Category Archives: BioEngineering

SCOTTSDALE, AZ, Feb. 07, 2020 (GLOBE NEWSWIRE) -- via NEWMEDIAWIRE Electromedical Technologies, Inc. (OTC: ELCQ) (the Company), an innovative medical technology company, commented today concerning use of the Companys Wellness Pro Plus, to aid patients suffering from the overuse and misuse of prescription drugs to fight opioid addiction. The Wellness Pro Plus is a non-invasive medical device used to address chronic, acute and intractable pain. The Companys Wellness Pro Plus is a viable alternative to prescription opioids for patients suffering with chronic or debilitative pain, is FDA-cleared and backed by over 10 years of successful healthcare treatment and many patient testimonials.

Matthew Wolfson, Founder and CEO of the Company, commented, "Our Wellness Pro Plus is our prescription-strength bioelectronics flagship device that has been helping many patients around the world live a better quality of life. We look forward to expanding awareness of our Wellness Pro Plus and of our new upcoming line of products so that medical practitioners and patients have an option for an organic, non-toxic and non-invasive solution to chronic pain.

Wolfson continued, The Wellness Pro Plus can be used as the first line of defense to manage pain, instead of medication harboring numerous negative side effects. Patients are less likely to start a path to opioid reliance when drug-free options are available. People must have choices.

Prescribing the use of the Wellness Pro Plus for long term pain relief is an easy and simple process for health care practitioners. The device is designed to use electrotherapy and frequencies in order to promote endorphin release (the bodys natural morphine) to help relieve chronic pain without the use of drugs, and in many cases provides relief instantly. The Company is now focusing on expanding its sales force and marketing aggressively in rural and urban areas. (To see a video explaining how the Wellness Pro Plus works, click here.)

A published article Why It's Time to Take Electrified Medicine Seriously by Time Magazine observed: The remarkable convergence of advances in bioengineering and neurology has resulted in a fast-developing way to treat chronic diseases, known as bioelectronic medicine. These advances allow scientists to identify specific nerves and implant devices that can be activated when needed to stimulate or dial down their activity; that in turn controls cells in organs targeted by those nerves that regulate the bodys many immune and metabolic responses. (To read the full article, click here.)

The Company believes that biofrequency medicine is the future and will be the norm alongside pharmaceuticals within the next 5 years.

Electromedical Technologies, Inc. will also be releasing its WellnessPRO POD projected for release in 2021. The WellnessPRO POD is intended to address anxiety, depression, and insomnia, in addition to all the other benefits the Wellness Pro Plus can provide, by using electronic frequencies that naturally affect the body.

About Electromedical Technologies, Inc.

International bioelectronic device pioneer, ElectroMedical Technologies, assembled a team of leading scientists from around the world in 2004 with a mission for improving the quality of life and wellness of people suffering from chronic and acute pain. In 2007, with FDA clearance, ElectroMedical delivered its first intelligent portable bioelectronic medicine therapy device, WellnessPro Plus, which provides faster, lasting pain relief using proprietary DeepPulse technology. WellnessPro Plus is FDA-cleared and Mexico Cofepris certified to treat chronic, intractable, post-surgical or post-traumatic acute pain. With more than 10 years in business, WellnessPro Plus is used by health care professionals, athletes, coaches and medical research facilities around the world. For more information, visit http://www.electromedtech.com.

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Electromedical Technologies, Inc. Addresses America's Opioid Crisis with its Wellness Pro Plus - GlobeNewswire

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Key Players Analysis:Royal DSMLonza Group LtdCellana, Inc.Rishon International GroupHubei Fuxing BiotechnologyRunke Biological Engineering CompanyCargill Alking Bioengineering (Wuhan)

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Algae Oil Omega-3 Market by Types, Applications, Countries, Companies and Forecasts to 2025 covered in a Latest Research - Instant Tech News

A Belgian child prodigy who is the world's youngest person to receive an undergraduate degree is eager to continue his education in Israel.

Israeli ambassador to Belgium with Laurent Simons

(Photo: Israeli Embassy, Brussels)

Nine-year-old Laurent Simons of Belgium has approached the Israeli embassy in Brussels, saying he would like to explore his possibilities for advanced studies in Israel.

Laurent is especially interested in biotechnology, medicine, and bioengineering, and hopes to study these subjects in tandem so that he can fulfill his dream of designing prosthetic organs when he grows up.

Earlier this week, his parents met with Ambassador Emmanuel Nahshon.

They said they had heard good things about academic studies in Israel and believe their son would thrive in his career and enjoy a community suitable for a ten-year-old boy.

Laurent himself expressed an interest to study various scientific fields, but would first like to master the Hebrew language.

Nahshon told the Simons family that he would convey their interest to universities in Israel.

