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Category Archives: Pharmacogenomics

Genetics and Pharmacology | YourHub – The Know

Ever had a bad experience with a prescription?

Ever thought it was an allergic reaction to a medication?

In 2017 I had a significant abdominal surgery that required me to take pain medication, anti-inflammatories, and antibiotics. The surgery was supposed to help with a significant abdominal umbilical hernia. It occurred on a Wednesday, and by Monday, I was having a significant reaction to the pain medication, where my FACE went NUMB. Talk about scary.

Leading up to the surgery, I had taken part in 2 appointments where I discussed previous bad reactions to the pain medication and talked about my concerns. They told me it was a necessary evil in this case so that I could sleep. The morning of surgery, after long discussion with the anesthesiologist, He asked if I had testing done to look at my response to different drugs. At that time, I didnt even know that was a thing that could be done.

The news media and medical media lately has talked a lot about epigenetics and epigenomics and we are starting to hear about pharmacogenetics. Pharmacogenetics can be done through DNA testing to specifically look at your genetics and how they might react to specific types of drugs. They can allow for better dosing, better drug choice so there is less guess work, and overall better outcomes. Pharmacogenetics can also help in looking at how some people may become addicted and others not to things like marijuana, which the Prop 64 group in Colorado would have us believe is not possible.

Pharmacogenetics can also let us know when it might be time to change a drug, because the epigenetics/epigenomics, or the environmental factors that cause the genes to change may have been affected over long-term use of specific drugs. These drugs can be related to addiction treatment, pain management, mental health disorders (bipolar, schizophrenia, depression), autoimmune logical drugs including chemotherapy.

Along the line of epigenetics/epigenomics, there is a specific testing that can be done that supports your DNA sections. It looks at what will optimally support your health, and with that information we can create a supplement that is SPECIFIC to you. Repeating the test about 6 months after initial testing and consuming of those supplements is recommended due to the changes you could potentially make. Then every year.

Why would you need a DNA-specific supplement? Colorado has one of the highest levels of radiation exposure in the continental U.S. Specifically, we have a lot of naturally occurring uranium and radon. Both of those are known carcinogens. Also, think about how much and what type of sunscreen you apply every year in Colorado while enjoying the outdoor lifestyle you love. Chemical barriers are more likely to interact with the radiation from the sun to create mutation of cells. It starts at the skin level, but quickly spreads to the body as the skin is an organ that ABSORBS things you put on it.

If you have questions about how DNA testing can improve your health, life and longevity, dont hesitate to reach out!



*Recent developments in genetic/genomic medicine, Rachel H. Horton and Anneke M. Lucassen, Clin Sci (Lond). 2019 Mar 15; 133(5): 697708.Published online 2019 Mar 5. Prepublished online 2019 Feb 27. doi: 10.1042/CS20180436

*Pharmacogenomics in the treatment of mood disorders: Strategies and Opportunities for personalized psychiatry; Azmeraw T. Amare,1 Klaus Oliver Schubert,1,2 and Bernhard T. Baune1; EPMA J. 2017 Sep; 8(3): 211227.Published online 2017 Sep 5. doi: 10.1007/s13167-017-0112-8*Future Trends in the Pharmacogenomics of Brain Disorders and Dementia: Influence of APOE and CYP2D6 Variants; Ramn Cacabelos,1,2,* Luca Fernndez-Novoa,1,2 Roco Martnez-Bouza,1,2 Adam McKay,1,2 Juan C. Carril,1,2 Valter Lombardi,1,2 Lola Corzo,1,2 Ivn Carrera,1,2 Ivn Tellado,1,2 Laura Nebril,1,2 Margarita Alcaraz,1,2 Susana Rodrguez,1,2 ngela Casas,1,2 Vernica Couceiro,1,2 and Antn lvarez1,2Pharmaceuticals (Basel). 2010 Oct; 3(10): 30403100.Published online 2010 Sep 29. doi: 10.3390/ph3103040*Some observations on the role of environment and genetics in behaviour of wild and domestic forms of Sus scrofa (European wild boars and domestic pigs)S Robert, J Dancosse, A Dallaire Applied Animal Behaviour Science, 1987 Elsevier

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Genetics and Pharmacology | YourHub - The Know

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Global Strategic Analysis of the Personalized Medicine, Targeted Therapeutics and Companion Diagnostic Market 2020-2025 – GlobeNewswire

Dublin, June 12, 2020 (GLOBE NEWSWIRE) -- The "Personalized Medicine, Targeted Therapeutics and Companion Diagnostic Market to 2025 - Strategic Analysis of Industry Trends, Technologies, Participants, and Environment" report has been added to's offering.

