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Category Archives: Gene Medicine

Two gene editing firms unveil cancer drug pacts as ASCO comes to a close – Boston Business Journal

Two gene editing firms unveil cancer drug pacts as ASCO comes to a close Boston Business Journal The research drew blowback from Intellia, which said that the claim about off-target effects lacked evidence and was based on a sample. In addition to Intellia and CRISPR Therapeutics, the other leading gene -editing firm is Cambridge-based Editas .. Continue reading

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New cancer medicine targets rare genetic flaw, finds study – Hindustan Times

An experimental cancer medicine called larotrectinib has shown promise in treating a diverse range of cancers in people young and old, researchers said at a major cancer conference in the United States. The treatment targets a genetic abnormality which is often found in rare cancers including salivary gland cancer, juvenile breast cancer, and a soft tissue cancer known as infantile fibrosarcoma which are particularly difficult to treat Continue reading

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Deploying therapeutic payloads to cells – MIT News

The founding mission of MIT may seem like an unusual meal-time story for a child. But when Mark Bathe was growing up, it was a regular topic of conversation around the dinner table. That is because Bathes father, mechanical engineer Klaus-Jrgen Bathe, was a long-standing, proud MIT faculty member, and regularly talked about MIT founder William Barton Rogers mission for the Institute Continue reading

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Drug Helps Fight Breast Tumors Tied to ‘Cancer Genes’ – The Tand D.com

SUNDAY, June 4, 2017 (HealthDay News) -- A twice-daily pill could help some advanced breast cancer patients avoid or delay follow-up sessions of chemotherapy, a new clinical trial reports. The drug olaparib (Lynparza) reduced the chances of cancer progression by about 42 percent in women with breast cancer linked to BRCA1 and BRCA2 gene mutations, according to the study. Continue reading

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Prepping for FDA filing, Loxo rolls up data on its site-agnostic cancer med larotrectinib – FierceBiotech

CHICAGOWhen Merck & Co.s Keytruda won approval last week to treat tumors based on a common biomarkerrather than the location in the body where the tumor originated, talk was thatthe true start of precision medicine had arrived. The $1.3 billion market cap biotech Loxo Oncology is hoping to be a part of that journey. At the American Society of Clinical Oncology meeting Saturday, Loxo posted the latest data for its experimental larotrectinib (LOXO-101), amedicationit hopes will treat an array of cancers innearly a dozen sites across the body. Continue reading

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Combination therapy targets genetic mutation found in many cancers – Medical Xpress

June 2, 2017 Credit: CC0 Public Domain A study at The University of Texas MD Anderson Cancer Center has shown promise for effective treatment of therapy-resistant cancers caused by a mutation of the RAS gene found in many cancers. Continue reading

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