Category Archives: Nano Medicine

2012 Deakin University 3 Minute Thesis Finalist - Jarrad Altimari
A 3MT presentation on a Nano medicine Approach to Prostate Cancer.From:deakinresearchViews:116 0ratingsTime:02:48More inEducation

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2012 Deakin University 3 Minute Thesis Finalist - Jarrad Altimari - Video

Deakin University - Practical Science - Nano medicine
http://www.deakin.edu.au An interview with Deakin University research fellow Dr Rupinder Kanwa as she discusses Deakin Uni #39;s groundbreaking Nano Medicine research Another one of many great reasons to come to Deakin University Open DayFrom:deakinuniversityViews:44 0ratingsTime:01:14More inEducation

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Deakin University - Practical Science - Nano medicine - Video

Kochi, Oct 15 (UNI)

Amrita Centre for Nanosciences and Molecular Medicine, part of the Amrita Institute of Medical Sciences and Research Centre has claimed to have discovered a potential cure for drug resistant leukemia.

Chronic Myeloid Leukemia (CML) responds well to a drug named 'Imatinib', however, when drug resistance sets in, which is in about 20-25 per cent of the cases, the patients has little chance of survival, a press release said here today.

Drug resistance was due to certain point mutations in the leukemia cells as a result of which the cells find an alternative pathway for survival, preventing the drug from killing the cancer cells, it said.

The Centre has developed a nanomedicine which had shown significant ability to kill the drug reststant cancer cells.

The nanomedicine was developed over the past three years and has shown success in in-vitro (or cell line based) studies, it added.

The Centre was now conducting animal trials or pre-clinical studies of the drug, it said, adding that it is expected that if pre-clinical trials are successful the new nano medicine can be submitted for clinical trial after approval from the government.

This was the first such discovery in the world of nanomedicine that effectively solves the problem of severe drug resistance in blood cancers.

The senior scientists involved in the research and development was Dr Manzoor Koyakutty, Professor and Dr Shantikumar Nair, Centre Director and Dean of Research.

Clinicians from the hospital who are involved in the research are Dr Pavithran, Dr Neeraj and Dr Prabhu. The PhD student who has worked on this as part of her PhD thesis is Archana Ratnakumari, it added.

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New hope for leukemia patients

SKOKIE, IL--(Marketwire - Oct 11, 2012) - NanoGuardian, a division of NanoInk, Inc. that delivers on-dose brand protection solutions to the pharmaceutical industry to fight counterfeiting and illegal diversion, announced today that it will give a poster presentation at the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exhibition, which is being held on October 14 - 18, at McCormick Place in Chicago. The abstract, "Can Nanofabrication be used to Combat Counterfeit Medicines by Applying On-dose Authentication Features without Disrupting the Integrity of the Medicine?" will be presented on Monday, October 15, from 1:30 to 4:30 p.m. in Hall F by Bjoern Rosner, director of research and development, brand protection for NanoGuardian.

"Counterfeit medicines have become such a problem that pharmaceutical manufacturers are evaluating how to best ensure the integrity of their medicines for patients early in the drug development process," said Dean Hart, chief commercial officer of NanoGuardian. "The AAPS poster presentation will demonstrate that NanoGuardian's NanoEncryption technology can be used to incorporate highly sophisticated nanoscale, authentication, and tracing features directly on film-coated tablets, gelatin capsules, and vial caps without affecting the dissolution or stability of the medication -- important considerations in the development and commercialization of a new medication."

NanoGuardian's NanoEncryption technology is the only on-dose, multi-layered, brand protection solution that enables pharmaceutical manufacturers to authenticate and trace every single dose, from plant to patient. NanoGuardian's Closed-Loop Protection Program combines the on-dose authentication and tracing benefits of NanoEncryption technology with a proactive supply chain auditing program to identify counterfeit or illegally diverted pharmaceuticals entering the global supply chain as early as possible.

NanoGuardian fights both counterfeiting and illegal diversion with a single technology that can be used to protect capsules, tablets, vial caps, and single-use syringes providing a layered security of overt, covert, and forensic features. The overt and covert security features allow dose-level authentication at any point in the supply chain, while the forensic and nano-scale NanoCodes provide comprehensive tracing information on each and every dose. NanoGuardian's technology provides a strong benefit over other on-dose technologies given that NanoGuardian's security features are implemented with no additional material or chemicals being added to the medication.

As evidence of the rapidly growing problem of counterfeit pharmaceuticals, a recent report from the U.S. Customs and Border Protection and the U.S. Immigration and Customs Enforcement noted that the domestic value of counterfeit pharmaceutical seizures in fiscal year 2011 rose by more than $11 million, an increase of almost 200 percent. The implications for victims of counterfeit drugs are extremely serious, often resulting in unexpected side effects, severe allergic reactions and even death.

AAPS provides a dynamic international forum for the exchange of knowledge among scientists to enhance their contributions to health. It offers timely scientific programs, ongoing education, opportunities for networking, and professional development. More information is available at: http://www.aaps.org.

About NanoGuardian NanoGuardian, a division of NanoInk, Inc., focuses exclusively on delivering brand protection solutions to fight illegal diversion and counterfeiting. Anchored by NanoInk's novel NanoEncryption technology, NanoGuardian enables manufacturers to authenticate and trace the integrity of their products across the supply chain. More information about NanoGuardian is available at http://www.nanoguardian.net.

NanoInk, NanoGuardian, NanoEncryption and the NanoGuardian logo are trademarks or registered trademarks of NanoInk, Inc.

