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NOT-AR-23-022: Request for Information on Themes for the NIAMS … – National Institutes of Health (.gov)

Request for Information on Themes for the NIAMS Strategic Plan for Fiscal Years 2025-2029

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) supports research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases; the training of basic and clinical scientists to carry out this research; and the dissemination of information on research progress in these diseases. NIAMS is updating its Strategic Plan to help guide the research, training, and information dissemination programs it supports between fiscal years 2025 through 2029. The new Plan will focus on cross-cutting thematic research opportunities that position the Institute to make a difference in the lives of all Americans.Because public input is a crucial step in this effort, the Institute issued a Request for Information (NOT-AR-22-023) and hosted a meeting attended by approximately 160 researchers, patient representatives, and staff from other Federal entities to gain insight into topics that could be included in the new Strategic Plan.

Through this Request for Information, NIAMS invites feedback from researchers in academia and industry, health care professionals, patient advocates and health advocacy organizations, scientific or professional organizations, Federal agencies, and other interested members of the public on the Institutes distillation of the input received to date. Professional societies and patient organizations are strongly encouraged to submit a single response that reflects the views of their entire membership.

Please provide your perspective on the following potential cross-cutting themes, examples, and bold aspirations. NIAMS is particularly interested in suggestions for additional or alternative:

Examples:

Bold Aspirations:

Examples:

Bold Aspiration:

Note: Efforts to identify and reduce health disparities and provide all Americans with equitable access to clinical and epidemiologic studies and healthcare should be considered for NIAMS-funded research projects whenever possible.

Examples:

Bold Aspirations:

Examples:

Bold Aspiration:

Note: Consistent with the note under Health disparities and health equity, studies of lifestyle factors and environmental exposures should include efforts to identify and reduce health disparities and provide all Americans with equitable access to clinical and epidemiologic studies and healthcare whenever possible.

Examples:

Bold Aspiration:

Note: Consistent with the note under Health disparities and health equity, clinical and epidemiologic research should include efforts to identify and reduce health disparities and provide all Americans with equitable access to clinical and epidemiologic studies and healthcare whenever possible.

Examples:

Bold Aspiration:

Examples:

Bold Aspiration:

Note: Training and workforce efforts are essential for the pursuit of all cross-cutting thematic research areas in the new NIAMS Strategic Plan.

Examples:

Bold Aspiration:

Examples:

Bold Aspirations:

Responses to this RFI must be submitted electronically at https://rfi.grants.nih.gov/?s=654a7bc81e7ccb6f7d03d792.

Responses must be received by Monday, January 1, 2024.

Responses to this RFI are voluntary. Do not include any proprietary, classified, confidential, trade secret, or sensitive information in your response. The responses will be reviewed by NIAMS staff, leadership, and Advisory Council members. Individual feedback will not be provided to any respondent. NIAMS will use the information submitted in response to this RFI at its discretion and will not provide comments to any respondents submission. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted.The Government reserves the right to use any submitted information on public NIH websites, in reports, in summaries of the state of the science, in any possible resultant solicitation(s), grant(s), or cooperative agreement(s), or in the development of future funding opportunity announcements.

This RFI is for information and planning purposes only and shall not be construed as a solicitation, grant, or cooperative agreement, or as an obligation on the part of the Federal Government, the NIH, or individual NIH Institutes and Centers to provide support for any ideas identified in response to it. The Government will not pay for the preparation of any information submitted or for the Governments use of such information. No basis for claims against the U.S. Government shall arise as a result of a response to this request for information or from the Governments use of such information.

We look forward to your input and hope that you will share this RFI document with your colleagues.

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NOT-AR-23-022: Request for Information on Themes for the NIAMS ... - National Institutes of Health (.gov)

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UNSW picks up lion’s share of Royal Society of NSW Awards – UNSW Newsroom

Six UNSW researchers and professional staff have been recognised at the 2023 Royal Society of NSW Awards. Scientia Professor Helen Christensen has been awarded the James Cook Medal, which is the Societys highest honour. Professor Maria Kavallaris, Scientia Professor Kaarin Anstey, Dr Brendon Neuen, Professor Moninya Roughan and Mr Jason Antony have also received awards.

