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Category Archives: Pharmacogenomics

PGxOne Pharmacogenomics Test | Admera Health

ACE Inhibitors Benazepril (Lotensin) ACE Captopril (Capoten) ACE AGTR1 Perindopril (Aceon) ACE AGTR1 Quinapril (Accupril) ACE Angiotensin II Receptor Blockers Candesartan (Atacand) AGTR1 Irbesartan (Avapro) ACE Losartan (Cozaar) ABCB1 AGTR1 Antianginal Agent Ranolazine (Ranexa) CYP2D6 Antiarrhythmic Agent Amiodarone (Cordarone) CYP3A4 NOS1AP Digoxin (Lanoxin) ABCB1 Dronedarone (Multaq) CYP3A4 Flecainide (Tambocor) CYP2D6 Propafenone (Rythmol) CYP2D6 Anticoagulants Phenprocoumon (Marcoumar) CYP4F2 Rivaroxaban (Xarelto) CYP3A4 Warfarin (Coumadin) CYP2C9 VKORC1 Antiplatelets Clopidogrel (Plavix) CYP2C19 Ticagrelor (Brilinta) CYP3A4 Beta Blockers Atenolol (Tenormin) ADRA2A Carvedilol (Coreg) CYP2D6 Nebivolol (Bystolic) CYP2D6 Propranolol (Inderal LA) CYP2D6 Metoprolol Tartrate (Lopressor) CYP2D6 Calcium Channel Blockers Amiodarone (Cordarone) NOS1AP Amlodipine (Norvasc) CYP3A4 NOS1AP Diltiazem (Cardizem) CYP3A4 Felodipine (Plendil) CYP3A4 Lercanidipine (Zanidip) CYP3A4 Nifedipine (Adalat) NOS1AP Nisoldipine (Sular) CYP3A4 Nitrendipine (Nitrepin) AGTR1 CYP3A4 Verapamil (Calan) NOS1AP Diuretics Bumetanide (Bumex) ACE Furosemide (Lasix) ACE Hydrochlorothiazide (Microzide) ACE AGTR1 Spironolactone/HCTZ (Aldactazide) ADTR1 ACE Spironolactone (Aldactone) ACE Torasemide (Demadex) ACE Phosphodiesterase Inhibitors Cilostazol (Pletal) CYP3A4 Antilipemic Agent Atorvastatin (Lipitor) ABCB1 APOE CYP3A4 CYP3A5 KIF6 SLCO1B1 Fluvastatin (Lescol) ACE Lovastatin (Mevacor) CYP3A4 CYP3A5 Pitavastatin (Livalo) SLCO1B1 Pravastatin (Pravachol) KIF6 SLCO1B1 Rosuvastatin (Crestor) SLCO1B1 Simvastatin (Zocor) ABCB1 CYP3A4 CYP3A5 SLCO1B1 Atorvastatin/Ezetimibe (Liptruzet) ABCB1 APOE CYP3A4 KIF6 SLOC1B1 Fenofibrate (Tricor) APOE Simvastatin/Ezetimibe (Vytorin) ABCB1 SLCO1B1 Vasodilators Nitroprusside (Nipride) ACE Hydralazine NAT2 Hydralazine/Isosorbide (Bidil) NAT2 Miscellaneous Cardiovascular Agents Ivabradine (Corlanor) CYP3A4 ACE Inhibitors/Diuretics Quinapril/HCTZ (Accuretic) ACE AGTR1 Captopril/HCTZ (Capozide) ACE AGTR1 Benazepril/HCTZ (Lotensin HCT) ACE AGTR1 Lisinopril/HCTZ (Prinzide) AGTR1 Enalapril/HCTZ (Vaseretic) AGTR1 ARBs/Diuretics Candesartan/HCTZ (Atacand HCT) AGTR1 Irbesartan/HCTZ (Avalide) ACE AGTR1 Losartan/HCTZ (Hyzaar) AGTR1 ABCB1 Beta-Blocker/Diuretic Metoprolol/HCTZ (Lopressor HCT) CYP2D6 AGTR1 CCB/ACE Inhibitor Amlodipine/Benazepril (Lotrel) ACE CYP3A4 NO1SAP Continue reading