"It is a source of pride that this child has chosen to study in Israel," Nahshon said. "It shows he is not only a genius but also really smart."

Though they have never visited Israel, Laurent's family has heard about its beauty and advanced high-tech industry, and say they are excited at the prospect of seeing it.

Laurent's undergraduate degree is in electronic engineering from the Eindhoven University of Technology and he intends to advance directly to a Ph.D. program.

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World's smartest child wants to study in Israel - Ynetnews

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The first annual conference of Please Try This at Home took place in September 2019. At the cross section of biotechnology, body autonomy and anarchy, the conference represents an inclusive group of scientists concerned with using and discussing biotechnology in the hopes of moving the field in a more progressive direction. That being said, it is indeed a solid step in the right direction, especially when one takes into consideration how misunderstood the bioengineering field has become.

To get a sense of the state of bioengineering, a biohacker by the name of Josiah Zayner livestreamed an attempt to splice his DNA to give himself bigger muscles. If it was inserted in the wrong place in his body, or in the wrong place for the code, his DNA could end up producing weakened or ineffective proteins that could affect his body functionality. While that attempt was misguided and Zayner later regretted the stunt, the implication was that this technology should be safe and easy, which is a dangerous and untrue belief to hold. As biotechnology continues to improve, more research and regulation will be needed to ensure the safety of its use.

Ensuring said safety requires a basic understanding of cellular biology, and at its core is the central dogma of molecular biology. Simply put, most genetic material is encoded in DNA, DNA transcribes to RNA and RNA translates to proteins and those proteins are responsible for most functions in the body. Generally, bioengineering works by taking a segment of foreign DNA and inserting it into the rest of the genetic code, resulting in a production of proteins that will carry out a function specific to that DNA code. The described process is extremely complex and delicate, but despite that, genetic engineering has been used to treat Parkinsons disease and sickle cell disease among others.

That said, genetic engineering has a promising future outside of simple disease treatment. To reaffirm the purpose of Please Try This at Home, genetic engineering could be used for a different form of hormone therapy for transgender individuals. In a mostly speculative procedure, a geneticist could activate the necessary genes responsible for production of a specific hormone. That being said, it is important to keep in mind that this is a hypothetical experiment, and could result in potentially greater health problems later in life. These potential problems necessitate the need for greater experimentation and regulation in order to work out the difficulties.

Experiments in gene editing on a larger scale have already been proposed to fight Lyme disease. Normally, the disease spreads when a tick bites a mouse, followed by that tick biting a human. On Nantucket Island and Marthas Vineyard, where Lyme disease is particularly virulent, a project called Mice Against Ticks is under consideration, in which mice would be genetically modified to be able to resist and prevent the spread of Lyme disease. Kevin Esvelt, the scientist spearheading this operation is also acutely aware of the potential ecological ramifications of this project, cautiously choosing an isolated island with a low human population and low chances of dispersal if the project goes awry.

Esvelts caution in choosing an experimental site calls to mind the dangers of genetic engineering: the long term effects are not yet fully known, and it is understandable to be afraid of something that is not entirely explored. The chances of cascading ecological effects from genetic engineering is as present as the possibility for abuse of genetic engineering via eugenics. Simultaneously, those possibilities are also matched by the potential to eradicate Lyme disease, malaria or leukemia.

The best way to ensure safer practices and better opportunities for the future of genetic engineering is to regulate its practice. Clear distinctions need to be made between biohackers, like Zayner and practical, controlled applications like Mice Against Ticks. Genetic engineering could have world changing effects; it just needs to be regulated and perfected.

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As bioengineering progresses, regulation will need to follow - Highlander Newspaper

Researchers have created a device that measures how sticky cancer cells are, which could improve prognostic evaluation of patient tumors. The device is built with a microfluidic chamber that sorts cells by their physical ability to adhere to their environment. The findings were published inCancer Research.

This new device could be the first step to better assess how likely tumor recurrence is, said Adam Engler, bioengineering professor at the UC San Diego Jacobs School of Engineering and senior author of the study in a press release. Patients with few of these aggressive cells lying dormant in their surrounding tissue may be less likely to see a tumor reoccur 5, 10, or 20 years later. Engler noted that by knowing a patients risk, follow-up treatments could be better tailored to the individual.

The device they developed includes a microfluidic chamber coated with an adhesive protein. After cancer cells adhere, they are placed in the chamber before a fluid is pushed through to detach cells. The faster the fluid moves, the higher the stress exerted on the cancer cells. The analysis led the team to another critical finding: weakly adherent cells possess a unique genetic signature that identifies them and enables them to migrate and invade faster. Comparing this signature to thousands of patients in the Cancer Genome Atlas (TCGA) database, researchers observed that patients with tumors high in this weakly adherent signature experienced tumor recurrence occurred earlier and more frequently.