Overall, eight awards and medals, three scholarships and two service awards were announced for 2023 by the Royal Society of NSW at the 1318th Ordinary General Meeting, held at the State Library in NSW Wednesday night. The Open Lecture was delivered by UNSW Professor John Church, winner of the Societys 2022 James Cook Medal.

Interim Dean of UNSW Medicine & Health Professor Adrienne Torda applauded the UNSW winners on their success.

"I congratulate these extraordinary UNSW researchers for being recognised at the Royal Society of New South Wales Awards.Special congratulations to Helen Christensen for receiving the James Cook Medal. Helen is a truly deserving recipient as one of Australias leading mental health experts, she has made significant contributions to being able to identify and treat sufferers of this chronic disease through innovative digital treatments, Prof. Torda said.

All our winners are exceptional specialists in their fields. The annual Royal Society of NSW awards are among the oldest and most prestigious awards in Australia, and its an honour for so many of our scientists to be recognised.

UNSW Scientia Professor Helen Christensen, Board Director of the Black Dog Institute, has been awarded the James Cook Medal for outstanding contributions to science and human welfare in the Southern Hemisphere. Its the most prestigious award offered by the Royal Society of NSW.

Prof. Christensen is a leading expert on using technology to deliver evidence-based interventions for the prevention and treatment of depression, anxiety, suicide, and self-harm.

I'm very honoured to receive this prestigious medal. The work I do, alongside my colleagues, is all about making life better for those in our community facing mental health struggles. The Royal Societys award recognises that using science is one of the best ways to solve the tough problems we're dealing with today, Prof. Christensen said.

Read more: UNSW researchers awarded $10m in health funding

UNSW researchers have received the James Cook Medal nine of the last 10 times the medal has been awarded.

Professor Moninya Roughan. Photo: UNSW.

Professor Moninya Roughan from UNSW Science has been awarded the Clarke Medal for distinguished research in the natural sciences, conducted in Australia and its territories, in the fields of botany, zoology, and geology.

Prof. Roughan is an authority on the dynamics of the East Australian Current, ocean observationand prediction systems and their application to understanding western boundary currents and continental shelf processes. She leads the Coastal and Regional Oceanography Lab at UNSW.

I am truly humbled and deeply grateful to be the recipient of this prestigious award. This recognition is not just a reflection of my individual efforts but a testament to the collaborative spirit of the scientific community and every breakthrough stands on the shoulders of those who came before me. I am fortunate to have been guided by mentors, inspired by colleagues, and supported by my dedicated research team at UNSW, Prof. Roughan said.

"I believe that the truest achievement is in the positive impact my research has on the world and I hope that this recognition inspires future generations to explore the limitless possibilities in the ocean sciences and foster environmental stewardship."

Professor Maria Kavallaris. Photo: UNSW.

Professor Maria Kavallaris from UNSW Medicine & Health received the Walter Burfitt Award, for distinguished research in any area of the Medical and Veterinary Sciences and Technologies.

Prof. Kavallaris leads the Tumour Biology and Targeting Group at the Childrens Cancer Institute and is the founding co-director of the Australian Centre for NanoMedicine at UNSW. She has made seminal contributions to understanding the role of the cytoskeleton in cancer biology andis best known for identifying how tumour cells become resistant to commonly used chemotherapydrugs and how drug resistance can be reversed.

Read more:New treatment approach to selectively target cancer cells: study

Her studies have identified how some tumours can grow and spread in the body, and she has applied this knowledge towards the development of advanced diagnostics and therapeutics using nanotechnology.

I've dedicated my life to understanding and identifying effective treatments for cancer because I believe that everyone deserves a chance to survive. This award is a reminder that our work is making a difference, and it inspires me to continue pushing forward. This award is not just for me; it's for all the past and present brilliant students and researchers who I have had the honour of mentoring and working with, Prof. Kavallaris said.

