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Is this Scotland’s oldest cat? | HeraldScotland – HeraldScotland

HE may not be quite as old as his cartoon namesake but at the grand old age of 26, Snoopy could well be Scotland's oldest cat.

The hardy rescue moggy, who has clawed his way up the equivalent of 120 human years, was discovered abandoned and 'near feral' in the gutter and was the runt of the litter, according to his owner.

However, the six-week-old kitten thrived under the care of his new family and even overcame cat flu - which can often be fatal in felines.

The average lifespan for a domestic cat in the UK is 14 with animals described as geriatric if they survive beyond 15.

Snoopy may be frail but apart from losing his hearing he has no other health problems and is now enjoying the high life with the odd potter around the garden and regular helpings of his favourite meal of mince and tatties.

READ MORE: Donations pour in after death of wildcat kitten Huntleigh

His owner Lorraine Leskovec, 57, says she's amazed by his longevity - he's survived three other, younger cats.

"I've always felt that when I've lost other cats that they have left a bit of themselves in Snoopy," she said.

"He's a good old boy. As far as I remember, I had been looking for a kitten for a wee while and phoning the cat and dog home because at that time they were hard to get.

"They phoned me one morning to say they had a litter of kittens in. So we went down and there was a wee one that kept hiding in the corner and he was the runt of the litter and I thought that's the one I'm having.

READ MORE: Huntleighthe rescued wildcat kitten passes away

"He used go outside a lot but now it's just now and again. In the Summer he loves to finda sunny spot but not in this cold weather, he's too frail now.

"When he was younger he was quite robust, he was quitethe cat of the town," added Snoopy's owner, who lives in Carnwath, near Lanark andhas another Ragdoll cat called Rocky, who is blind.

"His appetite has gone through the roof but I think that is part of being an older cat. At the moment he will eat everything from mince and tatties to cheese. He gets what he wants now."

Cats may not really have nine lives, but factors such as diet, healthcare and environment can have an impact on how long they live.

Older catsgenerally succumb to illnesses such as kidney disease, arthritis, congestive heart failure, liver disorders, and renal disease.

READ MORE: Cat missing for 12 years re-homed after living as a stray on the shores of Loch Lomond

The oldest cat ever, according to the record books was called Creme Puff. It was born on 3 August, 1967, and lived for 38 years and three days.

"I would never have thought he would have lived to this age, " said Ms Leskovec, who works for Tesco.

"He's an amazing cat. Every day I say to my partner, 'IsSnoopy still breathing?' I'm hoping he will just slip away when the time comes."

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Longevity and Anti-senescence Therapy Market 2020 Study Report by Industry Types, Growth, Share, Size, Key Manufacturers, Revenue, Trends, COVID-19…

The Longevity and Anti-senescence Therapy market is expected to grow from USD X.X million in 2020 to USD X.X million by 2026, at a CAGR of X.X% during the forecast period. The global Longevity and Anti-senescence Therapy market report is a comprehensive research that focuses on the overall consumption structure, development trends, sales models and sales of top countries in the global Longevity and Anti-senescence Therapy market. The report focuses on well-known providers in the global Longevity and Anti-senescence Therapy industry, market segments, competition, and the macro environment.

Under COVID-19 Outbreak, how the Longevity and Anti-senescence Therapy Industry will develop is also analyzed in detail in Chapter 1.7 of the report., In Chapter 2.4, we analyzed industry trends in the context of COVID-19., In Chapter 3.5, we analyzed the impact of COVID-19 on the product industry chain based on the upstream and downstream markets., In Chapters 6 to 10 of the report, we analyze the impact of COVID-19 on various regions and major countries., In chapter 13.5, the impact of COVID-19 on the future development of the industry is pointed out.

A holistic study of the market is made by considering a variety of factors, from demographics conditions and business cycles in a particular country to market-specific microeconomic impacts. The study found the shift in market paradigms in terms of regional competitive advantage and the competitive landscape of major players.

