Category Archives: Nano Medicine

Although it's possible to remove warts by freezing them with liquid nitrogen, they often grow back, requiring multiple treatments. New research, however, suggests that ultra-short electrical pulses could be much more effective at eliminating warts and other skin lesions.

Combining the findings from multiple previous studies, scientists from California-based Pulse Biosciences recently evaluated a type of therapy known as nano-pulse stimulation (NPS). In a nutshell, it involves subjecting lesions to a series of electrical pulses, each one lasting just one nanosecond (one one-billionth of a second).

The electrical pulses create nanometer-wide pores within the cells of the lesions, through which sodium, potassium and calcium ions can enter. This in turn disrupts the flow of those same types of ions in and out of the cells, ultimately resulting in cell death.

In one test of the procedure, 174 seborrheic keratosis lesions each received a single treatment that lasted less than one minute. A few weeks later, over 82 percent of those lesions crusted over and peeled off. Because the collagen and fibrin that make up healthy skin are not affected by NPS, however, the skin that was revealed beneath the lesion sites was not scarred.

In another trial, a single NPS treatment was found to clear 99 percent of facial sebaceous gland hyperplasia lesions within 60 days. Eighteen of the lesions required a second treatment, which was most often due to the target being missed on the initial treatment.

And when NPS was used to treat 23 warts that were resistant to liquid nitrogen treatment, "a majority" of those warts died and fell off within 60 days.

"NPS technology has been shown to be very effective in the clearance of many types of cellular skin lesions while sparing the noncellular components of the dermis," states the lead scientist, Dr. Richard Nuccitelli. "The proper energies can provide scarless lesion elimination with short treatment times and very high efficacy."

A paper on the research was recently published in the journal Bioelectricity.

Source: Mary Ann Liebert, Inc.

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Tiny zaps used to kill stubborn warts - New Atlas

The report titled Global Nano Chemotherapy Market Size, Status and Forecast 2019-2025 provide (6 Year Forecast 2019-2025)enhanced on worldwide competition by topmost prime companies (Amgen, Celgene, MagForce AG, Nanotherapeutics, Spectrum Pharmaceuticals, Ablynx, AMAG, CytImmune, Delpor, Nanospectra, Merrimack, Tarveda) which providing information such asCompany Profiles, Capacity, Gross, Gross Margin, Product Picture and Specification, Production, Price, Cost, Revenueand contact information. This Nano Chemotherapy market report crucial insights that facilitate theMarket Trends, Drivers, Market Dynamics, Overview, Scope, Definitions, Classifications, Opportunities, Competitive Landscape. The report provides key statistics on the market status of the Nano Chemotherapy market manufacturers and is a valuable source of guidance and direction for companies and individuals interested in the industry.

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Scope of Nano Chemotherapy Market:The report affords a basic outline of the Nano Chemotherapy Market report contains definitions, competitive landscape evaluation, segmentations, applications, key providers, market drivers and challenges. The Nano Chemotherapy Research report presents a complete assessment of the Market and contains a future trend, current growth factors, attentive opinions, facts, and industry validated market data.

On the basis of product, this report displays the sales volume, revenue (Million USD), product price, market share and growth rate of each type, primarily split into-

Medicine Therapy Physical Therapy Other

On the basis on the end users/applications, this report focuses on the status and outlook for major applications/end users, sales volume, market share and growth rate of Nano Chemotherapy market for each application, including-

Hospitals Clinics Other

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Nano Chemotherapy Market: Regional Analysis Includes:

The Nano Chemotherapy Market Report Can Answer The Following Questions:

What is the (North America, South America, Europe, Africa, Middle East, Asia, China, Japan) production, production value, consumption, consumption value, import and export of Nano Chemotherapy market?

Who are the key manufacturers of Nano Chemotherapy market? How are their operating situation (capacity, production, price, cost, gross and revenue)?

