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Pharmacogenomics – NCPA

Posted: March 2, 2018 at 6:48 pm

General Description, Overview, and Opportunities

Pharmacogenomics has increasingly become an area of interest to clinicians because of the potential to tailor pharmacotherapy based on genetic variations in patients. Pharmacogenomics is one of the key aspects of personalized medicine, focusing on how an individual’s DNA affects the way they respond to medications. All individuals have different genetic make-up so they respond differently to the same medication. Based on this insight, pharmacogenomics allows customized treatment for a wide range of health problems including; cardiovascular disease, Alzheimer’s disease, cancer, HIV/AIDS, and asthma. Often, drug choice and dosage require experimentation (trial and error) in order to find the best treatment option. With pharmacogenomics testing, the need for this experimentation is decreased. As a result, the process becomes faster and more cost-effective and the possibility of adverse events caused by the wrong drug choice or dosage is significantly reduced.

One avenue for implementing pharmacogenomic is through medication therapy management (MTM), where pharmacists assess and evaluate a patient’s complete medication therapy regimen. By gathering key pieces of information, e.g. which medications and supplements a patient is currently taking, pharmacists can assess current treatment and suggest alternative therapies.

As medication experts and POC service providers, pharmacists can educate physicians and patients and perform the actual sample collection to be utilized for genetic testing. The broad application of pharmacogenomics to personalized medicine will improve patient outcomes and lower healthcare costs.

Test Features

Pharmacies require a lab partner to provide clinically relevant data and interpret results for physicians. Most tests screens all well-established pharmacogenomics genes in a single, cost-effective test. Results are delivered quickly via intuitive, clinically relevant, medically actionable report. The data provides lifetime utility of data, thereby decreasing the need for future testing.

Community pharmacists routinely perform point of care services and can assist patients by:

Performing a buccal swab in minutes

Send the collected DNA to the lab

Interpret results and discuss with physicians

Contact the patient to explain the results and any changes in therapy


Pharmacist Resources and Training

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Pharmacogenomics – NCPA

Recommendation and review posted by G. Smith

NSI Stem Cell | Stem Cell Therapy Injection Treatment

Posted: March 2, 2018 at 6:47 pm

The process begins first with a physical exam and in depth patient history. We do this to give you the best proper diagnosis and treatment. If additional information is needed, we will conduct the necessary imaging or laboratory reports. We will then discuss patient desires and expected outcomes as well as educate on his/her condition and all possible treatment options.

The Stem Cell procedure is minimally invasive, gathering a sample of adipose tissue from the abdomen. Theses cells remain sterile and after adult stem cells are extracted, they will be readministered back into the patient. This is done by one of the three methods: Intravenous, Intranasal or Localized.

Our Autologous Adipose Stem Cell producer is safe and there are no instances of cell rejection or disease transmission because the adipose extracted always remains in a sterile environment. In addition, all aspects of the procedure are performed in house and under a licensed physician.

Click on our Services page to learn more about the different types of therapy and treatments offered.

View the video below to learn more:

NSI Stem Cell | Stem Cell Therapy Injection Treatment

Recommendation and review posted by G. Smith

Medical Spa, Botox, OKC, Norman, Moore, South OKC, OK Longevity

Posted: March 2, 2018 at 6:46 pm

Body contouring is one of the most effective ways for patients to improve their bodies and their health. Because we understand that what each patient wants to get out of a body contouring procedure is a little different, Longevity Aesthetics and Laser Spa offers our patients access to a comprehensive range of treatments, including:

CoolSculpting. This non-surgical method of fat removal uses controlled cooling to freeze fat cells in nearly any area of the body, causing them to rupture and die. Once these fat cells have been destroyed, they are removed from the body, leaving behind a tighter, toner physique.

Thermi250. With Thermi250, patients can target loose skin, excess fat, and cellulite on nearly any area of the body, including the midsection, chest, arms, back, thighs, and chin. Because this procedure uses the gentle power of radiofrequency energy, patients experience little to no discomfort before, during, or after treatment.

HCG Diet. This weight loss program combines a low-calorie diet and Human Chorionic Gonadotropin injections to speed up weight loss while leaving lean muscle fully intact.

SkinTyte. Non-invasive SkinTyte treatments can be utilized to help patients achieve smoother, tighter, firmer skin on the hands, arms, and abdomen with little to no downtime. This technique is clinically proven to be safe for patients of all skin types.

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Medical Spa, Botox, OKC, Norman, Moore, South OKC, OK Longevity

Recommendation and review posted by G. Smith

Integrative Medicine Fellowship – KUMC

Posted: March 2, 2018 at 3:43 am

The objective of the Integrative Medicinefellowship is not to train conventional practitioners to fully practice a CAM discipline. It is, rather, to create a practitioner who is knowledgeable enough about integrative care to function as a skilled guide/adviser to the patient and a collaborative member of multidisciplinary and integrative patient care teams – one who can work effectively with both CAM and conventional practitioners.

