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Nanotechnology-enabled low-cost, point-of-care, self-test of sodium in the comfort of your home – Nanowerk

Apr 26, 2022(Nanowerk Spotlight) Researchers from the Central University of Kerala, India, have developed a point-of-care, portable, rapid, and cost-effective test for clinical diagnosis of sodium, which uses a paper printed colorimetric sensor that is based on Curcumin-functionalized copper nanoparticles.Sodium is a vitally important electrolyte present in all body fluids and it plays a crucial role in maintaining normal body function, including nerve and muscle function. It is also referred to as natrium or Na+.Electrolytes are minerals that carry a charge and exist in your body fluids. Sodium along with other electrolytes helps cells to function normally and it helps to regulate the amount of fluid (water and electrolyte) balance in the body. It stimulates muscle contraction and maintains a stable acid-base balance in blood and tissue cells.Low blood sodium hyponatremia is occurring commonly in older adults, especially those who are hospitalized or living in long-term care facilities. Signs and symptoms of hyponatremia can include altered personality, lethargy and confusion. Severe hyponatremia can cause seizures, coma and even death.Blood sodium measurement is used to detect the cause and help monitor treatment in persons with dehydration, oedema, or with a variety of symptoms. The blood sodium concentration is abnormal in many diseases, particularly, if the patient has symptoms of illness involving the brain, lungs, liver, heart, kidney, thyroid, or adrenal glands.The most serious symptoms of high blood sodium hypernatremia result from brain dysfunction. Severe hypernatremia can lead to confusion, muscle twitching, seizures, coma, and death. Similarly, regular diagnosis of sodium concentration in excreted urine can help to detect the cardiovascular diseases and hypertension.Point of Care test (POCTs) are portable, rapid, and cost-effective analysis and diagnosis in modern healthcare. They are a radical departure from the conventional clinical laboratory techniques to self or bedside diagnostic methods, which can be operated without experienced technicians.The largest benefit of POCTs are that they can be done rapidly and be performed by clinical personnel who are not trained in clinical laboratory procedures. Rapid test results can provide a physician and other clinical personnel with answers that can quickly help determine a course of action or treatment for a patientUrine sodium concentrations are typically tested in patients who have abnormal blood sodium concentrations, to help determine whether an imbalance is due to taking in, or losing, too much sodium. Urine sodium is also used to see if a person with high blood pressure is eating too much salt. This test is often used in persons with abnormal kidney tests to help the doctor determine the cause of kidney disease, which can help guide treatment.However, ions like potassium ion (K+), Mg2+ and Zn2+ do interfere with the Na+ in the conventional test, which poses a major hurdle in sodium detection.A variety of methods are used for the determination of sodium present in urine such as ion-selective electrodes and ion chromatography which are very accurate and free of errors. However, these are expensive methods, the testing process takes a long time of about 24 hours, and the quantity of sample required is relatively large.In contrast, paper-based dipsticks are more convenient to use, affordable, and provide quick results.In view of this, various nanoparticle-based approaches are also being developed for the detection of sodium ion concentration in the body fluid. However, interfering ions are posing a major obstacles in the case of ion sensing. In the case of sodium ion detection, particularly, Ions like K+, Mg2+ and Zn2+ cause major interference, which shows indiscernible nature in nanoparticle-based colorimetric sensing.Extensive research activities are in progress on novel sensing technologies like lateral flow strips and microfluidic pads for early diagnosis of diseases. Among the newly emerging sensing technologies, colorimetric sensing is of paramount importance because it is an easy, economical and reliable method that is amenable to the visual detection.The presence of metal ions, proteins, amino acids and specific biomarkers can be detected using colorimetric sensing. Also, paper-based strips can be used, which are inexpensive, and