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Key players in the global Longevity and Anti-senescence Therapy market covered in Chapter 4:, Acorda Therapeutics, Unity Biotechnology, Antoxerene, Celgene, Cohbar, Senex Biotechnology, Human Longevity Inc., T.A. Sciences, Agex Therapeutics, Recursion Pharmaceuticals, Calico Life Sciences, Spotlight Bioscience, Powervision Inc., Sierra Sciences Llc, Restorbio, Insilico Medicine, Oisin Biotechnology, Senolytic Therapeutics, Proteostasis Therapeutics Inc., Prana Biotechnology Ltd., Cleara Biotech

In Chapter 11 and 13.3, on the basis of types, the Longevity and Anti-senescence Therapy market from 2015 to 2026 is primarily split into:, Senolytic Drug Therapy, Gene Therapy, Immunotherapy, Others

In Chapter 12 and 13.4, on the basis of applications, the Longevity and Anti-senescence Therapy market from 2015 to 2026 covers:, Longevity, Senescence Inhibition, Cardiovascular Diseases, Neural Degenerative Diseases, Ophthalmology Disorders, Cancer

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Geographically, the detailed analysis of consumption, revenue, market share and growth rate, historic and forecast (2015-2026) of the following regions are covered in Chapter 5, 6, 7, 8, 9, 10, 13:, North America (Covered in Chapter 6 and 13), United States, Canada, Mexico, Europe (Covered in Chapter 7 and 13), Germany, UK, France, Italy, Spain, Russia, Others, Asia-Pacific (Covered in Chapter 8 and 13), China, Japan, South Korea, Australia, India, Southeast Asia, Others, Middle East and Africa (Covered in Chapter 9 and 13), Saudi Arabia, UAE, Egypt, Nigeria, South Africa, Others, South America (Covered in Chapter 10 and 13), Brazil, Argentina, Columbia, Chile, Others, Regional scope can be customized

Years considered for this report:, Historical Years: 2015-2019, Base Year: 2019, Estimated Year: 2020, Forecast Period: 2020-2026

Some Point of Table of Content:

Chapter One: Report Overview

Chapter Two: Global Market Growth Trends

Chapter Three: Value Chain of Longevity and Anti-senescence Therapy Market

Chapter Four: Players Profiles

Chapter Five: Global Longevity and Anti-senescence Therapy Market Analysis by Regions

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Chapter Six: North America Longevity and Anti-senescence Therapy Market Analysis by Countries

Chapter Seven: Europe Longevity and Anti-senescence Therapy Market Analysis by Countries

Chapter Eight: Asia-Pacific Longevity and Anti-senescence Therapy Market Analysis by Countries

Chapter Nine: Middle East and Africa Longevity and Anti-senescence Therapy Market Analysis by Countries

Chapter Ten: South America Longevity and Anti-senescence Therapy Market Analysis by Countries

Chapter Eleven: Global Longevity and Anti-senescence Therapy Market Segment by Types

Chapter Twelve: Global Longevity and Anti-senescence Therapy Market Segment by Applications 12.1 Global Longevity and Anti-senescence Therapy Sales, Revenue and Market Share by Applications (2015-2020) 12.1.1 Global Longevity and Anti-senescence Therapy Sales and Market Share by Applications (2015-2020) 12.1.2 Global Longevity and Anti-senescence Therapy Revenue and Market Share by Applications (2015-2020) 12.2 Longevity Sales, Revenue and Growth Rate (2015-2020) 12.3 Senescence Inhibition Sales, Revenue and Growth Rate (2015-2020) 12.4 Cardiovascular Diseases Sales, Revenue and Growth Rate (2015-2020) 12.5 Neural Degenerative Diseases Sales, Revenue and Growth Rate (2015-2020) 12.6 Ophthalmology Disorders Sales, Revenue and Growth Rate (2015-2020) 12.7 Cancer Sales, Revenue and Growth Rate (2015-2020)

