NEW YORK, Feb. 16, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:
Future US Nucleic Acid Testing Market Outlook
Highlights
Comprehensive 880-page market segmentation analysis of the US NAT market. Major issues pertaining to the US NAT laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next ten years. An extensive review of DNA probe and biochip technologies, test formats, detection methodologies, trends in testing automation and amplification methods. Ten-year test volume and reagent sales forecasts for the following categories:
- Infectious Diseases
- Cancer
- Forensic Testing
- Genetic Diseases
- Paternity Testing/HLA Typing
Review of testing methodologies and instrumentation technologies. Feature comparison of automated and semiautomated analyzers. Sales and market shares of leading suppliers. Over 60 specific opportunities for NAT instruments, test systems, IT and auxiliary products. Profiles of major suppliers, and emerging market entrants, including their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies. Alternative market penetration strategies. Potential market entry barriers and risks. Business planning issues and concerns.
Contains 880 pages and 37 tables
Table of ContentsIntroduction
Worldwide Market And Technology Overview
A. DNA Sequencing
1. Introduction
2. Sequencing Methods
3. Autoradiography
4. The Human Genome Project
5. Sequencing Automation
6. Image Scanners
7. Fluorescent Detection
8. Gene Profiling
9. Gene Expression
10. Polymorphism Screening
11. Protein Interaction Networks
B. DNA And RNA Probe Technology
1. Basic Principles
2. Probe Preparation
3. The DNA Probe Test
a. Sample Preparation
b. Hybridization
c. Separation
d. Detection/Measurement
4. Test Formats
a. Filter Hybridization
b. Southern Blot
c. Northern Blot
d. In Situ Hybridization
e. Others
5. Labeling Techniques
6. Amplification Methods
O Polymerase Chain Reaction
- Temperature Cyclers
- PCR Variations* Immuno-PCR* QC-PCR* DAP-PCRO Strand Displacement ActivationO TMAO Ligase Chain ReactionO Branched DNA- Hybridization Protection AssayO Nucleic-Acid Sequence-Based AmplificationO Self-Sustained Sequence ReplicaseO Others- Ampliprobe- CAR- CAS- CPT- Dendritic Polymer Technology- ISO-CR- LAT- Probe Networks- RAMP- Repair Chain Reaction- Rolling Circles- Sequence Independent Gene Amplification- Sequence Initiation Reaction- SISPA- Solid Phase AmplificationC. Detection Technologies1. Radioactive Methodsa. Overviewb. Major IsotopesO P-32O S-35O H-3O I-1252. Non-Isotopic Methodsa. Enzymatic Labelsb. Chemical LabelingO Indirect Chemical LabelingO Direct Chemical Labeling
c. Fluorescence
d. Chemiluminescence
e. Electrical Conductivity
D. Instrumentation Review
1. Abbott LCx
2. Beckman Coulter/Biomek FK
3. Becton Dickinson SDA
4. Bio-Rad GeneScope
5. Gen-Probe Tigris
6. Roche Cobas Amplicor
7. Tecan LS Series
E. Biochips: Genosensors, Microarrays, and
Labs-on-the-Chip
- Liquid Transportation and Mixing
- Separation
- Reaction
- Detection
F. Pharmacogenomics
G. Major Applications
1. Microbiology/Infectious Diseases
a. Overview
b. Major Infectious Diseases
* AIDS
O Structure and Composition
O Classification
O AIDS Origins
O Animal Lentivirus Systems
O Virus Receptors
O HIV Infections in Humans
- Pathogenesis and Pathology
O CD4T Lymphocytes and Memory Cells
O Monocytes and Macrophages
O Lymphoid Organs
O Neural Cells
O Viral Coinfections
- Clinical Findings
O Plasma Viral Load