they are easy to use in devices for patients for diagnostics and emergency applications.The colorimetric sensing technique involves changes in color that make it possible to detect analytes in an expeditious manner with the naked eye and without the use of any complicated instrument. This provides a simple yet powerful detection mechanism that is well-suited to the development of low-cost and low-power sensors.Generally, the sensing mechanism is based on the molecular interaction attractive or repulsive forces between molecules and between non-bonded atoms between the specific analytes and the nanoparticles surface that is decorated with suitable surfactants. Nanoparticles, as label-free systems, exhibit efficient chemical or biological sensing properties. The availability of the finest colloidal metal nanostructures with meticulously engineered surfaces makes the detection endowed with high selectivity and sensitivity.Metal nanostructures depending on their size and shape possess noteworthy attributes, including catalytic, optical, electrical, and chemical properties; hence they are excellent candidates as sensors for optical, and catalytic and various other functional applications. They possess unique structural and optical properties, including quantum size effects, Surface plasmon resonance (SPR), along with large surface to volume ratio, which makes them ideally suited for broad areas of material applications.Recently, metal nanoparticles are being used for biomedical applications, including biosensing, immunotherapeutics, drug delivery, regenerative medicine, bioimaging, and wound healing.Among metal nanoparticles, copper nanoparticles (Cu NPs) have emerged as promising candidates for biomedical applications, especially biosensing, owing to the Surface plasmon resonance (SPR) spectra occurring in the visible range and fluorescence properties with favorable quantum yield.Nanoparticles are easily prone to surface oxidation, because copper oxides are more stable in the atmosphere. So, in general, synthesis methods using efficient surface modification agents are more appealing to prevent the oxidation of Cu NPs. Surfactants or ligands like citric acid, glutathione and cysteine, are normally used for protecting the surface of metal nanoparticles, especially Cu NPs. These surface modified Cu NPs hold great potential for the fabrication of colorimetric and fluorescence-based sensor strips.In the present study (Scientific Reports, "Development of a paper printed colorimetric sensor based on Cu-Curcumin nanoparticles for evolving point-of-care clinical diagnosis of sodium."), the research team has synthesized Curcumin functionalized Cu nanoparticles (CuC) and examined their application in sodium metal ion detection.Schematic illustration of the formation of curcumin capped Cu NPs (CuC). (Image: Adapted from Scientific Reports, Springer Nature)Curcumin is the active component of turmeric with bright yellow color In the present investigation, the researchers have used curcumin to protect the Cu NPs from oxidation and agglomeration. They observed that the sensing system made up of CuC exhibits high levels of selectivity for sensing and quantifying Na+ ions.In this work, paper-based sodium sensor strips were fabricated, and it was found that visual detection of Na+ is possible in the physiological range using the same system. Using chemical reduction technique, the researchers synthesized nanoclusters of 39 nm-size consisting of highly stable, pure copper nanoparticles surface-functionalized with curcumin.TEM image of curcumin capped Cu NPs (CuC). Inset figure shows the curcumin cage and inner core. (Image: Adapted from Scientific Reports, Springer Nature)Each nanocluster of particles is encapsulated with a curcumin layer, which is clearly visible in TEM images. The researchers found that these curcumin functionalized Cu NPs (CuC) are highly selective to the colorimetric detection of Na+. The ions like K+, Mg2+ and Zn2+ did not interfere with the Na+ in this sensing technique.In this work, low-cost paper-based sensor strips are fabricated and calibrated for the sensing of sodium in the physiological range and shade cards were developed as a calorimetric guide for estimation of Na+, which makes them ideal point of care diagnostic platform.The authors demonstrate that the proposed CuC paper strip can be used for detecting Na+ concentration within the whole physiological range in both blood serum and urine.By Yashwant Mahajan, Associate Editor, Nanowerk

