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Resveratrol Benefits, Side Effects and Food Sources – Dr. Axe

How do the French eat more fat, sugar and rich foods, plus drink more wine, but still have less heart health issues? The answer to this puzzling question, commonly known as the french paradox, is believed to be due to a higher intake of a specific phytonutrient called resveratrol, found naturally in superfoods like red wine. Like other antioxidants and phytonutrients, such as lycopene found in tomatoes or lutein found in carrots, resveratrol is a powerful compound that regenerates the body all the way at the cellular level.

Research published over the past several decades in many medical journals, including the European Journal of Food Pharmacology andAmerican Journal of Hypertension,found that resveratrol (in this case from red wine) decreases the risk of heart disease among other common health concerns.

Although he might not have known exactly how wine was able to promote better health, even Plato promoted the health perks of drinking it in moderation. Hes been quoted as saying, Nothing more excellent or valuable than wine was ever granted by the gods to man. (1)

In case youre wondering, you dont have to be a wine drinker to benefit from resveratrol. Other sources include deeply colored berries and real dark chocolate and cocoa. Along with helping to keep arteries clear from plaque buildup and protecting an aging heart, this phytonutrienthas many other health benefits too including reducing inflammation, potentially helping to prevent obesity and protecting cognitive health among the elderly.

Resveratrol is a polyphenic bioflavonoid antioxidant thats produced by certain plants and found in foods and drinks that are known to halt the effects of aging. Resveratrol is classified as aphytoestrogen because of its ability to interact with estrogen receptors in a positive way.

Plants that produce resveratrol and other types of antioxidants actually do so partly as a protective mechanism and response to stressors within their environments, including radiation, the presence of insects or other predators, injury, and fungal infections. Today, resveratrol is believed to be one of the most potent polyphenols and strongest protectors against symptoms associated with aging andfree radical damage.

Studies show that the most naturally abundant sources of resveratrol (not to mention many other protective phytonutrients, vitamins and minerals) are plants, including the skin of red grapes, red wine, raw cocoa, and dark berries, such as lingonberries, blueberries, mulberries and bilberries.

Red wine is probably the best known source, mostly due to its high levels thanks to the fermentation process that turns grape juice to alcohol. During production of red wine, grape seeds and skins ferment in the grapes juices, which have positive effects on levels and availability of resveratrol.

The benefits of resveratrol were first discovered when researchers found that yeast and other microbes, insects and animals fed resveratrol experienced an increased life span as a result. Various studies continued to confirm its amazing anti-aging benefits, demonstrated in studies conducted on fruit flies, fish, mice and nematode worms, all of which lived longer compared to control groups that were not treated with this phytonutrient.

Related: Fisetin: A Senolytic Antioxidant for Healthy Aging & More

Resveratrol is a powerful antioxidant that neutralizes free radicals produced during everyday bodily functions, such as eating and exercise. Free radical damage is accelerated due to poor lifestyle habits like smoking, eating an unhealthy diet, and in response to environmental pollution and toxicity.

If left unchecked, free radicals can damage cells and are thought to be a cause of life-threatening diseases andearlier death. Consuming plant foods high in antioxidants and phytonutrients has been shown to offer antioxidative, anticarcinogenic and antitumor benefits that protect adults from many age-related diseases. (2)

According to research published by the Department of Pharmacology at the University of Seville in Spain, One of the most striking biological activities of resveratrol soundly investigated during the late years has been its cancer-chemopreventive potential. In fact, recently it has been demonstrated that it blocks the multistep process of carcinogenesis at various stages: tumor initiation, promotion, and progression.

Its believed the mechanisms for its cancer-protecting activities involves downregulation of the inflammatory response through inhibition of synthesis and release of pro-inflammatory mediators, among other activities. (3)

Because of its anti-inflammatory activity, resveratrol has been shown to offer protection against atherosclerosis (thickening of the arteries that cuts off blood flow), high LDL bad cholesterol, formation of blood clots and myocardial infraction. Consuming more has also been shown to help improve circulation and have beneficial effects on glucose and lipid metabolism in some with higher risk for metabolic syndrome. (4)

Itadori tea, one significant source of resveratrol, has long been used in Asian countries, including Japan and China, as a traditional herbal remedy for preventing heart disease and strokes.