Chapter Thirteen: Longevity and Anti-senescence Therapy Market Forecast by Regions (2020-2026) continue

List of tablesList of Tables and Figures Table Global Longevity and Anti-senescence Therapy Market Size Growth Rate by Type (2020-2026) Figure Global Longevity and Anti-senescence Therapy Market Share by Type in 2019 & 2026 Figure Senolytic Drug Therapy Features Figure Gene Therapy Features Figure Immunotherapy Features Figure Others Features Table Global Longevity and Anti-senescence Therapy Market Size Growth by Application (2020-2026) Figure Global Longevity and Anti-senescence Therapy Market Share by Application in 2019 & 2026 Figure Longevity Description Figure Senescence Inhibition Description Figure Cardiovascular Diseases Description Figure Neural Degenerative Diseases Description Figure Ophthalmology Disorders Description Figure Cancer Description Figure Global COVID-19 Status Overview Table Influence of COVID-19 Outbreak on Longevity and Anti-senescence Therapy Industry Development Table SWOT Analysis Figure Porters Five Forces Analysis Figure Global Longevity and Anti-senescence Therapy Market Size and Growth Rate 2015-2026 Table Industry News Table Industry Policies Figure Value Chain Status of Longevity and Anti-senescence Therapy Figure Production Process of Longevity and Anti-senescence Therapy Figure Manufacturing Cost Structure of Longevity and Anti-senescence Therapy Figure Major Company Analysis (by Business Distribution Base, by Product Type) Table Downstream Major Customer Analysis (by Region) Table Acorda Therapeutics Profile Table Acorda Therapeutics Production, Value, Price, Gross Margin 2015-2020 Table Unity Biotechnology Profile Table Unity Biotechnology Production, Value, Price, Gross Margin 2015-2020 Table Antoxerene Profile Table Antoxerene Production, Value, Price, Gross Margin 2015-2020 Table Celgene Profile Table Celgene Production, Value, Price, Gross Margin 2015-2020 Table Cohbar Profile Table Cohbar Production, Value, Price, Gross Margin 2015-2020 Table Senex Biotechnology Profile Table Senex Biotechnology Production, Value, Price, Gross Margin 2015-2020 Table Human Longevity Inc. Profile Table Human Longevity Inc. Production, Value, Price, Gross Margin 2015-2020 Table T.A. Sciences Profile Table T.A. Sciences Production, Value, Price, Gross Margin 2015-2020 Table Agex Therapeutics Profile Table Agex Therapeutics Production, Value, Price, Gross Margin 2015-2020 Table Recursion Pharmaceuticals Profile Table Recursion Pharmaceuticals Production, Value, Price, Gross Margin 2015-2020 Table Calico Life Sciences Profile Table Calico Life Sciences Production, Value, Price, Gross Margin 2015-2020 Table Spotlight Bioscience Profile Table Spotlight Bioscience Production, Value, Price, Gross Margin 2015-2020 Table Powervision Inc. Profile Table Powervision Inc. Production, Value, Price, Gross Margin 2015-2020 Table Sierra Sciences Llc Profile Table Sierra Sciences Llc Production, Value, Price, Gross Margin 2015-2020 Table Restorbio Profile Table Restorbio Production, Value, Price, Gross Margin 2015-2020 Table Insilico Medicine Profile Table Insilico Medicine Production, Value, Price, Gross Margin 2015-2020 Table Oisin Biotechnology Profile Table Oisin Biotechnology Production, Value, Price, Gross Margin 2015-2020 Table Senolytic Therapeutics Profile Table Senolytic Therapeutics Production, Value, Price, Gross Margin 2015-2020 Table Proteostasis Therapeutics Inc. Profile Table Proteostasis Therapeutics Inc. Production, Value, Price, Gross Margin 2015-2020 Table Prana Biotechnology Ltd. Profile Table Prana Biotechnology Ltd. Production, Value, Price, Gross Margin 2015-2020 Table Cleara Biotech Profile Table Cleara Biotech Production, Value, Price, Gross Margin 2015-2020 Figure Global Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Global Longevity and Anti-senescence Therapy Revenue ($) and Growth (2015-2020) Table Global Longevity and Anti-senescence Therapy Sales by Regions (2015-2020) Table Global Longevity and Anti-senescence Therapy Sales Market Share by Regions (2015-2020) Table Global Longevity and