Category Archives: Anti-Aging Medicine

Posted on March 24, 2017, 6 a.m. in Cancer Exercise

New study reveals that lactate, a molecule produced during intense exercise, plays a key role in cancer cell formation.

Medical researchers are on a quest to develop a comprehensive understanding of the mechanism that causes the process in which cells become cancerous. This process is known as oncogenesis. A recent study keys in on the molecule generated amidst intense exercise known as lactate. The purpose of this research is to explain lactate's role in the creation of cancer cells. The latest study's findings were published in the popular journal Carcinogenesis. About Lactate

Lactate is the byproduct of glycolysis, a chemical process that breaks apart sugar into smaller molecular components with the ultimate aim of generating energy. Lactate builds up in the blood and tissues when one engages in intense physical activity. If enough lactate accumulates, it can cause diminished physical performance as well as muscle tightness.

A famous German scientist named Otto Warburg first noticed that cancer cells consume an abundance of glucose compared to regular cells. Known as the Warburg effect, this phenomenon is a reference to the fact that cancer cells proceed through more glycolysis and generate more lactate than regular cells. The Latest Research

New research on this subject matter has been spearheaded by the director of the Sports Performance Department and physiology laboratory at the University of Colorado-Boulder's Sports Medicine and Performance Center. The director, Inigo San Millan, was determined to figure out why the Warburg effect occurs. Cancer research has deviated from cell metabolism study to genetics since Warburg's heyday in the early 20th century. However, the latest research might shift the spotlight back to lactate's role in the context of cancer development. Lactate and Oncogenesis

San Millan's research team suggests that lactate is the sole metabolic compound necessary and involved in the nearly half-dozen stages that stem from carcinogenesis. Their study analyzed the role of lactate in the process through which new blood vessels develop within tumors. This medical term for this process is angiogenesis. The study also examined the role of lactate in immune escape. This term refers to the cancer cells' eluding of the human body's natural immune responses. It also delves into the role of lactate in cell migration, self-sufficient metabolism, and metastasis.

San Millan's paper details how lactate assists in the creation of an acidic microenvironment outside of the cancer cell during metastasis. This phenomenon triggers the spread of additional cancer cells. The study also explores the connection between genetic components and lactate. The research team hypothesized that three transcription factors (p53, cMYC and HIF-1) common in the majority of cancers catalyze the deregulation of lactate. Can Halting Lactate Stop Cancer?

The important role of lactate in cancer cell creation helps explain why people who exercise on a regular basis have a low risk of cancer development. Individuals who exercise enjoy a body that is trained to transfer lactate to an energy source for the body, preventing an excessive accumulation of the metabolic compound. The findings allow for speculation that an idle lifestyle combined with an excessive consumption of sugar might lead to an abundance of lactate that leads to cancer. These findings show that lactate is not only present when cancer develops but required for each step of its development. What's Next?

San Millan hopes to team up with the University of Colorado Hospital to analyze the effects of custom tailored physical fitness programs created for cancer patients. At the moment, San Millan is studying the nuances of breast cancer cell lines. His hope is that additional research will ameliorate the quest to develop drugs that prevent the accumulation of lactate. These drugs will likely help key in on monocarboxylate transporters that transmit lactate between the body's cells.

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Lactate May Drive Cancer Development - Anti Aging News

Posted on March 23, 2017, 6 a.m. in Depression Alternative Medicine Exercise

Study finds that yoga classes accompanied by home practice lead to a significant reduction in symptoms of depression.

Depression is a mental health condition that affects the brain and often begins in early adulthood. According to the Anxiety and Depression Association, more than 15 million Americans were identified as suffering from depression in 2016. Although anyone at any age may suffer from depression, its more common in women.

Depression is recognized as a distinct condition and treatments range from drugs to psychotherapy, to lifestyle choices. Most antidepressant drugs work to change the chemical reactions occurring in the brain. While the drugs each work in a slightly different way, they are each intended to balance neurotransmitters. Many people are successfully treated with these drugs.

Unfortunately, however, not all drugs work. Some individuals experience side effects, while others simply dont want to take drugs, and some dont find any relief from their symptoms. Doctors and researchers have worked for years to find alternative ways to treat depression. Diet, exercise, counseling, and supplements are some of the alternatives being explored. Another alternative is yoga.

In a recent study reported in the Journal of Alternative and Complementary Medicine, individuals who participated in yoga classes at least twice a week and practiced additionally at home, experienced a decrease in their symptoms. Specifically, this study used lyengar yoga which is a practice that works to improve strength, mobility and balance. Particular attention is given to breath control known as pranayama. The poses or asanas used during practice all work to accomplish the lyengar goals.