Resveratrol is particularly unique as its antioxidants can cross the blood-brain barrier to protect the brain and the nervous system, unlike other antioxidants. Recent studies done by researchers at the Nutrition Research Center at Northunbria University in the U.K. showed that resveratrol noticeably increased blood flow to the brain, suggesting a considerable benefit to healthy brain function and neuroprotective effects.

This means consuming more can increase protection against cognitive/mental problems, including Alzheimers, dementia and others. Other study findings, such as results published in the Journal of Agricultural Food Chemistry, demonstrated that even a single infusion of resveratrol could elicit neuroprotective effects on cerebral (brain) neuronal loss and damage. (5) This resulted from increased free radical scavenging and cerebral blood elevation due to resveratrols effects.

Findings from animal studies have found that resveratrol exerts beneficial effects on rodents fed a high-calorie diet, helping prevent fat storage and regulating insulin levels. (6) Others research has shown that resveratrol may help reduce body weight and adiposity in obese animals, which some experts believe is due to activating the SIRT1 gene thats believed to protect the body against the effects of obesity.

Its not totally clear how this translates to humans consuming foods or drinks like wine and berries, but studies have found links between adults eating balanced diets that include moderate amounts of wine and healthier body weights.

Animal studies involving diabetic rats have demonstrated that resveratrol may be able to reduce hyperglycemia and may also possibility be of use in preventing and/or treating both obesity and diabetes.

Resveratrol may be helpful for those with diabetes and prediabetes byreducing complications (like nerve damage and damage to the heart) and helping manage insulin levels. Its known that this phytoestrogenpositively affects insulin secretion and blood insulin concentrations, according to animal studies. (7)

As you can tell from all the benefits described above, resveratrol and sources that provide it, including red wine, are more than just powerful heart-protectors. Theyre also strong brain-boosters, among many other things. People use resveratrol for all sorts of anti-aging benefits, considering research suggests that itcan help:

Should You Take Resveratrol Supplements?

Because the FDA does not regulate supplements, many health authorities are not convinced that taking resveratrol supplements or extract will have much payoff. As with all herbs and extracts, you cant be sure exactly what youre getting and how effective the product may be.

Dosage recommendations vary depending on your current health and symptoms, but most resveratrol supplements are typically taken in about 250 to 500 milligrams/day dosages. Its important to point out that this is generally lower than the amounts that have been shown to be beneficial in studies, but its not clear if taking very high doses is safe.

Some adults choose to consume up to two grams daily (2,000 milligrams). (8) According to the New York Academy of Sciences, studies have found resveratrol to be safe and reasonably well-tolerated at doses of up to five grams per day, but this shouldnt be taken without speaking with your doctor. (9)

Its possible, however, to experience mild to moderate side effects at higher doses, so experts recommend starting with less until further studies demonstrate any added benefit of taking more. Resveratrol supplements may potentially interact with blood thinners like warfarin (Coumadin) and NSAID pain relievers (like aspirin or Advil), so be sure not to mix these.

Resveratrol works by modifying inflammation in the body, in addition to having other positive effects on hormone production, blood circulation and fat storage. Studies demonstrate that itspecifically seems to work in some of the following ways:(10)

Now you know the benefits of resveratrol in your diet, you may be wondering what the best source of this compound is. Below are the best foods and beverages to add to your diet (albeit in moderation) in order to consume more resveratrol:

Different plants supply various forms of resveratrol. For example grapes, peanuts and Itadori tea contain mainly trans-resveratrol glucosides. Red wine is primarily a source of the aglycones cis- and trans-resveratrol.

Studies show that both Itadori tea and red wine supply relatively high concentrations of resveratrol compared to most other foods. Itadori tea is a good option for people who avoid drinking alcohol or for children.

Although we have mentioned that red wine and cocoa are two of the best sources of resveratrol, unfortunately a diet of dark chocolate and red wine may be decadent but ultimately very unhealthy if you overdo it. The best way to obtain the benefits of resveratrol is through balance and moderation.

