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Clinical Neurology: Harmeet Singh, MD: Leesburg, VA

Posted: November 17, 2018 at 9:42 pm

Harmeet Singh, MD is a neurology specialist with over 20 years of professional experience. Dedicated to helping his patients regain control of their lives, Dr. Singh provides the latest in neurological treatment options along with compassionate, patient-centered care at Clinical Neurology, in Leesburg, Virginia.

After completing medical school at Dayanand Medical College & Hospital, Ludhiana in India, Dr. Singh went on to complete his residency and fellowship at Temple University Hospital in Philadelphia.

As a neurology specialist, Dr. Singh understands the exhausting nature of living with chronic conditions and he works hard to offer an array of cutting-edge and alternative treatment options to let his patients have a direct role in how they receive comfort and care. Whether it's acupuncture, Botox, or more classic treatment options for neurological conditions, Dr. Singh knows that each treatment option has its place.

Combining experience in a wide variety of treatment and testing options with friendly, knowledgeable staff and a focus on personalized patient care, Dr. Singh is the leading neurology outpatient doctor in northern Virginia. Clinical Neurology is currently accepting new patients from Leesburg, Lansdowne, Ashburn, Purcellville, Sterling, Herndon and surrounding areas.

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Clinical Neurology: Harmeet Singh, MD: Leesburg, VA

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Alex Chiu Immortality Magnetic Rings – amazon.com

Posted: November 17, 2018 at 1:43 am

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ALEX CHUI'S AUTHENTIC IMMORTALITY (WHITE)RINGS (up to 4000 GAUSS TOTAL FOR BOTH RINGS- up to 1000 GAUSS PER MAGNET WITH 2 MAGNETS PER RING) WHITE RINGS US PATENT Number 5,989,178 WE BUY IN LARGE QUANTITIES DIRECTLY FROM ALEX CHIU TO SAVE YOU. WE ARE AN AUTHORIZED DISTRIBUTOR OF HIS PRODUCTS. THESE RINGS ARE THE REAL DEAL . According to Alex Chui based on testimonies,facts, and proofs people are believed to be able to stay physically young forever by using his new inventions The Eternal Life Rings. The Eternal Life Rings are to be worn on both small fingers of a user during sleep. They consist of ceramic magnets and plastic braces which hold magnets onto the fingers of the user. When placing the magnetic devices, the magnetic pole on the right side of the human body is opposite to the left side. With a opposite pole on each side of the human body, blood circulation and electric current of the body are enhanced. The enhanced blood circulation and electric current increase METABOLISM in order to fight the aging process. INSTRUCTIONS ARE INCLUDED WITH SHIPMENT.

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Alex Chiu Immortality Magnetic Rings - amazon.com

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All Things Stem Cell Bioengineering Organs and Tissues …

Posted: November 17, 2018 at 1:42 am

While there is great potential for using stem cells in regenerative therapies, there is still a ways to go before it can be considered a proven practice, although recent breakthroughs, and one specific trial in particular, makes it seem much closer. Recently, the first human tissue-engineered organ using stem cells was created and transplanted successfully into a patient. Other tissue regeneration efforts with stem cells have also recently made many breakthroughs, emphasizing the potential of using stem cells in future tissue transplants.

In the first reported instance of using stem cells to bioengineer a functional human organ, Paolo Macchiarini and his research group used a patients own stem cells to generate an airway, specifically a bronchus, and successfully grafted it into the patient to replace her damaged bronchus (See Figure 1). Macchiarinis group bypassed the problem of immune rejection by using the patients own stem cells. Additionally, by combining a variety of bioengineering efforts, no synthetic parts were involved in the creation of the organ; it was made entirely of cadaveric and patient-derived tissues (Macchiarini et al., 2008; Hollander et al., 2009).

Figure 1. In order to create a patient-compatible replacement bronchus, Macchiarinis group removed and decellularized a trachea from a cadaveric donor, grew cells removed from the patient on the trachea in a bioreactor, and then transplanted the bioengineered airway into the patient, successfully replacing their defective bronchus (Macchiarini et al., 2008).

The relatively unique and tragic situation of the patient led Macchiarinis group to test this novel organ transplant on her, which had previously been tried in mouse and pig models. Due to a severe tuberculosis infection, the 30-year-old female patients left bronchus had become near-collapse; breathing was so impaired that the patient could no longer carry out simple domestic chores. After several other approaches did not succeed in fixing the bronchus, it was decided that the best option was to remove and replace the bronchus. Normally replacement of large airway pieces and other organs is a significant problem because the patient must be on immunosuppressant medications for life to prevent rejection of the new tissue, and this can shorten the patients lifespan by 10 years on average; using the patients own stem cells got around rejection (Macchiarini et al., 2008; Hollander et al., 2009).

