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Category Archives: David Sinclair

Brave Cashel Community School get the better of St Augustine’s to set-up a Munster hurling final clash with Doon – TipperaryLive.ie

Munster Under-19B Post-Primary Schools Hurling Championship Semi-FinalCashel Community School 4-16 St Augustines (Dungarvan) 3-16

Sen Treacy Park was the venue for this semi-final with the conditions cool, but dry. If the conditions were on the chilly side the large crowd in attendance were not short of entertainment as both teams played out a dramatic game featuring thirty-nine scores and seven goals.

The first half was a tight and tense affair with both sides finding space and time on the ball hard to come by.

The Dungarvan school opened the scoring with points from the lively Willie Beresford and Johnny Bourke. Cashel responded with a free, but the Waterford men extended the lead back out to two with a fantastic score from Sam Fitzgerald. Cashel then hit the front with a flurry when hitting 1-2 during a three-minute blitz with the goal coming from Ben Ryan who reacted quickest when an effort at a point came down off the upright.

These scores settled Cashel, but a pair of Niall Buckley frees saw Augustines tie the game (1-2 to 0-5) with twenty-two minutes on the clock.

Both teams exchanged points from then until half-time before Stephen Browne slotted a good point, the other scores all came from dead balls.

The teams headed for the dressing rooms all square (1-6 to 0-9).

SECOND HALF

Cashel opened the second half full of purpose and intent. The Tipperary men hit an uninterrupted 2-3 during a twelve-minute blitz with the goals coming from Kevin Cleary and Conor ODwyer as well as a fine point form the dynamic Euan Ryan.

Daniel Moloney and ODwyer were now to the fore in Cashel's forward line and were helped by the movement of Cathal Quinn to leave the scoreline reading 3-9 to 0-11 points after forty-four minutes.

The men from the south coast did not roll over, however, and crept back into the game thanks to points from Buckley and Burke raising green flags - the second coming from a 21-yard free which saw Buckley take his tally to 1-8. The sides were now (3-11 to 2-14).

This Cashel team knew how to respond. A long-range free was batted out and the lightning fast reactions of Stephen Browne saw him rattle the net to reassert his side's lead. ODwyer dissected the posts with a free to give Cashel a much needed cushion going into the last ten minutes.

The drama did not end there though with Johnny Burke firing the game's seventh goal to claw his team back into the game (4-13 to 3-15) with five minutes of normal time remaining.

It was from here on that the large crowd really saw the true character of this Cashel team as their never-say-die attitude came to the fore.

Cashel kicked for home as Murphy won another crucial free and sub Reuben Bourke made a powerful run to set up the final score which sealed his teams passage to the Munster final.

Cashel had leaders all over the park and not least with defenders Ben Loughman, Toms Bourke, Brian g ODwyer, Conor Farrell and Callum Lawrence all contributing hugely. The athleticism and energy of Jamie Duncan was admired by all while Jack Currivan in goal worked many of his puck-outs to build attacks for his team. Captain Lorcan Carr and Euan Ryan linked play between defence and attack while also working tirelessly. All six starting forwards finished up on the score sheet which shows the variety of threat this team contains.

MUNSTER FINAL

Cashel Community School will take on Scoil na Tronide Naofa, Doon in the Munster Under-19B Post-Primary Schools Hurling Championship final on Saturday, February 15 at Leahy Park in Cashel when the prestigious Corn Thomais Mhic Choilm will be on the line.

The Doon team, which features eight Tipperary players from Cappawhite and ire g Annacarty, got the better of Borrisokane Community College in the semi-finals (3-21 to 2-15) while Cashel Community School proved too strong for St Augustines (4-16 to 3-16).

In the quarter-finals Cashel Community School accounted for Causeway Comprehensive (1-22 to 2-18) while the Tipperary outfit have also beaten Rice College, Ennis (1-17 to 0-8) and Coliste Chrost R, Cork (7-21 to 0-5) during their campaign.

Meanwhile Scoil na Tronide Naofa, Doon proved too strong for Scoil Phobal Roscrea (1-32 to 4-20) in the quarter-finals and Abbey CBS (1-16 to 1-15) in an earlier round of the competition. The Limerick school did lose to St Augustine's (2-8 to 1-13) during the group phase, but re-grouped before surging into the provincial decider.

