Category Archives: Medical School

HERSHAW DAVIS JR., LEFT,said he is trying to eat better and exercise more to control his weight, but finds his 12-hour, overnight shift as an ER nurse at Johns Hopkins Hospital makes it difficult. (GABRIELLA DEMCZUK | THE BALTIMORE SUN)

Taylor DesRosiers was a competitive swimmer throughout her life, always fit. But in her first year of medical school, she realized that had changed - she was at an unhealthy weight.

The rigors of her education had piled on top of two rough years in which she went through a broken-off engagement and supporting her mother through a health scare. During a course on obesity, she realized, according to body mass index charts, she was technically obese herself.

"It just kind of hit me: I need to make a large change," DesRosiers said.

She had some support in doing that: Two fellow Johns Hopkins University students recently launched the Patient Promise, a program that aims to ensure health professionals do as they tell patients when it comes to healthy lifestyles. It is one of many similar programs to arise in the industry as health professionals seek to tackle rising obesity rates nationwide by starting with themselves. (Lakeland Regional Medical Center, for example, offers Living Well: Lakeland Regional's Culture of Health. It includes classes on nutrition, diabetes, smoking cessation and more, as well as an exercises series and health screenings.)

Research has shown that healthy lifestyle choices on the part of physicians can translate into better care for obese patients. That care is important as the health industry seeks to tackle the rising costs of care, particularly for many chronic conditions that can stem from obesity.

About 36 percent of adults in the U.S. are obese, according to the Centers for Disease Control. For a 5-foot-4-inch adult, a weight above 174 pounds is considered obese, while a 5-foot-9-inch person weighing 203 or more would qualify, for example. Obesity-related conditions like heart disease, stroke, diabetes and some types of cancer are among the leading causes of death.

Hopkins students Shiv Gaglani and David Gatz started talking about the idea behind the Patient Promise early this year, realizing that their career choices were taking a toll on their health.

"Our own healthy-lifestyle behaviors were going out the window," Gaglani said, given time spent sedentary in classes or studying and busy schedules leaving little room for exercise or healthy cooking. "It's sort of a sacrificial career. By sacrificing our own health, we would become potentially less effective as clinicians because we wouldn't be credible."

The pair got about a dozen students together, including DesRosiers, to draft the Patient Promise, and they launched it in June. Within a few weeks, 300 medical professionals and students across the country had signed it, and the organizers plan to raise that to a few thousand eventually.

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Medical Professionals Not Always Leading Healthy Lifestyles

In 2011, final-year University of Adelaide medical students Rachel Jones and Ben Rogers were looking forward to gaining rural practice experience. Now their uni is doubling the number of interviews with rural candidates. Picture: Calum Robertson Source: The Advertiser

THE University of Adelaide's medical school aims to double the number of rural students it interviews for places with changes to its entry process.

From this year the university will consider rural applicants' Undergraduate Medicine and Health Sciences Admission Test scores separately from metropolitan applicants in a bid to ensure more get through to the interview stage.

The university hopes to interview about 120 rural students, up from the 61 it saw for this year's cohort.

Faculty of Health Sciences executive dean Professor Justin Beilby acknowledged rural students were under-represented but hoped the changes would see growth.

University of Adelaide second-year medicine student Matt Watson, from Tooligie on the Eyre Peninsula, said: "Where I'm from, the only person I could talk to who'd got into medicine was the GP."

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Uni targets rural medical students

August 9, 2012 Grant to benefit Columbia-Bassett Medical School student

Anonymous The Cooperstown Crier Thu Aug 09, 2012, 10:20 PM EDT

The Central New York KeyBank Foundation Committee has awarded Friends of Bassett Healthcare Network a four-year grant of $120,000 to provide scholarship support for one student over the course of their four year Columbia-Bassett Medical School experience beginning this fall, according to a media release from Bassett.

Innovative ways of attracting highly skilled physicians to practice in rural areas are crucial given the changing health care environment, Stephen D. Fournier, president of KeyBanks Central New York District said in the release. The Columbia-Bassett program goes well beyond that by also preparing medical school students to lead the health systems of the future, and thats why KeyBank felt it was important to demonstrate the Foundations support of the program in such a meaningful way.

Columbia-Bassett Assistant Dean for Education Dr. Henry Weil said in the release that the KeyBank grant will be life changing for the student who receives it.