We recommend consuming wine in small amounts, about one glass per day or less; according to most research, up to two glasses daily for men and one per day for women hasnt been shown to cause any health concerns. If you do choose to take resveratrol supplements, still aim to consume antioxidants naturally from a healthy diet, including a variety of fresh plant foods.

While a large body of evidence has already suggested that resveratrol has many benefits, many experts feel that before we can promote drinking more wine or taking supplements to all adults, additional research is still needed. Overall, theres support for its positive attributes, but data is still needed to confirm its effectiveness for prevention of actual diseases in humans.

Its still not completely known how different people react to resveratrol and if some benefit more than others. For example, people with existing cases of diabetes or metabolic defects may need to take higher doses than mostly healthy adults to get the same effects. Talk to your doctor if you plan on taking supplements and are already on other medications.

Overall, most of the benefits of resveratrol have been shown in animal studies and at high dosages. Harvard School of Public Health points out, The dose of resveratrol administered in experiments is always much higher than youd normally consume in a daily diet. You would need to drink a hundred to a thousand glasses of red wine to equal the doses that improve health in mice. (11)

That being said, resveratrol is not a cure-all and means to living a longer, disease-free life. It may be one piece of the puzzle, but the bottom line is that it probably shouldnt motivate you to drink more wine than you already are.

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Health benefits of resveratrol: Evidence from clinical studies

Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in over 244 clinical trials, with an additional 27 clinical trials currently ongoing. Resveretrol is reported to potentially improve the therapeutic outcome in patients suffering from diabetes mellitus, obesity, colorectal cancer, breast cancer, multiple myeloma, metabolic syndrome, hypertension, Alzheimer's disease, stroke, cardiovascular diseases, kidney diseases, inflammatory diseases, and rhinopharyngitis. The polyphenol is reported to be safe at doses up to 5 g/d, when used either alone or as a combination therapy. The molecular basis for the pleiotropic activities of resveratrol are based on its ability to modulate multiple cell signaling molecules such as cytokines, caspases, matrix metalloproteinases, Wnt, nuclear factor-B, Notch, 5'-AMP-activated protein kinase, intercellular adhesion molecule, vascular cell adhesion molecule, sirtuin type 1, peroxisome proliferator-activated receptor- coactivator 1, insulin-like growth factor 1, insulin-like growth factor-binding protein 3, Ras association domain family 1, pAkt, vascular endothelial growth factor, cyclooxygenase 2, nuclear factor erythroid 2 like 2, and Kelch-like ECH-associated protein 1. Although the clinical utility of resveratrol is well documented, the rapid metabolism and poor bioavailability have limited its therapeutic use. In this regard, the recently produced micronized resveratrol formulation called SRT501, shows promise. This review discusses the currently available clinical data on resveratrol in the prevention, management, and treatment of various diseases and disorders. Based on the current evidence, the potential utility of this molecule in the clinic is discussed.

Keywords: chronic diseases; clinical trial; nutraceutical; pharmacokinetics; resveratrol.

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Pop the cork to unlock the health benefits of red wine – Lifestyle Asia India

Moderate wine consumption is believed to have several advantages. Health benefits of red wine aside, unwinding with a cold glass of the beverage after a hectic day is like a much-needed hug for the soul. Right from Biblical times, wine has been presented as a sacred elixir which is healing, soothing and even life-giving. This, probably, makes it one of the most loved alcoholic beverages worldwide. The benefits of red wine are thus something you should know about.

A glass of red wine is like a best friend we cant do without owing to its versatility. A reliable party companion, a key ingredient in your signature recipe, a therapist and a confidante drinking red wine can mean different things to different people.

However, knowing the right bottle of red is a form of art, which sommeliers spend decades mastering by unravelling the mystery behind this deep, richly textured magic potion. But in addition to its major cultural relevance, its also touted to have health benefits, while avoiding excessive drinking.

Making, ageing and preserving wine is an art which has been perfected for over 8,000 years. While there have been changes in the types of equipment used with innovative technology, the basic method remains true to its origin. Specially cultivated grapes go through around 12 steps before reaching your table in a rich, red, consumable form.

