clinic back software to bring cancer-fighting gene therapies to market
So GE (through its GE Ventures arm), the Mayo Clinic (through Mayo Clinic Ventures) and the venture investment firm DFJ have invested $13.75 million to back Vineti a software platform that the companies are billing as a solution to gene therapy's
GE Ventures, Mayo Clinic Ventures and DFJ Invest $13.75M in First Software Platform to Accelerate Cancer Cure …GlobeNewswire (press release)

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GE and the Mayo Clinic back software to bring cancer-fighting gene therapies to market – TechCrunch

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