O Pediatric AIDS- Neurologic Disease- Opportunistic Infections- CancerO Immunity- Virus Isolation- Serology- Viral Nucleic Acid/Antigen DetectionO Epidemiology- Worldwide Spread of AIDS- United States- Routes of TransmissionO DNA Probes- Overview- Quantitative PCR- In Situ PCR- Needed ImprovementsO Viral Load/Drug Resistance TestingO Genotype and Phenotype TestingO Blood Banking Considerations* AdenovirusO BackgroundO Diagnostic TestsO Vaccines and DrugsO Adeno-Associated Viruses (AAV)* Anthrax/Bacillus AnthracisO BackgroundO Diagnostic TestsO Vaccines and Drugs* BabesiosisO Background* BEA and Other Bartonella DiseasesO BackgroundO Diagnostic TestsO Vaccines and Drugs* Chagas DiseaseO Background
* Campylobacter
O Background
O Diagnostic Tests
- Culture Identification
O Vaccines and Drugs
* Chlamydia
O Background
- Chlamydia psittaci
- Chlmaydia pneumoniae
- Chlamydia trachomatis
O Diagnostic Tests
O Vaccines and Drugs
* Creutzfeldt-Jakob's Disease
O Background
O Blood Transmission
O Diagnostic Tests
O Major Commercial and Academic Players
- Bayer
- Disease Sciences/Bio Tec Global
- Imperial College School of Medicine
- Ortho-Clinical Diagnostics
- Pall
- ProMetic Life Sciences
- Proteome Sciences/Idexx
- Q-One Biotech
- Serono
- U.S. Agricultural Research Service
O Drugs
O Vaccines
* Cytomegalovirus
O Background
- Chorioretinitis
- Gastrointestinal
- Central Nervous System Disease
O Diagnostic Tests
O Vaccines and Drugs
* Ebola Virus
O Background
- Epidemiology
- Clinical Syndromes
O Diagnostic TestsO Vaccines and Drugs* EchoVirusO Background- Acute Aseptic Meningitisis- Encephalitis- Exanthems- Respiratory Disease- Myopericarditis- Neonatal InfectionsO Diagnostic TestsO Vaccines and Drugs* EncephalitisO BackgroundO Diagnostic TestsO Vaccines and Drugs* EnterovirusesO BackgroundO Diagnostic Tests- Viral Isolation and Identification- Antibody TestsO Vaccines and Drugs* Epstein-Barr VirusO BackgroundO Diagnostic TestsO Vaccines and Drugs* GonorrheaO BackgroundO Diagnostic TestsO Vaccines and Drugs* HepatitisO Hepatitis AO Hepatitis B- Structure and Composition- ReplicationO Hepatitis CO Hepatitis D (Delta)O Hepatitis EO Hepatitis GO Hepatitis Infections PathologyO Clinical FindingsO Laboratory Tests
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D
- Hepatitis E
O Virus-Host Immune Reactions
O Epidemiology
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D (Delta)
O Vaccines and Drugs
* Herpes Simplex Virus
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Legionella
O Background
O Diagnostic Tests
O Vaccines and Drugs
* Lyme Disease
O Background
- Clinical Description
- Clinical Case Definition
- Laboratory Criteria for Diagnosis
- Case Classification
O Diagnostic Tests
O Vaccines and Drugs
* Malaria
* Mycoplasma
O Background
- Ureaplasma Urealyticum & Mycoplasma
Hominis
O Diagnostic Tests
O Vaccines and Drugs
* Papillomaviruses/HPV
O Background
- HPV in Cancer
- Cervical Neoplasm
O Diagnostic Tests
O Vaccines and Drugs
- Prevention* Parvovirus B19O Background- Microbiology- Epidemiology- Clinical Syndromes- Erythema Infectiosum (Slapped Cheek)- Adult Polyarthropathy- Transient Aplastic Crisis- Transient Pancytopenia- Red Cell Aplasia in Immunocompromised- Perinatal InfectionsO Diagnostic TestO Vaccines and Drugs* PneumoniaO BackgroundO Diagnostic TestsO Vaccines and Drugs* PolyomavirusesO BackgroundO Diagnostic TestsO Vaccines and Drugs* SalmonellosisO BackgroundO Diagnostic TestsO Vaccines and Drugs* ShigellosisO BackgroundO Diagnostic TestsO Vaccines and Drugs* StreptococciO BackgroundO Diagnostic TestsO Vaccines and Drugs- Group A Streptococci- Group B Streptococci* ToxoplasmosisO BackgroundO Diagnostic TestsO Vaccines and Drugs
