Category Archives: Biotechnology

B.R.A.I.N. Biotechnology Research and Information Network AG (ETR:BNN) is possibly approaching a major achievement in its business, so we would like to shine some light on the company. B.R.A.I.N. Biotechnology Research and Information Network AG researches, develops, produces, and markets enzymes, biocatalysts, microorganisms, and bioactive natural substances for chemical and consumer goods industries in Germany, the United States, France, and the United Kingdom. The 166m market-cap company announced a latest loss of 9.7m on 30 September 2020 for its most recent financial year result. The most pressing concern for investors is B.R.A.I.N. Biotechnology Research and Information Network's path to profitability when will it breakeven? In this article, we will touch on the expectations for the company's growth and when analysts expect it to become profitable.

View our latest analysis for B.R.A.I.N. Biotechnology Research and Information Network

B.R.A.I.N. Biotechnology Research and Information Network is bordering on breakeven, according to the 6 German Chemicals analysts. They anticipate the company to incur a final loss in 2022, before generating positive profits of 236k in 2023. The company is therefore projected to breakeven around 2 years from now. What rate will the company have to grow year-on-year in order to breakeven on this date? Using a line of best fit, we calculated an average annual growth rate of 100%, which is extremely buoyant. Should the business grow at a slower rate, it will become profitable at a later date than expected.

Given this is a high-level overview, we wont go into details of B.R.A.I.N. Biotechnology Research and Information Network's upcoming projects, however, take into account that typically a high growth rate is not out of the ordinary, particularly when a company is in a period of investment.

Before we wrap up, theres one aspect worth mentioning. The company has managed its capital judiciously, with debt making up 21% of equity. This means that it has predominantly funded its operations from equity capital, and its low debt obligation reduces the risk around investing in the loss-making company.

This article is not intended to be a comprehensive analysis on B.R.A.I.N. Biotechnology Research and Information Network, so if you are interested in understanding the company at a deeper level, take a look at B.R.A.I.N. Biotechnology Research and Information Network's company page on Simply Wall St. We've also compiled a list of key factors you should look at:

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This article by Simply Wall St is general in nature. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned. *Interactive Brokers Rated Lowest Cost Broker by StockBrokers.com Annual Online Review 2020

Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) simplywallst.com.

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When Will B.R.A.I.N. Biotechnology Research and Information Network AG (ETR:BNN) Breakeven? - Simply Wall St

LOS ANGELES--(BUSINESS WIRE)--Puma Biotechnology, Inc. (NASDAQ: PBYI), a biopharmaceutical company, announced interim results from the biliary tract cancers cohort of the ongoing SUMMIT trial of neratinib at the virtual 2021 Gastrointestinal Cancers Symposium hosted by the American Society of Clinical Oncology (ASCO GI) that is currently taking place. The presentation, entitled, Targeting HER2 (ERBB2) mutation-positive advanced biliary tract cancers with neratinib: Results from the phase II SUMMIT basket trial, is being presented at a Poster Session by James J. Harding, MD, Regional Director, Early Drug Development, Memorial Sloan Kettering Cancer Center, an investigator of the trial. A copy of this poster presentation is available on the Puma website.

The Phase II SUMMIT basket trial is an open-label, multicenter, multinational study that included a cohort evaluating the safety and efficacy of neratinib administered daily to patients who have HER2 (ERBB2) mutation-positive advanced biliary cancer. Patients received 240 mg of neratinib daily as a single agent.

In this cohort of 25 patients, 11 patients had cholangiocarcinoma, 10 patients had cancer of the gallbladder and 4 patients had cancer of the ampulla of Vater. 24 patients had received prior systemic chemotherapy with a median of 2 prior lines of therapy (range 0-7) before entering the trial.

The efficacy results from the trial demonstrated that there were 4 patients with confirmed partial responses (3 patients with cancer of the gallbladder and 1 patient with cholangiocarcinoma) and an additional 3 patients who had stable disease lasting 16 weeks (1 patient with cancer of the ampulla of Vater and 2 patients with cholangiocarcinoma, one of which remained on treatment for 56 weeks before progression). This resulted in an objective response rate of 16% and a clinical benefit rate of 28%. The durations of response were 3.0 months, 3.7 months, and 4.7 months and additionally one patient with gallbladder cancer remains on treatment >80 weeks.

