Category Archives: Biochemistry

This report additionally covers the effect of COVID-19 on the worldwide market. The pandemic brought about by Coronavirus (COVID-19) has influenced each part of life all inclusive, including the business segment. This has brought along a several changes in economic situations.

The Automated Biochemical Urine Analyzers market report provides a detailed analysis of global market size, regional and country-level market size, segmentation market growth, market share, competitive Landscape, sales analysis, impact of domestic and global market players, value chain optimization, trade regulations, recent developments, opportunities analysis, strategic market growth analysis, product launches, area marketplace expanding, and technological innovations.

It incorporates Automated Biochemical Urine Analyzers market evolution study, involving the current scenario, growth rate (CAGR), and SWOT analysis. Important the study on Automated Biochemical Urine Analyzers market takes a closer look at the top market performers and monitors the strategies that have enabled them to occupy a strong foothold in the market. Apart from this, the research brings to light real-time data about opportunities that will completely transform the trajectory of the business environment in the coming years to 2025. Some of the key players in the global Automated Biochemical Urine Analyzers market is cccc

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The global Automated Biochemical Urine Analyzers market size is estimated at xxx million USD with a CAGR xx% from 2015-2019 and is expected to reach xxx Million USD in 2020 with a CAGR xx% from 2020 to 2025. The report begins from overview of Industry Chain structure, and describes industry environment, then analyses market size and forecast of Automated Biochemical Urine Analyzers by product, region and application, in addition, this report introduces market competition situation among the vendors and company profile, besides, market price analysis and value chain features are covered in this report.

Product Type Coverage (Market Size Forecast, Major Company of Product Type etc.):

Biochemical

Sediment

Microscopic

Flow-Cytometric

Company Coverage (Company Profile, Sales Revenue, Price, Gross Margin, Main Products etc.):

Beckman Coulter

Roche Diagnostics

Siemens AG

Sysmex Corporation

ARKRAY, Inc

Application Coverage (Market Size Forecast, Different Demand Market by Region, Main Consumer Profile etc.):

Diabetes

UTI

Kidney

Liver Disease

Pregnancy

Region Coverage (Regional Production, Demand Forecast by Countries etc.):

North America (U.S., Canada, Mexico)

Europe (Germany, U.K., France, Italy, Russia, Spain etc.)

Asia-Pacific (China, India, Japan, Southeast Asia etc.)

South America (Brazil, Argentina etc.)

Middle East Africa (Saudi Arabia, South Africa etc.)

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Major Point of TOC:

Chapter One: Automated Biochemical Urine Analyzers Market Overview

Chapter Two: Automated Biochemical Urine Analyzers Market Segment Analysis by Player

Chapter Three: Automated Biochemical Urine Analyzers Market Segment Analysis by Type

Chapter Four: Automated Biochemical Urine Analyzers Market Segment Analysis by Application

Chapter Five: Automated Biochemical Urine Analyzers Market Segment Analysis by Sales Channel

Chapter Six: Automated Biochemical Urine Analyzers Market Segment Analysis by Region

Chapter Seven: Profile of Leading Automated Biochemical Urine Analyzers Players

Chapter Eight: Upstream and Downstream Analysis of Automated Biochemical Urine Analyzers

Chapter Nine: Development Trend of Automated Biochemical Urine Analyzers (2020-2029)

Chapter Ten: Appendix

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Global Automated Biochemical Urine Analyzers Market Insights and Forecast 2020 to 2025 - The Daily Chronicle

Sydney Abrams (left) and Leigh Anne Clark pose with a trio of feisty Shetland Sheepdogs. Editors note: Special thanks to Debbi Kaplan, owner of Shadow Hill South Shelties, for providing the beautiful dogs shown in the photo above. From left: 10-year-old Jake, GCHB Shadow Hill The Bachelor; 2-year-old Garrett, Shadow Hill South Be The Difference; and 4-month-old Heath, Shadow Hill South The Influencer. For more information, visit http://www.ShadowHillSouthShelties.com.Image Credit: College of Science / Pete Martin

CLEMSON, S.C. When a beautiful pup has a dental problem, its time to call a veterinarian. But when it runs in the family, researchers take the case.

Clemson University researcher Leigh Anne Clark and her graduate student, Sydney Abrams, study inherited diseases in canines. They have worked previously on conditions that affect Shetland Sheepdogs, those fluffy Sheltie herding dogs that closely resemble a miniature version of Lassie. The pair collaborated on a paper titled Variants in FtsJ RNA 2-O-Methyltransferase 3 and Growth Hormone 1 are associated with small body size and a dental anomaly in dogs, which was published Sept. 21 in PNAS, the official journal of the National Academy of Sciences (NAS).

After Sheltie breeders sought answers about maxillary canine-tooth mesioversion, Clark and Abrams subsequent research led to a groundbreaking discovery.