Young physicians coming out of medical school face educational debts that can exceed $200,000, which forces them to make career decisions based upon maximizing their earning potential, Weil said. Our goal has been to make rural practice a more attractive and viable option by limiting future debt through substantial financial assistance, like the scholarship KeyBank will provide to one deserving medical school student.

The Columbia-Bassett Medical School Program is a collaborative endeavor of Bassett Medical Center in Cooperstown and the College of Physicians and Surgeons at Columbia University in New York City. The program annually recruits 10 exceptional students with an interest in providing care in underserved rural communities and learning how to manage health care systems that promote both quality and cost-effective delivery of care. Bassett Medical Center underwrites the cost of education for the students, providing $30,000 in scholarships per year per student. The students spend their first 18 months learning the basic science curriculum with the rest of their class in New York City, but their clinical training for the following two-and-one-half years is based at Bassett Medical Center.

According to the release, this unique program attracts more than 750 applicants each year for the 10 slots. Applicants are from across the country and are among the most qualified of those applying to medical school.

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Grant to benefit Columbia-Bassett Medical School student

Dr. Craig Brater will retire in June next year as dean of the Indiana University School of Medicine, he announced Wednesday, and the school has formed a committee to find his replacement.

Brater, 66, has worked at the Indianapolis-based school for 26 years, including the past 12 as dean. The school is the second largest medical school in the nation and the only one in Indiana.

Brater oversees a massive operation that includes a main campus in Indianapolis and eight satellite campuses throughout the state.

The medical school had a budget of nearly $426 million in the last school year, up by 30 percent over the past five years. It employs 1,900 professors who oversee a total student body of 1,880 and also serve as doctors at five hospitals in Indianapolis, including Wishard Memorial Hospital, the Roudebush Veterans Affairs Medical Center, as well as IU Healths University Hospital and Riley Hospital for Children.

Craig Brater has done a superb job leading the IU School of Medicine for the past 12 years and working in close partnership with IU Health and our other clinical partners," said IU President Michael McRobbie in a prepared statement announcing the launch of a national search for Braters replacement. "He has effectively and skillfully positioned the school as a research and clinical leader.

IU has formed a 20-member search committee, which will be led by John Williams, dean of the IU School of Dentistry. Other members of the committee include Dan Evans, CEO of the IU Health hospital system; Dr. Lisa Harris, CEO of Wishard Health Services; and Marion Broome, dean of the IU School of Nursing.

That committee will identify and screen prospective candidates, then recommend a group of finalists to McRobbie and to Charles Bantz, the chancellor of the IUPUI campus, where the medical school is based.

The search committee will be helped by an outside advisory committee, which will be chaired by Chuck Schalliol, a life sciences attorney at Faegre Baker & Daniels LLP, who is a former manager at Eli Lilly and Co. and the former CEO of BioCrossroads, an Indianapolis-based life sciences development group.

Brater is a native of Oak Ridge, Tenn. He attended undergraduate and medical school at Duke University. Before IU, he was part of the faculty at the University of California at San Francisco and worked for the University of Texas Southwestern Medical Center.

Brater and his wife Stephanie have one grown daughter who lives in Florida.

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Brater to retire as dean of IU medical school

Public release date: 7-Aug-2012 [ | E-mail | Share ]

Contact: Mark L. Shelton mark.shelton@umassmed.edu 508-856-2000 University of Massachusetts Medical School

BOSTON, Mass. A pivotal clinical trial for an anti-rabies human monoclonal antibody (RMAb) being developed through a collaborative partnership between MassBiologics of the University of Massachusetts Medical School and the Serum Institute of India, Ltd., is starting to enroll patients. The study, sponsored by the Serum Institute, will evaluate the efficacy of post-exposure prophylaxis following rabies exposure with RMAb and vaccine compared to standard treatment of human rabies immune globulin (hRIG) and vaccine. Post-exposure prophylaxis for rabies that includes a monoclonal antibody should provide a more affordable, safer alternative to prevent the disease, which is a world-wide public health problem impacting 10 million people a year and resulting in some 55,000 deaths.

"We are extremely pleased that this potentially life-saving product has moved forward to the pivotal clinical trial phase," said Deborah Molrine, MD, deputy director of Clinical and Regulatory Affairs at MassBiologics and an associate professor of pediatrics at UMass Medical School. "Rabies is a major public health problem in Asia and Africa, and we are hopeful that the findings of this study may result in a treatment option readily available in those areas where it is needed most."