What are the upstream raw materials and manufacturing equipment of Nano Chemotherapy? What is the manufacturing process of Nano Chemotherapy?

Economic impact on Nano Chemotherapy industry and development trend of Nano Chemotherapy industry.

What will the Nano Chemotherapy market size and the growth rate be in 2025?

What are the key market trends impacting the growth of the Nano Chemotherapy market?

What are the Nano Chemotherapy market challenges to market growth?

What are the Nano Chemotherapy market opportunities and threats faced by the vendors in the Nano Chemotherapy market? Etc.

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Nano Chemotherapy Market: Global Segments, Top Key Players, Size And Recent Trends By Forecast To 2025 - Market Research Sheets

Latest release from SMI with title Nanomedicine Market Research Report 2019-2026 (by Product Type, End-User / Application and Regions / Countries) provides an in-depth assessment of the Nanomedicine including key market trends, upcoming technologies, industry drivers, challenges, regulatory policies, key players company profiles and strategies. Global Nanomedicine Market study with 100+ market data Tables, Pie Chat, Graphs & Figures is now released BY SMI. The report presents a complete assessment of the Market covering future trends, current growth factors, attentive opinions, facts, and industry-validated market data forecast until 2026.

Global Nanomedicine Market Segmentations

The segmentation chapter allows readers to understand aspects of the Global Nanomedicine Market such as products/services, available technologies, and applications. These chapters are written in a way that describes years of development and the process that will take place in the next few years. The research report also provides insightful information on new trends that are likely to define the progress of these segments over the next few years.

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Global Nanomedicine Market and Competitive Analysis

Know your current market situation! Not only an important element for new products but also for current products given the ever-changing market dynamics. The study allows marketers to stay in touch with current consumer trends and segments where they can face a rapid market share drop. Discover who you really compete against in the marketplace, with Market Share Analysis know market position, % market Share and Segmented Revenue of Nanomedicine Market

Segmentation and Targeting

Essential demographic, geographic, psychographic and behavioral information about business segments in the Nanomedicine market is targeted to aid in determining the features company should encompass in order to fit into the business requirements. For the Consumer-based market the study is also classified with Market Maker information in order to better understand who the clients are, their buying behavior and patterns.

*** For the global version, a list of below countries by region can be added as part of customization at minimum cost.North America (United States, Canada & Mexico)Asia-Pacific (Japan, China, India, Australia, etc)Europe (Germany, UK, France, etc)Central & South America (Brazil, Argentina, etc)Middle East & Africa (United Arab Emirates, Saudi Arabia, South Africa, etc)

Nanomedicine Product/Service Development

Knowing how the product/services fit the needs of clients and what changes would require to make the product more attractive is the need of an hour. Useful approaches to focus group by utilizing User Testing and User Experience Research. Demand-side analysis always helps to correlate consumer preferences with innovation.

Marketing Communication and Sales Channel

Understanding marketing effectiveness on a continual basis help determine the potential of advertising and marketing communications and allow us to use best practices to utilize an untapped audience. In order to make marketers make effective strategies and identify why the target market is not giving attention, we ensure the Study is Segmented with appropriate marketing & sales channels to identify potential market size by Revenue and Volume* (if Applicable).

Pricing and Forecast

Pricing/subscription always plays an important role in buying decisions; so we have analyzed pricing to determine how customers or businesses evaluate it not just in relation to other product offerings by competitors but also with immediate substitute products. In addition to future sales Separate Chapters on Cost Analysis, Labor*, production* and Capacity are Covered.

How geography and sales fit together

This study is helpful to all operators who want to identify the exact size of their target audience at a specific geographic location. Nanomedicine Market allows entrepreneurs to determine local markets for business expansion. This study answers the questions below:

1. Where do the requirements come from?2. Where do non-potential customers reside?3. What is the buying behavior of customers in a specific region?4. What is the spending power of the customers in a particular region?

