Julia Alterman, PhD
Assistant Professor University of Massachusetts Chan Medical School
Small interfering RNAs (siRNAs) are a new class of oligonucleotide therapeutics that degrade disease-causing mRNA. However, restrictions imposed by the blood-brain barrier and short circulation times limit the therapeutic potential of siRNAs for brain disorders. In this webinar, Julia Alterman will discuss an innovative approach to achieve potent and long-term siRNA activity in the brain using a novel chemical scaffold that enables widespread siRNA brain delivery and gene silencing.
Topics to be covered
Wednesday, October 11th, 2023 | 2:00 PM - 3:00 PM Eastern Time This webinar will be available to view live and on demand.
Speaker
Julia Alterman, PhD
Assistant Professor University of Massachusetts Chan Medical School
RNA editing catalyzed by adenosine deaminases acting on RNA (ADARs) occurs naturally at thousands of sites across the human transcriptome. This process profoundly affects gene expression and influences a wide range of human diseases from cancer to neurological disorders. In this webinar, Michael Breen will discuss the role of ADAR-mediated RNA editing in neurodevelopmental disorders and how his team develops site-directed RNA editing therapeutics.
Topics to be covered
Wednesday, April 5th, 2023 | 2:30 PM - 3:30 PM Eastern Time This webinar will be available to view live and on demand.
Speaker
Michael Breen, PhD
Assistant Professor Icahn School of Medicine at Mount Sinai
RNA editing catalyzed by adenosine deaminases acting on RNA (ADARs) occurs naturally at thousands of sites across the human transcriptome. This process profoundly affects gene expression and influences a wide range of human diseases from cancer to neurological disorders. In this webinar, Michael Breen will discuss the role of ADAR-mediated RNA editing in neurodevelopmental disorders and how his team develops site-directed RNA editing therapeutics.
Topics to be covered
Wednesday, April 5th, 2023 | 2:30 PM - 3:30 PM Eastern Time This webinar will be available to view live and on demand.
Speaker
Michael Breen, PhD
Assistant Professor Icahn School of Medicine at Mount Sinai
More here:
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Recommendation and review posted by G. Smith