MATCH DETAILS

Cashel Community School: Jack Currivan (Golden-Kilfeacle), Conor Farrell (Knockavilla Kickhams), Toms Bourke (Boherlahan-Dualla), Jamie Duncan (Knockavilla Kickhams), Lorcan Carr (Knockavilla Kickhams), Ben Loughman (Knockavilla Kickhams), Brian g ODwyer (Rockwell-Rosegreen), Euan Ryan (Boherlahan-Dualla), Callum Lawrence (Cashel King Cormacs), Ben Ryan (Knockavilla Kickhams), Daniel Moloney (Cashel King Cormacs), Stephen Browne (Knockavilla Kickhams), Cathal Quinn (Cashel King Cormacs), Conor ODwyer (Cashel King Cormacs), Kevin Cleary (Rockwell-Rosegreen). Subs: James Murphy (Boherlahan-Dualla) for B Ryan (40th), Adam Ryan (Rockwell-Rosegreen) for Cleary (50th), Reuben Bourke (Knockavilla Kickhams) for Carr (55th), Ned Ryan (Boherlahan-Dualla) for Farrell (60th). Panel Members: Ciarn Moroney (Fethard), Jack Breen (Knockavilla Kickhams), Michael OConnor (Boherlahan-Dualla), Ben Currivan (Golden-Kilfeacle), David Sinclair (Golden-Kilfeacle), Piric Brosnan (Cashel King Cormacs), Darragh Lacey (Boherlahan-Dualla), John Marnane (Rockwell-Rosegreen), Sen Ryan (Rockwell-Rosegreen), Eoghan Murphy (Cashel King Cormacs), Christopher Geraghty (Rockwell-Rosegreen), Ross Whelan (Cashel King Cormacs) and Michel Quinlan (Fethard).

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Brave Cashel Community School get the better of St Augustine's to set-up a Munster hurling final clash with Doon - TipperaryLive.ie

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BOYS SWIMMING: Tigersharks top Waconia in conference dual – Crow River Media

The Hutchinson boys swimming and diving team defeated Waconia 91-81 Thursday night.

Conner Hogan had a great meet for the `Sharks. Hogan won the 100 freestyle and had the best time in the backstroke. He also helped both the 200 medley and 200 freestyle relay teams take first.

Same with Noah Tague. Tague won the 200 IM and helped the 200 medley relay team take first.

Mattew Olberg came in first in the 500 freestyle and helped the the 200 freestyle relay team come in first as well.

Alex Oestreich just missed out on 200 points in the diving competition with 199.95.

The `Sharks had a large enough lead going into the backstroke that they exhibitioned the final three races.

This was a nice warmup for them before they head down to Minneapolis and take on True Team State meet on Saturday at the Jean K. Freeman Aquatic Center at noon.

Hutchinson 91, Waconia 81 (Jan. 23)

Individual Results:

200 medley relay: 1. Hutch A (Conner Hogan, Noah Tague, Tristin Nelsen, Alex Oestreich) 1:45.86, 3. Hutch B (Riley Yerks, Devon Bode, Gabe Stassen, Dane Thovson) 1:53.49

200 freestyle: 1. Samuel Sinclair (W) 1:50.71, 2. Matthew Olberg 1:53.35, 3. Thovson 2:02.83, 4. Max Einck 2:04.19

200 IM: 1. Tague (H) 2:09.22, 3. Nelsen 2:13.65, 5. Stassen 2:24.32

50 freestyle: 1. David Sinclair (W) 22.14, 2. Bode 24.09, 3. Oestreich 25.24, 4. Charlie Jenum 25.87, Ben Becker 26.44

1 mtr diving: 1. Oestreich (H) 199.95, 2. Cameron Wagner 183.80

100 freestyle: 1. Hogan (H) 51.42, 2. Yerks 57.73, 4. Wagner 59.70, Becker 1:03.22

500 freestyle: 1. Olberg (H) 5:09.89, 3. Thovson 5:24.79, 5. Einck 5:40.79

200 freestyle relay: 1. Hutch A (Hogan, Oestreich, Nelsen, Olberg) 1:37.56, 2. Hutch B (Stassen, Anthony Witte, Jenum, Einck) 1:44.54, 4. Hutch C (Jackson Kramer, Grant Kropp, Ethan Field, Wagner) 1:51.50