Scientia Professor Kaarin Anstey. Photo: UNSW.

Scientia Professor Kaarin Anstey from UNSW Science has received the inaugural Award in the Social and Behavioural Sciences, which is for distinguished research in any area of the social and behavioural sciences including psychology, economics, management, and related disciplines.

Read more:Chef's kiss: brain-friendly cake shines light on cognitive decline

Prof. Ansteys research programs focus on cognitive resilience in ageing as well as prevention of dementia. She has developed new methods to assess risk of cognitive decline and dementia as well as non-pharmacological interventions to reduce these risks. Another focus of her work is on older driver safety and in this field, she has also developed and validated risk assessment tools and interventions.

I am excited and honoured to receive this inaugural award from the Royal Society of NSW and would like to thank my colleagues and team with whom Ive worked for many years, Prof. Anstey said.

Cognitive health is central to ageing well and I look forward to continuing to expand our knowledge in this field.

Dr Brendon Neuen from the George Institute of Global Health an affiliate of UNSW has been awarded the inaugural Ida Browne Early Career Medal. The Medal is awarded for contributions to knowledge and society in Australia or its territories by an individual from 05 years post-PhD or equivalent.

Dr Neuen is a nephrologist and Director of the Kidney Trials Unit at Royal North Shore Hospital. He is recognised for his expertise in cardio-renal-metabolic medicine. His work has directly informed more than 25 major international and national guidelines, position papers and scientific statements about optimal care for people with type 2 diabetes and kidney disease.

I am delighted and honoured to be the inaugural recipient of the Ida Browne Medal from the Royal Society of NSW. My work would not be possible without the generosity of patients and thededicationofstudy teams and investigatorswho made large-scale internationalclinical trialsa reality, Dr Neuen said.

I feel a deep sense of responsibility to ensure that this recognitionis translated intoa long and impactful career in clinical trialsthat improves the lives of people with type 2 diabetes and kidney disease worldwide."

Jason Antony. Photo: UNSW

Mr Jason Antony from the Industrial Relations Research Group atUNSW Canberra has received the Royal Society of New South Wales Citation, for significant contributions to the Society.

Since 2016, Mr Antony has been indispensable in the production of fifteen issues of the Journal & Proceedings of the Royal Society, and as editor and producer, of 28 issues of the Bulletin from 2020 to 2023.

Helping produce the Royal Societys Journal & Proceedings and Bulletinis a rewarding and enriching experience, Mr Antony said.

When a venerable institution recognises one'scontributions formally, it fills life with vim, vigour, and a renewed sense of purpose. I am immensely grateful to the Society, and to the myriad ofwise, wonderful people who have provided guidance and nurtured my skills over the years.

Read more about the Royal Society of NSW Awards 2023.

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UNSW picks up lion's share of Royal Society of NSW Awards - UNSW Newsroom

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Brain Study Suggests Traumatic Memories Are Processed as … – Slashdot

Traumatic memories had their own neural mechanism, brain scans showed, which may help explain their vivid and intrusive nature. From a report: At the root of post-traumatic stress disorder, or PTSD, is a memory that cannot be controlled. It may intrude on everyday activity, thrusting a person into the middle of a horrifying event, or surface as night terrors or flashbacks. Decades of treatment of military veterans and sexual assault survivors have left little doubt that traumatic memories function differently from other memories. A group of researchers at Yale University and the Icahn School of Medicine at Mount Sinai set out to find empirical evidence of those differences.

The team conducted brain scans of 28 people with PTSD while they listened to recorded narrations of their own memories. Some of the recorded memories were neutral, some were simply "sad," and some were traumatic. The brain scans found clear differences, the researchers reported in a paper published on Thursday in the journal Nature Neuroscience. The people listening to the sad memories, which often involved the death of a family member, showed consistently high engagement of the hippocampus, part of the brain that organizes and contextualizes memories. When the same people listened to their traumatic memories -- of sexual assaults, fires, school shootings and terrorist attacks -- the hippocampus was not involved.

