Category Archives: Anti-Aging Medicine

Hyperbaric oxygen therapy can improve heart functionality in healthy aging humans.This, according to a new study by the Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center in Beer Yaakov.In this new study, director of the Sagol Center for Hyperbaric Medicine and Research at Shamir Medical Center Professor Shai Efrati and Dr. Marina Leitman, head of the Echocardiography Unit and Non-invasive Cardiology Service at Shamir Medical Center turned their attention to HBOTs impact on cardiac function.According to the center, the study of HBOT for cardiac function has been limited, mostly evaluating patients during and after short-term exposures. However, for the first time, the study was conducted in humans and it demonstrated that repetitive HBOT protocols have a sustained effect on heart function.Healthy patients receiving HBOT to improve cognitive function underwent a 60-session treatment course using the Sagol Centers regenerative HBOT protocols. Using a high-resolution echocardiography, patients were evaluated before HBOT was administered and three weeks after treatment concluded, to identify the sustained effect of the treatment. The study was conducted on 31 patients.Speaking to The Jerusalem Post, Efrati explained that hyperbaric oxygen therapy (HBOT) includes the inhalation of 100% oxygen at pressures exceeding one atmosphere absolute (ATA), which is the average atmospheric pressure exerted at sea level, in order to increase the amount of oxygen dissolved in the body tissues.Efrati, who has been pioneering new approaches for the application of HBOT treatments that specifically focus on HBOTs ability to trigger regeneration in the body, said that in the past HBOT has been applied worldwide mostly for chronic non-healing wounds. In recent years, there is growing evidence on the regenerative effects of HBOT, he said. We have now realized that the combined action of both hyperoxia (an excess of oxygen in the body) and hyperbaric pressure, leads to significant improvement in tissue oxygenation while targeting both oxygen and pressure sensitive genes, resulting in improved mitochondrial metabolism with anti-apoptotic (anti-cell death) and anti-inflammatory effects.According to Efrati, the newly developed protocols used in this study, which includes the intermittent increasing and decreasing of oxygen concentration, induces what is known as the Hyperoxic Hypoxic Paradox. This, he said induces stem cells proliferation and mobilization, leading to the generation of new blood vessels (angiogenesis) and tissue regeneration.Efrati said that during the first studies they conducted at the Sagol Center, they evaluated the beneficial effects of HBOT on brain injuries due to traumatic brain injury and stroke. However, in this study we evaluated for the first time the effect of these new regenerative HBOT protocols on the normal aging heart. For the first time in humans we have demonstrated that HBOT can improve cardiac function.Asked about what inspired the research, Efrati said that for over the last 12 years the team has developed an ongoing research program that investigates the regenerative effects of HBOT on different issues and degrees of damage. At the beginning we were focused on non-healing peripheral wounds, he said. Then, we turned our focus to certain types of brain injuries. However, once the researchers found that HBOT induced many of the essential elements crucial to repairing almost any mechanism, we initiated a complementary research program that targets other organs such as the heart and other elements related to expected age-related functional decline.Addressing the significance of this research, Efrati said that along with normal aging, there is typically a decrease in cardiac function particularly in the mitochondrial cells of the heart. The mitochondria are the powerhouse of the cell [and] this is where we create energy, he pointed out. HBOTs ability to improve mitochondrial function may explain the beneficial effects that we saw in the cardiac function of this normal aging population. By exposing the mitochondria to the fluctuations in oxygen by the use of HBOT, the team observed an improvement in contractility function of the heart meaning, the heart muscle contracted more efficiency over the course of the 60-session protocol. Efrati highlighted that the effect was particularly evident in the left ventricle, which is the chamber responsible for pumping oxygenated blood to the rest of the body. This is only the beginning of our understanding of the impact of HBOT on cardiac function in a normally aging population, and a larger and more diverse cohort will be required to further evaluate our initial findings, he said.Asked whether this treatment could also be used on people who are predisposed to heart conditions, Efrati said that the short answer is yes, but stressed that more research is needed.As far as we know, we are the first to identify HBOTs ability to improve cardiac function, he told the Post. Our study was on a group of 31 asymptomatic normal aging heart patients. We believe it is important to expand the scope of this study to a larger group, with both symptomatic and asymptomatic patients to understand the possibilities for HBOT as a treatment for patients with heart-related diseases, he emphasized.The Sagol Center has also been studying the impact of HBOT on a variety of cognitive conditions. We have also conducted studies which showed positive results for the treatment of post-concussion syndrome as a result of traumatic brain injury, post-stroke recovery, fibromyalgia, adding that today, medical professionals understand that fibromyalgia is linked to issues in the brain center responsible for pain interpretation. He made it clear that not every patient will benefit from HBOT, which is why patient selection should be done very carefully based on the damage seen in brain imaging assessments.For example, if someone has a stroke, some of the tissue at the core of the stroke will die we will not be able to recover this tissue, Efrati continued. But, other tissue that is damaged but not fully dead... is where HBOT can help. This damaged tissue, known as the metabolic dysfunction tissue (penumbra), is where we can have an impact and help recover lost function, he added.On the timeline as to when using HBOT protocols may be put into effect on healthy aging patients in Israel, Efrati said that these studies are already ongoing. I cant speak too much about this, as we are in the process of developing the results of the first study for publication, he said. However, we believe HBOT can positively impact both cognitive and physical performance in aging adults based on what we have seen at this point.Efrati said that they will continue pursuing this line of research as it has the ability to transform how we look at aging. Looking at 2020 and beyond, Efrati said that they have a number of research collaborations that are ongoing, including research on cognitive decline, fibromyalgia and PTSD. In addition, we have an ongoing research program on athletic performance both in professional and amateur level athletes, which looks at how HBOT may further improve performance, he said. Finally, we are studying the impact of HBOT on healthy aging adults to understand how HBOT may improve our health and cognitive performance as we age.Concluding, Efrati pointed out that when you look at aging as a disease that can be measured, then it can be treated, and this is a serious area of investigation for us.The study was led by Marina Leitman, MD; Shmuel Fuchs, MD; Amir Hadanny, MD; Zvi Vered, MD; and Efrati. It was published in The International Journal of Cardiovascular Imaging.

