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5 ways your cell phone can save your life

Posted: February 6, 2011 at 6:16 pm

From CNN:

You can use apps and other tools to turn your cell phone into a safety tool:

1. Program your cell phone so people can find you
2. Put your "in case of emergency" contact into your cell phone
3. Put your medical information on your cell phone
4. Get an app that teaches you first aid and CPR
5. Find help nearby

References:

Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.


Recommendation and review posted by G. Smith

Diagnosis, treatment, and prognosis of glioma: 5 new things

Posted: February 6, 2011 at 6:16 pm

5 new ideas that are changing the management of brain tumor patients:

1. Prognosis and glioma subtypes. The cell of origin of the glioblastoma has never been defined. In his pioneering work “Death Foretold,” Dr. Christakis says “prognosis gives diagnosis its affective component, striking fear in patients and physicians alike.” There has been a lot of therapeutic nihilism about the treatment of glioblastoma, but that is now changing. Image source: Sen. Ted Kennedy who died of glioma in 2009.

2. Diagnosis and imaging mimics. Acute stroke in the luxury perfusion stage is probably the most common mimic of a brain tumor. Diffusion MRI sequences and perfusion CT scan are helpful in differentiating stroke from tumor by showing hypoperfusion as would be expected, rather than hyperperfusion seen in tumors.
3. Treatment and pseudoprogression. Temozolomide is an oral drug, which is changed into MTIC (methyltriazeno-imidazole-carboxamide), a DNA-methylating drug. The concomitant use of radiation therapy and adjuvant temozolomide in glioblastoma patients showed a median survival of 14.6 months.
Increase in contrast enhancement and mass effect can mimic tumor progression. The term “pseudoprogression” describes the inflammatory reaction to effective treatment. Increasing steroid doses can control the edema.
4. Antiepileptic drugs. Prophylactic use of antiepileptic drugs (AEDs) is not recommended in patients with brain tumor due to lack of efficacy. The interactions between AEDs and chemotherapy can also be problematic.
5. Quality of life issues. The incidence of common symptoms reported was fatigue (90%–94%), sleep disturbance (32%–52%), headache (50%), and cognitive impairment (50%). Ritalin, modafinil, and Aricept have all been shown to have a positive effect on mood and cognition. Cause of death was presumed brain herniation 73% of the time.
References:
Diagnosis, treatment, and prognosis of glioma. Five new things. Lynne P. Taylor, MD. Neurology November 2, 2010 vol. 75 no. 18 Supplement 1 S28-S32.
Image source: Sen. Kennedy who died of glioma in 2009, Wikipedia, GNU Free Documentation license.

Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.


Recommendation and review posted by G. Smith

New schizophrenia drug lurasidone (Latuda) does not cause significant weight gain

Posted: February 6, 2011 at 6:16 pm

Lurasidone (Latuda) was approved for the treatment of schizophrenia in adults in October 2010. Lurasidone acts as a D2, 5-HT2A, 5-HT7, and ?2C-adrenergic receptor antagonist, and 5-HT1A receptor agonist.

Once-daily lurasidone did not cause significant weight gain, a common side effect of other schizophrenia drugs. Possible treatment side effects do include drowsiness, agitation, tremors, and nausea.

Lurasidone will carry a boxed warning - required of all atypical antipsychotics - about the increased risk for stroke and death when used off-label to treat dementia-related psychosis in older patients.

Other severe but rare side effects include neuroleptic malignant syndrome and tardive dyskinesia.

References:
New Schizophrenia Drug Approved. Journal Watch.

Image source: Lurasidone, Wikipedia, public domain.

Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.


Recommendation and review posted by G. Smith

Concussion Recovery – Mayo Clinic Video

Posted: February 6, 2011 at 6:16 pm

Mayo Clinic Video: The news has been filled with stories about the dangers of concussions in sports like high school football. Doctors at Mayo Clinic say that pulling kids off the field until they have completely recovered is key to keeping them healthy. But some players who've suffered concussions choose not to get back in the game. They don't want to risk possible consequences of repeat and serious head injury.

Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.


Recommendation and review posted by G. Smith

Laptop Computer-Induced Erythema ab Igne

Posted: February 6, 2011 at 6:16 pm

Erythema ab igne is a skin reaction caused by exposure to heat. It is also known as hot water bottle rash, fire stains, and toasted skin syndrome. Ignis is the latin word for "fire".

In this case report a 12-year-old boy presented with erythema ab igne on his left thigh caused by the use of a laptop computer. This is the youngest of the 10 reported patients with this laptop-induced dermatosis since its first description in 2004.

Erythema ab igne is a reticular, pigmented, sometimes telangiectatic dermatosis that is caused by prolonged exposure to a heat or infrared source (see pictures from different cases at DermNet).

In laptop-induced erythema ab igne, the localization on the thighs and asymmetry are characteristic. The heat originates from the optical drive, the battery, or the ventilation fan of the computer.

References:
Laptop Computer–Induced Erythema ab Igne in a Child and Review of the Literature. PEDIATRICS Vol. 126 No. 5 November 2010, pp. e1227-e1230 (doi:10.1542/peds.2010-1390)
Erythema Ab Igne. eMedicine Specialties > Dermatology > Environmental.
Image explanation:  I was not able to find online photos of erythema ab igne labeled for reuse, hence the image of a laptop from Amazon.com.

Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.


Recommendation and review posted by G. Smith

Exercise pioneer Jack LaLanne died at 96 and was doing great until the very end (video)

Posted: February 6, 2011 at 6:16 pm

Jack LaLanne, the fitness pioneer who inspired TV viewers to trim down, eat well and pump iron for decades (34 years), died at 96 of respiratory failure due to pneumonia at his home in California.

He ate healthy and exercised every day of his life up until the end. Just before he had heart valve surgery in 2009 at age 95, Jack Lalanne told his family that dying would wreck his image.

"The only way you can hurt the body is not use it," LaLanne said. "Inactivity is the killer and, remember, it's never too late."

His workout show was a television staple from the 1950s to the '70s. LaLanne and his dog Happy encouraged kids to wake their mothers and drag them in front of the television set. He developed exercises that used no special equipment, just a chair and a towel.

He said his own daily routine usually consisted of two hours of weightlifting and an hour in the swimming pool.

When he turned 43 in 1957, he performed more than 1,000 push-ups in 23 minutes on a TV show. At 60 he swam from Alcatraz Island to Fisherman’s Wharf handcuffed, shackled and towing a 1,000-pound boat. At 70, handcuffed and shackled again, he towed 70 boats, carrying a total of 70 people, a mile and a half through Long Beach Harbor.

He had a blog too: http://www.jacklalanne.com/blog

Jack LaLanne at Age 95 (CBS). He had just published his 11th book at the time.

Twitter comments:

@TracylynnHolt (Tracyfogelstrom-Holt) But lived an awesome LIFE...:):)

@DrVes: Sure. He was great. I wish everybody could make it to 96 in reasonable health... πŸ™‚

@Thinkbirth (Carolyn Hastie): I love the videos, thanks for sharing "Jumping Jack" πŸ™‚ so good to see that.

References:

Exercise pioneer Jack LaLanne dies at 96 at California home; inspired generations to get fit. Chicago Tribune.
Jack LaLanne, Fitness Guru, Dies at 96. TIME.
Jack LaLanne, Founder of Modern Fitness Movement, Dies at 96. NYTimes.

Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.


Recommendation and review posted by G. Smith


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