To create the replacement bronchus, a cadaveric donor airway was obtained and decellularized, or treated so that all donor cells would be removed. A segment of trachea was removed from a cadaveric donor and all connected tissues carefully detached. To prevent immune rejection by the patient, which can be caused by the presence of foreign cells and different major histocompatibility complexes (MHC), all cells and parts of cells had to be removed from the donor trachea. To ensure complete removal of all donor cellular components, the trachea underwent an extensive, previously established decellularization procedure over a period of 6 weeks, which involved the trachea being incubated with detergents and deoxyribonucleases (enzymes that degrade DNA) for 25 cycles (Macchiarini et al., 2008; Conconi et al., 2005). The researchers confirmed that donor cells, including MHC-positive cells, were absent, leaving only the cartilage of the trachea intact (Macchiarini et al., 2008).

The decellularized trachea acted as a scaffold for the patients cells to be grown on; the stripped airway was incubated in a novel bioreactor with two different kinds of cells from the patient. Epithelial cells were removed from the mucosa, or moist tissue lining, of the patients right bronchus. These cells were taken and cultured, or grown, inside the donor trachea. The second type of cell used was chondrocytes. To create chondrocytes the researchers removed bone marrow from the patient and isolated out a population of mesenchymal stem cells (MSCs). The MSCs were induced to differentiate into, or become, chondrocytes using a standard protocol (i.e. specific factors were added to the growth media) for three days. These chondrocytes were seeded on the outside of the trachea. The cells were grown in different media used inside and outside of the bioreactor, media specific to the epithelial cells or chondrocytes. The cells were cultured on the trachea in the bioreactor for four days, at which point the researchers had bioengineered a human airway lacking any synthetic parts (Macchiarini et al., 2008).

The portion of the patients left bronchus that was near-collapse was removed and successfully replaced by the bioengineered trachea, now acting as a segment of bronchus. After a month in the patient, the transplanted trachea was indistinguishable from a normal bronchus, as compared to the patients unaffected right bronchus and the surrounding bronchus tissue. The transplanted airway quickly also displayed completely normal function (Macchiarini et al., 2008). One year later, the graft and patient are still doing fine (Asnaghi et al., 2009).

While the case of this successfully bioengineered and transplanted organ is a breakthrough, improvements are needed to make such transplants feasible. Because Macchiarinis group used a donor graft, the original cadaveric trachea segment, these transplants are limited by available donors. It is hoped that research efforts will lead to fully-tissue engineered organ transplants without the need of such donor grafts. If this is possible, the current shortage of donor tissue and organs can be dealt with and a large aging population can be much more effectively treated (Hollander et al., 2009).

Aside from Macchiarinis report, several other research groups have made breakthroughs in bioengineering organs and tissues recently. One group reported creating skeletal muscle segments using a synthetic scaffold to shape and grow cells on (Bian and Bursac, 2009). Specifically, these researchers used a silicon-based polymer (polydimethylsiloxane, or PDMS) to create micromolds with pegs, or elongated posts, sticking up from the molds. Muscle cells in a gel solution were poured onto the mold and polymerized together. This created a porous skeletal muscle network that was densely packed, with uniformly aligned muscle fibers that spontaneous contracted at the macroscopic level. In the future this approach could create customized, functional skeletal muscle tissue for reconstructing damaged muscle (Bian and Bursac, 2009). Similarly, another group discusses potential in using stem cells to rescue damaged heart muscles (Shimizu et al., 2009). Researchers are also investigating the feasibility of using epithelial stem cells in bioengineered intestines, based on polymer scaffold experiments performed in rats (Day, 2006). Intestinal transplantation, often needed for short bowel syndrome caused by a variety of reasons, is a significant problem because of the extremely active immune system of the intestines (Day, 2006). Other researchers are focusing on the great potential of mesenchymal stem cells (such as were used in Macchiarinis report) in general wound healing; these cells can differentiate into many different kinds of cells, be isolated in significant numbers, potentially migrate to areas they are needed in, and may be immunosuppressive (Fu and Li, 2009). The use of nanomaterials, which can mimic proteins on the surface of cells and tissues, also hold much potential for future scaffold designs in regenerative medicine (Zhang and Webster, 2008).