The safety profile of patients with biliary tract tumors is similar to that previously reported for patients treated with neratinib monotherapy and mandatory loperamide prophylaxis in the first 2 months; treatment was manageable, with 56% of patients experiencing some diarrhea, including 24% with grade 3 diarrhea. There were no episodes of grade 4 diarrhea, and no treatment discontinuations due to diarrhea. Four patients required neratinib dose reduction and one patient was hospitalized due to diarrhea.

We have shown neratinib to be safe and tolerable in these patients with advanced biliary tract tumors, and demonstrated activity comparable to current standards of care with similar progression-free survival and overall survival in these heavily pretreated patients, said Dr. Harding.

Alan H. Auerbach, CEO and President of Puma Biotechnology, added, We are very pleased with the preliminary activity seen with neratinib in this cohort of patients and specifically in patients with cancer of the gallbladder and cholangiocarcinoma.

About Puma Biotechnology

Puma Biotechnology, Inc. is a biopharmaceutical company with a focus on the development and commercialization of innovative products to enhance cancer care. Puma in-licenses the global development and commercialization rights to PB272 (neratinib, oral), PB272 (neratinib, intravenous) and PB357. Neratinib, oral was approved by the U.S. Food and Drug Administration in 2017 for the extended adjuvant treatment of adult patients with early stage HER2-overexpressed/amplified breast cancer, following adjuvant trastuzumab-based therapy, and is marketed in the United States as NERLYNX (neratinib) tablets. In February 2020, NERLYNX was also approved by the FDA in combination with capecitabine for the treatment of adult patients with advanced or metastatic HER2-positive breast cancer who have received two or more prior anti-HER2-based regimens in the metastatic setting. NERLYNX was granted marketing authorization by the European Commission in 2018 for the extended adjuvant treatment of adult patients with early stage hormone receptor-positive HER2-overexpressed/amplified breast cancer and who are less than one year from completion of prior adjuvant trastuzumab-based therapy. NERLYNX is a registered trademark of Puma Biotechnology, Inc.

Further information about Puma Biotechnology may be found at http://www.pumabiotechnology.com.

IMPORTANT SAFETY INFORMATION

NERLYNX (neratinib) tablets, for oral use

INDICATIONS AND USAGE: NERLYNX is a kinase inhibitor indicated:

CONTRAINDICATIONS: None

WARNINGS AND PRECAUTIONS:

ADVERSE REACTIONS:

The most common adverse reactions (reported in 5% of patients) were as follows:

To report SUSPECTED ADVERSE REACTIONS, contact Puma Biotechnology, Inc. at 1-844-NERLYNX (1-844-637-5969) or FDA at 1-800-FDA-1088 or http://www.fda.gov/medwatch.

DRUG INTERACTIONS:

USE IN SPECIFIC POPULATIONS:

Lactation: Advise women not to breastfeed.

Please see Full Prescribing Information for additional safety information.

To help ensure patients have access to NERLYNX, Puma has implemented the Puma Patient Lynx support program to assist patients and healthcare providers with reimbursement support and referrals to resources that can help with financial assistance. More information on the Puma Patient Lynx program can be found at http://www.NERLYNX.com or 1-855-816-5421.

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Puma Biotechnology Presents Interim Results from the Biliary Tract Cancers Cohort of the Phase II SUMMIT Basket Trial of Neratinib at ASCO GI -...

GlobalInterferons (IFNs)Market Report available at Index Markets Research provides a roadmap of the Interferons (IFNs) industry which makes up for the scope of product, market revenue cycle, new opportunities, CAGR, sales volumes, and figures. It includes Porters Five Forces and PESTLE analysis to equip your business with critical information and comparative data about the Global Interferons (IFNs) Market. We have provided deep analysis of the vendor landscape to give you a complete picture of current and future competitive scenarios of the global Interferons (IFNs) market. Our analysts use the latest primary and secondary research techniques and tools to prepare comprehensive and accurate market research reports.

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View Exhaustive Market Research Report @https://www.indexmarketsresearch.com/report/global-interferons-ifns-market-3/459091/

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Customization of the Report:1)All segmentation provided above in this report is represented at country level.2)All products covered in the market, product volume and average selling prices will be included as customizable options which may acquire no or minimal additional cost (depends on customization).

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Global Interferons (IFNs) Market 2021-2025 | Evolving Opportunities with Roche, Anke Biotechnology, Bayer, Merck & Co, Tri-Prime - KSU | The...