Anti-senescence Therapy Revenue ($) by Regions (2015-2020) Table Global Longevity and Anti-senescence Therapy Revenue Market Share by Regions (2015-2020) Table Global Longevity and Anti-senescence Therapy Revenue Market Share by Regions in 2015 Table Global Longevity and Anti-senescence Therapy Revenue Market Share by Regions in 2019 Figure North America Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Europe Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Asia-Pacific Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Middle East and Africa Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure South America Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure North America Longevity and Anti-senescence Therapy Revenue ($) and Growth (2015-2020) Table North America Longevity and Anti-senescence Therapy Sales by Countries (2015-2020) Table North America Longevity and Anti-senescence Therapy Sales Market Share by Countries (2015-2020) Figure North America Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2015 Figure North America Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2019 Table North America Longevity and Anti-senescence Therapy Revenue ($) by Countries (2015-2020) Table North America Longevity and Anti-senescence Therapy Revenue Market Share by Countries (2015-2020) Figure North America Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2015 Figure North America Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2019 Figure United States Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Canada Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Mexico Longevity and Anti-senescence Therapy Sales and Growth (2015-2020) Figure Europe Longevity and Anti-senescence Therapy Revenue ($) Growth (2015-2020) Table Europe Longevity and Anti-senescence Therapy Sales by Countries (2015-2020) Table Europe Longevity and Anti-senescence Therapy Sales Market Share by Countries (2015-2020) Figure Europe Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2015 Figure Europe Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2019 Table Europe Longevity and Anti-senescence Therapy Revenue ($) by Countries (2015-2020) Table Europe Longevity and Anti-senescence Therapy Revenue Market Share by Countries (2015-2020) Figure Europe Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2015 Figure Europe Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2019 Figure Germany Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure UK Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure France Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Italy Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Spain Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Russia Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Asia-Pacific Longevity and Anti-senescence Therapy Revenue ($) and Growth (2015-2020) Table Asia-Pacific Longevity and Anti-senescence Therapy Sales by Countries (2015-2020) Table Asia-Pacific Longevity and Anti-senescence Therapy Sales Market Share by Countries (2015-2020) Figure Asia-Pacific Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2015 Figure Asia-Pacific Longevity and Anti-senescence Therapy Sales Market Share by Countries in 2019 Table Asia-Pacific Longevity and Anti-senescence Therapy Revenue ($) by Countries (2015-2020) Table Asia-Pacific Longevity and Anti-senescence Therapy Revenue Market Share by Countries (2015-2020) Figure Asia-Pacific Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2015 Figure Asia-Pacific Longevity and Anti-senescence Therapy Revenue Market Share by Countries in 2019 Figure China Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Japan Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure South Korea Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Australia Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure India Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Southeast Asia Longevity and Anti-senescence Therapy Sales and Growth Rate (2015-2020) Figure Middle East and Africa Longevity and Anti-senescence Therapy Revenue ($) and Growth (2015-2020) continue

