Category Archives: Chemistry

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Rodents feeding on sweet mignonette love the fruit, but dislike the spicy seeds. So they spit them out, thereby dispersing them--to the plant's benefit. Karen Hopkin reports.

June 14, 2012

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How does a Venus flytrap know when to snap shut? Can it actually feel an insects tiny, spindly legs? And how do cherry blossoms know when to bloom? Can they...

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Plants that use animals to disperse their seeds can find themselves in a pickle. They need to make fruit tasty enough to entice the local fauna. But they also need to make sure that their animal assistants dont digest the very seeds theyre meant to spread.

In Israels Negev Desert, a plant called sweet mignonette came up with a distasteful strategy. Critters called spiny mice feed on mignonette. They love the fruit. But they hate the seeds. And so they spit them out all over the place. Just as the plant planned. Thats according to a study in the journal Current Biology. [Michal Samuni-Blank et al, Intraspecific Directed Deterrence by the Mustard Oil Bomb in a Desert Plant]

Sweet mignonette produces little black berries that house about 20 seeds apiece. Inside those seeds is an enzyme. When a berry-chomping mouse crushes a seed, the enzyme is freed up to produce compounds that taste like hot mustard. Hence, ptooey, better leaving through chemistry.

Excerpt from:
Plant's Chemistry Gets Mice To Spit Seeds

Ward Hill, MA - Alfa Aesar, a Johnson Matthey Company, is pleased to announce the addition of a variety of compounds for use in click chemistry reactions to its expanding range of bio products.

Click chemistry is a newer approach to synthesis that makes use of simple, rapid and reliable reactions. It has several benefits over other synthesis approaches such as being orthogonal to conventional methods and occurring under relatively mild conditions. These reactions also proceed with high, almost quantitative, yields. These benefits have made click chemistry reactions a popular method of introducing labels and other tags to biomolecules. The most popular click chemistry reaction is the Huisgen 1,3-dipolar cycloaddition of alkynes to azides, which is generally carried out with catalysis by copper (I), or by introduction of an azide to a strain-promoted cyclooctyne.

Alfa Aesar's click chemistry product range offers bifunctional linkers, fluorescent tags and chemical modifications that can be used with the azide-alkyne click chemistry technique.

To request a product flyer on these products or for a free copy of the full Bio product catalog, contact Alfa Aesar at 1-800-343-0660 or email info@alfa.com.

About Alfa Aesar Alfa Aesar, a Johnson Matthey Company, is a leading international manufacturer and supplier of research chemicals, metals and materials. With over 36,000 products listed in its catalogs, Alfa Aesar is the single source for customers' needs for chemicals and materials in sizes for research and scale up. The Alfa Aesar catalog carries materials for biological research, organic compounds, high purity inorganics, pure elements, alloys, precious metal catalysts, AA/ICP standards and more. Alfa Aesar has sales offices and distribution facilities throughout North America, Europe and Asia and a distributor network covering the globe.

Contact: Mara Nieuwsma Alfa Aesar, A Johnson Matthey Company Tel. 1-978-521-6414 Fax 1-978-521-6350 Email mara.nieuwsma@alfa.com http://www.alfa.com

Original post:
Click Chemistry Reagents Now Available from Alfa Aesar

Chevron Corporation is one of the world's leading integrated energy companies with subsidiaries that conduct business across the globe. The company's success is driven by the ingenuity and commitment of approximately 62,000 employees who operate across the energy spectrum. Chevron explores for, produces and transports crude oil and natural gas; refines, markets and distributes transportation fuels and other energy products and services; manufactures and sells petrochemical products; generates power and produces geothermal energy; and develops and commercializes the energy resources of the future, including biofuels and other renewables. Chevron is based in San Ramon, California.

Chevron Energy Technology Company is accepting online applications for the position of Production Chemistry Management Specialist located in Houston, TX.

Overview:

This position will have responsibilities for monitoring, diagnosing and treating oilfield production problems, developing and optimizing chemical treatment programs, and working closely with operating assets and chemical service company personnel. This position will be based in Houston, Texas and will report to head of the Production Chemistry Team.

Responsibilities for this position may include but are not limited to:

Provides technical support for major capital projects by developing recommendations for fluid sampling, fluid and chemical analyses, and chemical treating and performance monitoring as part of the system design and development

Provides guidance to both capital projects and existing fields on the selection and qualification of production chemicals. This includes recommending appropriate test methodologies/protocols and providing oversight of chemical vendors' chemical selection process

Provides consultation to operating assets in diagnosing chemical related issues and providing reliable and cost-effective chemical solutions

Works with operating assets and chemical vendors to develop chemical management programs, and optimize chemical treatments and performance monitoring

Develops proposals for funding from operating assets/business units

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Production Chemistry Management Specialist

Public release date: 14-Jun-2012 [ | E-mail | Share ]

Contact: Joan Coyle J_coyle@acs.org 202-872-6229 American Chemical Society

WASHINGTON The American Chemical Society's (ACS') 16th annual Green Chemistry & Engineering (GC&E) Conference takes place June 18-20 at the Marriott Wardman Park Hotel in Washington, D.C. This year's theme is Innovation, Jobs, Sustainability The Role of Green Chemistry.