This comprehensive report examines the precision medicine industry and its impact on the health system. This report tackles the growing market interest in pharmacogenomics, targeted therapeutics, companion diagnostics, and the associated market environment.

This report describes the current technologies that are propelling the personalized medicine and companion diagnostic market. It examines the current genetic diagnostic tests and companion diagnostic assays that are in use by the medical and pharmaceutical industry today. Current developments in personalized medicine and the pharmacogenomics revolution are discussed. The emerging trends that appear in key markets such as the US, UK, Germany, and France are elucidated and analysed. This study reveals market figures of the overall personalized medicine market and also sub-market figures.

The study also provides a comprehensive financial and product review of key players in the personalized medicine industry. Strategic drivers and restraints of this market are revealed and market opportunities and challenges are identified.

In summary, the personalized therapeutic and associated companion diagnostic market have huge opportunities for growth. This industry is revolutionizing the healthcare system and will improve therapeutic effectiveness and reduce the severity of adverse effects. It has enormous potential for investment and the emergence of genetic-based in vitro diagnostics. This is a comprehensive account of the market size, segmentation, key players, SWOT analysis, influential technologies, and business and economic environments.

The report is supported by over 360 tables & figures over 470 pages. The personalized medicine market is presented as follows:

A wealth of financial data & business strategy information is provided including:

SWOT, Economic & Regulatory Environment specifics include:

This report highlights a number of significant players and influential company's and gives details of their operations, products, financials and business strategy:

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Global Strategic Analysis of the Personalized Medicine, Targeted Therapeutics and Companion Diagnostic Market 2020-2025 - GlobeNewswire

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The Global In- vitro diagnostics market is poised to grow at a CAGR of around 5.5% by 2028 – Yahoo Finance UK

Some of the prominent trends that the market is witnessing are growing healthcare expenditure in the emerging markets, huge demand for technologically advanced testing methods, raising incidences of chronic disease and growth opportunities/investment opportunities.

New York, June 17, 2020 (GLOBE NEWSWIRE) -- announces the release of the report "Global In-Vitro Diagnostics Market Analysis & Trends - Industry Forecast to 2028" -

Based on product the market is categorized into data management software, reagents & kits, instruments, software and services and consumables.

By application the market is segmented into cancer, cardiac diseases, infectious disease, drug testing/pharmacogenomics, cardiology, diabetes, nephrology, HIV/AIDS, autoimmune diseases and other applications.

Depending on technology the market is segregated by Molecular Diagnostics (MDX), immunochemistry/immunoassays, clinical chemistry, clinical microbiology, coagulation and haemostasis, haematology and other IVD technologies. Furthermore molecular diagnostics (MDX) is segmented by polymerase chain reaction (PCR), hybridization, isothermal nucleic acid amplification technology (INAAT), microarray, DNA diagnostics and other MDX technologies.

Immunochemistry/Immunoassays are divided into enzyme-linked immunosorbent assay (ELISA), western blot, rapid tests, radioimmunoassay (RIA) and enzyme-linked immunospot (Elispot) assay. Clinical chemistry is categorized into liver panel, renal profile, electrolyte panel, basic metabolic panel, thyroid function panel and specialty chemical tests.

This industry report analyzes the market estimates and forecasts of all the given segments on global as well as regional levels presented in the research scope. The study provides historical market data for 2017, 2018 revenue estimations are presented for 2019 and forecasts till 2028. The study focuses on market trends, leading players, supply chain trends, technological innovations, key developments, and future strategies. With comprehensive market assessment across the major geographies such as North America, Europe, Asia Pacific, Middle East, Latin America and Rest of the world the report is a valuable asset for the existing players, new entrants and the future investors.

The study presents detailed market analysis with inputs derived from industry professionals across the value chain. A special focus has been made on 23 countries such as U.S., Canada, Mexico, U.K., Germany, Spain, France, Italy, China, Brazil, Saudi Arabia, South Africa, etc. The market data is gathered from extensive primary interviews and secondary research. The market size is calculated based on the revenue generated through sales from all the given segments and sub segments in the research scope. The market sizing analysis includes both top-down and bottom-up approaches for data validation and accuracy measures.

This report provides data tables, includes charts and graphs for visual analysis.