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NanoGuardian's On-Dose NanoEncryption Brand Protection Technology to Be Presented at AAPS Annual Meeting

Printing off a kidney or another human organ may sound like something out of a science fiction novel, but with the advancements in 3D printing technology, the idea may not be so far-fetched.

BioprintingWhile 3D printing has been successfully used in the health care sector to make prosthetic limbs, custom hearing aids and dental fixtures, the technology is now being used to create more complex structures - particularly human tissue.

Organovo (onvo), a San Diego-based company that focuses on regenerative medicine, is one company using 3D printers, called bioprinters, to print functional human tissue for medical research and regenerative therapies.

"This is disruptive technology," said Mike Renard, Organovo's vice president of commercial operations. "It's always interesting and fun, but never easy."

(More From CNBC: 15 Surprising Global Technology Cities)

Traditional 3D printing, also known as additive manufacturing, is a process of making three dimensional solid objects from a digital model. 3D printing is achieved using additive processes, in which an object is created by laying down successive layers of material such as plastic, ceramics, glass or metal to print an object. Companies including Boeing (ba), General Electric (ge) and Honeywell (hon) use this type of 3D printing to manufacture parts.

Bioprinters, though, use a "bio-ink" made of living cell mixtures to form human tissue. Basically, the bio-ink is used to build a 3D structure of cells, layer by layer, to form tissue.

Eventually, medical researchers hope to be able to use the printed tissue to make organs for organ replacement.

However, growing functional organs is still at least 10 years away, said Shaochen Chen, a professor of nano-engineering at the University of California, San Diego, who uses bioprinting in researching regenerative medicine.

But even though developing functional organs may still be a decade off, medical researchers and others are using bioprinting technology to make advancements in other ways.

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How 3D Printers Are Reshaping Medicine

Eqalix Inc., an emerging regenerative medicine company, announces its Scientific Advisory Board (SAB). This SAB gives Eqalix a depth and breadth of experience necessary to take it to the next level.

Reston, VA (PRWEB) October 09, 2012

"We are very pleased to bring together these key thought leaders to establish the Eqalix Scientific Advisory Board," stated Joseph P. Connell, Eqalix CEO and Chairman of the Board. "I have worked with Drs. Gold and Goldman for years and have always admired their abilities. Dr Lelkes technologies will make a profound impact upon aesthetic dermatology, wound healing and regenerating blood vessels, nerve endings and damaged organs with the guidance of this distinguished panel. It is not clich in any manner when I say that we are thrilled to work with this team. We look to their guidance, industry knowledge and network to help deliver these therapies into clinic and prospective patients as soon as possible, as I am confident our technologies will make a difference, said Connell.

The members of the Eqalix Scientific Advisory Board are:

Peter I. Lelkes, PhD: Chief Scientific Advisor; Dr. Lelkes is the Laura H. Carnell Professor and Founding Chair of the Department of Bioengineering in the College of Engineering at Temple University and the Inaugural Director of the Institute for Regenerative Medicine and Engineering (TIME) at Temple Universitys School of Medicine. While at Drexel, Prof. Lelkes directed an interdisciplinary program in tissue engineering and regenerative medicine, focusing on nanotechnology-based biomaterials and soft tissue engineering, employing developmental biological principles to enhance the tissue-specific differentiation of embryonic and adult stem cells. Dr. Lelkes has organized several Keystone conferences and published more than 160 peer-reviewed papers and 45 book chapters and made more than 400 presentations nationally and internationally.

Dr. Lelkes basic and translational research has been support by federal (NIH, NSF, NASA, DOE) and state funding agencies, (NTI and Dept. of Commerce, Tobacco Settlement Funds) and private Foundations, including the Coulter Foundation. Most recently, Dr. Lelkes has been named Director of the Surgical Engineering Enterprise, one of the major initiatives of the strategic plan of Drexel Universitys College of Medicine. In addition, Dr. Lelkes has been the team leader for tissue engineering at the Nanotechnology Institute of Southeastern Pennsylvania (NTI) and is the Co-Director of PATRIC, the Pennsylvania Advanced Textile Research and Innovation Center, focusing on BioNanoTextiles and Stem Cell Biology.

Dr Lelkes stated, "I am delighted and excited to partner with Eqalix to translate our inventions from the bench to the bedside in a timely fashion.

Mitchel P. Goldman, MD, Scientific Advisor, Founder and Medical Director of Goldman Butterwick Fitzpatrick, Groff & Fabi, Cosmetic Laser Dermatology. A graduate of Boston University, Summa Cum Laude, and the Stanford University Medical School, Dr. Goldman is a Volunteer Clinical Professor in Medicine/Dermatology at the University of California, San Diego. Dr Goldman is Board Certified by both the American Board of Dermatology and the American Board of Cosmetic Surgery.

He is a fellow of the American Academy of Dermatology, American Society for Dermatologic Surgery, American Society for Laser Medicine and Surgery, American Academy of Cosmetic Surgery and the American Society of Liposuction Surgery. He is former President of the American College of Phlebology and President-Elect of the American Society for Dermatologic Surgery. He presently serves on the Board of Trustees for the American Academy of Cosmetic Surgery. He also has authored and/or co-authored 21 Textbooks on Dermatology, Sclerotherapy, Ambulatory Phlebectomy, Cutaneous Laser Surgery, Cellulite and Dermatologic Surgery as well as over 300 peer-reviewed publications and textbook chapters.

Dr Goldman added: I am very interested and excited to work with the Eqalix team to make these technologies a success. I believe that my background lends well to truly shaping the successful commercialization of these products for my patients to improve outcomes.

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Regenerative Medicine Biotech Company, Eqalix, Names Scientific Advisory Board