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Families hope bill will help them help loved ones living in nursing homes during the pandemic – The Boston Globe

But nursing homes and assisted living facilities closed to visitors last March, as outbreaks of COVID-19 sickened and killed hundreds of people in their facilities. It was months before they allowed even limited, distanced visits nothing like the one-on-one caregiving that Ferraro and others had done for their family members before the pandemic.

Our loved ones they cant tell us. My husband cant communicate with me anymore, Ferraro said. I call every day, if I can get through, and see if the CNA can bring the phone in and (he can) hear my voice. Hell babble but sometimes he wont say anything. Ill try to imagine how he is.

When Governor Gina M. Raimondo announced last month that the Health Department had agreed to allow nursing homes and assisted living facilities to permit certain relatives and close friends of patients to be essential caregivers, Ferraro and other families were hopeful. Theyd been pushing the Raimondo Administration and local legislators to enact something like the Essential Caregiver Program for Nursing Homes and Assisted Living Facilities, similar to programs in other states.

But there was a caveat: The governor was leaving it up to nursing homes to decide whether they wanted to participate. We are not forcing this on any nursing home, Raimondo said on Dec. 18. Nursing homes have their hands full and we want to be supportive. However, its a path to allow family members to visit and take care of their loved ones.

To the frustration of families, very few have made it an option.

Charles Galligan, whose mother, Audrey, is at St. Elizabeths Manor in Bristol, calls the ongoing isolation of residents there inhumane. Theyre preserving their longevity and stripping their lives of meaning, he said.

Now, the families are hoping for some mercy from the General Assembly. The Senate Committee on Health and Human Services is holding a hearing on a bill at 4 p.m. Thursday that would give the governors recommendation some teeth. The legislation amends the Rights of Nursing Home Patients state law by adding a provision for essential caregivers during a declared emergency. The meeting will be televised by Capitol Television and livestreamed at http://www.rilegislature.gov/CapTV/Pages/default.asp.

The bill, sponsored by Cranston Senator Frank S. Lombardi, would require the Health Department to promulgate rules and regulations to designate essential caregivers for residents of nursing homes and long-term care facilities during an emergency declaration.

Trish and Maria Tavarozzi, whose mother, Elena, is also at St. Elizabeths Home, said the families are invested in the care of their loved ones and eager to be trained, tested, and wear personal protective equipment to keep the residents safe. They believe that having family members as essential caregivers can relieve the burdens on overtaxed health care workers and relieve the isolation of the residents.

They are in prison for a crime they didnt commit, Maria Tavarozzi said.

However, Scott Fraser, president and CEO of the Rhode Island Health Care Association, which represents nursing homes in Rhode Island, said the essential caregiver program is an extra burden.

In theory, its a nice concept, but the timing with COVID outbreaks, preparing for visitations, and vaccines, its a lot to ask of our members, Fraser said.

First and foremost, the battle is to keep COVID out and treat those who have it, he added. And to be asked to put together an essential caregiver program at the same time that were getting permissions for the vaccine, thats a lot coming at our members at once.

As of Jan. 15, almost all of the nursing homes have been visited by vaccination teams at least once, according to the Health Department. The roll-out of the vaccination program at nursing homes has been dependent on the supply of COVID-19 vaccine received by the state.

Kathleen Heren, Rhode Islands longterm care ombudsman, said shes aware of one nursing home that has refused to take part in the essential caregiver program. Others may be hesitating out of safety concerns, she said.

I can understand. This is probably not the best time to roll it out, Heren said.

But the whole point of the essential caregivers legislation is to help nursing homes and patients during the pandemic, the families say. They are the only ones who can advocate for the care of their loved ones, and they feel like theyve been cast aside.

Its horrible. Its indescribable, said Ferraro. When your loved one gets a diagnosis of Alzheimers, you prepare for a certain journey and you prepare to see them through. And to have it ripped out from under us, I cant put it into words.

Amanda Milkovits can be reached at amanda.milkovits@globe.com. Follow her on Twitter @AmandaMilkovits.

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New Year, New Noise: 2021 predictions | UNLIMITED | Open Mic – The Drum

The 2021 predictions to back are the ones grounded in genuine

human understanding

The beginning of every year always sees a wave of inspirational trends look ahead pieces. The full-on bombardment of thinking often makes it hard to tell which are grounded in fact, which are just blue-sky thinking and who really is on the money.