The randomized, comparator-controlled study being conducted in India will enroll 200 patients who have had a high-risk (category III as defined by the World Health Organization) exposure to a suspected rabid animal. Study participants will receive proper wound care followed by injections of either the investigational RMAb or standard hRIG treatment in combination with a five-dose rabies vaccine series.

The primary endpoint of the study is to demonstrate that the level of neutralizing antibody to rabies virus in the blood of participants who received RMAb and vaccine is at least as much as the level of anti-rabies neutralizing antibody in the blood of those who received hRIG and vaccine.

While deaths from rabies in the United States are rare, rabies remains a significant problem with approximately 95 percent of human deaths from rabies occurring in Asia and Africa. Death from rabies is preventable with timely post-exposure prophylaxis consisting of wound hygiene, administration of rabies immune globulin, and active immunization with rabies vaccine. In persons wounded by a suspected rabid animal, the vaccine works to stimulate the immune system to fight the rabies virus, while the rabies immune globulin provides immediate protection with neutralizing antibodies before the immune system begins making its own antibodies.

Human rabies immune globulin, derived from human blood, is an expensive product and carries a potential risk of contamination with blood-borne pathogens. Equine immune globulin (eRIG), derived from horse serum, is used in many parts of the world, but its use is associated with significant adverse effects such as anaphylaxis or serum sickness. Both products are often in short supply and costly for inhabitants of areas of the world where rabies is endemic. In India alone, it is estimated only 2 percent of patients whose wounds require the rabies immune globulin receive appropriate post-exposure treatment.

To address the supply and adverse effects issues, MassBiologics and the U.S. Centers for Disease Control and Prevention developed an anti- rabies monoclonal antibody with the goal that it might be used in place of hRIG or eRIG. MassBiologics then partnered with the Serum Institute to develop and manufacture the monoclonal antibody in India. "A monoclonal antibody for rabies has the advantage of being able to be produced in large quantities, at much lower costs than blood products," said Prasad Kulkarni, MD, medical director at the Serum Institute of India, Ltd. "And since they are not derived from blood serum, they have none of the safety issues associated with human blood products. If the primary endpoint from this pivotal trial is met, a new therapy could become available to thousands of patients each year to prevent the too-often fatal outcome of this infection."

In a phase 1 trial at the King Edward Memorial Hospital (KEM) in Mumbai, India, 74 healthy volunteers were randomized into several groups that either received RMAb or of hRIG combined with vaccine. Results showed that the RMAb was well tolerated by all subjects, with no serious side-effects. A dose of RMAb was selected from this study that produced comparable levels of rabies virus neutralizing antibodies in the blood from volunteers who received RMAb and vaccine compared to those who received the standard regimen of hRIG and vaccine.

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Clinical trial for rabies monoclonal antibody

A chemical spill prompted firefighters to evacuated a Harvard Medical School building for several hours Tuesday afternoon after a doctor working in a lab spilled several large bottles of acids, according to firefighters.

The doctor went to get a bottle off a shelf in a 10th floor lab on Avenue Louis Pasteur at about 3 p.m. and inadvertantly knocked three bottles containing acids, which rolled off the shelf and smashed, said Boston Fire Department spokesman Steve MacDonald.

The doctor, who was dressed in protective lab clothing, followed protocol and immediately jumped under a lab shower to decontaminate herself, said MacDonald, who told the Herald no one was injured in the spill.

MacDonald said Harvard hired a cleanup company to clean up the spilled bottles, which were about two liters each and contained acetic and hydrochloric acids.

Acetic acid is flammable and both acids are irritants. They can cause burns if you come in contact with them and they can cause some distress if you inhale the chemicals, said MacDonald.

Boston firefighters, who sealed off the street during the incident, also conducted air quality readings to ensure the 10-story medical school building was safe, according to MacDonald.

Harvard Medical School issued a statement saying the chemical spill on the buildings top floor happened in the Department of Microbiology and Immunobiology and confirmed the top three floors of the building would remain evacuated until further notice.

A Harvard Medical spokeswoman declined to say whether the incident would prompt a review of chemical storage practices in the labs.

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Acid spill at Harvard Med School prompts evacuation