if you can Find peoples genes explanation as to how serious the corona virus infection from different people coming from? This is not yet known. Scientists, however, believe that genetic factors may affect disease individual progression.
in Statistical genetics and epidemiology researcher Andrea Ganna the Finnish institute for molecular medicine FIMMist and his colleagues started the international cooperation process (switch to another service), where they are looking for corona virus patients DNA samples, connections to the predisposition to and severity of disease.
the vast Majority of people symptoms of the disease are very mild, and only some virus received with severe case of pneumonia.
our Hypothesis is that individuals genetics can explain the variation of the corona in the symptoms. We want to find the patients DNA mutations that could explain it, how serious the disease becomes, Ganna said.
the Purpose is to compare severe symptoms, but received no risk categories of patients DNA in patients with only minor or no symptoms.
Variations in ACE2 receptor, which is a corona virus used by invading cells within, can make the virus to travel from cell to either the hard or easily, said the Science magazine (you move to another service) immunologist Philip Murphy , whose laboratory discovered a fairly common mutation in another human cell membrane protein, which makes other people very resistant to HIVille.
possible to find a remedy for the corona virus treatment
the Project benefits would show up as in drug development than treatment of patients in the organisation.
we Know that certain drugs target specific genes. If these genetic mutations are also associated with COVIDIEN-19-severity of disease, it is possible that this drug could quite easily and quickly also use a corona virus infection.
If again manifested, that some people have a low genetic risk of getting severe symptoms, this information can be Gannan, according to the use of the treatment prioritization.
Data collected from around the world
Ganna and his colleagues has asked biobanks, hospitals and research institutions around the world to submit data to the corona virus patients DNA samples. Interested institutions can register according to the initiatives website (go to another service).
Gannan group does not handle DNA samples, but samples senders pretreatment genetic information, where you can find information about data science methods.
fimm is the director of Mark Daly is, in turn, promised that the FIMM makes DNA genotyping and analysis, if any institution does not have the resources to do it yourself. Gannan group edit the DNA data into a single format and publish them to the scientific community available.
in March, started the initiative has already collected a dozen partners, mostly in Europe and the united states. Also included is the Finngas (you move to another service), which has dna samples and health data for five percent of the Finnish population.
the Significant cooperation of the Italian Siena with the university. In siena, scientists collect samples of the 11 hospital in the North of Italy. The first samples came fimm was months.
Research is northern Italian to Gannan, but also personal meaning.
Im originally from Lombardia, where the corona virus infection have been highest in Italy. I know people who are seriously ill, so yes this is also a personal component, he said.
Also institute for Health and welfare THL to start their own national investigation of serious corona of symptoms predisposing factors. Research participate in an independent study also this international cooperation project.
the topic of the news also of the American Association for the Advancement of Science, published by science magazine Science Magazine (you move to another service).
see also :
Finnish drug hope to prevent the corona of deaths significantly First, however, it should also pass the United states medical authorities of the tests
the Problem overdrive the immune system this corona virus strikes the diseased
the Latest information about the corona virus in Finland and from the world
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The research team's hypothesis: Genes may determine how badly affected the corona to - Wire News Fax
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