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Hyperbaric oxygen therapy improves heart function in healthy, aging people - The Jerusalem Post

There's something very voyeuristic aboutpeeking into someone's medicine cabinet, which is probably why it's become such an Instagram sensation. While I'd never openit upat a dinner party, if someone posts one on their feed for all the world to see, you can bet I'm zooming in. Being the medicine cabinet stalker that I am, I'm quite familiar with the products people fill them with, and some of the similarities are just impossible to miss.

You've probably noticed that, thanks to the popularity of Instagram,beauty products are far more aesthetically pleasing than they used to be. But the beauty of it is that what's inside is usually as effective as the bottle is chic. Thanks to my exhaustive research (I know, tough gig), I've rounded up the most popular medicine cabinet products on Instagram. Not only will they make your bathroom more photogenic, but they'll make you more photogenic. Shop the medicine cabinetworthy pics below.

Drunk Elephant's cult following is no joke, and nowhere is it more evident than among the medicine cabinets of Instagram. The ones that didn't feature any products from the brand were few and far between.

Drunk Elephant A-Passioni Retinol Cream ($74)

Retinol is an essential part of a skincare routine, and few new ones have gotten as much buzz as this one.

Embryolisse Lait-Crme Concentr ($16)

This French beauty find is a must for parched skin (on both the face and body).

Glossier Solution ($24)

Instagram-friendly, wallet-friendly, and skin-friendly.

Ouai Wave Spray ($26)

Simple packaging, simple to use. This wave spray gives all hair types subtle texture and body. (Plus, it smells amazing.)

Versed Hydration Station Booster With HA ($20)

There's a Versed serum for every skin concern. And at this price, you might as well just buy them all.

Versed Stroke of Brilliance Brightening Serum ($20)

It gets the job done (for way less money than other brightening serums on the market).

Vintner's Daughter Active Botanical Serum ($185)

Once you've tried this incredible potion, you'll never want to be without it.

Diptyque Paris en Fleur Candle ($74)

Empty Diptyque candle jars are the perfect size for a medicine cabinet and provide a very chic storage solution for brushes and other small products.

Supernal Cosmic Glow Oil ($108)

The new It face oil on the market has been popping up in medicine cabinet IGs (including my ownsee below).