[...] Indeed, the authors conclude in the paper, "traumatic memories are not experienced as memories as such," but as "fragments of prior events, subjugating the present moment." The traumatic memories appeared to engage a different area of the brain -- the posterior cingulate cortex, or P.C.C., which is usually involved in internally directed thought, like introspection or daydreaming. The more severe the person's PTSD symptoms were, the more activity appeared in the P.C.C. What is striking about this finding is that the P.C.C. is not known as a memory region, but one that is engaged with "processing of internal experience," Dr. Schiller said.

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Monoclonal Antibodies Market Size Worth USD 572.62 Billion in … – GlobeNewswire

Vancouver, Nov. 28, 2023 (GLOBE NEWSWIRE) -- The global monoclonal antibodies market size was USD 204.42 billion in 2022 and is expected to register a revenue CAGR of 10.8% during the forecast period. The global monoclonal antibodies market is poised for significant growth, driven by factors such as the rising adoption of personalized medicine, expanding regulatory approvals for monoclonal antibodies, and continuous technological advancements in biotechnology and immunology. These factors, along with the increasing prevalence of cancer and infectious diseases, are contributing to a surge in demand for effective and targeted monoclonal antibody-based therapies. The market witnessed substantial developments in 2022, with major players actively contributing to advancements in monoclonal antibody-based treatments. Notably, GlaxoSmithKline plc. (GSK) and iTeos Therapeutics announced a promising partnership for the development and commercialization of EOS-448, an anti-TIGIT monoclonal antibody, showcasing the potential for next-generation immuno-oncology therapies.

Despite the positive trajectory, challenges such as the impact of the COVID-19 pandemic on manufacturing processes, higher associated manufacturing costs, and a shortage of skilled professionals have hindered revenue growth. Recent safety concerns and FDA cautionary messages regarding specific monoclonal antibodies for COVID-19 treatment, especially in light of the omicron variant, have added complexity to the market dynamics.

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Key Market Insights:

Source Insights:

Indication Insights:

End-Use Insights:

Regional Insights:

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Scope of Research

MAJOR COMPANIES and Market Share Analysis

The global monoclonal antibodies market is fairly fragmented, with many large and medium-sized players accounting for the majority of market revenue. Major players are deploying various strategies, entering mergers & acquisitions, strategic agreements & contracts, developing, testing, and introducing more effective monoclonal antibodies solutions. Some major players included in the global monoclonal antibodies market report are:

Strategic Development

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Segments Covered in Report

For the purpose of this report, Emergen Research has segmented the global monoclonal antibodies market on the basis of source, indication, production type, end-use, and region:

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Hybrid Operating Room Market Size, Share, Trends, By Component (Surgical Instruments, Audiovisual Display Systems and Tools, Intraoperative Diagnostic Imaging Systems, Operating Room Fixtures), By Application, By End-use, and By Region and Country Forecast to 2028

Single Use/Disposable Endoscopy Market By Product (Endoscope, Visualization Systems, Endoscopic Ultrasound, Insufflator), By Application (Bronchoscopy, Urologic Endoscopy, Arthroscopy, GI endoscopy, ENT Endoscopy, Others), By End-use (Hospitals, Healthcare Centers, Clinics), and By Region Forecast to 2028

Nanorobotics Market Size, Share, Trends, By Type (Nanomanipulator, Bio-Nanorobotics, Magnetically Guided, Bacteria-Based), By Application (Nanomedicine, Biomedical, Mechanical, Others), and By Region Forecast to 2028

AI based Clinical Trials Solution Provider Market By Therapeutic Application (Oncology, Cardiovascular Disease, and Neurological Disease), By Phase, By End-use (institutes), and By Region Forecast To 2030

Veterinary Ultrasound Market, By Type [Two-Dimensional (2D), Three-Dimensional/Four Dimensional (3D/4D), and Doppler], By Product, By Technology, By Animal Type, By Application, By End-Use, and By Region Forecast to 2030

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GCRC C.E.O. Mike Robinson named Alignable Businessperson of the Year 2023 Santa Barbara County – EIN News