Participants in the study were broken into two groups. One group participated in 90-minute yoga classes three times a week, while the other group practiced 90 minutes twice a week. Both groups were advised to additionally practice at home. Each group contained clients who were taking prescription antidepressants as well as those who did not. At the end of the study, both groups reported an overall decrease in symptoms. This held true for those who were on antidepressants as well as those who were not.

While drug therapy may be a viable option for some, a yoga alternative seems to offer substantial relief to individuals suffering from depression without to risk of side effects or harmful drug interactions. The good news for people suffering from depression is that yoga offers them an additional choice about treatment.

Chris C. Streeter, Patricia L. Gerbarg, Theodore H. Whitfield, Liz Owen, Jennifer Johnston, Marisa M. Silveri, Marysia Gensler, Carol L. Faulkner, Cathy Mann, Mary Wixted, Anne Marie Hernon, Maren B. Nyer, E. Richard P. Brown, John E. Jensen. Treatment of Major Depressive Disorder with Iyengar Yoga and Coherent Breathing: A Randomized Controlled Dosing Study. The Journal of Alternative and Complementary Medicine, 2017; DOI: 10.1089/acm.2016.0140

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Yoga for the Blues - Anti Aging News

Fill your plate with the following kinds of foods and you might hike your risk of heart disease, cancer, and a variety of other serious illnesses. Avoid or limit:

Charred meat: Studies have found that grilled or well-done meat creates compounds that have been linked to an increased risk of colon, pancreatic, stomach, and possibly other cancers.

Processed meats: Though red meat in general has been associated with an increased risk of colon cancer, salami, pepperoni, ham, and other cured meats may predispose you to esophageal, kidney, stomach, and prostate cancer.

Refined carbohydrates: Diets that are high in added sugars (candy, some cereals, pastries, sodas) and carbohydrates that have been stripped of many of their important nutrients (these are carbs such as white flour and white rice) may shorten telomeres and hike the risk of type 2 diabetes, obesity, heart disease, and stroke, especially in those who are overweight.

Prepackaged meals: These food products may be convenient but they're often extremely high in sodium. That has been linked to a higher risk of hypertension, cardiovascular disease, and kidney disease.

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6 Anti-Aging Foods You Should Try - ConsumerReports.org

Dr. Shallenberger is a six time grandfather and four time father. He is one of the originals. He has been practicing medicine since 1973 and has been a pioneer in alternative/integrative medicine since 1978. He is one of only 16 physicians in Nevada that are licensed both in conventional medicine as well as alternative and homeopathic medicine. This allows him to integrate the best of both approaches for optimal results.

Dr. Shallenberger has revolutionized the practice of anti-aging and preventive medicine by developing a method to measure mitochondrial function and oxygen utilization. He has written two popular books describing this method, The Type 2 Diabetes Breakthrough and Bursting With Energy, and has authored numerous papers in the international peer reviewed literature on ozone therapy and oxygen utilization. He is also the editor of Second Opinion alternative medical newsletter.

He is the developer of Prolozone, an injection technique that has been shown to regenerate damaged joints, herniated discs, and degenerated joints, tendons, and soft tissues. He has just published the first paper on Prolozone Therapy in the Journal of Prolotherapy entitled, Prolozone Regenerating Joints and Eliminating Pain.

Examiners.

Dr. Shallenberger has published several scientific and clinical papers, and has lectured extensively in the United States and abroad. He is best known for his research involving the use of ozone therapy for immune related disorders.

Dr. Shallenberger and the entire staff at The Nevada Center of Alternative and Anti-Aging Medicine are committed to providing you with the best and latest in biological and medical diagnosis and therapy. Additionally, we will supply you with all the information and support your need to get well in a sensitive and unhurried manner.

Click here for Dr. Shallenbergers Second Opinion Newsletter and Health Alerts

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Anti Aging Treatment | Alternative Medicine | Dr. Frank ...

Thuy Truong thought her aching back was just a pulled muscle from working out. But then came a high fever that wouldn't go away during a visit to Vietnam. When a friend insisted Truong, 30, go to an emergency room, doctors told her the last thing she expected to hear: She had lung cancer. Back in Los Angeles, Truong learned the cancer was at stage 4 and she had about eight months to live.

"My whole world was flipped upside down," says Truong, who had been splitting her time between the San Francisco Bay Area and Asia for a new project after selling her startup. "I've been a successful entrepreneur, but I'm not married. I don't have kids yet. [The diagnosis] was devastating."