We wanted to find the genetic basis for lance canines and ended up discovering that its related to the dogs body size, said Abrams, who is lead author on the paper. This is one of the first times a trait in dogs has been attributed directly to genes influencing growth.

The condition is known among Sheltie breeders as lance canine, added Clark, an associate professor in the College of Sciences Department of Genetics and Biochemistry. Thats because that canine tooth points forward, like a lance or spear, instead of pointing down like it should.

Some Shelties are born with lance-like canines that have to be corrected or removed so that the dog can live a healthy life.Image Credit: Photo courtesy of Mary Mahaffey

The tooth can be extracted or fixed with orthodontics, but that doesnt address its cause. If left untreated, it can cause ulcerations on the lip or prevent the dog from closing its mouth. It can also lead to periodontal disease.

It was having an impact on the breed because when you compete in conformation trials, the teeth are one of the things they look at, Clark said. You must have your canine tooth and it has to be pointing down otherwise, its a fault.

Dogs with lance canine can become pets, of course, but they are not shown.

If youre not shown, you are less likely to be bred, Clark said. These dogs are getting pulled from the breeding pool and youre losing genetic diversity over a crooked tooth.

Because the condition is rarely seen outside the Sheltie breed, Clark said she was sure it was heritable. Getting to its source would help breeders work toward eliminating it.

We took a genome-wide approach looking at genetic markers that span the entire genome hoping to find one or more of these markers associated with lance canine, she said.

This was no small task. Abrams began this study while she was still an undergraduate.

I started working on dental abnormalities in Shelties in 2017 as an undergraduate and received funding from the Clemson University Honors College, Abrams said. This enabled me to continue my research at a high level.

It took years to collect these samples, Clark added. Its slow and tedious to get enough samples to do these kinds of studies.

The dogs whose samples were used could not share common grandparents, so Abrams collected more than 200 samples and ultimately used 78 of those in genome-wide research.

This chart demonstrates that Shetland Sheepdogs with lance canines are significantly shorter and lighter than their counterparts.Image Credit: College of Science

I contacted owners from all over the world to collect the samples, said Abrams, who received her Bachelor of Science in genetics in 2019 before joining Clarks laboratory as a graduate student. I even got to present a portion of this work at a canine and feline genetics conference in Bern (Switzerland) in May 2019.

Abrams and Clarks efforts paid off in a surprising way.

We did find an association on chromosome 9, Clark said. In this region of the chromosome, there were about 30 genes. We generated sequence from a Sheltie with both canine teeth affected. We looked at those 30 genes for a variation that might have an effect. We found two variations in two different genes that looked like they could be problematic. One of the genes was growth hormone.

Because that gene is necessary for normal growth, Clark and Abrams went back to the study population and asked the owners to submit their dogs height and weight.

What we discovered is that dogs with lance canine are, on average, one inch shorter and six pounds lighter than unaffected Shetland Sheepdogs, Clark said.

And in a small breed that averages about 20 pounds and is 13 to 16 inches at the shoulder, this variation is significant.

Nobody had noticed before, Clark said.

But owners quickly had an aha moment as they made the connection.

Next, we looked at these two variations in the genomes of 224 other breeds and wild canids, Clark said. But they were only in toy breeds. They are all tiny dogs. The consequence of the growth hormone gene mutation is a mutant protein that is exactly the same as the one found in humans with pituitary dwarfism.

There is more work to be done, including exploration of why some canines are prone to missing teeth and what connection that might have to other health issues.

Missing teeth is interesting because it is in all breeds, but is more common in small breeds, Clark said. Dogs with two lance canines are significantly more likely to have missing teeth than a dog that has one lance canine. Theres some relationship there.

In addition to Abrams and Clark, other authors include Alexandra Hawks, Jacquelyn Evans and Jennifer Mason from the Clemson Universitys Department of Genetics and Biochemistry; Thomas Famula from the University of California, Davis; Mary Mahaffey from the University of Georgia; and Gary S. Johnson from the University of Missouri.

Abrams is supported by the Collie Health Foundation, and one of her latest projects is to study the genetics of epilepsy.

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National Academy of Sciences features undergraduate research that identifies new genetic factors contributing to small body size in dogs - Clemson...

Anita Qualls and Aditya Sood dont remember when they met.

Maybe it was during a group gathering in Myers Hall, where they both lived freshman year. It could have been in one of the many biology classes they shared. Regardless of the starting point, Qualls BS 19 and Sood BS 19 both agree that they became close friends while taking an evolutionary biology course their senior year.

So in the spring, when Qualls was looking for a way to support those fighting the COVID-19 pandemic, Sood was one the first people she contacted. The nonprofit they formed has helped ease the burden of thousands of frontline workers across the state. And at a time when collaboration is more important than ever, they are helping bring the UGA community closer together.

