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Category Archives: Gene Medicine

CRISPR-Cas9 corrects hypertrophic cardiomyopathy gene mutation … – 2 Minute Medicine

1. The gene editing tool CRISPR-Cas9 was used to correct a mutant paternal MYBPC3 allele in human preimplantation embryos Continue reading

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How do you turn world-leading British science into medicines? – Telegraph.co.uk

Ministers will have their work cut out as the UK has too often failed to translate medical breakthroughs into blockbusters made in Britain. An example is monoclonal antibodies, a common component of biological drugs discovered at Cambridge University in the Seventies. It led to a Nobel Prize for the scientists involved and has since exploded into a field worth around 70bn globally today Continue reading

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Research reveals how estrogen regulates gene expression – Baylor College of Medicine News (press release)

Binding of steroid estrogen hormones to estrogen receptor (ER) in the cell nucleus triggers the sequential recruitment different coactivators to regulate gene transcription. Estrogen hormones regulate gene expression Continue reading

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Stanford Center Hopes to Take Stem Cell and Gene Therapies to a New Level – Sickle Cell Anemia News

The new Stanford Center for Definitive and Curative Medicine will fosterthe development ofstem cell and gene therapies for genetic diseases, including sickle cell anemia. More than280 million people around the world have diseases with genetic causes, experts estimate Continue reading

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In pain? For some, gene studies could provide a quick cure – WRAL.com

Raleigh, N.C. Many people spend years searching for a diagnosis of a debilitating medical problem, paying for treatments or surgery that don't help. Now, researchers at UNC say that, for some, recent advances in genetic testing could fix their problems once and for all Continue reading

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Test reveals possible treatments for disorders involving MeCP2 – Baylor College of Medicine News (press release)

The first step consisted of genetically modifying a laboratory cell line in which the researchers could monitor the levels of fluorescent MeCP2 as they inhibited molecules that might be involved in its regulation. Continue reading

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