Category Archives: Anti-Aging Medicine

A recent observational study examined the links between markers of heart health and 3 types of diets and concluded that plant based diets which are rich in fruits and vegetables are associated with better heart health.

The three types of diets were : a typical Western diet, the DASH diet, and a fruit and vegetable rich diet. The DASH diet was developed by nutritional specialists affiliated with NIH, and on the whole it favors intake of low fat dairy, whole grains, fruits, vegetables, nuts, beans, fish, and poultry over red meats and fatty, sugary, or salty foods.

Findings from this study were published in the Annals of Internal Medicine, and the analysis draws on data from the Dietary Approaches to Stop Hypertension Trial that assessed effects of specially designed diets on blood pressure in comparison to other types of diets.

Data was analyzed from three randomly assigned groups of participants from the DASH trials involving 326 participants that had followed one of the three diets for a period of 8 weeks. Mean age was 54.2 years, and none of the participants had preexisting cardiovascular conditions.

Participants' serum samples were collected after a 12 hours fast before the study started and then again at the end of the 8 week study period. Serum biomarkers that were assessed included: high sensitivity cardiac troponin 1, N-terminal pro-B-type natriuretic peptide, and high sensitivity C-reactive protein.

Troponin helps to regulate contractions of heart muscle, elevated levels can indicate heart damage. Elevated levels of C-reactive protein can indicate inflammation, and elevated levels of pro-B-type natriuretic peptides can be a marker of heart failure.

Those who followed the DASH diet or the fruit/veggies rich diet were found to have had significantly lower concentrations of the biomarkers troponin and pro-B-type natriuretic peptide than those following a typical American diet after assessing both sets of serum samples.

The researchers suggest that their findings indicate better heart health in those two groups, and that the levels of the biomarkers did not differ among those who had followed either of the plant based rich diets. However, levels of C-reactive protein were not affected by any of the three diets.

It is not clear which aspects of the plant based diets may have benefited heart health. The authors write: Our study suggests that dietary features common to both the DASH and fruit-and-vegetable diets, including but not limited to higher potassium, magnesium, and fiber content, may be causative factors. Further research is needed to confirm whether similar diets can improve cardiac function in adults with established heart failure.

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Produce Rich Diets Tied To Better Heart Health - Anti Aging News

Johns Hopkins Professor Explains New Research on Protecting the Most Vulnerable

MELBOURNE, FLA. A medical doctor and researcher at Johns Hopkins University who leads human cardiovascular studies at the Laboratory of Cardiovascular Science at National Institutes of Healths National Institute on Aging will explore the intersection of aging, heart disease and COVID-19 during a free virtual workshop from 1-2:30 p.m. Monday, June 1, organized and hosted by Florida Tech.

Dr. Majd AlGhatrif will discuss why older adults with underlying cardiovascular disease are experiencing increased disease severity and higher mortality rates from COVID-19. These possible connections were highlighted in an April article in the Journal of the American Medical Associations JAMA Cardiology byAlGhatrif and Edward G. Lakatta, both of the Laboratory of Cardiovascular Science in NIAs Intramural Research Program, and Oscar Cingolani of the Johns Hopkins School of Medicine.

In their article, the authors propose that using blockers for hormones called angiotensin that affect blood pressure may prevent severe COVID-19, particularly in older adults with low baseline levels of a key anti-inflammatory factor called angiotensin converting enzyme 2, or ACE2. However, this hypothesis needs to be tested in clinical trials with people who have COVID-19 to determine the safety and efficacy of these medications in reducing the risk of developing severe lung disease, they note.

In addition to AlGhatrifs presentation and question-and-answer segment, the event will feature short presentations about several efforts undertaken at Florida Tech in response to the pandemic. Those scheduled to present are:

Marco Carvalho, Ph.D., Florida Techs executive vice president for academics, will offer opening remarks.

To participate online, visit https://fit.zoom.us/j/95454967579.

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Virtual Event June 1 Explores Aging, Heart Disease and COVID-19 - Florida Tech Now

This report studies the Anti-Aging Drugs Market with many aspects of the industry like the market size, market status, market trends and forecast, the report also provides brief information of the competitors and the specific growth opportunities with key market drivers. Find the complete Anti-Aging Drugs Market analysis segmented by companies, region, type and applications in the report.