Media registration for the GC&E Conference is complimentary for credentialed members of the news media. Media registrants have access to the breakfasts, education sessions, keynote speakers, sponsors' luncheon, exhibition, press room and opening-night reception. For complete media registration guidelines, please contact ACS GCI at 202-872-6022 or Shefali Algoo at s_algoo@acs.org.

On-site registration: Media wishing to register on-site must present valid, current media credentials (e.g., official picture identification from the employing news organization, signed letter from assignment editor on company letterhead or a bylined article from the publication). Without proper, approved credentials, on-site media registration will be denied. Marketing and public relations executives, analysts, consultants, authors and researchers may not register as media.

Press briefings will be held in the Marriott's Jefferson Room. Media can also participate via live webcast, or they can view the archive later at the same site.

Tuesday, June 19, Morning Press Briefings: Innovation, Jobs, Sustainability The Role of Green Chemistry

Tuesday, June 19, Afternoon Press Briefings: Innovation, Jobs, Sustainability The Role of Green Chemistry

Wednesday, June 20, Afternoon Press Briefings: Innovation, Jobs, Sustainability The Role of Green Chemistry

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Green Chemistry and Engineering Conference press events

SAN FRANCISCO, June 14, 2012 /PRNewswire/ --Sutro Biopharma today announced that it has signed a licensing agreement with The Scripps Research Institute and will have access to "click chemistry," a modular synthetic approach that allows the assembly of new molecular entities by efficiently and reliably joining two molecular units together stably and irreversibly. The agreement with Scripps Research provides Sutro with a worldwide license to apply click chemistry for the synthesis of novel therapeutic protein candidates by utilizing Sutro's biochemical protein synthesis platform to incorporate one or more of the "click" components into a peptide or protein chain.

The click chemistry approach was developed by Nobel Laureate K. Barry Sharpless, Ph.D., the W.M. Keck professor of chemistry at The Scripps Research Institute, and describes synthetic chemistry tailored to generate substances. This is done by joining, or clicking, reactive molecular building blocks together selectively and covalently. Click chemistry allows the further design of different types of therapeutic agents, including antibody therapeutics, peptide therapeutics and various small molecules.

"Combined with Sutro's powerful platform, 'click chemistry' will further extend our capability to engineer customized therapeutics with pharmacologic properties that are optimized for each specific application," said Trevor Hallam, Ph.D., chief scientific officer of Sutro. "The agreement will expand our armamentarium as we continue to develop novel protein therapeutics with our partners and advance our own pipeline of next-generation antibody drug conjugates."

The financial terms of the agreement were not disclosed.

About The Scripps Research Institute

The Scripps Research Institute is one of the world's largest independent, not-for-profit organizations focusing on research in the biomedical sciences. Over the past decades, Scripps Research has developed a lengthy track record of major contributions to science and health, including laying the foundation for new treatments for cancer, rheumatoid arthritis, hemophilia, and other diseases. The institute employs about 3,000 people on its campuses in La Jolla, CA, and Jupiter, FL, where its renowned scientists -- including three Nobel laureates -- work toward their next discoveries. The institute's graduate program, which awards Ph.D. degrees in biology and chemistry, ranks among the top ten of its kind in the nation. For more information, see http://www.scripps.edu

About Sutro Biopharma

Sutro Biopharma, located in South San Francisco, is developing anew generation of antibody drug conjugate therapeutics and bifunctional antibody-based therapeutics for targeted cancer therapies. These therapeutics will significantly extend the clinical impact of current oncology therapeutic approaches and are beyond what can be envisioned with current (cell-based) expression technologies. Sutro's biochemical synthesis technology, which underpins these therapeutics, allowsthe rapid and systematic exploration of many protein drug variants to identify drug candidates. Our make-test cycle for hundreds of protein variants, including those incorporating non-natural amino acids, takes approximately two weeks.Once these product candidates are identified, production can be rapidly and predictably scaled up to commercial levels. In addition to developing its own drug pipeline, Sutro Biopharma is collaborating with select pharmaceutical and biotech companies in the discovery and development of novel protein therapeutics. For more information, visit http://www.sutrobio.com.

Media Contacts:

David Schull or Martina Schwarzkopf, Ph.D. Russo Partners (212) 845-4271 (212) 845-4292 (347) 591-8785 (mobile) david.schull@russopartnersllc.com martina.schwarzkopf@russopartnersllc.com

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Sutro Licenses "Click Chemistry" from The Scripps Research Institute

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FIFA 12: Exploring The Individual Player Chemistry Myth - Video