The 62 rating InvestorsObserver gives to Dare Bioscience Inc (DARE) stock puts it near the top of the Biotechnology industry. In addition to scoring higher than 77 percent of stocks in the Biotechnology industry, DAREs 62 overall rating means the stock scores better than 62 percent of all stocks.

Finding the best stocks can be tricky. It isnt easy to compare companies across industries. Even companies that have relatively similar businesses can be tricky to compare sometimes. InvestorsObservers tools allow a top-down approach that lets you pick a metric, find the top sector and industry and then find the top stocks in that sector.

Our proprietary scoring system captures technical factors, fundamental analysis and the opinions of analysts on Wall Street. This makes InvestorsObservers overall rating a great way to get started, regardless of your investing style. Percentile-ranked scores are also easy to understand. A score of 100 is the top and a 0 is the bottom. Theres no need to try to remember what is good for a bunch of complicated ratios, just pay attention to which numbers are the highest.

Dare Bioscience Inc (DARE) stock is trading at $2.34 as of 1:25 PM on Tuesday, Jan 19, a gain of $0.90, or 62.5% from the previous closing price of $1.44. The stock has traded between $1.41 and $2.68 so far today. Volume today is high. So far 26,044,216 shares have traded compared to average volume of 1,477,335 shares.

Click Here to get the full Stock Score Report on Dare Bioscience Inc (DARE) Stock.

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Is Dare Bioscience Inc (DARE) The Right Choice in Biotechnology? - InvestorsObserver

New investments include companies focused on Oncology, Rare Disease, and Inflammation & Immunology

Pfizer Inc has announced that, during the second half of 2020, it invested a total of $120 million in four clinical-stage biotech companies as part of thePfizer Breakthrough Growth Initiative(PBGI).

Through PBGI, Pfizer is investing up to $500 million in biotechnology companies, providing funding and access to Pfizers scientific expertise to help ensure the continuity of promising clinical development programmes of potential future strategic interest to Pfizer.

Established in June 2020, the Pfizer Breakthrough Growth Initiative focuses on non-controlling equity investments primarily in public companies with small- to medium-sized market capitalisations and mature private companies that are developing clinical-stage assets aligned with Pfizers core areas of focus: Internal Medicine, Inflammation & Immunology, Oncology, Rare Disease, Vaccines, and Hospital.

Pfizers initial PBGI investments include:

Debbie Baron, Senior Vice President, Business Development, Pfizer said, Our investments in Homology, Vedanta, Trillium, and ESSA reflect our commitment to find new and creative ways to leverage Pfizers resources to deliver breakthroughs to patients.

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Pfizer to invest $500 M in biotechnology companies - BSA bureau

Fort Collins, Colorado: Reports Globe has published the latest study on Pharmaceutical and Biotechnology Machines Market Report Analysis by Size with Future Outlook, Key Players SWOT Analysis and Forecast to 2026. It uses exploratory techniques such as qualitative and quantitative analysis to identify and present data on the target market. Successful sales strategies have been mentioned that will help you do business in record time and multiply customers.

This report is presented clearly and concisely to help you better understand the structure and dynamics of the market. The trends and recent developments in the Pharmaceutical and Biotechnology Machines market were analyzed. The opportunities that lead to the growth of the market were analyzed and presented. Focusing on the global market, the report provides answers to the key questions stakeholders are facing today around the world. Information on market size raises the problem of increasing competitiveness and hampering market-leading sectors and market growth.

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Some of the Important and Key Players of the Global Pharmaceutical and Biotechnology Machines Market:

Pharmaceutical and Biotechnology Machines market research report provides detailed information on the following aspects: Industry Size, Market Share, Growth, Segmentation, Manufacturers and Advancement, Key Trends, Market Drivers, Challenges, Standardization, Deployment Models, Opportunities, Strategies, Future Roadmaps and Annual Forecasts to 2027, etc. The report will help you also in understanding the dynamic structure of the Pharmaceutical and Biotechnology Machines market by identifying and analyzing market segments. The Global Pharmaceutical and Biotechnology Machines 2021 Industry Research Report has given the expected compound annual growth rate (CAGR) as a% of value for a given period of time and clearly helps the user make their decision based on the futuristic chart of the key players on the global Pharmaceutical and Biotechnology Machines market. The report introduces some of the major players in the global Pharmaceutical and Biotechnology Machines market and offers insightful information about the Pharmaceutical and Biotechnology Machines industry such as Business Overview, Pharmaceutical and Biotechnology Machines Market Product Segmentation, Revenue Segmentation, and the Latest Information. Developments.