100 backstroke: 1. Alex Kearney (W) 1:07.51, Hogan 1:01.78, Yerks, 1:08.00, Witte 1:08.08

100 breaststroke: 1. David Sinclair (W) 1:03.70, Tague 1:06.91, Bode 1:07.44, Jenum 1:12.65

400 freestyle relay: 1. Wac A (Nathan Sannito, Lars Johnson, Samuel Sinclair, David Sinclair) 3:35.70, Hutch A (Olberg, Thovson, Tague, Bode) 3:40.62, Hutch B (Einck, Jenum, Field, Yerks) 4:00.59, Hutch C (Wagner, Carter Johnson, Kramer, Witte) 4:10.32

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BOYS SWIMMING: Tigersharks top Waconia in conference dual - Crow River Media

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David Sinclair on NMN and Epigenetics | | LEAF

Dr. David Sinclair, a Professor of Genetics at Harvard Medical School, is one of the most well-known researchers in the field of rejuvenation, and his lab is the beneficiary of a successful Lifespan.io campaign.

Today, Dr. Sinclair is releasing his book on Amazon, Lifespan: Why We Age and Why We Dont Have To, and on Wednesday, September 18, we hosted a special webinar with Dr. Sinclair as well.

David has recently appeared on shows such as Joe Rogan, not once but twice, the David Pakman show, and Tom Bilyeu. At International Perspectives in Geroscience, a conference hosted at Weizmann Institute of Science (Israel) on September 4-5, we had the opportunity to interview Dr. Sinclair about his work and his thoughts on the current state of research.

Back in February, you and a group of 16 researchers in the aging field went to the Academy for Health and Lifespan Research with the aim of promoting aging research, fostering the sharing of knowledge between scientists, and helping to guide governments and other key players in the industry. Could you please tell us a little more about the Academy and its current activity?

The Academy is a founding group of scientists who seek to understand the fundamental causes of aging and how to combat it. We have come together to build a society, a group of leaders around the world who will act as one voice to help shape not just the research, but public policy, future economic effects of the research, and medicines that are going to come from this field.

Do you think that aging is a disease or a syndrome or not? Whats your opinion on that?

Well, first of all, theres no correct answer. There is no law that says somethings a disease and something is not. Currently, the medical definition of a disease is something that causes a dysfunction or disability that happens to less than half of the population. Of course, aging happens to most of the population now, but I think that having a cut-off at 50% is arbitrary. Something that causes decline in functionality and eventual death should be worked on just as vigorously as something that only affects a minority of people.

Do you think that recognizing aging as a disease, in, say, the International Classification of Diseases makes sense in order to accelerate the development of new therapies addressing the root mechanisms of aging?

The World Health Organizations new definition of aging as a condition is helpful, but the real change will come when a leading country says that aging is a disease that can have a medicine approved for treatment. Right now, because aging is not a condition thats agreed upon by any regulator, drugs that may slow or reverse aging, and perhaps extend lifespan, healthy lifespan, for many years, doctors are very hesitant to prescribe those medicines. They follow the rule book. Metformin is a good example of a drug that is relatively safe and cheap and could potentially have a big benefit. But, because aging is not a disease, doctors rarely provide it to their patients until they actually become diabetic.

Basically, that means that the position of the government has to change and then once the government declares sort of a war on aging, then there could be some regulation changes, and then it may come to the point when doctors will be mentally ready to prescribe these drugs, right?

Thats right. Also, if aging is a prescriptable condition, then investment in aging-related drugs or longevity medicines will increase by orders of magnitude. The problem today is because aging isnt a prescriptable condition, drugs have to be developed for other diseases first, with the hope that then theyll be used more broadly.

Currently, medicine treats the symptoms, not the causes, of age-related diseases. Do you think that we might soon reach the point where therapies will be taken in a preventive manner to delay the onset of age-related diseases? What do you think might be the turning point for things to change? Basically, prevention is always a problem, even though its one of the most effective strategies, but we seem to never get there.