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Nanotechnology-enabled low-cost, point-of-care, self-test of sodium in the comfort of your home - Nanowerk

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Fact Check: Governments are using nanotechnology to create mosquitoes and spread disease. | The Paradise News – The Paradise News

Genetically modified mosquitoes have been created to prevent diseases like dengue, chikungunya, and malaria; not to spread or develop them.

A claim on social media states that governments are using nanotechnology to create mosquitoes and spread disease. The claim is a part of a broader conspiracy theory, which states that viruses such as Zika have been created through the genetic modification (GM) of mosquitoes and that GM mosquitoes have been created for the purposes of surveillance and population control.

According to the Centers for Disease Control and Prevention (CDC), genetically modified mosquitoes are produced to control Aedes Aegypti mosquitoes known more commonly as yellow fever mosquitoes which spread viruses including dengue, Zika, and chikungunya. GM mosquitoes created in a lab have two types of genes: one that keeps the female mosquito offspring from surviving to adulthood and another that makes them identifiable in the dark. The report states that these modified mosquitoes do not stop an ongoing disease outbreak; however, they are meant to help prevent disease outbreaks. The CDC adds that the GM mosquitoes do not pose a risk to people, animals, or the environment.

According to the National Library of Medicine, arboviruses, which cause diseases like dengue, and chikungunya, are challenging to control due to various factors, such as the lack of effective vaccines and antiviral drugs. Some of these, including the Aedes species, are resistant to insecticides. Therefore, it is necessary to resort to approaches that can detect and control the spread of arboviruses. In this regard, the importance of nanobiotechnology has been gradually realized as an emerging technology of the future due to exceptional new benefits, NCBI adds.

According to the World Health Organization, the number of reported dengue cases has increased tenfold in the last twenty years, from 505,430 cases in 2000 to over 2.4 million in 2010 and 5.2 million in 2019. Reported deaths between 2000 and 2015 increased from 960 to 4032, mainly affecting the younger age group.

The main reasoning and logic behind creating genetically modified mosquitoes is to control diseases such as dengue and malaria, and prevent deaths due to these diseases. Therefore, the claim that GM mosquitoes are designed to create disease is baseless.

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Fact Check: Governments are using nanotechnology to create mosquitoes and spread disease. | The Paradise News - The Paradise News

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Emerging technologies – The News International

The rapid emergence of new technologies is transforming the world around us in almost magical ways. They range from strange new materials that make objects invisible to the naked eye when they are coated by those materials, to new species of plants and animals that can be created in the lab through a process of gene editing.

Devices have been developed that restore partial eyesight to the blind through images that can be transferred through the nervous system of the tongue to the brain. Anti-ageing compounds are being developed that slow down the process of ageing. It is thought that children being born today will have average lives of 120 years plus. Graphene has been developed which is 200 times stronger than steel and it is finding many applications.

Artificial intelligence is developing at a very rapid pace and finding its way in a myriad applications, ranging from city traffic management to drug discovery, from stock exchange appraisals to unravelling health and environmental issues. There is particular interest in the applications of artificial intelligence in areas like neural networking.

Some of these new technologies are finding their way into modern warfare. Swarms of intelligent drones that can interact together and attack enemy tanks in a highly organized and orchestrated manner are changing the dynamics of war and making the tank and the foot soldier progressively redundant. The Turkish Bayraktar TB2 drone, a combat drone with a wingspan of 12 meters and an armament of four laser-guided bombs, along with others supplied from the West have caused havoc to Russian tanks and other heavy ground weaponry. Small portable switchblade drones are also being successfully employed in Ukraine. These are comfortably transported in a tube from which they can be launched directly. Once launched, their wings snap out and the propulsion systems are activated.

Another rapidly emerging field is that of nanotechnology. Nanotechnology emerged serendipitously when it was discovered that remarkable changes of properties in materials occur when their sizes are reduced to between one nanometer (nm) and 100 nm. A nanometer is a billionth of a meter about the same proportion to a meter, as a marble is to the earth. For instance, if we pulverize gold particles and bring them to the nano-meter size, then the colour of gold changes to blue-green, red or purple, depending on the particle size

Nanotechnology applications range across all science fields such as biomedical, chemical, mechanics, electronics, computer sciences and material science. Nanoscale sensors and devices are providing cost-effective continuous monitoring of the structural integrity and performance of bridges, tunnels etc. They are also being employed to support an enhanced transportation infrastructure to help drivers maintain lane position, avoid collisions, adjust travel routes to avoid congestion.

Nanotechnology is also finding a multitude of applications in water purification, medicine, cosmetics, electronics, new materials and many other fields. In the field of nano-electronics alone, the market size is estimated to be around $4 trillion and is growing rapidly. Similarly bullet-proof jackets have been developed based on bullet proof paper made from nano-cellulose these jackets are light, absorbent and bullet proof! The global nanotechnology market size is estimated to be at about $1.80 billion and it is projected to reach $33.63 billion by 2030, registering a CAGR of 36.4 percent from 2021 to 2030.