There is an even greater onslaught of this will happen thinking out there than normal, partly since so many of last years forecasts went out of the window at the start of March. Also, arguably, no year in history has been more eagerly anticipated than 2021, with consumers battling conflicting emotions:

The hope that it will be better than 2020 and a collective determination to make it so

A nagging concern that it will be just as bad as last year

This makes it only natural for marketers to look even more closely than usual at the body of published trends work: which trends to believe and, more crucially, which to pin their companys 2021 on? Of course, it doesnt help when the various POVs are awash with contradictions and vested interests, or when there are so many.

Thats why weve done the hard work for marketers, ploughing our way through 30+ of the 2021 lookaheads in the public domain. Weve added our own expertise, backed by leading edge research, and run the ideas past our gold-standard teams specialising in comms, marketing and digital.

Based on all of that, here is our pick of 10 trends. Five in the consumer space and five in the marketing space to focus on.

5 Consumer trends to focus on

1. A changing relationship with physical spaces, town centres and a heightened focus on the local.

25% of UK urbanites want to move out of the metropolitan areas where they currently live

2. Sustainability: a green (re)awakening the end of more, moving away from big lifestyles, contentment with less, reducing waste.

72% of global consumers said companies behaving sustainably was more important to them because of COVID-19

3. A new fluidity. Weve lost many of the rituals that used to signpost our lives resulting in a sense of collective displacement. We may have replaced them with digital equivalents but over the coming year(s) well see a more proactive emergence of new models and rules.

Microsoft Japans experiment with a four-day workweek earlier this year resulted in a 40% in worker productivity.

4. In 2021, well see the emergence of a newly resilient consumer, taking control of their lives, balancing forward planning with an ability to roll with the punches, and innovating their own solutions.

Studies show that consumers are significantly more likely to try new brands when they go through a major life event.

5. Kindness culture and a return to we as the new-found appreciation of others will manifest itself in a greater focus on community, helpfulness, kindness, support, and empathy.

39% of those living with friends/roommates are concerned about their mental wellbeing.

5 Marketing trends to focus on

1. Organising for agility and flex. With the economy more unpredictable than ever, and with companies having all of last years pivoting stories fresh in their minds, organisations will be trying to be disruption-ready, setting themselves up in such a way that they can rapidly alter course to take account of any new wind direction.

82% said when brands pivoted to offer new, more relevant products or services it increased their desire to do more business with them.

2. Taking customer experience to the max. The rise of DTC will continue. Brands will shift the bar ever higher on service. The emphasis in delivery will shift from last mile to last few feet as organisations realise that product handovers represent something too important to trust to time pressured and disinterested couriers.

62% of marketers agreed that they actively consider the impact of packaging and delivery on customer experience.

3. 2021 will see brand purpose get real as consumers demand brands walk the walk as well as talking the talk with firm brand promises or pledges and acts not mere words.

60% of millennials & Gen Z say they plan on buying more from large businesses that have taken care of their workforces and positively affected society during the pandemic

4. The holy grail of distinctiveness: COVID was such a powerful disruptor that it encouraged convergence of product offerings and marketing message channel choice content, tone, and execution. 2021 will see brands making concerted efforts to refind themselves and re-express their uniqueness though such high-risk strategies are bound to create both winners and losers.

64% of marketers agree that advertising suffered from a lack of distinctiveness during quarantine, and there is a danger that this will persist

5. E-commerce innovation will surge. 2021 will see innovation in what online retail looks and feels like well see shoppable social surge ahead, purchasing via livestreaming take off, and efforts to make the online shopping process look and feel more like being in store, start to bear fruit.