Doctors at the University of Southern California took a blood sample for genetic testing. The "liquid biopsy" was able to detect tumor cells in her blood, sparing her the risky procedure of collecting cells in her lungs.

Genetic sequencing allowed the lab to isolate the mutation that caused her cancer to produce too much of the EGFR (epidermal growth factor receptor) protein, triggering cancer cells to grow and proliferate. Fortunately, her type of mutation responds to EGFR-targeting drugs, such as Tarceva or Iressa, slowing tumor growth.

Personalized medicine uses genetic information to design treatments targeted to individual patients.

Unlike chemotherapy, which blasts all fast-growing cells in its wake, targeted treatments go after specific molecules. That makes them more effective at fighting particular types of cancers, including breast, colorectal and lung cancers. Now the approach is being expanded to fight an even broader range of cancers. It's all part of a new wave in health care called personalized, or precision, medicine.

"This is the future of medicine," says Dr. Massimo Cristofanilli, associate director for translational research and precision medicine at Northwestern University. "There is no turning back. The technology is available and there are already so many targeted therapies."

Most medical treatments have been designed for the average patient, leading to a one-size-fits-all approach. But with vast amounts of data at their disposal, researchers now can analyze information about our genes, our family histories and other health conditions to better understand which types of treatments work best for which segments of the population.

This is a big deal. But it requires the know-how of geneticists, biologists, experts in artificial intelligence and computer scientists who understand big-data analytics. Several startups have already begun this work.

Deep Genomics, founded by researchers at the University of Toronto, uses AI to predict how genetic mutations will change our cells and the impact those changes will have on the human body. Epinomics, co-founded by scientists and physicians from Stanford University, is building a map of what turns our genes on and off, giving physicians a guide they could use to craft personalized therapies. And Vitagene, a small San Francisco startup, provides personalized advice on nutrition and wellness based on your DNA.

Dr. Massimo Cristofanilli

Just like Facebook learns to automatically recognize Aunt Martha in your family photos, Deep Genomics finds and categorizes patterns in genetic data. Once it's found those patterns, the company's deep learning system can infer if and how changes to your DNA affect your body.

That's a big step forward compared with current genetic tests. Most can only give a probability of, say, getting breast cancer based on data from an entire population. Other tests can't even tell you if the genetic changes they've detected mean anything.

The work is personal for Brendan Frey, CEO and co-founder of Deep Genomics and a professor at the University of Toronto. Fourteen years ago, he and his wife discovered their unborn baby had a genetic condition.

"We knew there was a genetic problem, but our counselor couldn't tell us if it was serious or if it was going to turn out to be nothing," Frey says. "We were plunged into this very difficult, emotional situation."

The experience made Frey want to bridge the divide between identifying genetic anomalies and understanding what they mean.

Deep learning or machine learning -- when computers teach themselves as they see more data -- can also help doctors know which drugs will most effectively treat a patient's illness and whether that person is more likely to experience side effects.

It can also help predict how cancer cells will mutate. And that can help drug companies come up with new treatments as tumor cells change and patients no longer respond to the drugs that worked.

That could help turn a disease like cancer into a manageable chronic ailment, says Cristofanilli.

Where Deep Genomics analyzes patterns in genetic data to predict when mutations will make you sick, Epinomics looks at epigenomics, or the study of what turns our genes on and off.

The company describes it like this: If your genome, which shows what genes we have, is the hardware of our bodies, then the epigenome is its software programming. Epinomics aims to decode that programming.

Every cell in the body carries the same genetic code. But cells in the heart, brain, bone and skin function differently based on this programming. It happens because chemical markers attach to DNA to activate or silence genes. These markers, known as the epigenome, vary from one cell type to another and are affected by both nature (inheritance) and nurture, which can include the air we breathe and the food we eat.

Researchers think a disruption to the epigenome can cause illnesses such as Alzheimer's disease, diabetes or cancer. Understanding it could give physicians a guide to the best options for each patient, like having a GPS for treatments at the molecular level.

"We are focusing on what is happening at the programming level of each cell," says Epinomics co-founder Fergus Chan. "Once we understand how genes are being turned on and off, we'll be able to better predict which treatments will work or whether changes to lifestyle will have an impact on health."

When Vitagene co-founder and CEO Mehdi Maghsoodnia asked a doctor what vitamins he should be taking, he was handed a bottle of pills and told to hope for the best.