Tatcha The Dewy Skin Cream ($68)

If you love Tatcha as much as I do, you need to try this dreamy lavender cream. It's been my go-to this winter.

Supergoop! Unseen Sunscreen SPF 40 ($34)

I don't need to tell you how important sun protection is, and this is how I and countless others choose to do it.

Herbivore Rose Hibiscus Hydrating Face Mist ($16)

This hydrating face mist is a bathroom (and airplane carry-on) staple.

Herbivore Blue Tansy Resurfacing Mask ($48)

It's no wonder Herbivore's chic, all-natural products havegarnered such a cult following. I saw as many of them as I did Drunk Elephant products (perhaps even more).

Glow Recipe Glass Skin Brightening Set ($57)

Every new Glow Recipe launch is met with high anticipation (and immediate medicine cabinet placement).

Summer Fridays Jet Lag Mask ($48)

If you travel a lot (or just want a boost of hydration and radiance), you need this popular mask.

Byredo Rose of No Man's Land Eau de Parfum ($180)

Byredo's line of unique, special fragrances in chic, minimal packaging is the go-to among the beauty (and fashion) crowd.

Dr. Barbara Strum Glow Drops ($145)

While Dr. Barbara Strum's linemight be a splurge, anyone who uses it will tell you how effective her products are.

Dr. Barbara Strum Darker Skin Tones Face Cream ($215)

This rich cream does wonders in the name of anti-aging.

Crme de la Mer Moisturizing Cream ($180)

Even though it's been around for ages,Crme de la Mer remains the holy-grail in luxury beauty and has plenty of devoted fans.

Sunday Riley Good Jeans All-In-One Lactic Acid Treatment (1.7 oz.) ($122)

If you want to look like you just got a facial, invest in this treatment. The exfoliating results are immediately visible.

Sunday Riley Travel Tidal Brightening Enzyme Water Cream ($22)

The water-based-cream craze pretty much started with this light and dewy gel-cream hybrid.

Next up, nine beauty products that make this 54-year-old look 10 years younger.

This article originally appeared on Who What Wear

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I Studied 47 Medicine Cabinet Instagrams, and These Products Were in 90% of Them - Yahoo Lifestyle

A drug designed entirely by artificial intelligence is about to enter clinical human trials for the first time. The drug, which is intended to treat obsessive-compulsive disorder, was discovered using AI systems from Oxford-based biotech company Exscientia. While it would usually take around four and a half years to get a drug to this stage of development, Exscientia says that by using the AI tools it's taken less than 12 months.

The drug, known as DSP-1181, was created by using algorithms to sift through potential compounds, checking them against a huge database of parameters, including a patient's genetic factors. Speaking to the BBC, Exscientia chief executive Professor Andrew Hopkins described the trials as a "key milestone in drug discovery" and noted that there are "billions" of decisions needed to find the right molecules for a drug, making their eventual creation a "huge decision." With AI, however, "the beauty of the algorithm is that they are agnostic, so can be applied to any disease."

We've already seen multiple examples of AI being used to diagnose illness and analyze patient data, so using it to engineer drug treatment is an obvious progression of its place in medicine. But the AI-created drugs do pose some pertinent questions. Will patients be comfortable taking medication designed by a machine? How will these drugs differ from those developed by humans alone? Who will make the rules for the use of AI in drug research? Hopkins and his team hope that these and myriad other questions will be explored in the trials, which will begin in March.

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AI-formulated medicine to be tested on humans for the first time - Yahoo Lifestyle

Last summer, David MacNeil's 7-year-old golden retriever Scout was diagnosed with cancer and given a month to live.

On Sunday, Scout was featured in a $6 million Super Bowl ad paid for by MacNeil raising cancer awareness and urging viewers to donate to the University of Wisconsin School of Veterinary Medicine that saved his life.

MacNeil, the CEO of WeatherTech which was featured in the ad paid for the spot that shone light on the schools program and research into fighting cancer in animals, according to NBC News.

Im alive thanks to a cutting edge program at the University of Wisconsins school of veterinary medicine, a voice representing Scout said in the ad. Their research has the potential to save millions of pets lives.

MacNeil told NBC News his story before the ad aired, explaining that he was willing to do whatever was needed to save Scout after he was given a one percent chance to live after doctors found a tumor on his heart.