In China, a Tommy Hilfiger livestream event attracted 14 million viewers and sold out of 1,300 hoodies in two minutes

Focus on Human Understanding signals, not noise

With so much noise out there, the brands that thrive in 2021 will be the ones that can correctly pick out the ones that fit a consumer truth and offer real longevity.

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What are longevity supplements, and are they safe? – MarketWatch

Aches and pains. A growing waistline. Diminishing eyesight, hearing loss, memory lapses. These are the woes of growing older for some people, once considered inevitable. But recent, exciting discoveries in the fast-growing field of longevity science have some doctors and researchers pronouncing that these symptoms of aging may one day be treatable with pharmaceuticals, gene therapies or other yet-to-be-discovered medical technologies.

Many people havent been content to wait, though. Dozens of commercial producers are selling hundreds of so-called longevity supplements right now, and sales data suggest anawful lot of peopleare trying them. But do they work? Are they even safe?

To find out, we scoured the latest research and interviewed two top scientists in the field. What we learned suggests that you may want to hold off on ordering a supply, or at least do your research very carefully.

There is a solid handful of compounds that look very promising in the scientific quest to slow the aging process. One of the most exciting is nicotinamide adenine dinucleotide, or NAD, which has been shown to extend both the lifespans and youthful function of yeast and animals in clinical trials. Human trials are ongoing, with only a handful published to date.

NAD (also often written as NAD+) is a substance found in every cell in your body, which controls all kinds of metabolic processes, including the regulation of sirtuins, the so-called longevity genes. As you age, your NAD+ levels decline, and scientists think it is perhapsthisdecline that leads toall sortsof other age-related declines.

Also read: Should you invest in the new longevity funds?

The working theory, then, is that if we can boost our NAD+ levels as we age, we can slow our decline tremendously. Lab studies on yeast and rodentslend strong supportto that theory. The most recent studies have primarily involved the administration of either nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN), which is then converted into NAD in the body.

To learn more about NAD, Next Avenue talked to Dr. Shin-Ichiro Imai, professor of developmental biology at the Washington University School of Medicine in St. Louis. Along with Leonard Guarente, Imai discovered the link between NAD and sirtuin control in 1999. Hes been studying the molecule ever since.

There have been 10 human clinical trials using NR, most at very high dose, with no safety issues, Imai said. Most of those trials, however, lasted for a duration of weeks or months at most.

Is it safe to take NAD-boosting supplements continuously, for years?

NMN and NR have already been available in Japan and the U.S. since 2015, and some people have been taking it since then, Imai noted. Anecdotally, I havent heard of any side effects from the taking of these supplements.

Some trials, however, have recorded mild side effects including headaches, nausea, diarrhea and skin flushing.

See: 3 aging experts tell how they decided on where to grow older

More troubling, however, is the conclusion of a 2019 study that showed a possible link between elevated levels of NAD and tumor growth in isolated cells and animals. Rugang Zhang, deputy director at the nonprofit Wistar Institute Cancer Center in Philadelphia, was the lead researcher on that study.The study, published in the UK journal Nature Cell Biology, did not find that NAD causes cancer, rather that elevated levelsappeared to accelerateoncogenesis (tumor formation) already in motion.

We dont want to oversell the results of our study, Zhang said. Lots of studies in the literature have clearly demonstrated that as normal cells age, there is lower NAD. So, supplementing NAD could be beneficial. Its possible that NAD boosters could help people live longer and healthier. Were not saying that if people take NAD boosters they will get cancer. This was a very early study on mouse models, and more study is needed.

He suggests a course of action grounded in a deep preponderance of evidence: At the end of the day, we just need more knowledge, through more research. We need the scientific community to come to a consensus. The risk to potential benefit remains to be seen.

Mucking up the risk/benefit ratio further is the fact that supplements are onlyvery lightly regulatedby the U.S. Food and Drug Administration, with the testing, evaluation and labeling of such products left up to manufacturers. This presents another dilemma for those considering longevity supplements: theres no sure way of knowing exactly what youre getting.