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Having our reviews and subscribing our report will help you solve the subsequent issues:

*Uncertainty about the future: Our research and insights help our customers predict the upcoming revenue pockets and growth areas. This will guide customers to invest their resources.

*Understanding market sentiments: It is very important to have a fair understanding of market sentiment for your strategy. Our insights will help you see every single eye on market sentiment. We maintain this analysis by working with key opinion leaders on the value chain of each industry we track.

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Furthermore, the years considered for the study are as follows:

Historical year 2013-2018Base year 2018Forecast period** 2019 to 2026 [** unless otherwise stated]

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Nanomedicine Market to witness Huge Growth with Projected up to 2026 - Market Reports Observer

A typical father and son project might mean restoring a classic car or completing a home renovation, but this Christchurch pair have set their sights a little higher. LEE KENNY reports.

Phil and Anthony Butlerhave utilised cutting-edge technologyused in the hunt for the Higgs Boson to invent the world's first 3-D colour X-ray.

Phil is a professor at University of Canterbury and a Fellow of New Zealand Institute of Physics, while Anthony is a clinical radiologist and a professor at University of Otago.

Together they have created the MARS scanner, which will one day replace many of the functions of the X-ray, positron emission tomography (PET) scans and magnetic resonance imaging (MRI).

ALDEN WILLIAMS/STUFF

Phil and Anthony Butler work on an arm scanner at MARS' Christchurch laboratory.

READ MORE:* What will be the biggest scientific breakthrough of 2020?* Defence Force medic's bleeding edge invention wins Manawat's Innovate 2019* Where did the curiosity go?

The non-invasive technique will enable doctors to see colour images from inside the body, allowing them to make a more accurate diagnosis when treating everything from a broken bone to heart disease.

Phil, 72, first thought about the concept while he was atCERN (European Organization for Nuclear Research) in 2002.

Scientists working on the Large Hadron Collider used high-tech Medipix detectors to track particles and it was theorisedthey could also be used to detect X-ray photons.

Anthony joined CERN in 2005 and it was while the Butlerswere on a family holiday in Croatia that they decided to put the theory to the test.

Supplied

A 3-D image of Phil Butler's wrist taken by the MARS scanner in 2018.

They founded MARS Bioimaging in 2007 and today their 50-strong team consists of physicists, radiologists, mathematicians, biologists, engineers and computer scientists.

The company is part owned by University of Canterbury where it is based and has close ties to Otago Medical School.

Anthony, 44, explains the machine works by shining X-rays through the body and measuring the tissue composition before a computer reconstructs the information into a high-resolution 3-D colour image.

"The underlying process is often called spectral photon counting we measure the X-ray beam one photon at a time, which means we need to have very fast electronics to do this."

He says they have been looking at several medical applications for the scanners, across a range of clinical disciplines.

ALDEN WILLIAMS/STUFF

Professor Phil Butler is the chief executive of MARS Bioimaging but still takes a hands-on role.

"We've been working with orthopedic surgeons looking at fracture healing, cardiologists looking at the causes of heart disease and stroke, cancer specialists looking whether we can look at cell lines and the way they progress and we've looked at infectious diseases.

"That covers a large chunk of medicine and I expect we'll see [the scanners]hit the clinics at different times.

"It's going to be routine within a few years for a lot of point-of-care stuff."

The primary difference between the MARS scanner and other techniques is the level of detailed information it can record.

Anthony says the work is so cutting edge that components had to be built from scratch.

Dean Mouhtaropoulos

The MARS scanner was inspired by technology used at CERN, the World's Largest Particle Physics Laboratory.

"We did computer simulations to work out what we should be doing, then we had to come up with the designs, then manufacture it."

Dipanjan Pan, professor in chemical and biological engineering and radiology at University of Maryland Baltimore County, is an expert in nanomedicine and molecular imaging.

He collaborated with the MARS team for several years and says the3-D scanner has the potential to "dramatically change the ambiguity often found in black and white conventional CT imaging".

