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Category Archives: Genetic Medicine
Study Published In Genetics In Medicine Demonstrates Sequenom CMM MaterniT21 Test Accurately Detects Two Additional …
SAN DIEGO, Feb. 2, 2012 /PRNewswire/ -- Sequenom, Inc. (NASDAQ: SQNM - News), a life sciences company providing innovative genetic analysis solutions, today announced that a new publication of an independent multi-center study on Sequenom Center for Molecular Medicine's MaterniT21™ laboratory-developed test (LDT) appears today in the online issue of Genetics in Medicine. The study demonstrated the LDT can detect fetal trisomy 21, 18 and 13 with high accuracy from a maternal blood sample and will be published in the March issue. The full results of the study can be found online at http://journals.lww.com/geneticsinmedicine/.
"Together with the previously published results on the test's ability to detect trisomy 21 with high accuracy, this publication provides further evidence that this valuable non-invasive technology can identify nearly all cases of T18 and T13, as well as T21, at a low false positive rate," said Harry F. Hixson, Jr., Ph.D., Chairman and CEO, Sequenom, Inc. "This research continues to validate the use of our MaterniT21 LDT as a valuable tool in the care of pregnant women who are at high risk for fetal aneuploidy."
The published results represent a large international, multi-center study conducted at 27 prenatal diagnostic centers. Participating sites collected and processed maternal plasma samples from 4,664 pregnant women at high risk for fetal aneuploidy undergoing diagnostic testing in the late first and early second trimester. The results of a blinded testing of 212 pregnancies with trisomy 21 and their 1,484 matched controls were previously published in Genetics in Medicine. During that same testing period, blinded samples from pregnancies with trisomy 18 and trisomy 13 and their controls were also tested. Inclusion criteria were the same as for the earlier study of trisomy 21.
A total of sixty-two trisomy 18 and twelve trisomy 13 pregnancies along with their matched controls (including the trisomy 21 cases and matched controls) were tested using the MaterniT21 LDT. When unblinded, the detection rate for trisomy 18 was 100 percent and for trisomy 13, was 91.7 percent, with false positive rates of 0.28 and 0.97 percent, respectively.
The research was led by Jacob Canick, PhD, and Glenn Palomaki, PhD, of the Division of Medical Screening and Special Testing in the Department of Pathology and Laboratory Medicine at Women & Infants Hospital and The Warren Alpert Medical School of Brown University, and included scientists at Sequenom Center for Molecular Medicine, San Diego, CA, and an independent academic laboratory at the University of California at Los Angeles. The MaterniT21 test is available exclusively through Sequenom CMM as a testing service to physicians.
An estimated 1,330 cases of trisomy 18 and 600 cases of trisomy 13 are expected at term among the estimated 4.25 million pregnancies in the United States each year.
About Sequenom
Sequenom, Inc. (NASDAQ: SQNM - News) is a life sciences company committed to improving healthcare through revolutionary genetic analysis solutions. Sequenom develops innovative technology, products and diagnostic tests that target and serve discovery and clinical research, and molecular diagnostics markets. The company was founded in 1994 and is headquartered in San Diego, California. Sequenom maintains a Web site at http://www.sequenom.com to which Sequenom regularly posts copies of its press releases as well as additional information about Sequenom. Interested persons can subscribe on the Sequenom Web site to email alerts or RSS feeds that are sent automatically when Sequenom issues press releases, files its reports with the Securities and Exchange Commission or posts certain other information to the Web site.
About Sequenom CMM
Sequenom Center for Molecular Medicine® (Sequenom CMM), a CAP accredited and CLIA-certified molecular diagnostics laboratory, is developing a broad range of diagnostics with a focus on prenatal diseases and conditions. These laboratory-developed tests provide beneficial patient management options for obstetricians, geneticists and maternal fetal medicine specialists. Sequenom CMM is changing the landscape in genetic disorder diagnostics using proprietary cutting edge technologies.
Forward-Looking Statement
Except for the historical information contained herein, the matters set forth in this press release, including statements regarding the use of the MaterniT21 test as a valuable tool in the care of pregnant women, expectations regarding the future performance, utility, and impact of the test, the Company's commitment to improving healthcare through revolutionary genetic analysis solutions, and Sequenom CMM changing the landscape in genetic disorder diagnostics, are forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially, including the risks and uncertainties associated with market demand for and acceptance and use by customers of new tests such as the MaterniT21 LDT, reliance upon the collaborative efforts of other parties, the Company's financial position, its ability to position itself for product launches and growth and develop and commercialize new technologies and products, particularly new technologies such as noninvasive prenatal diagnostics, laboratory developed tests, and genetic analysis platforms, the Company's ability to manage its existing cash resources or raise additional cash resources, competition, intellectual property protection and intellectual property rights of others, government regulation particularly with respect to diagnostic products and laboratory developed tests, obtaining or maintaining regulatory approvals, litigation involving the Company, and other risks detailed from time to time in the Company's most recently filed Quarterly Report on Form 10-Q and Annual Report on Form 10-K for the year ended December 31, 2010, and other documents subsequently filed with or furnished to the Securities and Exchange Commission. These forward-looking statements are based on current information that may change and you are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this press release. All forward-looking statements are qualified in their entirety by this cautionary statement, and the Company undertakes no obligation to revise or update any forward-looking statement to reflect events or circumstances after the issuance of this press release.