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2020-2026 Anti-Aging Drugs Market Research by Manufacturers, Regions, Types and Applications - News Distinct

Dominique Fradin-Read is the doctor who has achieved that Adele has lost weight over 70 kilos in the last few months. A radical change which, until now, prevented millions of people from all over the world guessing, as no one knew how it had been accomplished. Now, the doctor has revealed to you what is your trick to slimming down and has made it clear that this is not sport.

The artist is unrecognizable after undergoing a slimming process in which your doctor, based in Los Angeles, has had much to do. Fradin-Read has shared the secret that you use with all their clients, insisting that it is not only exercise, but the process has a lot to do with the mood and mental health.

EC

The products are high in saturated fats or refined carbohydrates, and add a lot of calories may boycott our plan to lose weight

Dominique Fradin-Read has explained to US Weekly weight loss is not just exercisebut the sport should be a part of a transformation of the broader lifestyle of the person. That is why, ensures that the mental health and well-being of those who want to lose weight are just as important as the diet and physical exercise.

The doctor points out that the first thing I tell my patients is that, in regards to weight loss, diet and exercise alone will not be sufficient in the majority of cases. It is one of the reasons that many people suffer from the dreaded rebound effect after submitting to a diet, recovering all the lost weight.

Dr. Fradin-Read stresses the importance of the study to each patient from a global point of view, not only thinking about slimming

However, in addition to focusing on weight loss you have to do it in the persons life in general: Many patients who come to us tried to lose weight previously, but did not succeed and it was recovered, and even more. For successful weight loss and sustainable, we must look at the person in whole and not only addressing the weight separately.

Thats why, subject each patient to a detailed study: We analyzed the metabolic function: how the patient is beginning to develop insulin resistance? We observed the hormone, such an important part of the weight gain in the menopause. We investigated the levels of thyroid and cortisol. We have in mind the habits: why do most of us behave well all day and we crashed for the night? We evaluate the stress and sleep. We talk about mood and mental health. When addressing all of these elements, then we can start a custom diet and to recommend the exercise as needed, Then work.

Fradin-Read does not want to talk explicitly about Adele, because he has moral and legal obligations to protect the privacy of all patients, both mine as others. For that reason, I can not confirm nor deny any informationbut yes, I like to talk about my work as a health and various treatments, therapies, products and services offered by my practice, but do not provide information about specific individuals.

Dr. Fradin-Read is licensed in preventive medicine and anti-aging, in addition to possessing a university degree in nutrition. Part of its success lies in the fact that, when he starts working with a patient, what makes it so intensive: I Combine all the tools and methods in our therapeutic arsenal, starting with approaches that are more natural and changes in lifestyle, vitamins / supplements, to recommend peptides, rebalance hormones, and finally prescribe medications that are appropriate for each patient.

EC

A handful of nuts each day is indicated in any weight loss plan for its magnificent nutritional qualities

One of the tips that you share with all your customers is embrace the mediterranean diet, as well as the healthy menus suggested by the chef, Michel Gurard: the objective is to create balanced meals and customized for each client. The doctor develops a method for visual to make all of you to imagine a plate divided into several parts: green vegetables should occupy approximately two-thirds of the plate; protein-good source of one-third and the last part is reserved to the carbs. And, in addition, you can add healthy fats, such as olive oil, avocado or nuts.

Fradin-Read also emphasizes that the notion of the pleasure of eating is at the base of a successful diet in the long term. For this reason, it is important to create a personalized diet for each person and that is not always the sameWe are all different when it comes to our weight and, therefore, the same diet that works for one person might not work at another; it may even be that not even serve for the same person during all his life.

First recommend structural changes in the style of life, rebalancing the hormones and finally, prescribe appropriate drugs

A good diet to lose weight, according to dr. Fradin-Read, would be comprised of foods that are rich in nutrients, protein, good carbs, healthy fats and dairy. You can even add a glass of wine any day of the week. The goal is that people find good about yourself and maintain that commitment throughout his life.

Thats why, along with their processes of thinning, the american medical also offers a program anti-aging and skin rejuvenation. It does this by means of a test to assess the DNA of each person that enables you to identify the strengths and weaknesses that the body will have in the future. A formula called TruAge that aims to find biomarkers that will allow you to detect in advance various conditions such as cardiovascular disease, Alzheimers disease, cancer and others.

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The medical Adele reveals the secret to his weight loss and it is not the exercise - Play Crazy Game

Every week there are numerous scientific studies published. Heres a look at some of the more interesting ones.