A special variety of black (or purple) grapes rich in anthocyanin gives red wine its signature red colour. They are harvested when perfectly ripe and prepared for fermentation. Harvesting grapes for wine is the primary step in winemaking as well as for cultivators who own some of the best vineyards.

Then, the grapes are taken to the winery where yeast is added to the fermentation process a crucial stage of red winemaking. This process is critical for the wines colour, texture and aroma. Different methods are employed to extract the flavours from grape skins and other fermenting elements.

The grapes are then transferred to a press. Making red wine is a little more complicated because the pressed grape liquid goes through fermentation once again while they are stored in barrels and containers of different types. The quality of red wine depends on how well it has been aged and rested.

Winemakers do a final blending of two or more grape liquids, which gives the wine a more nuanced taste. Each red wine type be it Shiraz, Merlot, Cabernet Sauvignon, Zinfandel or Pinot Noir gets its unique texture and flavour from such processes. The liquid is then filtered and bottled. At this stage, bottled wine is aged again in a cellar before it is ready to be consumed.

It is believed by some that moderate drinking of red wine should no longer be a guilty pleasure, as it has several health benefits.

Resveratrol, an antioxidant found in the skins of black grapes used to make red wine, might be linked to reducing heart diseases. It is touted that drinking red wine can reduce bad cholesterol and the subsequent formation of blood clots in the body.

A Science Direct report (2005) claims that this antioxidant does not directly reduce the risk of cardiovascular diseases but the resveratrol present in it may prevent damage to blood vessels along with another compound procyanidins found in the grapes. Reports studying the implication of red wine on cardiovascular health suggest that people who generally consume antioxidant-rich whole foods with a light to moderate quantity of red wine have decent heart health.

An NCBI report (2021) states that by drinking red wine in moderation, useful compounds are secreted in blood flow which in turn make positive changes in our bodys metabolic profile with an increase in fatty acids, cholesterol, branched-chain amino acids, ketone bodies, bacterial co-metabolites and cellular antioxidants. The report adds that drinking red wine might increase your longevity by seven percent.

Another red wine health benefit is associated with the improvement of gut bacteria in the body. A 2015 Medical News Today study states that resveratrol found in red wine is a natural phytoalexin, which encourages the formation of good gut bacteria which act like probiotics. The research is still ongoing to unlock the maximum health benefits of red wine on the gut.

This one is a bit of a paradox because excessive alcohol consumption is linked to an increase in depression. Still, studies show that moderate red wine consumption on a daily basis can help in beat stress and put you in a relaxed mood.

Resveratrol seems to be the magic ingredient found in red wine, as it is also linked to preventing cancer. Drinking red wine in moderation can unlock protective elements present in resveratrol, which work against the growth of cancer cells in the body. Though regular alcohol consumption raises breast cancer risk, red wine is an exception to this. Red wine has the opposite effect when consumed in moderation as reported by researchers from Cedars-Sinai Medical Center in Los Angeles in the Journal of Womens Health.

A BMJ medical report published in 2018 states that individuals who have never consumed alcohol, especially red wine, are at an increased risk of disorders including dementia and Alzheimers. One of the major health benefits of polyphenols, found in red wine, is that it has neuroprotective qualities. Thus, moderate red wine consumption might actually be helpful.

While sipping wine has been associated with wellness, in addition to relieving emotional stress, the key, as confirmed by research, is moderate red wine consumption. To get the most health benefits from this evergreen drink, doctors suggest that both men and women should limit their red wine consumption to two glasses per day. Additionally, individuals with a medical condition or seeking treatment for the same should consult their doctors before drinking red wine or any alcohol, as it can have counterproductive effects on their health.

Hero Image Credit: Kelsey Knight/Unsplash; Featured Image Credit: Rikkia Hughes/Unsplash

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What 6 Over-50 Beauty Experts Do to Treat Their Own Skin – NewBeauty Magazine

New York dermatologist Doris Day, MD

Significant Changes:I increased hydration and added higher-gradepeptides.