The fellowship provides a year’s intensive exploration of clinical, educational and research activities related to integrative medicine for MDs or DOs who have satisfactorily completed their residency training.Although fellowship candidates need not be experienced in integrative medicine, they must have shown a recent documentable interest in the field (courses taken, conferences attended, self-paced learning, clinical experiences, etc.).

Fellows will average two days a week in clinical care at integrative clinics, two days in educational pursuits related to integrative medicine, and one day on research in integrative medicine. With the approval of the program director, this schedule can be revised to meet a fellow’s individual educational goals.

Fellows will contribute to the continuous quality improvement of the program by helping to build a library of case studies and teaching materials, by performing research, and by giving feedback on the program itself at the end of their fellowship year.

Application Open Date: August 2018

Application Due Date: January 15, 2019

Send applications via email to [email protected] with “Fellowship application” in the subject line.

Applications should include:

Upon completion of the fellowship, participants should be able to:

Last modified: Dec 15, 2017

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Integrative Medicine Fellowship – KUMC

Recommendation and review posted by G. Smith

Anti-Aging Center Portland – Aesthetic Medicine Specialist …

Posted: March 2, 2018 at 3:41 am

At Thrive, the natural progression of your transformation is as important to us as are the results. We like to say that everyone will notice, but no one will know. Your personal image is up to you to establish, and we can help you fine-tune the appearance of your face and body so that you feel confident in your own skin.

Our practice serves the areas of Portland, Beaverton, Lake Oswego, Tigard, Milwaukie, Clackamas, Oregon City, and Vancouver, with the latest technology and scientifically proven products for healthy skin and bodies. We have more than ten years of experience in the area of anti-aging, and maximize the potential of many FDA-approved treatments for your benefit.

More than offering an array of anti-aging services, we provide personalized care by getting to know our individual patients. We want to hear your aesthetic concerns, and your ideas on how you would like to traverse the aging process. When we know your issues and desires, we can tailor a treatment plan unique to you, so that you gain the most benefit from any given procedure. Our staff has the extensive training and hands on experience you deserve, and we incorporate the latest, proven treatments for your benefit.

In addition to assembling proven non-surgical treatments, Thrive is also staffed with extensively trained, clinically experienced practitioners, including a board certified plastic surgeon, spanning areas such as weight loss, and integrative anti-aging medicine using advanced anti-aging methods, including lasers, as well as internal naturopathic approaches. The Thrive team is here to help you achieve your goals through personalized treatment tailored appropriately to you. Here, you will benefit from our level of expertise and integrative approach to well-being.

If you live in the Portland area, and want to gain control over your own aging process, we invite you to come by for a complementary consultation.

Thrive. Age Beautifully!

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Anti-Aging Center Portland – Aesthetic Medicine Specialist …

Recommendation and review posted by G. Smith

Resveratrol: Benefits and Uses –

Posted: February 28, 2018 at 4:43 pm

Found in red wine, red or purple grapes, some berries,and dark chocolate, resveratrol is a naturally-occurring polyphenol compound that has been touted as a potential remedy for a range of age-related conditions, including heart disease, diabetes, cancer, and Alzheimer’s disease.

Said to contribute to the “French paradox”the observation that people living in France tend to eat a lot of cheese, butter, and other fatty foodsyet have a low incidence of heart diseaseresveratrol consumption has been found to mimic a calorie-restricted diet (which studies have shown can play a role in longevity) and decrease chronic inflammation in the body.

Much of the research pointing to the benefits have been laboratory or animal-based studies. So far, research on resveratrol’s effectiveness in humans has yielded mixed results. Here’s a look at some key study findings:

1) HeartHealth

For a review published in Clinical Nutrition in 2015, researchers analyzed six previously published studies on the effects of resveratrol on blood pressure, and concluded that resveratrol didn’tsignificantly reduce blood pressure. Higher doses of resveratrol (over 150 mg per day), however, werefound to significantly decrease systolic blood pressure (the top number on a blood pressure reading).

Another review, published in the International Journal of Cardiology in 2015, examined the effectiveness of resveratrol on cardiovascular risk factors. After analyzing 10 previously published studies, researchers concluded that the analysis did not suggest any benefit of resveratrol supplementation on heart disease risk factors, including levels oftotal cholesterol, LDL cholesterol, triglycerides, blood pressure, and C-reactive protein (a blood protein that is raised when there is inflammation, including in heart disease).