Regional Analysis: North America - US - Canada - Mexico

Europe - France - Germany - Italy - Spain - UK - Rest of Europe

Asia Pacific - China - Japan - India - Australia - New Zealand - Rest of Asia Pacific

Middle East - Saudi Arabia - UAE - Rest of Middle East

Latin America - Argentina - Brazil - Rest of Latin America

Rest of the World - Africa - Caribbean

Report Highlights: - The report provides a detailed analysis on current and future market trends to identify the investment opportunities - Market forecasts till 2028, using estimated market values as the base numbers - Key market trends across the business segments, Regions and Countries - Key developments and strategies observed in the market - Market Dynamics such as Drivers, Restraints, Opportunities and other trends - In-depth company profiles of key players and upcoming prominent players - Growth prospects among the emerging nations through 2028 - Market opportunities and recommendations for new investmentsRead the full report:

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The Global In- vitro diagnostics market is poised to grow at a CAGR of around 5.5% by 2028 - Yahoo Finance UK

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What You Need to Know About COVID-19 Testing – Touro College News

When you were at Roche, you developed an automated diagnostic testing platform that is now used for COVID-19 testing. Can you explain it?

The system is based on polymerase chain reaction, PCR for short, which uses a series of temperature cycles to make multiple copies of a specific DNA or RNA sequence. Early PCR testing required lots of human intervention, which limited its use outside of research settings. The system we developed can perform the necessary steps automatically, and can process 960 samples at once, with results in eight hours. The U.S. Food and Drug Administration has approved tests that run on the system for HIV, tuberculosis and many other pathogens, and approved a test for SARS-CoV-2, the virus that causes COVID-19, in mid-March.

What is an antibody test? Should anyone get one?

Also called serological tests, these check a persons blood for antibodies to COVID-19. If a person tests positive, they have been exposed to the virus, while a negative test means they havent been exposed. Public health authorities are now trying to perform as many antibody tests as possible, which gives them an idea of the level of exposure to the virus within the population.

How reliable is COVID testing and antibody testing?

COVID-19 testslike the Roche testare used to determine if a sick person has the virus. These test a sample thats taken by swab from the back of a persons throat, and are extremely reliable, as long as the sample was taken correctly. There have been problems with the reliability of antibody testing, largely because several products reached the market without FDA review.

How can someone be sure theyre getting a reliable test?

Ask if the test has been submitted for review to the FDA, and if it has been approved by the FDA. This is indicative of the comprehensiveness of the data supporting the validity of the test.

If I test positive, does that mean Im immune?

We still dont know whether people who make antibodies to COVID-19 will be immune to infection. Even if you have a positive antibody test, you should remain vigilant with social distancing and mask use.

Do you see a vaccine in the near future?

There is tremendous effort being dedicated to vaccine development in large global pharmaceutical companies as well as in biotechnology companies. I believe we will start to see a vaccine emerge by the end of this calendar year.

You hold more than 25 patents. Of which are you most proud?

Probably the early ones that focused on identifying variation in the human genome. The early work on DNA identity has served as the foundation for the exciting field of pharmacogenomics, which explores how genes affect drug response.

What did you do before coming to Touro?

I was a senior executive in the pharmaceutical / biotechnology industry. I was also involved in several biotechnology start-ups and held an adjunct appointment at Touros New York Medical College.

What You Need to Know About COVID-19 Testing - Touro College News

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Gymnastic Equipment Market 2019 | How The Industry Will Witness Substantial Growth In The Upcoming Years | Exclusive Report By MRE – Cole of Duty

The report covers analysis on regional and country level market dynamics. The scope also covers competitive overview providing company market shares along with company profiles for major revenue contributing companies.

The global Gymnastic Equipment Market report scope includes detailed study covering underlying factors influencing the industry trends.

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The report scope includes detailed competitive outlook covering market shares and profiles key participants in the global Gymnastic Equipment Market share. Major industry players with significant revenue share include Abo, AK Athletic Equipment, Bnfer, Continental Sports, Norberts Athletic Products, and others.

The global Gymnastic Equipment Market is segregated on the basis of distribution channel as DTC, Modern trade, Online, and VAR. Based on Application the global Gymnastic Equipment Market is segmented in Hospital, Clinic, and Others. Based on Application the global Gymnastic Equipment Market is segmented in Infectious Diseases, Diabetes, Oncology, Cardiology, Autoimmune Diseases, Drug Testing/Pharmacogenomics, HIV/Aids, Nephrology, and Other Applications.