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PGxOne Pharmacogenomics Test | Admera Health

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Pharmacogenomics Market: Improving Healthcare Infrastructure in APAC Incrementing Demand – Edition Truth

Therapeutic applications such as cardiology, oncology, neurological disorder, and pain management will keep the global Pharmacogenomics Market in good stead in the near future. Continue reading



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Pharmacogenomics Market: Improving Healthcare Infrastructure in APAC Incrementing Demand - Edition Truth

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PHG Foundation – Interactive Tutorial: Pharmacogenomics …

Pharmacogenetics refers to the study of genetic influences on an individuals response to drugs. In pharmacogenetics, the analysis of a specific gene, or group of genes, may be used to predict responses to a specific drug or class of drugs. Pharmacogenomics refers collectively to all the genes that influence drug responses, and how genome-wide analysis may be used to identify such genes in the search for novel drug targets and/or key determinants of drug reactions Continue reading



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PHG Foundation - Interactive Tutorial: Pharmacogenomics ...

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MediMap genomics test – precision medicine at Inova …

Go to Inova Translational Medicine Institute Pharmacogenomics, also called PGx, combines the science of how medications work (pharmacology) with the science of how genetic differences can influence health (genomics).Inova is pleased to offer the MediMap PGx test to adults and children, as well asto newbornsdelivered atInova Womens Hospital. MediMap is part of the standard package of services offered to all babies born at Inova Womens Hospital located at Inova Fairfax Medical Campus, and it is therefore performed at no additional cost. Continue reading



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MediMap genomics test - precision medicine at Inova ...

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Pharmacogenetics – Wikipedia

Pharmacogenetics is the study of inherited genetic differences in drug metabolic pathways which can affect individual responses to drugs, both in terms of therapeutic effect as well as adverse effects.[1] The term pharmacogenetics is often used interchangeably with the term pharmacogenomics which also investigates the role of acquired and inherited genetic differences in relation to drug response and drug behavior through a systematic examination of genes, gene products, and inter- and intra-individual variation in gene expression and function.[2] In oncology, pharmacogenetics historically is the study of germline mutations (e.g., single-nucleotide polymorphisms affecting genes coding for liver enzymes responsible for drug deposition and pharmacokinetics), whereas pharmacogenomics refers to somatic mutations in tumoral DNA leading to alteration in drug response (e.g., KRAS mutations in patients treated with anti-Her1 biologics).[3] Much of current clinical interest is at the level of pharmacogenetics, involving variation in genes involved in drug metabolism with a particular emphasis on improving drug safety. The wider use of pharmacogenetic testing is viewed by many as an outstanding opportunity to improve prescribing safety and efficacy. Driving this trend are the 106,000 deaths and 2.2 Million serious events caused by adverse drug reactions in the US each year.[4][unreliable medical source?] As such ADRs are responsible for 5-7% of hospital admissions in the US and Europe, lead to the withdrawal of 4% of new medicines, and cost society an amount equal to the costs of drug treatment.[5] Comparisons of the list of drugs most commonly implicated in adverse drug reactions with the list of metabolizing enzymes with known polymorphisms found that drugs commonly involved in adverse drug reactions were also those that were metabolized by enzymes with known polymorphisms (see Phillips, 2001). Continue reading



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Pharmacogenetics - Wikipedia

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Internships Internship Search and Intern Jobs …

Internships.com is the worlds largest internship marketplace bringing students, employers andhigher education institutionstogether in one centralized location. We specialize in helpingstudentsand young professionals find the right internship to kick start their career. Its no secret that internships are the most effective way for students to gain work experience before graduation Continue reading



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Internships Internship Search and Intern Jobs ...

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