Fergus Chan

That was the beginning of Vitagene, which uses genetic data and other health information culled from a detailed questionnaire to deliver a personalized nutritional supplement plan that lists which vitamins you need and in what doses, as well as what to avoid.

Maghsoodnia offers an alternative to the one-size-fits-all $27 billion US dietary supplement industry. Customers pay $99 to have their DNA tested and blood analyzed. And for $69 a month, Vitagene will package and ship supplements in dosages tailored to your individual needs.

The Food and Drug Administration estimates there are more than 85,000 dietary supplements on the US market, most of which are unregulated. Nearly all are "promising everything from anti-aging to weight loss, and no science behind it to tell you what works for you," says Maghsoodnia. "We help filter through the noise."

Vitagene's algorithm has been tested on patients who've had bariatric surgery for weight loss, which often leaves them deprived of key nutrients. Vitagene helped develop a supplement regimen to get these patients the nutrition they need after surgery.

Precision medicine is in its early days.

This is especially true for psychiatry and its exploration of how the brain responds to the environment, stress and genetic disorders. Now several companies are selling tests to help psychiatrists select drug treatments by looking at patients' DNA mutations and their metabolizing rate.

See more from CNET Magazine.

But critics caution that these genetic tests may be overselling their capabilities.

"Precision medicine has been very promising in oncology," says Jose de Leon, a professor of psychiatry at the University of Kentucky who specializes in psychopharmacology. "But we know a lot more about cancer and how it works. In psychiatry, it's much harder because we don't know enough about how the brain works."

Yes, precision medicine holds enormous promise.

Even so, Northwestern's Cristofanilli cautions clinicians to stay grounded in reality. "It can be difficult to understand where reality becomes imagination," he says. "We want to make sure we are protecting patients from claims that we may not deliver."

For her part, Truong is grateful to benefit from the work that's already been done. "I'm an engineer," she says.

"I don't believe in miracles. I believe in science."

This story appears in the spring 2017 edition of CNET Magazine. For other magazine stories, click here.

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Gene therapy: What personalized medicine means for you - CNET

Rx Medical Web is going to help our clients grow their business and increase revenue because they will be advertising their new services to patients.

Fort Lauderdale, FL (PRWEB) March 21, 2017

One of Empire Medical Trainings goals is to help their students learn more about how to create new revenue streams in their practice. Empire Medical Training provides a wide variety of courses that show participants how to implement proper techniques and procedures in services like aesthetics, pain management, and weight loss. With these added services members have learned, the next step for the members includes building a website and marketing their business.

Rx Medical Web is able to provide Empire Medical Training attendees with a one-on-one consultation at any of the seminars and workshops in regards to building a new website and beginning to market their practice online. Each member will now have the chance to meet with an expert marketing advisor to develop a personalized and effective business-marketing plan. As Dr. Stephen Cosentino, President and Founder of Empire Medical Training, states, Rx Medical Web is going to help our clients grow their business and increase revenue because they will be advertising their new services to patients. In addition, with Rx Medical Web working solely for Empire Medical Training, we are able to offer our members a discounted rate on their marketing and website efforts.

Empire Medical Training has worked with Rx Medical Web over the years and is impressed with the testimonials and compliments from customers. Before the acquisition, Rx Medical Web had limited availability to work with members attending the Empire Medical Training workshops. This acquisition has been in the works for over two years and has helped the vision of providing full-time services to Empire Medical Training clients come to fruition.

Rx Medical Web was founded in 2008 and has been building websites and creating marketing plans for physicians and other healthcare professionals ever since. Rx Medical Web specializes in the niche group of medical practices to help them expand their businesses. With Stephen Cosentino as their President, he is able to provide practices with proper content for their medical sites as well as email marketing campaigns.

Empire Medical Training has been training Physicians and Health Care Practitioners since 1998, longer than any other procedural training institution. With over 45,000 graduates in specialties such as Aesthetics, Anti Aging/Weight Management Medicine, and Pain Management, Empire Medical Training is renowned throughout the United States and abroad as the premier academy for providing academic excellence. Dr. Stephen Cosentino pioneered ways to add new procedures and services as well as business strategies to a practice and improve patient care. With Dr. Cosentinos commitment and dedication to the specialty and the field of medicine, Empire Medical Training is steadfast to developing new training programs and topics to broaden the scope of the primary care practitioner. All Empire courses are created through mainstream medicine using the most current technologies and standards of care.

For more information on Empire Medical Training, please visit their website or call 866-366-1576.

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Empire Medical Training Acquires Rx Medical Web - PR Web (press release)