More Worries About Emerging Viral Diseases

If the current COVID-19 pandemic is teaching the world anything, its that viral diseases can be extremely dangerous and disruptive. Researchers with the University of Colorado Anschutz Medical Campus released a new study calling attention to the emergence of mosquito-borne viral outbreaks in West Africa, including dengue (DNV), chikungunya (CHIKV) and Zika (ZIKV) viruses. They published their research in Acta Tropica.

The study reviewed 50 years of literature on arboviruses in West Africa. The goal was to define evidence of DENV, ZIKV and CHIKV and the distribution of their Aedes mosquito vectors in the region. They found strong evidence that transmission of these diseases is occurring in urban areas of West Africa, which is distinct from the rural transmission of yellow fever virus that has been historically present in the region. They found evidence that the epidemiology of arboviral disease in West Africa has shifted and that rapid urbanization and climate change could increase risk of outbreaks in the future.

Large arboviral outbreaks will occur around the world, said Elizabeth Carlton, assistant professor of environmental and occupational health at the Colorado School of Public Health and co-author of the study. Building awareness and surveillance capacity before the outbreaks occur can help detect outbreaks early and enable prompt and effective response to reduce health impacts.

Research lead Andrea Buchwald, a postdoctoral fellow, said, Emerging viruses are at the forefront of everyones attention due to the COVID-19 pandemic. It has underscored the importance of preparing for and preventing large viral outbreaks that can have massive public health and economic consequences. We hope our research will prompt the development of early warning systems and adoption of control measures to prevent infectious outbreaks in West Africa. This will greatly impact the spread and severity of future outbreaks.

Vaccine Design Leveraging Artificial Proteins

Investigators at Ecole Polytechnique Federale de Lausanne in France developed a computational approach to create artificial proteins, which they believe could be used to create safer and more effective vaccines. They note that when vaccines dont work, theres a tendency to think its because the antibodies produced arent protective, but usually its because the immune system is making the wrong type of antibodies. The new method was able to design artificial proteins that could precisely instruct the bodys immune system which antibodies to produce.

New Genetic Link for NASH Identified

Non-alcoholic steatohepatitis is a fatty liver disease similar to cirrhosis of the liver but in people who drink little or no alcohol. Researchers at German Diabetes Center, German Institute of Human Nutrition Potsdam-Rehbrucke (DlfE), and Helmholtz Zentrum Munchen, discovered new genes that play a role in fatty liver disease. The genes are IRGM, Ifgga2 and Ifgga4. They are responsible for the production of regulatory proteins of the family of immunity-related GTPases that counteract fat accumulation in the liver. A genetic variation causes formation of fewer of these proteins.

University of Waterloo researchers studying the 3D structure of the COVID-19 protein believe a specific class of diabetes drugs could potentially be used to treat COVID-19. The study has not yet been peer-reviewed, but they found evidence that dipeptidyl peptidase 4 inhibitors (DPP4 inhibitors) could bind to the protein. They are continuing research and hope to scale up to clinical trials. Common DPP4 inhibitors include AstraZenecas Onglyza (saxagliptin), Mercks Januvia (sitagliptin), Takedas Nesina (alogliptin) and Boehringer Ingelheims Tradjenta (linagliptin).

How Triglyceride is Made

Triglycerides are a type of dietary fat that are associated with increased risk of heart disease, diabetes, obesity and fatty liver disease. Researchers at Baylor College of Medicine identified a 3D structure and mode of action of an enzyme, acylglycerol O-acyltransferase-1 (DGAT1) that synthesizes triglycerides. It is also required for human dietary fat absorption and storage. DGAT1 is a known target for treating diabetes and metabolic diseases, so understanding the mechanism of action may lead to better interventions. The research was published in the journal Nature.

DGAT1 is a particularly interesting enzyme because it synthesizes triglycerides, which are the main component of hard fat, the type of fat usually found in the belly or midsection in our body, said co-corresponding author Ming Zhou, Ruth McLean Bowman Bowers Professor in Biochemistry in the Department of Biochemistry and Molecular Biology at Baylor. Triglycerides also are part of the particles that transport cholesterol high-density lipoproteins (HDL, or good cholesterol), and low-density and very-low-density lipoproteins (LDL and VLDLD, or bad cholesterols). Learning to regulate this enzyme can help regulate fat synthesis and potentially manage related conditions.