"Looking through MARS's proprietary photon counting CT 'magic lenses', you are visualising in colour the future of various biological processes as it merges with the present," he says.

"Their powerful reconstruction technique is astounding."

The technology has a range of uses from security and engineeringto physics and astronomy.

123rf

The traditional 2-D X-ray is good at showing solid objects like bones.

But the Butlers are focused on clinical applications and in July 2018 Phil became the first person to be scanned, with images generated of his wrist and ankle.

The next stage will be clinical trials next year when orthopaedic and rheumatology patients from Christchurch will bescanned.

Phil saysthe breakthrough is comparable to the first X-ray images in 1895 and the first low-resolution Computed Tomography (CT) in 1972.

"It's a major step. We went from 2-D to 3-D, now we're going from black and white to colour.

"The other thing that makes ours different from pretty much any other clinical system is we've got very high-resolution, basically 10 times the resolution of any other comparable technology."

Dr Diana Siew, associate director at MedTech Centre of Research Excellence at Auckland Bioengineering Institute, said the MARS X-ray scanner is a "game changer in medical diagnostics" because "it visualises what is happening in the body in a way that has not been achieved before".

"Different components of the body like fat, calcium, water and disease biomarkers show-up on the X-ray images in different colours, thus allowing a fuller and more accurate picture of a patient's condition," she says.

SUPPLIED

The new MRI scanner at Palmerston North Hospital had to be slotted through a hole in the wall when it was installed in April 2019.

"From a research perspective, this is exciting as it could underpin new understanding of disease onset and progression and be used to determine the efficacy of treatments.

"The MARS technology is a world's first and it is so exciting that it is happening in NZ."

As well as heralding a quantum leap in imaging capability, Anthony says the MARS technology will improve health treatment for Kiwis, as not everywhere has access to PET or MRI scanners.

"About half the people in rural New Zealand don't get appropriate cancer treatment, not because the country can't afford it but because the cancer centres are in large hospitals, the same is true for imaging," he says.

"If you are on the West Coast you cannot get a PET scan, you have to come over to Christchurch.

123RF

MRI scanners can record incredible detail but they are large and not widely available.

"So those access issues, we beat most of them because we use X-rays and they are very easy to have in a local practice, every dentist has got one."

Phil added: "One of the design goals for this system is to make it as easy to operate as a dentist's X-ray".

As well as the high cost of PET and MRI scanners, Anthony says there are other practicalities that make them less accessible.

"MRI requires rooms with big machines, you have to have liquid helium cooling it down, you can't put someone in with a pacemaker, certain vascular clips can't go in there [or] hip replacements," he says.

"With PET you have similar things, you have radioisotopes. In New Zealand we have one cyclotron in Wellington producing radioisotopes and they have to be flown around the country, so if it's a windy day in Wellington, no PET imaging can happen in the country."

Supplied

A 3-D image of Phil Butler's ankle, scanned in 2018.

MARS is operated from a secure area of University of Canterbury and as well as full-time staff, research is carried out by 15 PhD candidates.

Phil is in no doubt that a key component of the project's success is that it's based in Canterbury.

"If you look at the electronics or mechanical engineering skills of Christchurch, we can build anything," he says.

"We've got the skills to do it but the people also know each other, whereas if you go to a big city of several million, they can do it but they can't talk to their allied disciplines.

"That goes back to the farming industries, where people had to build their own machines and those skills of being able to build anything are all part of that."

Anthony agrees.

"If you go to really large research institutes they can be really skilled but they tend to have big silos. In New Zealand we tend not to operate that way.

Don Scott/Stuff

The Butlers, pictured here in 2010, examine coloured Iodine and Barium infused tissue.

"I think we're the sweet-spot in terms of size, where there's enough skill around that there's experts but we're not so big that we can't talk to each other."

Almost 15 years since the father and son team decided to embark on the research, they have made huge advances but there is still work to be done.

"If you look at where we were in 2006 or 2007 we were able to measure four colours but we had to do them one after the other, not simultaneously," Anthony says.