While Macchiarinis patient represents a significant breakthrough, it is still a single success that must be repeated to be proven. The transition to the clinic of other stem cell-based regenerative therapies will also require extremely careful characterization of each individual procedure. There are still many obstacles to overcome before such therapies can become common practice. Those interested in receiving stem cell therapies should be aware of the possible risks involved; the Department of Healths Gene Therapy Advisory Committee lists such potential hazards associated with undergoing stem cell therapies.

References

Asnaghi, M. A., Jungebluth, P., Raimondi, M. T., Dickinson, S. C., Rees, L. E. N., Go, T., Cogan, T. A., Dodson, A., Parnigotto, P. P., Hollander, A. P., Birchall, M. A., Conconi, M. T., Macchiarini, P., and Mantero, S. A double-chamber rotating bioreactor for the development of tissue-engineered hollow organs: From concept to clinical trials. Biomaterials. 2009. 30(29): 5260-5269.View Article

Bian, W. and Bursac, N. Engineered skeletal muscle tissue networks with controllable architecture. Biomaterials. 2009. 30(7): 1401-1412.View Article

Conconi , M. T., De Coppi, P., Di Liddo, R., Vigolo, S., Zanon, G. F., Parnigotto, P. P., and Nussdorfer, G. G. Tracheal matrices, obtained by a detergent-enzymatic method, support in vitro the adhesion of chondrocytes and tracheal epithelial cells. Transpl. Internat. 2005. 18(6): 727-734.View Article

Day, R. M. Epithelial stem cells and tissue engineered intestine. Curr. Stem Cell Res. Ther. 2006. 1(1): 113-120.View Article

Fu, X. and Li, H. Mesenchymal stem cells and skin wound repair and regeneration: possibilities and questions. Cell and Tiss. Res. 2009. 335(2): 317-321.View Article

Hollander, A., Macchiarini, P., Gordijn, B., and Birchall, M. The first stem cell-based tissue-engineered organ replacement: implications for regenerative medicine and society. Regen. Med. 2009. 4(2): 147-148.View Article

Macchiarini, P., Jungebluth, P., Go, T., Asnaghi, M. A., Rees, L. E., Cogan, T. A., Ddson, A., Martorell, J., Bellini, S., Parnigotto, P. P., Dickinson, S. C., Hollander, A. P., Mantero, S., Conconi, M. R., Birchall, M. A. Clinical transplantation of a tissue-engineered airway. The Lancent. 2008. 372(9655): 2023-2030.View Article

Shimizu,T., Sekine, H., Yamato, M., Okano, T. Cell Sheet-Based Myocardial Tissue Engineering: New Hope for Damaged Heart Rescue. Curr. Pharm. Design. 2009. 15(24): 2807-2814.View Article

Zhang, L., and Webster, T. J. Nanotechnology and nanomaterials: Promises for improved tissue regeneration. Nanotoday. 2009. 4(1): 66-80.View Article

Image of Macchiarinis Bioengineered Bronchus Replacement was modified from Wikipedia and redistributed freely as it is in the public domain.

adminBioengineering, Mesenchymal Stem Cellsadult, clinical trials, mesenchymal, regenerative medicine 2009-2010, Teisha Rowland. All rights reserved.

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All Things Stem Cell Bioengineering Organs and Tissues ...

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Inova Integrative and Functional Medicine – Inova

Posted: November 15, 2018 at 1:45 pm

If you are an existing patient, please download your patient records from thepatient portal prior to March 30, 2018. Download your patient record

Going forward, we will using MyChart: Personal and Secure Health Record.Learn more about MyChart

Inova Integrative and Functional Medicine emphasizes nutrition, exercise and lifestyle adjustments for optimum health. We use approaches that are backed by proven research and studies. Learn about our services

Our physicians listen closely to patients during new visits that typically last an hour, asking questions about all aspects of their lifestyle to create a complete picture. Our integrative approach combines conventional and complementary therapies to facilitate healing for acute and chronic conditions. Meet our physicians

Functional Medicine addresses the underlying causes of disease, using a systems-oriented approach and engaging both patient and practitioner in a therapeutic partnership. It is an evolution in the practice of medicine that better addresses the healthcare needs of the 21st century. By shifting the traditional disease-centered focus of medical practice to a more patient-centered approach, Functional Medicine addresses the whole person, not just an isolated set of symptoms. Functional Medicine practitioners spend time with their patients, listening to their histories and looking at the interactions among genetic, environmental, and lifestyle factors that can influence long-term health and complex, chronic disease. In this way, Functional Medicine supports the unique expression of health and vitality for each individual. Learn more about Functional Medicine