We were amazed at the interest from our friends to be involved, Qualls says. (Andrew Davis Tucker/UGA)

When the pandemic hit, Sood was in his second semester of medical school at Emory. Qualls was in Cambridge, England, as UGAs first-ever Churchill Scholar. The prestigious scholarship gave her the opportunity to study immunology before entering medical school at the University of California, San Francisco this fall.

After Qualls was forced to return to the States in mid-March, she actively sought ways to contribute to the fight against COVID-19. One of the friends she reached out to was Cali Callaway BS 17, MS 17, a third-year medical student at Cornell. She was involved in an effort to deliver restaurant-made meals to health care workers around New York, called NYP Healthcare Heroes.

The concept created a partnership between the organization and local restaurants who made and then delivered fresh meals to health care workers in hospitals and medical clinics around the state. To minimize touchpoints, Feed the Frontlines volunteers arent directly involved with food preparation or delivery. Instead, they handle the logistics of connecting with health care providers and providing funding to restaurant partners.

When Qualls, who was quarantining in Hiawassee but lives in Johns Creek, learned about Feed the Frontlines, she set up a similar effort in Athens. But she didnt want to stop there, so she contacted Sood, who lives in Alpharetta.

When the pandemic hit, Sood was in his second semester of medical school at Emory. (Andrew Davis Tucker/UGA)

We realized there was a need, not just with healthcare workers who were struggling but also with local restaurants that had no source of income but massive rents to pay. We realized we could join these two together, not just in Athens but across all of Georgia, Sood says.

What followed was a masterclass in networking and coordination. Qualls and Sood cast a wide net and reeled in dozens of friends and acquaintances from across Georgia who, like them, were trying to figure out a way to make an impact.

Feed the Frontlines Georgia grew from four people to 80 in just two and a half weeks, and it now serves more than 40 hospitals and clinics across the state. More than 1,000 meals are delivered statewide every week. Qualls estimates that 90% of the volunteers are current UGA students or alumni.

We were amazed at the interest from our friends to be involved, Qualls says. (A list of UGA alumni and students who work with Feed the Frontlines Georgia is listed below.)

Weve never worked on something that has been so fast paced and growing like this, she continues. Weve both run organizations before, and weve both been in leadership. But this was really unique because of the timeline and because of the eagerness of every person in our organization.

Feed the Frontlines Georgia serves not only cities like Athens, Atlanta, and Columbus, but it also provides crucial support to rural areas like Berrien County (east of Tifton) and Lanier County (near Valdosta).

To date, they have raised more than $75,000, which has kept dozens of restaurants afloat. Qualls and Sood say Feed the Frontlines Georgia will continue as long as there is a need, even after they return to school in the fall if necessary.

Feed the Frontlines Georgia AdministratorsAnita Qualls BS 19Aditya Sood BS 19Taylor Stumpf BS 20Jenny Zhang BS 20Vineet Raman BS 19, BA 19, BA 19Taylor Pigg, fourth-year student double-majoring in cellular biology and biologyElise Karinshak, second-year student double-majoring in data science and marketing

Feed the Frontlines Georgia CoordinatorsCristian Escalera BSEd 17Maya Ahmadieh BS 19, BA 19Prabhjot Minhas BS 19, BA 19Adrianne Smith BS 17, MPH 17Jessica Ma BA 20, BA 20Avni Ahuja BA 20Nidhi Thiruppathi BS 19Juhi Varshney BS 17, BA 17Jacob Greenway BS 19Landon Clark, fourth-year student majoring in biochemistry and molecular biologyJaaie Varshney, third-year student double majoring in political science and womens studiesJacob Struble, first-year student majoring in biochemistry and molecular biology

Feed the Frontlines Georgia VolunteersAnna McKenzie BA 18McKenzie Durand BS 20Aida Rassam BS 20Lizzie Digiovanni BMus 20Merritt Daniels BS 19Arnav Goyal, fourth-year student majoring in biochemistry and molecular biology

Read more here:
Anita Qualls and Aditya Wood: Feeding the Frontlines - University of Georgia

22-Sep-2020

Ingredients

An organic Swiss alpine rose extract for skin rejuvenation

Alpine Rose Active is a purified extract of organic alpine rose leaves, which rejuvenates the skin through the novel anti-aging concept of senolytics.

Alpine rose is one of the most typical and iconic Swiss alpine plants. It grows at high altitudes in acidic and nutrient- poor soils, and it has developed impressive strategies to protect itself against the attack by free radicals.

Due to the difficulty of cultivating the alpine rose, Mibelle Biochemistry collaborates with organic farmers in the Swiss Alps who harvest the precious leaves by sustainable wildcrafting.