"We scanned the abdomen of a mouse, a pretty small object, and it [took] a day to image it and a month to do all the data reconstruction to get a picture to look at."

Day-to-day, Anthony is the company's chief medical officer and scientific lead.

Phil is the chief executive but, but according to Anthony, he still "does a lot of the technical work".

Working with family members can bring its challenges but Anthony says one of the advantages of partnering with his dad is the "innate trust" they have.

"It's actually a real pleasure," he says.

"I'm quite lucky, I didn't start working with him until I was in my early 30s, which meant I'd done all of my qualifications, established my own life.

"He had done many things himself and been pro-vice chancellor of the university and wanted to get more into practical applications so we founded this project together and that's been really nice.

"You're always going to have problems in any relationship but the fact that it's a family member gives you structure where you can actually work through problems and solve them and know that you're on the same team."

See more here:
Canterbury father and son's invention will revolutionise medical treatment - Stuff.co.nz

Just like any startup company in its early stages, the biggest challenge for female entrepreneurs and those from Israel's ultra-Orthodox and Arab sectors is raising capital. These entrepreneurs typically lack tech industry networking connections from the army, school, or childhood youth movements to help them overcome the financing challenge. "Expanding support for technological initiatives of Arab and ultra-Orthodox entrepreneurs provides a tailwind to their continued successful integration into Israeli high-tech, Dr. Ami Applebaum, chief scientist at the Israeli Ministry of Economy and Industry and the chairman of the Israel Innovation Authority, said.

According to Israels Central Bureau of Statistics, although women constitute approximately one-third of the world's entrepreneurs, only 14% of Israeli businesses are owned by women and just 4% of them employ other workers. According to data provided by Tel Aviv-based research firm IVC Research Center Ltd., only 7% of the technology startup founders in Israel during the last 17 years were women. OECD data reveals that startups managed by women receive 23% less money than companies headed by men and they have a 30% lower chance of achieving an exit. Furthermore, more than half of the female entrepreneurs in the technology sector choose to influence and promote initiatives in fields considered difficult to finance public administration, health, education, and social services. One of the many reasons for this is that initiatives meeting women's and community needs encounter difficulty in recruiting funding due to a lack of familiarity or a lack of understanding of the potential involved.

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Impact Investments That Create Employment and Change - CTech

Nanomedicine Market

Global Nanomedicine Market Professional Survey Report 2019 share manufacturing companies, product type, technological progress, geographical regions, and applications 2019-2024. The Nanomedicine report looks thoroughly at company strategies, and marketing, expenditure, company planning, and sales. The outlook of this sector has been examined in conjunction with the many challenges and growth opportunities. The Nanomedicine analysis exhibits a strategic report and providing market intelligence that is accurate, trusted and vital for its merchants or to implicitly any organization.

Major Players in Nanomedicine market are:Company 1Company 2Company 3Company 4Company 5Company 6Company 7Company 8Company 9Company 10

Most important types of Nanomedicine products covered in this report are:Type 1Type 2Type 3Type 4Type 5

Most widely used downstream fields of Nanomedicine market covered in this report are:Application 1Application 2Application 3Application 4Application 5

Overview of the Report:The report begins with a market overview and moves on to cover the growth prospects of the Nanomedicine markets. Global Nanomedicine industry 2019 is a comprehensive, professional report delivering market research data that is relevant for new market entrants or established players. Key strategies of the companies operating in the markets and their impact analysis have been included in the report. Furthermore, a business overview, revenue share, and SWOT analysis of theleading players in the Nanomedicine market are available in the report.

Nanomedicine Market: Regional Analysis Includes:

Target Audience of Nanomedicine Market 2019 Forecast to 2024 Market:

The content of the study subjects, includes a total of 15 chapters:

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Nanomedicine Market Global Industry to Record Significant Growth in the Near Future 2019-2024 - Market Research Sheets