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Garlic Good For Stomach and Colon Cancers

Posted: April 21, 2010 at 8:15 am

Meta-analysis supports protective effects of garlic against stomach and colon cancers

A meta-analysis of 18 studies reporting a relative risk estimate for consumption of garlic (Allium sativum) and cancer risk concluded that high consumption of raw or cooked garlic may be associated with protective effects against stomach and colorectal cancers. In the studies analyzed, the lowest consumption of garlic ranged from none to 3.5 g/week, while the highest consumption category ranged from any consumption to more than 28.8 g/week. The average difference between the highest and lowest consumption categories was 16 g/week. However,the researchers cautioned that publication bias (a tendency among researchers to publish only positive results) and other confounding factors may have influenced the positive results of their meta-analysis. Read more...

Ayurtox for Body Detoxification

Recommendation and review posted by G. Smith

ONS Books Wiki

Posted: April 20, 2010 at 11:44 pm

I recently reported on our use of Nature Precedings to archive different editions of the ONS Solubility Challenge book. One of the advantages is that Precedings automatically alerts visitors if more recent editions exist.

However, today I learned that there is a glitch to this system: it is not possible to link individual versions on Precedings to a corresponding book edition on LuLu. That means that if you find yourself on the Nature Precedings entry and want to order the book from LuLu it isn't obvious at all how to do so.

To resolve this issue once and for all I just created a wiki page (ONSbooks.wikispaces.com) to track every edition of the book. This is actually better because I can also provide links to all the available data archives and blog posts corresponding to each edition.

This is also the page where we will keep track of every edition of other Open Notebook Science books. The next one to be published shortly is for the UsefulChem project.

Recommendation and review posted by G. Smith

Another View of What to Do About Aging

Posted: April 20, 2010 at 8:16 am

An interesting paper: "The idea that bodies wear out with age is so ancient, so pervasive, and so deeply rooted that it affects our thought in unconscious ways. Undeniably, many aspects of aging, e.g., oxidative damage, somatic mutations, and protein cross-linkage are characterized by increased entropy in biomolecules. However, it has been a scientific consensus for more than a century that there is no physical necessity for such damage. Living systems are defined by their capacity to gather order from their environment, concentrate it, and shed entropy with their waste. Organisms in their growth phase become stronger and more robust; no physical law prohibits this progress from continuing indefinitely. Indeed, some animals and many plants are known to grow indefinitely larger and more fertile through their lives. The same conclusion is underscored by experimental findings that various insults and challenges that directly damage the body or increase the rate of wear and tear have the paradoxical effect of extending life span. Hyperactive mice live longer than controls, and worms with their antioxidant systems impaired live longer than wild type. A fundamental understanding of aging must proceed not from physics but from an evolutionary perspective: The body is being permitted to decay because systems of repair and regeneration that are perfectly adequate to build and rebuild a body of ever-increasing resilience are being held back. Regardless of the reason for this retreat, it should be more fruitful to focus on signaling to effect the ongoing activity of systems of repair and regeneration than to attempt repair of the manifold damage left in the wake of their failure."

View the Article Under Discussion: http://dx.doi.org/10.1089/rej.2009.0967

Read More Longevity Meme Commentary: http://www.longevitymeme.org/news/

Recommendation and review posted by Fredricko

Steps Towards Controlling Regeneration

Posted: April 20, 2010 at 8:16 am

Spurring regeneration by use of signalling molecules is a promising field of medical development. Here is an example from the Technology Review: "scientists have identified a pair of peptides that can stimulate new cell growth and improve heart function in rodents induced to have heart attacks. [Researchers are] now testing one of the peptides, periostin, in pigs induced to have heart attacks. Because these animals have hearts similar in size to humans, they provide a good model for testing new therapies prior to human clinical trials. Preliminary results show that injecting the peptide into the pericardium, the lining around the heart, seems to help. ... [This] approach is, to some degree, in competition with stem-cell therapy, which is already being tested in humans. Scientists are working on different ways of harvesting and delivering stem cells to patients with heart disease, and clinical trials have so far yielded mixed results. Transplanted cells appear to have difficulty surviving and integrating into their new environment. In fact, some scientists suggests that benefit of cell transplants comes from the cells ability to stimulate innate growth. Triggering this process with peptides [may] be a simpler method of treatment of certain conditions such as cardiomyopathy [an enlarged heart] where the problem is lack of viable, contractile heart muscle cells."

View the Article Under Discussion: http://www.technologyreview.com/printer_friendly_article.aspx?id=25139

Read More Longevity Meme Commentary: http://www.longevitymeme.org/news/

Recommendation and review posted by Fredricko

Rare flowers and common herbal supplements get unmasked with plant DNA barcoding

Posted: April 20, 2010 at 8:16 am

NEW YORK--Will exotic orchids soon be subjected to the same genetic scrutiny as some luxury caviars? That is just one of the coding conundrums that scientists convened at the New York Botanical Garden in the Bronx to discuss on a cloudy mid-April afternoon. [More]

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Recommendation and review posted by Fredricko

Marylin Monroe Exposed

Posted: April 20, 2010 at 8:14 am

Marylin Monroe chest x-ray

This apparent xray of Marylin Monroe’s chest, taken in 1952 at a Florida hospital when she was treated for endometriosis, is set to sell at a Hollywood auction this summer.  While some people may think this is another ridiculous celebrity auction piece and may wonder who in the world would want an xray of Marylin Monroe’s chest, I actually think it’s quite interesting.  Even the xray exemplifies that classic Marylin Monroe contour!

[spotted by Benoit via news:lite]

Recommendation and review posted by G. Smith


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