Several in vitro and in vivo studies have shown that the activity of Alpine Rose Active:

Alpine Rose Active is therefore able to protect skin proteins against oxidative damage, a known cause of cellular senescence, as well as rejuvenate the skin through its senolytic activity when cellular senescence has already taken place. It is COSMOS approved* and ECOCERT certified**.

INCI (EU / PCPC) DeclarationRhododendron Ferrugineum Extract (and) Glycerin (and) Aqua / Water

Continued here:
Alpine rose active: Clearing zombie cells in the skin - Cosmetics Business

SOMERSET, N.J. (PRWEB) September 22, 2020

Catalent, the leading global provider of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, cell and gene therapies, and consumer health products, today announced that George Buchman, Ph.D., Vice President, Preclinical & Process Development, Catalent Cell & Gene Therapy, will present at the World Vaccine Congress, which will take place virtually on Sept. 28 October 1, 2020.

On Sept. 30 at 4:05 p.m. EST, Dr. Buchman will present Next-Generation Vaccines and Oncolytic Viruses: Current Challenges and Future Promise, giving an overview of the benefits and limitations of oncolytic viruses as immunotherapies. His presentation will discuss the manufacturing and analytical considerations, as well as a collaborative study that evaluates a new technology to assess transfection efficiency.

Dr. Buchman joined Catalent through its acquisition of Paragon Gene Therapy in 2019. He has more than 30 years of experience in the biotech industry, and has held roles at companies including Life Technologies (now Thermo Fisher), Celera Genomics and Gene Logic. Dr. Buchman obtained a bachelors degree in biochemistry from Albright College, Reading, Pennsylvania, and a doctorate in biochemistry from University of Maryland.

For more information, please visit https://biologics.catalent.com/events/world-vaccine-congress/.

About Catalent Cell & Gene TherapyWith deep experience in viral vector scale-up and production, Catalent Cell & Gene Therapy is a full-service partner for adeno-associated virus (AAV) and lentiviral vectors, and CAR-T immunotherapies. When it acquired MaSTherCell, Catalent added expertise in autologous and allogeneic cell therapy development and manufacturing to position it as a premier technology, development and manufacturing partner for innovators across the entire field of advanced biotherapeutics. Catalent has a global cell and gene therapy network of dedicated, large-scale clinical and commercial manufacturing facilities, and fill-finish and packaging capabilities located in both the U.S. and Europe. An experienced partner, Catalent Cell & Gene Therapy has worked with industry leaders across 70+ clinical and commercial programs. For more information, visit biologics.catalent.com/cell-gene-therapy/

About CatalentCatalent is the leading global provider of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, cell and gene therapies, and consumer health products. With over 85 years serving the industry, Catalent has proven expertise in bringing more customer products to market faster, enhancing product performance and ensuring reliable global clinical and commercial product supply. Catalent employs approximately 14,000 people, including around 2,400 scientists and technicians, at more than 45 facilities, and in fiscal year 2020 generated over $3 billion in annual revenue. Catalent is headquartered in Somerset, New Jersey. For more information, visit http://www.catalent.com

More products. Better treatments. Reliably supplied.

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Advantages of Oncolytic Viruses as Immunotherapies to be Discussed by Catalent Gene Therapy Expert at World Vaccine Congress - PR Web

Overview Of Itaconic Acid Industry 2020-2025:

This has brought along several changes in This report also covers the impact of COVID-19 on the global market.

The Itaconic Acid Market analysis summary by Reports Insights is a thorough study of the current trends leading to this vertical trend in various regions. Research summarizes important details related to market share, market size, applications, statistics and sales. In addition, this study emphasizes thorough competition analysis on market prospects, especially growth strategies that market experts claim.

Itaconic Acid Market competition by top manufacturers as follow: , Alpha Chemika, Chengdu Jinkai Biology Engineering, Itaconix Corporation, Jinan Huaming Biochemistry, Shandong Zhongshun Science & Technology Development, Spectrum Chemical, Zhejiang Guoguang Biochemistry, Nanjing Huajin Biologicals, Qingdao Langyatai Group, Qingdao Kehai Biochemistry, Ronas Chemicals, Shandong Kaison Biochemical,

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The global Itaconic Acid market has been segmented on the basis of technology, product type, application, distribution channel, end-user, and industry vertical, along with the geography, delivering valuable insights.

The Type Coverage in the Market are: SynthesisFermentation

Market Segment by Applications, covers:PlasticizerLubricating Oil AdditiveOthers

Market segment by Regions/Countries, this report coversNorth AmericaEuropeChinaRest of Asia PacificCentral & South AmericaMiddle East & Africa

Major factors covered in the report:

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Itaconic Acid Market Incredible Possibilities, Growth Analysis and Forecast To 2025 |Alpha Chemika, Chengdu Jinkai Biology Engineering, Itaconix...