Accumulated Neuron Damage as We Age

Researchers at Massachusetts Institute of Technology (MIT) identified an enzyme called HDAC1 that is critical for repairing age-related DNA damage in genes associated with memory and cognition. In Alzheimers patients, as well as in normally aging adults, HDAC1 is often found in lower amounts. Their research suggests that restoring the enzyme could have benefits for both groups. The research was published in the journal Nature Communications.

It seems that HDAX1 is really an anti-aging molecule, said Li-Huei Tsai, director of MITs Picower Institute for Learning and Memory, and senior author of the research. I think this is a very broadly applicable basic biology finding, because nearly all of the human neurodegenerative diseases only happen during aging. I would speculate that activating HDAC1 is beneficial in many conditions.

In 2013, the same group published two papers linking HDAC1 to DNA repair in brain cells. The new research studied what happens when HDAC1-mediated repair didnt happen. They worked with mice engineered to not produce HDAC1 in neurons and another type of brain cell, astrocytes. At first there was no noticeable difference in DNA damage levels or behavior, but as the mice aged, DNA damage began to accumulate in the HDAC1-deficient mice and lost some of their brain plasticity and problems in memory and spatial navigation. The loss of HDAC1 was associated with a specific type of DNA damage called 8-oxo-guanine lesions.

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Research Roundup: Emerging Viral Diseases and More - BioSpace

BOSTONThe lockdown during the COVID-19 pandemic can be stressful for many, and yesstress can affect your immune system and overall health. Its impact on skin, aging and even hair loss can be severe.

During the Covid Dairies series, Chai With Manju spoke with three physicians who are at the top of their game about the trio of issues: skin care, hair restoration and anti-aging.

To view the full interview, please click here or on the video image below.

The three experts say that skin care and anti-aging secrets can make you look 10 years younger on and off camera during these days of virtual meetings. They also give some advice for men, including treatment for hair loss.

Interview also features the precautions being taken by Med Spa owners and hospitals to protect patients from COVID-19 during Phase-1 opening announced by Massachusetts Governor Charlie Baker on Monday.

Chai With Manju Spoke with the following physicians: Dr. Sonal Pandya, Dr. Rosy Sandhu and Dr. Shanthala Shivananjappa.

Dr. Pandya is a board-certified plastic surgeon who has been in practice at Lahey Clinic for almost 20 years. Her areas of interest include Surgical and NonSurgical Rejuvenation of the Face and Body.

She co-directs the Lahey Center for Cosmetic and Laser Surgery in Lexington, MA, a state-of-the-art laser center. Her surgical background and aesthetic training help provide individuals an unique combination treatments for each patient.

Dr. Sandhu is the founding director of Neem Medical Spa in Somerville, Lynnfield, and Winchester in Massachusetts. She is a board-certified internal medicine physician with ten years of hospital medicine experience. Dr. Sandhu is a member of the American Academy of Anti-Aging Medicine and the American Society of Bariatric Physicians. She is certified in aesthetics and medical weight loss by the International Association for Physicians in Aesthetic Medicine.

Dr. Sandhu has a special interest in anti-aging and aesthetic medicine, and has had years of training in advanced cosmetic procedures and medical weight loss. Her three centers offer a vast array of anti-aging, rejuvenating, weight loss, and wellness services. Given her Eastern roots and interest in Ayurveda, an ancient Eastern holistic science, Dr. Sandhu brings Neem-based natural wellness treatments to her practice. She has incorporated medical philosophies in many of the skin care treatments offered at Neem Medical Spa.

Dr. Shivananjappa is a board-certified, Harvard-trained anesthesiologist, who is the owner and medical director of ShanthalaMD MedSpa and Laser Center located in Peabody, MA.

Her expertise in the art of injectables, minimal invasive body contouring, skin tightening, platelet-rich plasma (PRP) treatments has earned her a reputation as one of the leading cosmetic physicians in the Northshore Area of Boston and RealSelf Top Doctor.

Prior to opening her medical spa, Dr. Shanthala was formerly an assistant professor at Yale University and a staff member at Massachusetts General Hospital. Her extensive experience working with plastic surgical patients in the operating room paired with years of training in nonsurgical cosmetic procedures has positioned her to have a deep understanding of and unique perspective on anti-aging treatments.

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Skin Care, Hair Restoration and Anti-Aging Tips From Dr. Pandya, Dr. Sandhu and Dr. Shivanjappa on Chai With Manju's Covid Diaries - India New England