GCRC C.E.O. Mike Robinson named Alignable Businessperson of the Year 2023 Santa Barbara County  EIN News

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GCRC C.E.O. Mike Robinson named Alignable Businessperson of the Year 2023 Santa Barbara County - EIN News

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Assistant Professor of Practice in West Lafayette, IN for Purdue University

Details

Posted: 14-Dec-22

Location: West Lafayette, Indiana

Salary: competitive

Categories:

Physics: Physics

Sector:

Academic

Work Function:

Faculty 4-Year College/University

Preferred Education:

Doctorate

The Department of Physics and Astronomy in the College of Science at Purdue University invites applications for a non-tenure track faculty position at the rank of Assistant Professor of Practice. The successful candidate will support the learning and engagement activities of the Department, defined broadly.

Qualifications: Candidates must have a PhD in Physics or Astronomy or closely related field, with a track record and a commitment to teaching and engagement. Successful candidates will teach at undergraduate and graduate levels, participate in curriculum development for face-to-face and online courses, conduct professional development of teaching assistants, engage in scholarship of teaching and learning, including seeking external funding to support these efforts, dedicate time to committee work related to learning and engagement activities, contribute to recruitment and retention of students, and participate in departmental outreach efforts.

The Department and College: The Department of Physics and Astronomy has 60 tenured and tenure-track professors, 190 graduate students, and 280 undergraduates. The Department is engaged in research in astrophysics, atomic, molecular, and optical physics, biological physics, condensed matter, high energy, nuclear physics, and physics education, as well as university-wide multidisciplinary research in data science, nanoscience, photonics, and quantum information science involving the Birck Nanotechnology Center, the Purdue Quantum Science and Engineering Institute, and the Colleges of Engineering. For more information, see https://www.physics.purdue.edu/.

The Department of Physics and Astronomy is part of the College of Science, which comprises the physical, computing and life sciences at Purdue. It is the second-largest college at Purdue with over 350 faculty and more than 6000 students. With multiple commitments of significant investment and strong alignment with Purdue leadership, the College is committed to supporting existing strengths and enhancing the scope and impact of the Department of Physics and Astronomy. Purdue itself is one of the nations leading land-grant universities, with an enrollment of over 41,000 students primarily focused on STEM subjects. For more information, see https://www.purdue.edu/purduemoves/initiatives/stem/index.php.

Application Procedure: Applicants should apply electronically at https://careers.purdue.edu/job-invite/22139/

that includes (1) a cover letter, (2) a complete curriculum vitae, and (3) statement of teaching and learning.

Purdue University, the College of Science, and the Department of Physics and Astronomy are committed to advancing diversity in all areas of faculty effort, including discovery, instruction, and engagement. Candidates are encouraged to address in their cover letter how they are prepared to contribute to a climate that values diversity and inclusion. Purdue University, the College of Science, and the Department of Physics and Astronomy are committed to free and open inquiry in all matters. Candidates are encouraged to address in their cover letter how they are prepared to contribute to a climate that values free inquiry and academic freedom.

Additionally, applicants should arrange for three letters of reference to be e-mailed to the Search Chair at physpop@purdue.edu. Applications will be held in strict confidence and will be reviewed beginning January 30, 2023. Applications will remain in consideration until the position is filled. A background check will be required for employment in this position.

Purdue University is an EOE/AA employer. All individuals, including minorities, women, individuals with disabilities, and veterans are encouraged to apply.

About Purdue University

Physics explores the fundamental mysteries of nature...from how the universe was created, to how biological systems function, to how to create new forms of matter. The strength of Purdue's physics department is its internationally recognized research in the areas of astrophysics, high energy physics, geophysics, nanophysics, nuclear physics, sensor technology, biophysics and more. How chlorophyll and hemoglobin work, the structure of black holes, the search for fundamental particles, the precise dating of Stonehenge, and new sensors for homeland defense are a few of the topics that drive the research in our department.

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Assistant Professor of Practice in West Lafayette, IN for Purdue University

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