* Tuberculosis
O Background
O Diagnostic Tests
- Microscopic Characteristics
- Cultural Characteristics
- Skin Tests
- MDRTB
O Vaccines and Drugs
* West Nile Virus
O Background
- Clinical Syndromes
O Diagnostic Tests
O Vaccines and Drugs
* Yersinia
O Background
O Diagnostic Tests
O Vaccines and Drugs
c. Antibiotic Susceptibility
2. Cancer Testing
a. Overview
b. Major Cancer Types
* Prostate
* Lung
* Colon and Rectum
* Breast
* Skin
* Uterine
* Leukemia
* Oral
c. Oncogenes
O Abl/abl-bcr
O AIB1
O BCL-2
O BRCA1
O CD44
O C-fos
O C-myb
O C-myc
O CYP17
O Erb-B
O HPC1
O N-mycO P40O P51O P53O PIK3CAO PTI-1O RasO RegO SisO Src3. Genetic Diseasesa. Overviewb. Nucleic Acid Amplificationc. Chromosome Imagingd. Genomics Technologiese. Proteomics Technologiesf. Current Pharmacogenomic Testsg. Future Pharmacogenomic Testingh. Major Diseases* Achondroplasia* Autosomal Dominant Polycystic KidneyDisease* Cancer* Cosmetogenomics* Cystic Fibrosis* Down's Syndrome* Duchenne and Becker Muscular Dystrophy* Factor V (Leiden)* Factor IX Deficiency* Fragile X Syndrome* Heart Disease* Hemochomatosis* Hemophilia* Huntington's Disease* Maternal-Fetal Incompatibility* Multiple Endocrine Neoplasia* Phenylketonuria (PKU)* Polycystic Kidney Disease (PKD)* Prenatal Screening* Retinitis Pigmentosa* Retinoblastoma* Sickle Cell Anemia
* Spinal Muscular Atrophy
* Vitamin B12 Metabolism
i. Social Issues and Concerns
4. Forensic Testing
a. Overview
b. Multilocus and Single Locus Probes
* Multilocus Probes
* Single Locus Probes
* PCR and RFLP
c. The FBI
d. DNA Profile Data Banks
* U.S.A.
* U.K.
e. Judicial Implementation
f. Major Crime Categories
g. Factors Contributing to the DNA Probe
Market Expansion
* Technology Availability
* Use of Hair as Evidence
h. Wildlife Forensics
5. Paternity Testing/HLA Typing
6. Other Applications
a. Disease Susceptibility Testing
b. Cardiovascular Diseases
c. Diabetes
d. Alzheimer's Disease
e. Periodontal Disease
f. Plasma Purification
g. Organ Transplantation
h. Water Contamination
i. Other
H. Competing/complementing Technologies
1. Monoclonal Antibodies/Immunoassays
2. RNA Probes
3. Two-Dimensional Electrophoresis
4. Flow Cytometry
I. Worldwide Market Overview
1. Business Environment
2. Market Structure
3. Market Size and Growth
USAA. Executive SummaryB. Business EnvironmentC. Market StructureD. Market Size, Growth And Major Suppliers'Sales And Market SharesMajor Product Development OpportunitiesA. InstrumentationB. Reagent Kits and Test Systems/panelsC. Computers, Software and AutomationD. Auxiliary ProductsDesign Criteria For Decentralized Testing ProductsAlternative Market Penetration StrategiesA. Internal DevelopmentB. Collaborative ArrangementsC. University ContractsD. Distribution Strategies For Decentralized TestingMarkets1. Marketing Approaches2. Product Complexity3. Customer Preference4. Established Suppliers5. Emerging Suppliers6. Major Types Of Distributors7. Market SegmentationPotential Market Entry Barriers And RisksA. Market MaturityB. Cost ContainmentC. CompetitionD. Technological Edge And LimitationsE. Patent ProtectionF. Regulatory ConstraintsG. Decentralized Testing Market Challenges
Competitive Profiles
- Abbott
- Affymetrix
- Agilent
- Applied Gene Technologies
- Arca