Go-to Products:I am always testing products but ingredients Istick to include growth factors,antioxidants, resveratrol, retinol, niacinamide and hyaluronic acid. There are always new ingredients and formulas Im working on, right now Im looking at ones that help support and nourish a healthy skin biome.

Favorite Treatments:My go-to treatments include a Sofwave ultrasound skin tightening treatment twice a year, neuromodulator injections about three times a year and a little filler touch up once a year.

Best Advice:Sun protection every day. Youre never too old or too young to protect your skin. Also see a great dermatologist to make sure you have a plan to keep your skin healthy and beautiful. Finally, see a functional medicine doctor or gynecologist who specializes in hormone replacement. It will help preserve collagen in your skin, as well as reduce other risks of aging.

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Peanuts: Best guide to learn health benefits, nutrition and side effects – PINKVILLA

Every person around the globe is aware of peanuts - crunchy and tiny nuts. These nuts or legumes make a mouth-watering side meal and come in handy whenever you are craving a delicious snack, especially during fasting and weight loss routine.

Peanuts are super rich in several minerals, micro and macro-nutrients, and vitamins, are highly affordable, and are a versatile ingredient - when compared to any other variety of nuts. Either raw or roasted, whatever form you choose to consume these tasty nuts, one thing is for sure - that you will end up with loads of health benefits, including strong heart health, beautiful skin, shiny hair, energy boost, and a good night's sleep.

Hence, this article. Today, we will talk about everything related to peanuts - from its definition, types, and nutritional facts to health benefits and also potential risks (if consumed in a heavy dose regularly).

Grab a handful of peanuts while you give this article a read. Let's start!

Peanuts are a type of legume that are surprisingly related to lentils, beans, and soy, and not to tree nuts.

Peanuts (Arachis hypogaea) originated in South America and are known by a variety of names, like earthnuts, groundnuts, and goobers.

The most popular type of peanut consumption is either raw (along with a pinch of tangy, salty powder) or in the form of peanut butter (both smooth and crunchy).

Yes, you read that right. Peanuts have a variety, as per the National Peanuts Board. There are four types of Peanuts -

With big kernels and premium characteristics, this type of peanut is known as a gourmet peanut. Due to their large size and pretty form, Virginia peanuts are best suited for snacking. This variety of peanuts is grown in Virginia, Carolinas, Texas, Florida, Oklahoma, Georgia, and New Mexico regions.

Runner peanuts are widely used to prepare peanut butter and other such confections. This type of peanut makes up 80% of the peanuts grown in the U.S.

With a slightly sweet flavor profile, Valencia peanuts make for all-natural peanut butter and an excellent boiled snack. This type of peanut makes up lesser than 1% of the peanuts grown in the U.S. and is mainly grown in the New Mexico and Texas regions.

The type of Peanuts with red skins and a nutty flavor profile is called Spanish peanuts. They are mainly consumed after roasting and have a slightly higher oil content, which adds depth to their overall nutty flavor. They are usually grown in New Mexico, Oklahoma, and Texas regions and are widely used in confections, candy, and peanut butter.

Peanuts are loaded with high-quality protein and healthy fats. Here is the nutrition profile for 3.5 ounces (100 grams) of raw Peanuts -

1. Calories (or Energy) = 567 kcal

2. Water content = 7%

3. Fat = 49.20 gm

4. Omega-3 = 0 gm

5. Omega-6 = 15.560 gm

6. Macronutrients:

7. Minerals:

8. Vitamins:

9. Fat:

Apart from these, Peanuts also contain a rich amount of biotin and copper - all of which are essential to reduce the risk of multiple ailments and maintain body metabolism.

Peanuts are versatile, flavorsome, and jam-packed with crucial nutrients, offering numerous health benefits, including supporting heart health, promoting muscle growth, losing weight, enhancing sexual function, etc. A plethora of health benefits of Peanuts as discussed below -

Consuming Peanuts every day in moderation helps those who are aiming to shed some extra kilos. Although Peanuts have a high-calorie level, they are all good fats. Add this to the high protein content, and Peanuts become great for weight loss by providing high satiety value. Not to forget that eating more protein reduces the level of Ghrelin, a-k-a, the hunger hormone, in your body. Thus, increasing the production of Peptide YY (a hormone which is responsible to make you feel full). Therefore, preventing you from binge eating.