There he was in this little room, standing in the corner, MacNeil told NBC News. ... And he's wagging his tail at me. I'm like, Im not putting that dog down. There's just absolutely no way.

Veterinarians treated Scout with aggressive chemotherapy and radiation the nearly eradicated the tumor, according to NBC News.

The programs dean Mark Markel told NBC News that their veterinary research also contributes to cancer-fighting efforts for humans.

So much of whats known globally today about how best to diagnose and treat devastating diseases such as cancer originated in veterinary medicine," Markel said.

Judging from the footage in the ad, Scout appears to now be happy and healthy. And a very good boy.

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CEO takes out $6M Super Bowl ad to thank veterinary clinic that saved his dog from cancer - Yahoo Lifestyle

Words by Kathy Michaels Photographs by Phil McLachlan

My life has been simple run fast, turn left, Dr. Andrew Dargie said over coffee one day in late fall, offering up one last thought on his work in the Okanagan and the path he took to get here.

It was an endearing understatement from someone who is clearly more comfortable with taking on big tasks than boasting about how he completed them. As a former All-American sprinter who earned a full-ride scholarship at Stanford University, speed is certainly one of the defining points of Andrews life. He competed for Team Canada numerous times, turning left over and over again as he rounded a track with some of the fastest people on the planet.

Simple, however, is where the sports metaphor falls apart.

For all his athletic abilities, academics were a priority for Andrew, who, after Stanford, obtained his medical doctor designation from the University of Calgary. In a newspaper article about him from that time in his life, a third dimension of his personality became clear. He is a compassionate individual. During medical school he found time to take on a meaningful volunteer commitment with the schools aboriginal health program. For this work he was awarded the Canadian Student Athlete Community Service Award.

His next step was entering vascular surgery residency in Manitoba.

Ultimately, he said, I realized that I loved acute care medicine, but I didnt love the operating room. So I transferred residency programs and obtained my CCFP designation and moved to the Okanagan.

Since arriving, hes worked as an emergency room physician at Penticton Regional Hospital as well as South Okanagan General Hospital. At the latter location, he is the department head of Emergency Medicine.

While in the Okanagan, Andrew took on another passion and is bringing to it the same focus and dedication he has for everything else. This passion is medical aesthetics. In addition to his ER work, he now practises advanced medical aesthetics in both Kelowna and Vernon.

I decided I love performing procedures and found something to help balance working in emergency, he said. Its personally satisfying. Im able to offer procedures that are a blend of art and science and people are appreciative and happy.

Its an interesting time in a rapidly expanding industry. Not so long ago, cosmetic surgery was the clear-cut facial rejuvenation strategy.

This can be a definitive solution to reduce the signs of aging, albeit an invasive, sometimes painful experience typically reserved for the socially elite and requiring significant down time for recovery.

Now, more people are seeking anti-aging services that are less invasive, have less down time and are more affordable. Just a few facial rejuvenation techniques that Andrew offers are botox, dysport, fillers and platelet-rich plasma injections. The clinics he works at offer lasers, CoolSculpting, microdermabrasions and chemical peels, amongst numerous other procedures and skin-care treatments.

While minimally invasive rejuvenation procedures are in high demand, the relative newness of the industry has created some issues and it is not as closely regulated as it perhaps should be. This was made plain in recent months as a non-medical civilian in the Vancouver area passed herself off as a doctor and injected dermal fillers into countless unwitting clients at a spa. She used an altered photocopy of a College Certificate of Licensure to convince medical suppliers that she had a medical licence and was certified to practise in British Columbia. In any other field of medicine it would sound ludicrous, but that it happened at all lays bare the fact that checks and balances are lacking.

Thats something Andrew worries about. And this is why he founded Aesthetics Training Canada, which offers the botox course and the filler course.

Ensuring medical professionals are properly trained is of the utmost importance. There are people injecting without any formal training in facial anatomy or rejuvenation. I said, how can I change this and provide a safe and standardized way for medical professionals to expand their scope of practice to include medical aesthetics? That was the impetus for offering these new comprehensive courses.

There are also clear gaps in proper medical care.