- Beckman Coulter/Danaher
- Becton Dickinson
- Biokit
- BioMerieux
- Bio-Rad
- Biotest
- Caliper
- Cepheid
- Decode
- Diadexus
- Eiken
- Enzo
- Exact Sciences
- Fujirebio
- Gen-Probe
- Hologic
- Illumina
- Innogenetics/Solvay
- Kreatech
- Li-Cor Biosciences
- Life Technologies
- Monogram Biosciences
- Myriad Genetics
- Nanogen/Elitech
- Novartis
- Orchid CellMark
- Ortho-Clinical Diagnostics
- Proteome Sciences
- Qiagen
- Roche
- Scienion
- Sequenom
- Shimadzu
- Siemens
- Sierra Molecular
- Takara Bio
- Tecan Group
AppendixesAppendix I: Major Universities and Research Centers
Developing NAT Technology
Appendix II: Glossary of Terms
Appendix III: Currency Exchange Rates
List of TablesMajor Companies Developing or Marketing AIDS NAT
And Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus
NAT And Other Direct Identification Tests
Major Companies Developing or Marketing Campylobacter
NAT And Other Direct Identification Tests
Major Companies Developing or Marketing Chlamydia
NAT And Other Direct Identification Tests
Major Companies Developing or Marketing CMV Molecular
Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular
Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Gonorrhea
NAT And Other Direct Identification Tests
Major Companies Developing or Marketing Hepatitis
NAT And Other Direct Identification Tests
Major Companies Developing or Marketing Herpes
NAT And Other Direct Identification Tests
Major Companies Developing or Marketing Legionella
NAT And Other Direct Identification Tests
Major Companies Developing or Marketing LymeDisease NAT And Other Direct Identification TestsMajor Companies Developing or Marketing MycoplasmaNAT And Other Direct Identification TestsMajor Companies Developing or Marketing PapillomaVirus NAT And Other Direct Identification TestsMajor Companies Developing or Marketing PneumoniaNAT And Other Direct Identification TestsMajor Companies Developing or Marketing SalmonellaNAT And Other Direct Identification TestsMajor Companies Developing or Marketing ShigellaNAT And Other Direct Identification TestsMajor Companies Developing or Marketing StreptococciNAT And Other Direct Identification TestsMajor Companies Developing or Marketing ToxoplasmosisNAT And Other Direct Identification TestsMajor Companies Developing or Marketing TuberculosisNAT And Other Direct Identification TestsOncogenes Potential Application in Cancer DiagnosisMajor Companies Developing or Marketing CancerNAT Tests
Major Companies Developing or Marketing NAT Assays
For Genetic Diseases
Summary Table U.S.A., NAT Test Volume
And Sales Forecast by Major Application
U.S.A., Laboratories Performing
DNA Sequencing by Market Segment
U.S.A., NAT Market, Potential
Laboratory Universe by Market Segment
U.S.A., NAT Test Volume Forecast By Major Application
U.S.A., Major Infectious Disease NAT Test Volume Forecast
U.S.A., Infectious Disease Screening
NAT Volume by Test Forecast
U.S.A., NAT Market Forecast By Major Application
U.S.A., Infectious Disease Screening Nat Reagent
Market Forecast by Test
U.S.A., NAT Market by Major Supplier
U.S.A., HIV/Hepatitis C NAT Market Reagent Sales
By Major Supplier
U.S.A., West Nile Virus NAT Market Reagent Sales
By Major Supplier
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Nicolas Bombourg
Reportlinker
Email: nbo@reportlinker.com
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Future US Nucleic Acid Testing Market Outlook
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