Multiple studies have proven that consuming Peanuts tends to decrease the chances of heart diseases. Peanuts consist of nutrients that are crucial for having a healthy heart. These nuts contain copper, magnesium, protein, antioxidants (like Resveratrol), a healthy ratio of unsaturated and mono-unsaturated fats, and fiber that altogether help in reducing your bad cholesterol levels. Peanuts also contain antioxidants and amino acids that keep the inner lining of your arteries safe, thereby protecting your heart against heart problems like atherosclerosis. Also, as per a research published in the New England Journal of Medicine, a daily dose of these crunchy nuts reduces the risk of death from heart disease by 29%.

Peanuts consist of antioxidants (like Resveratrol) and mono-unsaturated fats that make your skin clear. These nutrients also wash away all the toxins from your body that make your skin appear dull, greasy, and lifeless. The antioxidant, Resveratrol, even delays the signs of aging, including fine lines, wrinkles, and dark spots. Additionally, this antioxidant is a scientifically proven cure for skin diseases like Eczema and Psoriasis.

Research shows that Vitamin E and Vitamin C present in the Peanuts protect your skin against the harsh UV rays of the Sun from causing any subsequent damage. Plus, the presence of Vitamin C also gives elasticity to your skin, making it look brighter, younger, and smoother.

To keep your brain healthy, active, and sharp, you obviously require rich nutrients like Vitamin B1, Folate, and Niacin. When you include Peanuts in your daily meal, your body tends to fuel up with these nutrients. And as a result, your brain becomes more active, healthy, and sharp. Vitamin B1 and Niacin also help to protect your brain against diseases like Alzheimers and age-related cognitive decline. Moreover, Peanuts are jam-packed with a bioactive antioxidant called Resveratrol, which improves verbal fluency and cognitive abilities in people. Also, Polyphenols present in Peanuts are called mood food that helps against cognitive and psychiatric disorders, which, in turn, keeps your brain healthy.

The requirement of protein necessary for the proper and healthy growth of children can be fulfilled by eating Peanuts on a daily basis. Peanuts are loaded with protein, making about 22% to 30% of their total calories. This protein helps in building muscle mass while promoting muscle growth and supporting bone health. Plus, adequate protein intake also helps to speed up any wound healing. Additionally, adding Peanut butter spread on toast or crackers makes a great and super tasty pre-workout or mid-day snack while adding to your total protein intake.

Aging in people causes the weakening of many bones present in your body. Therefore, before your bones start losing their agility and strength, you must focus on eating healthy and nutrient-rich food options like Peanuts. Plus, Peanuts are rich in phosphorus and manganese. These nutrients and other essential Vitamins that are present in Peanuts help to keep up and maintain the strength of your bones, thereby assisting you in your old age.

When it comes to the maintenance of your eye health, a few green leafy vegetables and Peanuts are considered the best food items that you should consume. The presence of Zinc in Peanuts helps your body to transfer Vitamin A, which is highly crucial for clear and healthy eyesight and vision. Also, the presence of Vitamin E in Peanuts helps to slow down cataract formation and any other age-related macular degeneration or illness.

Peanuts are super rich in an essential amino acid, Arginine, that has been studied extensively and thoroughly as a possible treatment and cure for erectile dysfunction. However, there is still more research required to understand if Arginine alone can help to treat erectile dysfunction. But, research analyses confirm that oral administration of this amino acid when combined with a herbal supplement, Pycnogenol, may help in the treatment of erectile dysfunction.

Peanuts are a great source of healthy fats that mostly come from Oleic acids, which are also found in olive oil. This particular acid present in the Peanuts truly helps to fight against inflammation and other free radicals in your body cells.

Since Peanuts have no sugar content, they are completely safe for all diabetic patients. Plus, these nuts are a rich source of vital nutrients and are truly delicious at the same time. Also, research shows that eating Peanuts (especially in the morning) can help you to keep a check on your blood sugar level throughout the day. And it may also prevent insulin spikes to some extent if and when you eat sugary foods. As per a research study by The American Medical Association, regular (and controlled) consumption of Peanuts actually strengthens your bodys natural ability to regulate and maintain its insulin levels against Type 2 diabetes.

