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Category Archives: Neurology
Cirrhosis: Phil’s story
From NHSChoices: Many people enjoy a drink in the pub after work without realising how social drinking can damage health. Phil didn't realise the harm his alcohol intake was doing until he was diagnosed with cirrhosis of the liver. He talks about his experience and the shock he felt at being diagnosed.
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Posted in Neurology
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What young doctors read
From the former BMJ Editor-in-Chief:
"I meet with young doctors all over the world, and I usually ask them what they read. I ask for a show of hands and find fairly consistently that half read the NEJM, the Lancet, a local journal, and a specialist journal, a third the BMJ, and most a local newspaper.
About half are reading a novel, and about a third have read a poem in the past week.
Almost all are on Facebook but very few on Twitter."
A lot of them also use Wikipedia as textbook replacement but they will not admit it unless asked directly.
Here, in the U.S., the majority of young doctors use UpToDate as a primary source, if the subscription is purchased by their hospital.
References:
Richard Smith: Review of “bring back browsing”. BMJ Blogs.
Image source: OpenClipArt.org, public domain.
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Posted in Neurology
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Cholesterol numbers – Mayo Clinic video
Mayo Clinic: You've heard the warnings before — high cholesterol increases your risk of heart disease. So how often should you get your cholesterol checked, what should your numbers be, and how do you get them there?
Heart numbers to know, from Cleveland Clinic
Knowing your risk for heart disease depends on knowing and understanding some important numbers:
- Blood pressure should be less than 120/80 mm Hg
- Fasting blood sugar should be less than 100 mg/dL
- Total cholesterol less than 200 mg/dL
- LDL (bad cholesterol) less than 100 mg/dL, HDL (good) greater than 40 mg/dL
- Waist circumference should be less than 40 inches for men and less then 35 inches for women
- Body Mass Index (BMI) should be between 18.5 and 25. Calculate your BMI here: http://bit.ly/glMJE5
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Posted in Neurology
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Medical educators around the world – Healthcare / HCSM / HIT Social Media List
Medical education around the world, a map by Anne Marie Cunningham: Add yourself so we can find people interested in medical education from all around the world.
Look at this short video for guidance on how to edit the map: http://www.screenr.com/vU2s
Here is a list of Healthcare / HCSM / HIT Social Media-related accounts around the world.
This is a list of the Top Twitter Doctors arranged by specialty in alphabetical order - feel free to add your own suggestions. The list is open to anybody to edit:
Related:
For doctors: How to be a Twitter superstar in two easy steps
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Posted in Neurology
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Celiprolol as treatment of choice to prevent complications in vascular Ehlers-Danlos syndrome
Vascular Ehlers-Danlos syndrome is a rare hereditary connective tissue disorder caused by mutations in the collagen type III gene ( COL3A1 ), which leads to a loss of tissue integrity in many organ systems.
Patients with vascular Ehlers-Danlos syndrome have weakened blood vessels and an increased risk of arterial dissection or rupture that can lead to early death.
The researchers assessed the ability of celiprolol, a ?1-adrenoceptor antagonist with a ?2-adrenoceptor agonist action, to prevent arterial dissections and ruptures in vascular Ehlers-Danlos syndrome.
Patients with clinical vascular Ehlers-Danlos syndrome were randomly assigned to 5 years of treatment with celiprolol or to no treatment.
33 patients were positive for mutation of collagen 3A1 (COL3A1). Celiprolol was uptitrated every 6 months by steps of 100 mg to a maximum of 400 mg twice daily. The primary endpoints were arterial events (rupture or dissection, fatal or not).
Mean duration of follow-up was 47 months, with the trial stopped early for treatment benefit.
The primary endpoints were reached by 20% in the celiprolol group and by 50% controls (hazard ratio [HR] 0·36).
Celiprolol might be the treatment of choice for physicians aiming to prevent major complications in patients with vascular Ehlers-Danlos syndrome.
References:
Effect of celiprolol on prevention of cardiovascular events in vascular Ehlers-Danlos syndrome: a prospective randomised, open, blinded-endpoints trial. The Lancet, Volume 376, Issue 9751, Pages 1476 - 1484, 30 October 2010.
Celiprolol therapy for vascular Ehlers-Danlos syndrome. The Lancet, Volume 376, Issue 9751, Pages 1443 - 1444, 30 October 2010.
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Twitter epidemics – BMJ video
BMJ medical innovations: During the swine flu pandemic, Google showed that it was able to track the spread using the searches that its users were making. In this video Dr Patty Kostkova shows her work using twitter - and how the data from that could be used to track future epidemics.
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