The global Gymnastic Equipment Market report provides geographic analysis covering regions, such as North America, Europe, Asia-Pacific, and Rest of the World. The Gymnastic Equipment Market for each region is further segmented for major countries including the U.S., Canada, Germany, the U.K., France, Italy, China, India, Japan, Brazil, South Africa, and others.

Gymnastic equipment is intensely affected by an expansion in close to home interest in recreational sports exercises. The brisk face way of life of individuals has expanded the support of people engaged with different recreational exercises, and gymnastics is no exemption. Gymnastics as a recreational movement has increased huge footing as the number of individuals who want to take part in sports around the world over rises.

The expanding prominence of internet business directs to pick up footing in the market. The rising commonness of sedentary lifestyle and the absence of physical exercise are prompting a few physical and mental sicknesses, for example, diabetes, and hypertension, anxiety, obesity. Driven by the expanding familiarity with a healthy lifestyle. Moreover, there is a lofty increment in the number of individuals experiencing chronic back pain due to a lack of physical exercise. This will force individuals to concentrate on healthy fitness exercises which will drive the growth of the gymnastic equipment market globally.

Competitive Rivalry

Abo, AK Athletic Equipment, Bnfer, Continental Sports, Norberts Athletic Products, and others are among the major players in the global Gymnastic Equipment Market. The companies are involved in several growth and expansion strategies to gain a competitive advantage. Industry participants also follow value chain integration with business operations in multiple stages of the value chain.

The Gymnastic Equipment Market has been segmented as below:

Gymnastic Equipment Market, By Distribution Channel

Gymnastic Equipment Market, By Region

Gymnastic Equipment Market, By Company

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Gymnastic Equipment Market 2019 | How The Industry Will Witness Substantial Growth In The Upcoming Years | Exclusive Report By MRE - Cole of Duty

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Qualitative Analysis and Competitive Industry Scenario of Pharmacogenomics Market – Medic Insider

Prophecy Market Insights Pharmacogenomics market research report provides a comprehensive, 360-degree analysis of the targeted market which helps stakeholders to identify the opportunities as well as challenges. The research report study offers keen competitive landscape analysis including key development trends, accurate quantitative and in-depth commentary insights, market dynamics, and key regional development status forecast 2020-2029. It incorporates market evolution study, involving the current scenario, growth rate, and capacity inflation prospects, based on Porters Five Forces and DROT analyses.

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An executive summary provides the markets definition, application, overview, classifications, product specifications, manufacturing processes; raw materials, and cost structures.

Market Dynamics offers drivers, restraints, challenges, trends, and opportunities of the Pharmacogenomics market

Segment Level Analysis in terms of types, product, geography, demography, etc. along with market size forecast

Regional and Country- level Analysis different geographical areas are studied deeply and an economical scenario has been offered to support new entrants, leading market players, and investors to regulate emerging economies. The top producers and consumers focus on production, product capacity, value, consumption, growth opportunity, and market share in these key regions, covering

The comprehensive list of Key Market Players along with their market overview, product protocol, key highlights, key financial issues, SWOT analysis, and business strategies. The report dedicatedly offers helpful solutions for players to increase their clients on a global scale and expand their favour significantly over the forecast period. The report also serves strategic decision-making solutions for the clients.

Competitive landscape Analysis provides mergers and acquisitions, collaborations along with new product launches, heat map analysis, and market presence and specificity analysis.

Segmentation Overview:

PharmacogenomicsMarket Key Companies:

Thermo Fisher Scientific Inc., Qiagen N.V., F.Hoffmann-La Roche AG, Abbot Laboratories, Diatech Pharmacogenetics, and Assurex Health Inc.

The Pharmacogenomics research study comprises 100+ market data Tables, Graphs & Figures, Pie Chat to understand detailed analysis of the market. The predictions estimated in the market report have been resulted in using proven research techniques, methodologies, and assumptions. This Pharmacogenomics market report states the market overview, historical data along with size, growth, share, demand, and revenue of the global industry.

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The study analyses the manufacturing and processing requirements, project funding, project cost, project economics, profit margins, predicted returns on investment, etc. This report is a must-read for investors, entrepreneurs, consultants, researchers, business strategists, and all those who have any kind of stake or are planning to foray into the Pharmacogenomics industry in any manner.

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Qualitative Analysis and Competitive Industry Scenario of Pharmacogenomics Market - Medic Insider

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