First author Pranjali Beri, a bioengineering Ph.D. student in Englers lab noted that: If our mouse model shows that these cells indeed reduce cancer-free survival times, it will pave the way for substantial prognostic studies in humans with these types of solid tumors.

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A New Device that Measures the Stickiness of Tumor Cells May Improve Cancer Prognosis - DocWire News

Mucus is a protective, slimy secretion produced by goblet cells and which lines organs of the respiratory, digestive, and reproductive systems. Slime production is essential to health, and an imbalance can be life-threatening. Patients with diseases such as asthma, chronic obstructive pulmonary disease (COPD), and ulcerative colitis produce too much mucus, often after growing too many goblet cells. Loss of goblet cells can be equally devastating - for instance during cancer, after infection, or injury. The balance of slime creation, amount, and transport is critical, so doctors and medical researchers have long sought the origins of goblet cells and have been eager to control processes that regenerate them and maintain balanced populations.

Recently, a group of bioengineers at the University of Pittsburgh discovered a case of goblet cell regeneration that is both easily accessible and happens incredibly fast on cells isolated from early developing frog embryos.

Lance Davidson, William Kepler Whiteford Professor of Bioengineering at Pitt, leads the MechMorpho Lab in the Swanson School of Engineering where his researchers study the role of mechanics in human cells as well as the Xenopus embryo - an aquatic frog native to South Africa.

The Xenopus tadpole, like many frogs, has a respiratory skin that can exchange oxygen and perform tasks similar to a human lung, explained Davidson. Like the human lung, the surface of the Xenopus respiratory skin is a mucociliated epithelium, which is a tissue formed from goblet cells and ciliated cells that also protects the larva against pathogens. Because of these evolutionary similarities, our group uses frog embryonic organoids to examine how tissue mechanics impact cell growth and tissue formation.

Studying this species is a rapid and cost-effective way to explore the genetic origins of biomechanics and how mechanical cues are sensed, not just in the frog embryo, but universally. When clinicians study cancer in patients, such changes can take weeks, months, or even years, but in a frog embryo, changes happen within hours.

In this project, we took a group of mesenchymal cells out of the early embryo and formed them into a spherical aggregate, and within five hours, they began to change, Davidson said. These cells are known to differentiate into a variety of types, but in this scenario, we discovered that they changed very dramatically into a type of cell that they would not have changed into had they been in the embryo.

The lab surprisingly uncovered a case of regeneration that restores a mucociliated epithelium from mesenchymal cells. They performed the experiment multiple times to confirm the unexpected findings and began to look closely at what microenvironmental cues could drive cells into an entirely new type.

We have tools to modulate the mechanical microenvironment that houses the cells, and to our surprise, we found that if we made the environment stiffer, the aggregates changed into these epithelial cells, explained Davidson. If we made it softer, we were able to block them from changing. This finding shows that mechanics alone can cause important changes in the cells, and that is a remarkable thing.

Davidsons group is interested in how cells, influenced by mechanics, may affect disease states. The results detailed in this article may drive new questions in cancer biology, prompting researchers to consider whether certain kinds of invasive cancer cells might revert to a resting cell type based on the stiffness or softness of their surroundings.

When applying these results to cancer biology, one might ask, If tumors are surrounded by soft tissues, would they become dormant and basically non-invasive? Or, If you have them in stiff tissues, would they invade and become deadly? said Davidson. These are major questions in the field that biomechanics may be able to help answer. Many researchers focus solely on the chemical pathways, but we are also finding mechanical influencers of disease.

Hye Young Kim, a young scientist fellow at Institute for Basic Science (IBS) and former member of the MechMorpho Lab, will continue this work at the Center for Vascular Research located at Korea Advanced Institute of Science and Technology (KAIST). She will study how cell motility changes during regeneration and how epithelial cells assemble a new epithelium. Davidson and his lab will explore how this novel case of mechanical cues are sensed by mesenchymal cells and how these mechanical induction pathways are integrated with known pathways that control cell fate choices.

"Frog embryos and organoids give us unparalleled access to study these processes, far more access than is possible with human organs, he said. The old ideas that regeneration is controlled exclusively by diffusing growth factors and hormones is giving way to the recognition that the physical mechanics of the environment such as how rubbery or fluid the environment - play just as critical a role."

Reference:Kim, H. Y., Jackson, T. R., Stuckenholz, C., & Davidson, L. A. (2020). Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates. Nature Communications, 11(1). https://doi.org/10.1038/s41467-020-14385-y

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.

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Using Regenerative Biology To Restore Mucus Production - Technology Networks