We have patients come in who have been getting procedures elsewhere for years, and when I go to take them through the consent process, they say, Wait, there are risks with these procedures? I was told there were zero risks, Andrew said. This shocks me. Thats not proper medicine and it really bothers me. Some people think about patients in terms of syringes or units. Or some prioritize how fast they can get a patient in and out of the door. This type of practice doesnt warn patients that there are, in fact, risks to consider.

To start creating the change he wants to see in the industry, each of Andrews treatment rooms has anatomy cards so he can take patients through what hes doing, what the risks are and how they can be mitigated.

There are all sorts of things we can do to optimize patient care, he said. If Im in emergency, whether its something as simple as cutting out a mole, or something more complicated like a cardioversion, we always take people through the risks and benefits, and it should be no different in medical aesthetics. Patients must consent and they must be educated that these are not completely harmless procedures and should be performed by experienced medical professionals only.

Adverse events can occur and these can be devastating, Andrew said. The results of shoddy, haphazardly conducted work can be disfiguring or worse even blinding and he wants to prevent this.

He also wants to bring back a more natural look.

People that come to see me get full transparency, and a natural look, he said.

The day before the interview, Andrew said he had turned away four patients who had come in seeking lip filler treatment.

Hed told them, I think your lips are already full enough and we want you to look natural.

They may go down the street and get that duck lip. But our patients arent getting that. Theyre going to get an honest and fair assessment and can expect a refreshed, natural look.

Interestingly, the four who were turned away were receptive to feedback and appreciated hearing his honest and clear communication.

Andrew has accomplished a lot in his life and is bound to take on more. What makes him different than others, however, is that he makes things look easy. He has a light and pleasant demeanour that puts people speaking to him at ease. If you didnt know better, it would be possible to believe that he did have a simple life, remarkable only by his ability to go fast and turn left.

More info at http://www.drdargie.com

Story courtesy of Boulevard Magazine, a Black Press Media publication

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Combining art and science in a medical practice - Coast Mountain News

LOS ANGELES From face lifts to tummy tucks, there are plenty of options for people looking to take advantage of surgery in order to look better or appear younger. Now, a new study conducted at the University of California, Los Angeles says that a rhinoplasty, more commonly referred to as a nose job, can help women appear up to three years younger.

While the subject of youthful appearance and beauty is often a subjective matter, researchers took a novel approach to come to their conclusions: machine learning facilitated by artificial intelligence. This advanced technology was used to analyze the before and after images of 100 female rhinoplasty patients of varying ages (16-72). All of the analyzed women had undergone a nose job for cosmetic reasons by the same UCLA surgeon who led this study, Dr. Robert Dorfman.

After at least 12 weeks post-op, the womens pictures were analyzed by computers. The AI then estimated each womans age by cropping their face from the image and then running it through a complex algorithm.

Rhinoplasty is widely recognized as a facial beautification procedure, but it isnt commonly known for its anti-aging effects, comments Dr. Dorfmana, a resident physician in the division of plastic and reconstructive surgery at the David Geffen School of Medicine at UCLA, in a release.

A typical rhinoplasty entails structural changes to face bones and nose cartilage achieved via small incisions made by surgeons while the patient is under anesthesia. Of course, each procedure is specially implemented to the patients individual face, features, and desires for the surgerys outcome.

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This is the first time that scientific evidence has emerged that a nose job can help a woman appear younger; most people opt for a rhinoplasty because they are unhappy with the general appearance of their nose, or due a to a facial injury.

This technology allows us to accurately estimate age in an objective way and has proven to recognize patterns and features of aging beyond what the human eye can perceive, Dr. Dorfman says.

The rejuvenating effects were most prominent among women over the age of 40, with the computer estimating that some older women appeared up to seven years younger following their surgery. That being said, only 25 women over the age of 40 were included in the study, so researchers stress that additional work must be done to confirm these findings.

The nose loses support as it ages and can take on a more prominent or droopy appearance, comments Dr. Jason Roostaeian, a senior author on the study. When we lose facial fat and volume in our cheeks, which are the canvas that our nose sits on, the nose becomes more prominent.

Dr. Roostaeian went on to say that tweaking the appearance of the nose can help ones entire face appear younger. This is something we have subjectively thought for many decades but now we have objective evidence through artificial intelligence to support this.

The study is published in the Aesthetic Surgery Journal.

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More Than Looks: Getting A Nose Job Takes Years Off A Womans Face Too, Study Finds - Study Finds