The results of the few published human clinical trials to date unequivocally show that taking NR boosts levels of NAD in the body. But apparently, more NAD doesnt translate to more youthful function.

See: There are six types of retirees which are you?

Unfortunately, those studies have not yet shown any significant efficacy, Imai said.

And thats when the substance administered is of lab-grade purity. So what about the typical supplements available online?

There are so many products out there, Imai lamented, particularly for NMN, but Im concerned about the quality.

Indeed, a 2020meta-analysisof NAD trials surmised: it seems likely that side effects linked to interventions that target NAD metabolism more likely arise from impurities rather than the supplements themselves, since this industry generally operates without rigorous control of quality and standardization.

Imais lab has evaluated a number of commercially available NAD-boosting supplements, but found only two of lab-grade purity. Imai wouldnt disclose the names of the products (both Japanese-made), as he doesnt endorse supplements. But he did note that they are extremely expensive.

Dont miss: What is the secret to aging well?

Finally, we asked someone whod taken an NAD-booster to share her experience. Kim Oberdorfer, an air-traffic controller in Oakland, Calif., wasnt impressed.

I took [a popular NR supplement] for about two months and it just gave me these dull headaches. I was having hot flashes last February, and when I told my sister Im 47, shes 53 about how horrified I was to be having them so young, she goes, Are you sure its not just a reaction to an NAD supplement? said Oberdorfer. At the time I wasnt really working out much, but my sleep schedule was really messed up and I heard it was good for that as well. I didnt think it helped at all.

Rashelle Brownis a longtime fitness professional and freelance writer with hundreds of bylines in print and online. She is a regular contributor for NextAvenue and the Active Network, and is the author of Reboot Your Body: Unlocking the Genetic Secrets to Permanent Weight Loss (Turner Publishing). Connect with her on Twitter and Instagram @RashelleBrownMN.

This article is reprinted by permission fromNextAvenue.org, 2021 Twin Cities Public Television, Inc. All rights reserved.

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What are longevity supplements, and are they safe? - MarketWatch

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Love is Everywhere banners placed in Downtown Boise, ID – boisedev.com

A hopeful message will line the streets of Downtown Boise for the next few months.

After Boise woke up to the news in early December that someone vandalized the Idaho Anne Frank Human Rights Memorial with swastika stickers, Idahoans jumped to action. Amid the outpouring of support, the Downtown Boise Association donated funds to create 50 banners for downtown Anne Frank on them with a simple message: Love is everywhere.

[Micron says racist vandalism & home protests impact our longevity in Idaho; Gov. Little responds]

Our organization represents downtowns and our downtown is for everyone, Downtown Boise Association Executive Director Jennifer Hensley said. When (the vandalism) happened, we felt we needed to join in with the voices saying that really this area is full of love and everyone is welcome here.

This message came in response to the stickers, which said we are everywhere. The vandals stuck them in various places around the memorial, which is one of the few places in the world where the full United Nations Declaration of Human Rights is on display.Police have not announced any arrests in connection to the incident.

[Dozens of business leaders defiantly stand united against vandalism at Frank memorial, call for action]

The banners will be up in downtown Boise for the next few months.

Executive Director of the Wassmuth Center for Human Rights Dan Prinzing, which operates the memorial, said he was overjoyed when Hensleys organization approached him about creating the banners.

As folks see this message, as they read, we also want them to reflect on the message and think about how to put it into practice, he said. How do we live the message?

This one of several high-profile shows of support from Idahos business community since the vandalism. Micron Technology issued a statement condemning the act in a press conference with Boise Mayor Lauren McLean and Prinzing following the discovery of the stickers. Dozens of business leaders also signed a letter in mid-December in support of the memorial and Chobanis founder donated $20,000 to the Wassmuth Center.

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Love is Everywhere banners placed in Downtown Boise, ID - boisedev.com

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