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Inova Integrative and Functional Medicine - Inova

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About Us – Texas Integrative Medicine

Posted: November 15, 2018 at 1:45 pm

Jennifer started her career in Finance because thats what everyone in the NY metropolitan did after college. She could never ignore this urge to follow her passion for health and fitness though, so after having her first child she decided to pursue her personal training certification with the NSCA. Jennifer loved working with clients on their health and fitness, but she soon realized that she was only addressing a small portion of their overall well-being by focusing on fitness. She realized she needed to address the whole body, including nutrition, sleep, and mindset, all the things that come along with being a holistic practitioner. Plus, she was struggling herself with energy and thyroid issues.

So, after years of trying to do it all and be it all, the perfect mother, the perfect wife, the perfect trainer in the perfect shape, eating the so-called perfect diet, Jennifer happened upon a holistic nutrition and health course that called out her name! Functional Diagnostic Nutrition (FDN). FDN is about getting to the root cause of your health issues, not the simple band-aid approach of covering up symptoms that reappear later in different and sometimes worse ways. Once the root is addressed, the body can heal itself.

Her FDN coursework helped Jennifer heal herself from her own adrenal and thyroid issues. How? Through lab testing of markers of well-being such as hormones and digestion, interpreting those results, and implementing a protocol of DRESS: Diet, Rest, Exercise, Stress reduction, and Supplementation. Jennifer now has the privilege of doing this with her clients. Shes been there, and she can help you!

In addition to her nutrition and fitness background, Jennifer is trained as a NLP Master Practitioner. NLP stands for Neuro-Linguistic Programming. Neuro refers to your neurology, linguistic refers to language, and programming refers to how that neural language functions. In other words, NLP is the process of learning the language of ones own mind, so you can take more control of your outcomes (what you are getting in life). By using the practice of NLP with clients, Jennifer can help clients achieve their goals by utilizing more productive self-talk (instead of unproductive negative self-talk that so many of us dont even realize is likely sabotaging our goals). Language is a powerful tool that can be utilized in achieving health goals.

Jennifer has lived all over the world, from San Francisco to Sydney and Singapore, and is enamored with travel. She loves learning from other cultures, particularly when it comes to using food as medicine. Outside of work Jennifer enjoys spending time with her husband (another world traveler), and their three children.

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About Us - Texas Integrative Medicine

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Holistic and Integrative Medicine | Sutter Health

Posted: November 15, 2018 at 1:45 pm

When youre in the midst of a health crisis, you may feel scared, overwhelmed or in pain. You need more than tests, surgeries and medication; you need healing touch, a listening ear and inspiration to create a renewed sense of your own health. You may have a health condition that isn't easily diagnosed or treated with Western medicine alone, and want to add new tools to help you regain physical, mental, emotional and spiritual balance and resilience.

Our holistic and integrative medicine practitioners provide just that. Sutters Institute for Health & Healing, founded in 1994 and the first integrative medicine clinic certified by the State of California, is a nationally recognized pioneer in integrative health. At locations across Northern California, we provide evidence-based care that combines modern medical approaches with proven, personalized integrative medicine therapies. Whether you want physician oversight to manage a serious illness or are seeking acupuncture treatment or a therapeutic massage, our goal is to provide the partnership and resources you need to optimize your overall health and well-being.

Understanding Integrative Medicine

Integrative medicine expands the traditional focus on disease and symptoms to incorporate your full potential for wellness. It shifts the emphasis from establishing whats wrong to finding out how to live better through deep and enduring health practices.

Integrative medicine also expands the treatment landscape to include options that reflect amind-body-spirit perspective. For any given clinical concern or need, an integrative approach may incorporate ancient traditions such asChinese medicine and acupuncture as well as modern forms of restoring balance such as functional medicine,mindfulness training andnutrition.

You may come to us with a condition for which conventional medicine may not have all the answers. You may want to enhance the care you are already receiving. Or you may simply be interested in exploring different approaches to wellness and prevention. Whatever your state of health, we can guide you to holistic changes and support you as you put those into practice.

Our staff are all board-certified, Western-trained doctors and clinicians specially trained in integrative practices. Across our Northern California locations, we offer in-depth integrative medicine consultations, focused integrative medicine treatments such as acupuncture and chiropractic services. In San Francisco, we also offer integrative primary care services.

Conditions We Treat

We help children and adults with a variety of health conditions. We offer expertise in areas including:

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Holistic and Integrative Medicine | Sutter Health

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