Additionally, the Pharmaceutical and Biotechnology Machines market report includes a comprehensive strategic review as well as summarized studies of the growth, key factors, and market opportunity by which to evaluate the Pharmaceutical and Biotechnology Machines market and other important market related details on Pharmaceutical and Biotechnology Machines. The investigation of the research report also helps uncover accurate industry statistics depicting the ultimate model of the global Pharmaceutical and Biotechnology Machines market, including various types, applications, market growth structures, and opportunities. In addition, the study of the market research report provides an investigation and analysis of the past and current performance of the regional market that includes regions by department and subdivision. This regional analysis studies various key market parameters such as Pharmaceutical and Biotechnology Machines market growth rate in each region, production volume and capacity, market demand and supply, and return on investment (RoI).

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Some of the key questions answered in the report include-

1. What is the overall structure of the market?2. What was the historical value and what is the forecasted value of the market?3. What are the key product level trends in the market?4. What are the market level trends in the market?5. Which of the market players are leading and what are their key differential strategies to retain their stronghold?6. Which are the most lucrative regions in the market space?

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Global Pharmaceutical and Biotechnology Machines market is segmented based by type, application and region.

Pharmaceutical and Biotechnology Machines Market Segmentation, By Type

Pharmaceutical and Biotechnology Machines Market Segmentation, By Application

The prime objective of this report is to help the user understand the market in terms of its definition, segmentation, market potential, influential trends, and the challenges that the market is facing. Deep researches and analysis were done during the preparation of the report. The readers will find this report very helpful in understanding the market in depth. The data and the information regarding the market are taken from reliable sources such as websites, annual reports of the companies, journals, and others and were checked and validated by the industry experts. The facts and data are represented in the report using diagrams, graphs, pie charts, and other pictorial representations. This enhances the visual representation and also helps in understanding the facts much better.

Global Pharmaceutical and Biotechnology Machinesmarket Key Report Highlights:

This in-depth research documentation offers an illustrative overview of the entire market outlook with details on scope, executive summary, and market segments The report also includes sections on the competitive spectrum, highlighting major players, with a detailed assessment of supply chain management, competition dynamics, and growth objectives. Other crucial details on Porters Five Forces assessment, SWOT analysis, and data triangulation methods have also been included in the report. Other relevant details on production patterns, growth rate, market share of each of the segments have also been pinned in the report. The report also houses crucial analytical details on revenue share and sales projections, besides volumetric estimations of each of the product segments have also been highlighted in the report to encourage unfaltering market decisions and sustainable revenue streams in the global Pharmaceutical and Biotechnology Machines market.A dedicated chapter on COVID-19 analysis has therefore been included in this versatile report to encourage future-ready business discretion aligning with post-COVID-19 market environment.

Major Points from Table of Content:

1. Executive Summary2. Assumptions and Acronyms Used3. Research Methodology4. Pharmaceutical and Biotechnology Machines Market Overview5. Pharmaceutical and Biotechnology Machines Supply Chain Analysis6. Pharmaceutical and Biotechnology Machines Pricing Analysis7. Global Pharmaceutical and Biotechnology Machines Market Analysis and Forecast by Type8. Global Pharmaceutical and Biotechnology Machines Market Analysis and Forecast by Application9. Global Pharmaceutical and Biotechnology Machines Market Analysis and Forecast by Sales Channel10. Global Pharmaceutical and Biotechnology Machines Market Analysis and Forecast by Region11. North America Pharmaceutical and Biotechnology Machines Market Analysis and Forecast12. Latin America Pharmaceutical and Biotechnology Machines Market Analysis and Forecast13. Europe Pharmaceutical and Biotechnology Machines Market Analysis and Forecast14. Asia Pacific Pharmaceutical and Biotechnology Machines Market Analysis and Forecast15. Middle East & Africa Pharmaceutical and Biotechnology Machines Market Analysis and Forecast16. Competition Landscape

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Pharmaceutical and Biotechnology Machines Market Size By Analysis, Key Vendors, Regions, Type and Application, and Forecasts to 2027 - NeighborWebSJ