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RPI researcher uses simple formula for chemical reactions to predict COVID-19 trajectory – Times Union

Posted: October 25, 2020 at 11:55 am

TROY A scientist at Rensselaer Polytechnic Institute has created a coronavirus transmission model inspired by one he uses to predict chemical reactions to help the Centers for Disease Control and Prevention forecast COVID-19 deaths across the country.

Developed by Yunfeng Shi, an associate professor of materials science and engineering at Rensselaer, and Jeff Ban, a professor of civil engineering at the University of Washington, the model uses fatality data collected by Johns Hopkins University and mobility data collected by Google to predict disease spread based on how much a population is moving within its community.

The researchers tested their model against data from 20 of the hardest hit counties in the United States and found it to be valid. Their findings are available in preprint on medRxiv, an online repository of papers that have been screened but not peer-reviewed.

The team has also been able to show how the forecasts change as schools open, communities lockdownand masks are mandated. The researchers website, which illustrates those forecasts, was developed by Tanooj Shah, a graduate student in Shis group.

Theres no mystery as to why theres an outbreak, Shi said. Theres no mystery to how we control it. The science is absolutely there. We want to use the model to give the local government some concrete predictive insight to implement certain policies.

Shi is a computational materials scientist who was curious about how simple chemical reaction analogs could be applied to forecasting COVID-19 transmission. Combined with Bans expertise in transportation and mobility, the two have developed a straightforward model that has been accurately predicting disease transmission.

They are now sharing their unique approach to forecasting COVID-19 spread with the CDC on a weekly basis, along with a collective of other research teams made up of infectious disease specialists, machine learning experts and modelers from across the nation. Combined, the models form an ensemble forecast from a multitude of perspectives.

The novelty of the model lies in the integration of physical modeling and data-driven approaches, which can bring useful insights about the infection and outbreak of COVID-19, Ban said. The findings of the research, such as the critical relative mobility indicator, can be used by policymakers for making informed decisions about when and how to reopen local economies.

The engineers plan to continue sharing their model results each week for the duration of the pandemic.

Pawel Keblinksi, the head of the Department of Materials Science and Engineering at Rensselaer, said the model is unique because of its simplicity and that it demonstrates that social mobility is a major contributing factor in controlling the spread of the virus.

"This is an example of the minimalist approach that Professor Shi used successfully to model complex physical reactive processes, including polymer or complex crystal growth," Keblinski said.

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RPI researcher uses simple formula for chemical reactions to predict COVID-19 trajectory - Times Union

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