Another exciting area of rapid development is that of energy. New and more efficient solar cells are being developed. Special paints have been developed with built-in solar cells so that they can produce electricity when sunlight falls on them. Advances on new more efficient batteries to drive electric cars are another area of hot research.

These and other amazing technologies are rapidly transforming our world, and the businesses that can produce and make use of them are flourishing. It is interesting that computer systems based on biological models was the fastest-growing technology among the new and emerging technologies with 67 percent growth in terms of new patents filed between 2016 and 2020. Google, Microsoft and Intel are leaders in the area. Major increases are also being seen in the new patents filed in the fields of machine learning, quantum computing, autonomous technology and 3D printing.

Excellent beginnings in some of these fields have been made in Pakistan with the establishment of the Pak Austrian University of Applied Science and Engineering (Pak Austrian Fachhochschule) in Haripur, Hazara and a similar university is now under construction in Sialkot. Several centers for Artificial Intelligence have been established including the excellent National Center for Artificial Intelligence in NUST, Islamabad, as well as in NED Engineering University, UET Lahore and other universities.

The Sino-Pak Center for Artificial Intelligence has also begun operations in the Pak Austrian University in Haripur in collaboration with top universities in China and Austria. Pakistans first National Center for Nanotechnology has been established at the International Center for Chemical and Biological Sciences at Karachi University.

The Pak Austrian University of Applied Science and Engineering will be particularly focusing on the training of Pakistani students in such new and emerging technologies. It is headed by an eminent Pakistani scientist Prof Mohammed Mujahid, and has Prof Nasser Ali Khan leading the development effort as project director. It happens to be the first university in the world with two key features. First, it has two academic sections, a Fachhochschule section providing high level technical training at the BSc and MSc levels, and a postgraduate PhD postdoctoral level research university section. Second, each department of the is godfathered by a reputable Austrian or Chinese University that will be closely involved in quality assurance, faculty development, technicians training and ensuring the quality of examinations. A major priority of this university is on high-technology product development and so its centre piece is its technology park where vigorous development of various commercial products are under way in close collaboration with industry. Another similar university is under development in Sialkot.

The writer is chairman PM National Task Force on Science and Technology, former minister, and former founding chairman of the HEC. He can be reached at: ibne_sina@hotmail.com

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Emerging technologies - The News International

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Quantum Dot Technology Market Analysis, Research Study With Ebioscience Inc., Evident Technologies, Altair Nanotechnology Inc. The New York Irish…

California (United States) The Quantum Dot Technology Market Research Report is a professional asset that provides dynamic and statistical insights into regional and global markets. It includes a comprehensive study of the current scenario to safeguard the trends and prospects of the market. Quantum Dot Technology Research reports also track future technologies and developments. Thorough information on new products, and regional and market investments is provided in the report. This Quantum Dot Technology research report also scrutinizes all the elements businesses need to get unbiased data to help them understand the threats and challenges ahead of their business. The Service industry report further includes market shortcomings, stability, growth drivers, restraining factors, and opportunities over the forecast period.

Quantum Dot technology is widely being used in the optical data process and LASER systems as a light sources and amplification respectively.

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Global Quantum Dot Technology Market Segmentation:

Market Segmentation: By Type

DisplayLightingOthers

Market Segmentation: By Application

Consumer ElectronicsAerospace & DefenseHealthcareOthers

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Quantum Dot Technology Market Analysis, Research Study With Ebioscience Inc., Evident Technologies, Altair Nanotechnology Inc. The New York Irish...

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Agricultural Nanotechnology Market Growth Projections, Demand and Opportunity Assessment By 2028 The New York Irish Emgirant – The New York Irish…

Agricultural Nanotechnology Market research report guides the business in every sphere of trade to take the unmatched decisions, to tackle the toughest business questions and diminish the risk of failure. The report endows with the estimations on the market status, growth rate, future trends, market drivers, opportunities, challenges, entry barriers, risks, sales channels, and distributors. To implement this market research study, competent and advanced tools and techniques viz SWOT analysis and Porters Five Forces Analysis have been employed. Because businesses can accomplish great benefits with the different segments covered in the market research report, every bit of market that can be included here is touched vigilantly.