Well, theres a subset of the population, particularly in the US, but increasingly around the world, who are using the internet to educate themselves and are trying to take action before they become sick. Sometimes with medical supervision, sometimes not. Its a grassroots movement right now; for it to become mainstream, the regulations would have to change so that doctors can feel comfortable prescribing medicines to prevent diseases. But, if we dont change, then we will continue to practice whack-a-mole medicine and only treat one disease at a time after its already developed.

You travel the world a lot. Is there a country that you think is more forward-thinking in how aging is viewed and might take the first move to define aging as a directly treatable condition?

There are a few; the leading contenders right now are Australia, Singapore, and then the US and UK are also talking about it. The first country that does take this first bold step will reap the rewards of that with more investment and, of course, an increasingly productive and healthy population.

You name the countries that seem to have the highest life expectancy, actually. Do you think that its related to the understanding that the problem of population aging is becoming severe enough?

Thats exactly right. The countries that have a problem with the healthcare of the elderly have to do something because of the increased amount of elderly will only continue to raise the percent of GDP those countries spend; right now the US already spends 17%. Theyre not getting any younger, and their life expectancy isnt changing. So, for the US to really make progress, they need a new approach to medicine.

Lets talk a little bit more about your work. You are very well known for your work with NAD+ and its precursors; were often asked whether NR or NMN is better. However, the data seems to suggest that different precursors are more or less efficient in a tissue- or organ-dependent manner. Would it be fair to say that rather than asking which is better, we should instead consider these differences and that both may have their place?

Theyre very similar molecules, and both have been shown to provide a variety of health benefits in mice. That doesnt mean either of them will work to slow aging in humans, and thats why placebo-controlled clinical trials are required to know if one of them, or both of them, will work in certain conditions.

There has been a great deal of debate over the ability of NMN to pass through the plasma membrane to reach the interior of the cell. However, you and your team recently showed that under certain conditions, NMN can indeed enter the cell via a previously undocumented transporter without the need to change back to NR. Have there been any further developments with this? In particular, what does this mean for the efficiency of NMN, given its close proximity to NAD+ in the salvage pathway?

The NMN transporter was recently published by Shin Imais group; I wrote a commentary about it. Im aware of work thats not yet published by a few different labs, looking at how these molecules travel through the body of a mouse. The conclusion is that some tissues have transporters, some dont. It can even vary depending on where in the gut youre talking about. I think, in the end, whats going to happen, like most areas of science, is that everybodys right; it just depends on what youre talking about.

There is a number of human trials in progress for NMN, including one at Brigham and Womens Hospital. Can you tell us anything about that, and when might we expect to see some results?

Those studies began over a year ago, and they are currently Phase 1 safety studies in healthy volunteers. Next year, the plan is to test the pharmaceutical product in a disease area, most likely a rare disease, but also in the elderly to see if we can recapitulate some of the results weve seen in mice, such as increased blood flow and endurance.

Another area that you are involved in is partial cellular reprogramming to reverse age-related epigenetic alterations in cells and tissues. This is a topic that we have written about in the last year or two. Given the success of Belmonte and his team, and the enthusiasm for the approach in general, it really seems to have great potential. Can you please tell us a little bit about this approach and the approach that you are taking and how youre progressing so far?

For 20 years, weve been working on epigenetic changes as a cause of aging, starting with work in yeast and now in mammals. Weve developed viral vectors and combinations of reprogramming factors that appear to be much safer than the Belmonte work, and weve used them to reprogram the eye to restore vision in mice with glaucoma and in very old mice.

Some people argue that epigenetic alterations are similar to the hands of a clock and they only reflect aging, making them not an underlying cause but rather a consequence; do you consider them a cause or a consequence, and when partial programming is initiated, should it be considered to be actual rejuvenation?

Currently, it is believed that the clock is just an indicator of age and not part of the actual aging process, but our recent work that we deposited on bioRxiv strongly suggests that the process of reversing the clock doesnt just change the apparent age of the body, it actually reverses aging itself by restoring the function of the old cells to behave as though theyre young again. Therefore, the clock may not just be telling time; it may actually be controlling time.

That sounds fascinating. So, its actual rejuvenation, right?

Its early days, but this appears to be as close to rewinding the clock and rejuvenating at least parts of the body than anything that weve worked on before.