Thorough researches have shown that consuming Peanuts can reduce the risk of cancer. Plus, Peanuts have an excellent amount of Vitamin E and protein that helps to lower the risk of cancer. Also, these legumes have a good content of antioxidants like Resveratrol, which further helps in preventing cancer by cutting off the blood supply to your growing cancer and restraining cancer cell growth.

Around 25% of adults suffer from gallstones - a disease caused by uncontrolled levels of bad cholesterol - every year. Since Peanuts control cholesterol levels, eating an adequate amount of Peanuts may reduce the risk of gallstones in adults as well as in children.

Peanuts are jam-packed with an amino acid, Arginine, that is converted into Nitric Oxide - a compound that helps to dilate your blood vessels to improve overall blood flow and circulation. Studies show that taking Arginine supplements may help in the treatment of mild to moderate erectile dysfunction, enhancing sexual function. Other test-tube studies have found that Arginine can also enhance libido, improve semen quality, and increase your overall testosterone levels. Additionally, Peanuts are a very good source of antioxidants like Resveratrol that have proven to support and enhance sexual health in men by improving erectile function and sperm quality. However, more research is still needed to determine if Peanuts specifically can affect sexual function.

Contrary to a popular belief (rather a myth), adding Peanuts or Peanut butter to your meal does not spike your blood sugar levels. Rather, having them alongside your meal high in GL (like a glass of juice or a savory bagel) may actually stabilize your blood sugar levels. That is probably the reason why the American Diabetes Association names Peanuts among the diabetes-friendly superfoods. Furthermore, the fiber content found in Peanuts also helps to lower your blood sugar levels. And these nuts also contain magnesium and several other healthy oils that play a vital role in managing, controlling, and balancing your blood sugar levels.

Eating Peanuts daily in an adequate amount is healthy and good, but overeating them obviously may backfire just like with any other food. However, aside from Peanut allergies, eating them has not been linked to many severe adverse effects. Still, below are some possible side effects of Peanuts that you should consider and know.

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Brad Pitt’s New Skin Care Line Inspired by Wine: What Experts Think – Healthline

Brad Pitt is getting a taste of the beauty industry with a new skin care line that promises to help people age like fine wine.

The new line, Le Domaine, is a joint effort between Pitt and organic wine growers the Perrin family. The products include creams and serums and cost between $80 to $385 and come in small bottles made of recycled glass made with re-purposed parts of wine barrels.

Le Domaine purports to have uncorked the secret to slowing aging with a pair of exclusive, patented active ingredients. The first, GSM10, is made, in part, from a marc from grenache seeds and syrah seeds. The lines website says these ingredients work to stop collagen destruction, have antioxidant properties, and balance the skin.

The second, ProGR3, is said to reduce visible signs of aging by using natural molecules found in plant extracts, vine cuttings, chamomile, and green tea.

Though the line touts graceful aging benefits, Pitt interestingly debunked the idea that you can stop the clock in an interview.

I dont want to be running from aging, Pitt said while discussing the line with Vogue. Its a concept we cant escape, and I would like to see our culture embracing it a bit more, talking about it in those terms.

Ultimately, Dr. Viktoryia Kazlouskaya, a dermatologist with Khrom Dermatology, Brooklyn, N.Y., says approaches to physical signs of aging are as varied as tastes in wine. Some feel young inside and want their appearance to match that. Others see lines and wrinkles as signs of a well-lived life, and others prefer a blend.

Either approach reflects the expression of the authentic self, as authenticity means different things for different people, Kazlouskaya says. There is no shame in a desire to match the inner energy with the outer, and anti-aging practices will stay with us for the years ahead.

But will Pitts new foray into beauty help people who want to slow the signs of aging? Heres what dermatologists and researchers say.

Pitts active ingredients are new. But some of the components of them, like the syrah seeds, are inspired by wine.

Wine, particularly red, has a reputation for providing some health benefits, including to the skin. But the recent evidence is contradictory.