In the credible Agricultural Nanotechnology market report, industry trends have been described on the macro level which makes it easy to outline market landscape and probable future issues. The report analyses and estimates general market drivers in the form of consumer demand, government policy and demand which are related to consumer buying pattern, market growth and development. This market research report provides with a thorough analysis of market and numerous related factors that range from market drivers, market restraints, market segmentation, opportunities, challenges, and market revenues to competitive analysis. A worldwide Agricultural Nanotechnology report is also very beneficial when launching a new product or intensifying the business regionally or globally.

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Market Overview

Global agricultural nanotechnology market is expected to be growing at a growth rate of 11.7% in the forecast period of 2021 to 2028 and expected to reach USD 256 billion in 2020 to USD 620.3 billion by 2028.

Nanotechnology in agriculture is the application of minimal tools such as sensors, which can be used for agricultural development. Nanotechnology is a new revolution in industries and has the potential to bring about drastic changes in the agricultural industry. Development of new nanotech-based tools and equipment help increase efficiency and overcome challenges faced by the agricultural industry.

The research report offers in-depth insights about Agricultural Nanotechnology market status, market share, growth rate, future trends, market drivers, opportunities and challenges, risks and entry barriers, sales channels, and distributors and analysed well with the Porters Five Forces analysis. This market survey report takes into consideration several industry research, customer insights, market sizing & forecast, competitive analysis, market entry strategy, pricing trends, sustainability trends, innovation trends, technology evolution, and distribution channel assessment. An all-inclusive market document encompasses the top players along with their share by volume in key regions such as APAC, EMEA, and Americas and the challenges faced by them.

Competitive Analysis: Global Agricultural Nanotechnology market

Nanosys Inc, LYC North America, ASML, Zyvex, Oxford Instruments, Nanoco Group plc, ThalesNano Inc., eSpin Technologies, CHEMAT TECHNOLOGY INC., Integran Technologies Starpharma Holdings Limited, and Hyperion Catalysis International, other domestic

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Global Agricultural Nanotechnology Market Scope and Market Size

Global Agricultural Nanotechnology Market, By Product Type (Crop protection, Soil improvement, Water Purification, Diagnostic, Plant Breeding, Nanoparticles Production), Application (Nanoscale Carriers, Nanolignocellulosic Materials, Clay Nanotubes, Biosensors, Others), End User (Farmers, R&DInstitutes, Government Organization, Others), Country (U.S., Canada, Mexico, Germany, Poland, Ireland, Italy, U.K., France, Spain, Netherlands, Belgium, Switzerland, Turkey, Russia, Rest of Europe, Japan, China, India, South Korea, New Zealand, Vietnam, Australia, Singapore, Malaysia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific, Brazil, Argentina, Chile, Rest of South America, UAE, Saudi Arabia, Egypt, Kuwait, South Africa, Rest of Middle East and Africa) Industry Trends and Forecast to 2028.

The Report Includes

The analyzing tools like SWOT analysis and Porters Five Forces tool are utilized to get a clear picture of the Agricultural Nanotechnology market.

It develops and modifies business strategies by employing the growth analysis of the changing competitive dynamics of the industry.

The research methods and tools used to analyze the studies are primary and secondary research.

It encourages the global market decision by an in-depth 8-year forecast along with predictions of market size.

Futuristic outlook on factors driving and restraining the growth of the market.

Comprehensive analysis of the key product segments and their growth estimation for easy understanding.

Provides a competitive edge to the companies operating in the Agricultural Nanotechnology market trends.

Strategic recommendations to the established companies as well as new entrants in the industry.

In-depth analysis of Agricultural Nanotechnology market segments and complete insights of the market to assist in formulating investment strategies.

Key questions answered in the report:

What is the growth potential of the Agricultural Nanotechnology Market?

Which most crucial trends in the various segments will aid in deciphering and persuading the Agricultural Nanotechnology market?

Which regional market will emerge as a pioneer in the years to come?

Which application segment will experience strong growth?