(Logo: http://photos.prnewswire.com/prnh/20040415/SQNMLOGO)
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Study Published In Genetics In Medicine Demonstrates Sequenom CMM MaterniT21 Test Accurately Detects Two Additional ...
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Workshop 2: Fundamentals of Genetic Testing Part I – Selena Martinez – Video
02-11-2011 12:51 Selena shares her family's experience with Lynch syndrome. This workshop is part of a genomics curriculum for practicing healthcare providers developed by the Genomic Medicine Institute at El Camino Hospital, Genetic Alliance, and the National Coalition for Health Professional Education in Genetics. This workshop, the second in a 10-part series, covered genetic-testing technology; selecting appropriate genetic tests; ordering tests; pre- and post-test counseling; test costs; interpreting test results.
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Workshop 2: Fundamentals of Genetic Testing Part I - Selena Martinez - Video
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The Reality of Race – Video
26-01-2012 09:21 Jared Taylor, editor of American Renaissance, explains the biological basis of race. Sources: Weiss, Rick, and Justin Gillis. "Teams Finish Mapping Human DNA." Washington Post 27 June 2000: A1. Print. Edwards, AWF "Human Genetic Diversity: Lewontin's Fallacy." BioEssays 25.8 (2003): 798-801. Web. http://www.goodrumj.com Lewontin, Richard C. "The Apportionment of Human Diversity." Evolutionary Biology 6 (1972): 391-98. Print. Risch, Niel J. et al. "Genetic Structure, Self-Identified Race/Ethnicity, and Confounding in Case-Control Association Studies." American Journal of Human Genetics 76.2 (2005): 268-75. Web. http://www.ncbi.nlm.nih.gov Ousley, Stephen D. "Understanding Race and Human Variation: Why Forensic Anthropologists Are Good at Identifying Race." American Journal of Physical Anthropology 139 (2009): 68-76. Web. onlinelibrary.wiley.com Sauer, Norman J. "Forensic Anthropology and the Concept of Race: If Races Don't Exist, Why Are Forensic Anthropologists So Good at Identifying Them?" Social Science Medicine 34.2 (1992): 107-11. Print. Norton, Cherry. "Hidden Black Ancestry Linked to Rise in Sickle Cell Blood Disorder." Independent. 23 Oct. 1999. Web. http://www.independent.co.uk Motulsky, Arno G. "Frequency of Sickling Disorders in US Blacks." New England Journal of Medicine 288 (1973): 31-33. Print. "Hemochromatosis." PubMed Health. 12 Apr. 2010. Web. http://www.ncbi.nlm.nih.gov Parker, Heidi G et al. "Genetic Structure of the Purebred Domestic Dog." Science 304 (2004): 1160-164. Print ...
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The Reality of Race - Video
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Damnit I’m A Doctor Not A TSA Agent (Brainstorm Ep43) – Video
30-01-2012 09:19 Website qdragon.info Shirts and Stuff http://www.zazzle.com My twitter twitter.com Like Brainstorm on Facebook http://www.facebook.com Technology News tinyurl.com Medical News tinyurl.com Biotechnology News tinyurl.com Hosted by http://www.youtube.com Contributors http://www.youtube.com http://www.youtube.com RNA Video http://www.youtube.com
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Damnit I'm A Doctor Not A TSA Agent (Brainstorm Ep43) - Video
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Genetic Technologies Posts $1.6M in Revenues in Q2
Saladax Biomedical said today that President and CEO Edward Erickson has resigned due to personal and family reasons, and that he will be replaced by Kevin Harter on an interim basis. Erickson will remain a member of the company's board of directors. Harter is a co-founder and senior VP of the Life Sciences Greenhouse, and he has served as executive chairman at Saladax.
Helicos Biosciences has elected Bruce Ginsberg to its board of directors to review certain financing matters. Ginsberg is president and CEO of MooBella, a food service provider, and a member of the board of directors of Mac-Gray.
Life Technologies VP of Research and Development Manohar Furtado has been appointed to serve as an advisor on the National Biodefense Science Board, a federal advisory committee for the Department of Health and Human Services. The board provides advice on bioterrorism and other public health emergencies. Furtado was appointed to serve a four-year term on the board. Kevin Jarrell, CEO of Modular Genetics, also will continue to serve on the board.
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Genetic Technologies Posts $1.6M in Revenues in Q2
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Miracle Cure A Decade of the Human Genome – BBC Horizon (HD). 720p – Video
11-12-2011 09:20 A decade ago, scientists announced that they had produced the first draft of the human genome, the 3.6 billion letters of our genetic code. It was seen as one of the greatest scientific achievements of our age, a breakthrough that would usher in a new age of medicine. A decade later, Horizon finds out how close we are to developing the life-changing treatments that were hoped for. Horizon follows three people, each with a genetic disease, as they go behind the scenes at some of Britain's leading research labs to find out what the sequencing of the human genome has done for them - and the hope this remarkable project offers all of us.
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Miracle Cure A Decade of the Human Genome - BBC Horizon (HD). 720p - Video
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