2) Aging

There’s some evidence that resveratrol may not prolong life, according to research on people living in Tuscany who consume a diet rich in resveratrol from food sources like red wine. In astudy published in JAMA Internal Medicine in 2014, 783 men and women 65 years or older were followed from 1998 to 2009.

During that time, intake of red wine (as measured by urine levels of resveratrol metabolites), didn’t change the likelihood of dying from any cause, the incidence of heart disease or cancer, or markers of inflammation.

3) Cancer

A number of preliminary studies suggest that resveratrol may have anti-cancer effects. In a2016 animalstudy, for instance, resveratrol suppressed ovarian tumor regrowth after chemotherapy. Published in Cancer, the study found that resveratrol inhibited the uptake of glucose by cancer cells (many cancer cells depend on glucose as their energy supply).

Despite these findings, the data from the limited human clinical trials have shown inconsistent outcomes and the American Cancer Society cautions that randomized clinical trials are needed to confirm the cancer-fighting effects of resveratrol. (There is also some concern that resveratrol may influence levels of estrogen and other hormones.)

Trans-resveratrol is a form of resveratrol commonly found in supplements. Proponents often claim that trans-resveratrol is the most stable form of resveratrol.

In addition to food sources, resveratrol is also found in Japanese knotweed (Polypodium cuspidatum), grape seed extract, cissus quadrangularis, and white mulberry (Morus alba).

Pterostilbeneis a compound related to resveratrol.

LIttle is known about the safety of long-term or high dose use of resveratrol.

Since resveratrol may possess estrogen-like properties, some medical experts recommend that people with hormone-sensitive cancers (including cancers of the breast, ovary, or uterus), pregnant women, and children avoid taking resveratrol.

In addition, resveratrol could interact with blood thinners like warfarin, aspirin, and ibuprofen, which may raise your risk of bleeding.

According to one study, high-dose resveratrol supplementation was associated with fever,reduced blood cells, and decreased blood pressure.

There is some concern that high doses ofresveratrol supplements could lead to kidney problems in some people.

Supplements haven’t been tested for safety and due to the fact that dietary supplements are largely unregulated, the content of some products may differ from what is specified on the product label. You can get tips on usingsupplementshere.

Since the compound was first described in 1992, resveratrol has been studied for its much-touted benefits on the brain, heart, and lifespan, but recent research casts doubt on the notion that resveratrol supplementscan help you live longer or lower your risk of heart disease or cancer.

If you’re wondering whether a daily glass of red wine or piece of dark chocolate will improve your health, some researchers note that consumption of red wine, dark chocolate, and some berries has been found to decrease inflammation and have heart-healthy benefits, and suggest that other compounds in these foods may contribute to these benefits.

It’s impossible, however, to get anywhere near the doses used in studies from food sources. Many of the studies have used a dose of about 100 mg or more of resveratrol, while a 5-ounce glass of red wine only has about 1 mg of resveratrol.

It’s important to note that increasing your intake of red wine comes with a trade-off.Consuming too much may raise your risk of high bloodpressure, liver damage, obesity, and some forms of cancer.

To boost your intake without consuming alcohol, try eating foods like grapes, raspberries, plums,blueberries, cranberries, grape tomatoes, and pomegranate (all of which are rich in resveratrol and a range of antioxidants and nutrients).

If you’re still considering using resveratrol supplements, talk to your healthcare provider before starting your supplement regimen to weigh the pros and cons and discuss whether it’s appropriate for you.


Liu Y, Ma W, Zhang P, He S, Huang D.Effect of resveratrol on blood pressure: a meta-analysis of randomized controlled trials.Clin Nutr. 2015 Feb;34(1):27-34.

Sahebkar A, Serban C, Ursoniu S, et al.Lack of efficacy of resveratrol on C-reactive protein and selected cardiovascular risk factors–Results from a systematic review and meta-analysis of randomized controlled trials.Int J Cardiol. 2015;189:47-55.

Semba RD, Ferrucci L, Bartali B, et al.Resveratrol levels and all-cause mortality in older community-dwelling adults.JAMA Intern Med. 2014 Jul;174(7):1077-84.

Tan L, Wang W, He G, et al.Resveratrol inhibits ovarian tumor growth in an in vivo mouse model.Cancer. 2016 Mar 1;122(5):722-9.

Disclaimer: The information contained on this site is intended for educational purposes only and is not a substitute for advice, diagnosis or treatment by a licensed physician. It is not meant to cover all possible precautions, drug interactions, circumstances or adverse effects. You should seek prompt medical care for any health issues and consult your doctor before using alternative medicine or making a change to your regimen.

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Resveratrol: Benefits and Uses –

Recommendation and review posted by G. Smith

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