What growth opportunities might arise in the Agricultural Nanotechnology industry in the years to come?

What are the most significant challenges that the Agricultural Nanotechnology Market could face in the future?

Who are the leading companies in the Agricultural Nanotechnology Market?

What are the important areas and countries involved in market growth, are determined by understanding the potential and progress of market?

What growth strategies are the players considering to stay in the Agricultural Nanotechnology Market?

What are various segments of the Agricultural Nanotechnology market, as well as the markets dynamics?

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Agricultural Nanotechnology Market Growth Projections, Demand and Opportunity Assessment By 2028 The New York Irish Emgirant - The New York Irish...

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Nanotechnology in Medical Devices Market 2022: Impact of Covid-19 on the Global Economy, Penetration, and Forecast of Industry Demand by 2028: Stryker…

Global Nanotechnology in Medical Devices MarketResearch Report provides key analysis on the market status of the Nanotechnology in Medical Devices with the best facts and figures, meaning, definition, SWOT analysis, expert opinions, and the latest developments across the globe. The report also calculates the market size, Sales, Price, Revenue, Gross Margin, Market Share, cost structure, and growth rate. The report considers the revenue generated from the sales of This Report and technologies by various application segments and Browse Market data Tables.

The Nanotechnology in Medical Devices Market report covers the different market scenarios that have a direct impact on the growth of the market. The Nanotechnology in Medical Devices report study includes information on market factors such as the market dynamics, including drivers, restraints, challenges, threats, potential growth opportunities, market trends, development patterns, financial information, latest technologies, innovations, leading competitors, and regional analysis of the market.

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Following Key Players are Mentioned in this Document:

Stryker Corporation (U.S.) 3M Company (U.S.) St. Jude Medical Inc. (U.S.) Affymetrix Inc. (U.S.) PerkinElmer Inc. (U.S.) Starkey Hearing Technologies (U.S.) Smith & Nephew plc (U.K.). Dentsply International Mitsui Chemicals Inc. AAP Implantate AG,

Analysis of Cardan ShaftMarket by Type

Active Implantable Medical Devices Biochip Portable Material,

Analysis of Cardan ShaftMarket by Application

Treatment Using Diagnostic Using Research Using,

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Regional Analysis for Nanotechnology in Medical Devices Market:

North America (U.S., Canada)Europe (U.K., Italy, Germany, France, Rest of EU)Asia-Pacific (India, Japan, China, South Korea, Australia, Rest of APAC)Latin America (Chile, Brazil, Argentina, Rest of Latin America)Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of MEA)

(*NOTE: To get customization to your liking you can ADD / REMOVE Key Players, Regions, and any other Segments as you need.)

How Covid 19 Affected the Nanotechnology in Medical Devices Market

Since the COVID-19 virus outbreak in December 2019, the disease has spread to almost every country around the globe with the World Health Organization declaring it a public health emergency. The global impacts of the coronavirus disease 2019 (COVID-19) are already starting to be felt, and will significantly affect the Impact Nanotechnology in Medical Devices market in 2020. The outbreak of COVID-19 has brought effects on many aspects, like flight cancellations, travel bans, and quarantines, restaurants closed, all indoor/outdoor events restricted, over forty countries state of emergency declared, massive slowing of the supply chain, stock market volatility, falling business confidence, growing panic among the population, and uncertainty about future.

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In this segment, we will give you the impact of COVID-19, how it affected the Nanotechnology in Medical Devices market, and how it will change the industrys future depending on the current government, private, and public situations. Our expert analysts keep an open eye on every situation that may change the flow of the industry which will help you make the best possible decision for your enterprise.

The objective of the study is to define the Nanotechnology in Medical Devices market sizes of different segments and countries in previous years and to forecast the values for the next five years. The report is designed to incorporate both qualified, qualitative and quantitative aspects of the industry with respect to each of the regions and countries involved in the study. Furthermore, the report also caters the detailed information about crucial aspects such as drivers and restraining factors that will define the future growth of the Nanotechnology in Medical Devices market.

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Nanotechnology in Medical Devices Market 2022: Impact of Covid-19 on the Global Economy, Penetration, and Forecast of Industry Demand by 2028: Stryker...

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