In fact, research from 2019 indicated that drinking wine could increase signs of facial aging, including undereye puffiness. However, the plant compound resveratrol, found in red wine, may help fight cell damage, an older 2010 review suggested.

But what about the topical use of some of these ingredients?

Lets start with those found in GSM10. Though no peer-reviewed studies exist on it, one expert says the gape seed extract may have some promise.

Grape seeds are known to be rich in polyphenols which are molecules that have antioxidant and anti-inflammatory properties, says Dr. Emily Wood, a board certified dermatologist, at Westlake Dermatology in Austin.

A 2020 review pointed to research that grapeseed extracts had anti-inflammatory properties and might have benefits that support aging gracefully. An older 2011 study of mice indicated that grape seed extract might reduce sun damage, a key trigger for premature aging.

Similarly, the components of ProGR3 do have some research behind them.

A pair of smaller studies one from 2005 and another from 2013 suggest green tea extract could slow skin aging.

A 2010 study indicated chamomile oil application could reduce atopic dermatitis in mice, while one from 2018 suggested application could aid wound healing. Though neither study on chamomile mentioned aging, one expert believes that, like green tea, the properties suggest it could help.

Both green tea and chamomile address signs of aging topically and when ingested, says Dr. Reid Maclellan, the founder and CEO of Cortina, adjunct Faculty at Harvard Medical School, and director of Proactive Dermatology Group. Both teas are antioxidant-rich and within, have a biological compound called polyphenols which work to destroy free radicals and slow the progression of aging.

Maclellan says the decision to use vine cuttings may be because of the research behind resveratrol. Research, like a 2019 review, suggests it has antioxidant properties to slow photoaging and protect against oxidative damage, such as from UV radiation.

Could all of these components, combined, team up to fight the signs of aging? The jury is out.

The key question is whether or not these extracts are actually permeating the epidermis due to the fact that polyphenols are hydrophilic, and the top layer of the skin has a high lipid content, says Wood. Think of the simple kitchen experiment of mixing oil and water together. Similar principles are at play when we think of drug delivery to the skin. The vehicle of delivery is key when looking at achieving effective penetration.

As a consumer, Kazlouskaya understands the interest in the new line.

On an emotional level, I already see myself opening this beautifully designed box containing a classy-looking jar with a massive oak wood cap, she says.

But as a dermatologist, Kazlouskaya is trained to step back and look at the whole package mainly, the evidence behind the ingredients. Thats where shes not sold on the touted benefits of the new line. She says she wants to know:

Wood has similar thoughts. She loves the elegant packaging and the fact that its made from recycled materials. But she cant judge a product by its recycled wine barrel cover.

There is some solid science backing the idea of utilizing plant-derived polyphenols to decrease signs of aging, Wood says. However, more studies need to be conducted on the effectiveness of topical polyphenols and in which vehicles of delivery these molecules will effectively penetrate the epidermis.

Though aging is a natural process that cannot be stopped, experts say some of its effects can be slowed.

Though its not as easy as 1-2-3, Dr. Jeremy Fenton of Schweiger Dermatology Group in NYC has simplified his advice for patients looking for products that help reduce the signs of aging into a three-step process:

1. Sunscreen

2. Retinoid or retinol (if your skin can tolerate it)

3. Topical antioxidant products/serums

The American Academy of Dermatology Association recommends using a broad-spectrum sunscreen of at least SPF 30 or above and reapplying every two hours when exposed to the sun to protect against aging and skin cancer.

Research from 2019 suggests retinoid, a derivative of vitamin A, has skin care benefits, including anti-wrinkle properties.

Fenton says vitamins C and E are two of the antioxidant ingredients found in some serums and products he suggests patients look into.

A 2020 review suggests the use of vitamins C and E could also reduce the signs of aging.

Kazlouskaya agrees about sunscreen, retinol/retinoids, and antioxidants. Though there always seems to be a new ingredient or product on the block, she says less is often more.

I learned to be a minimalist after treating numerous patients with rosacea and sensitive skin, as more does not mean better, she says.

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Brad Pitt's New Skin Care Line Inspired by Wine: What Experts Think - Healthline

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