Back in 2016, when Belmonte and his colleagues demonstrated that partial cellular reprogramming in mice was possible, he estimated that such approaches might reach the public in the next decade. Do you think that we are on track for this to happen?

Were now more than on track. Were actually ahead of schedule. We found an apparently safe way to reprogram tissues, complex tissues, and there are at least two companies now expecting to start clinical trials within the next two years in humans.

Can you tell us a little bit more about that, or is that secret for a while?

One of the companies is called Iduna, and I formed this company with Steve Horvath, Belmonte, and Manuel Serrano in Spain. We have the funding to start a clinical trial next year.

Partial reprogramming is altering ourselves at the cellular level; how do you think the general public might react to such an idea, in your view? Is this going to be a real hurdle to getting people on board with using these treatments?

I found that everyone who hears these results of the Belmonte lab and of my lab is extremely excited because its a very simple but powerful concept of rewinding the clock, and I dont know of anybody who has said that we shouldnt go faster in trying to develop this technology.

In general, whats your usual way of overcoming the initial skepticism regarding the idea of healthy life extension? Because there is this problem with life extension, that people sometimes react weirdly to it.

Ive faced that my whole career since I started; theres always going to be a group of individuals who dont believe that humans are capable of certain things. It was the same with flying back in the early 20th century. I think we know enough now about how aging works and how to slow it and possibly reverse it that its going to be possible in our lifetimes to have a big impact on our healthspan and probably lifespan. Anybody who thinks that its not doesnt know how fast science is moving.

Whats your usual way to deal with skepticism; do you have some favorite arguments?

Mostly, I just go back to the lab and do better research and let the data speak for itself. There are a lot of people who wont be convinced until they see the actual experiments redone many times. What Ive done in the past two years is Ive put all my ideas and the advances in the field into a book, so Im hoping that this book will convince the skeptics or at least make them think hard about whats possible with their lives, what they can do now, and what soon should become possible.

Wonderful. Actually, my next question was about this book; could you please tell us a little bit more about it and what the readers should look forward to.

Lifespan takes the reader on a journey through history, looking at the endeavor of humans to try to live longer and using that historical perspective to look at todays situation and project into the future. The book also takes readers on a journey through the very cutting edge of aging research and things that the reader can do right now to take advantage of these new discoveries in their daily lives with changes in their daily activity, what they eat, when they eat, but also medicines that are currently available on the market that may extend lifespan. The last chapter is about where we are headed, what are the medicines that are in development, and then when these drugs become available, what does the world look like? Is it a better place or a worse place, and how will our lives change?

Wow, that sounds like a book that I would really like to read. You look pretty amazing for being 50 years old. Im 40, and I think you look better than me. Are you doing something to support your health, to feel better, to be more productive and to age slowly?

Im doing an experiment right now in my body. My father, my wife, and my dogs. Its voluntary, of course; my brother recently complained that he was being treated as the negative control in the experiment. I believed in the research and known the risks to be low, so, starting with resveratrol in 2003, I started taking that and Im still taking it, and Ive added to that NMN and some metformin as well. I try not to eat too much. I should exercise more. What I do, and what Ive learned works for me, and for members of my family, is also written down in detail in my book. So, if people would like to know it, they can read it.

Finally, is there a question that no one ever asks you and that you would like us to ask?

Am I afraid of dying?

Are you?

No.

Why not?

Ive been in situations where I thought I could die, planes that have lost their control, that kind of thing. I dont get nervous; Im not worried about that. The reason that Im doing what Im doing is Id like to leave the world a better place than I found it. Im also very curious, Id like to see what we can discover and what the future holds for all of humanity, not just for longevity, but the future of the planet. See if we can point humanity in the right direction and away from the bad scenarios that we seem to be on right now.

We would like to thank Dr. Sinclair for taking the time to make this interview with us and for answering our questions.If you would like to learn more about his work, you may be interested in watching the special webinar we did with Dr. Sinclair in September 2019 which you can see below.

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David Sinclair on NMN and Epigenetics | | LEAF

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Meet the people who think soaking in a frozen Minneapolis lake is the secret to good health – Minneapolis Star Tribune

Ponce de Lens search for the fountain of youth in Florida is just a legend.

But about 1,500 miles to the north, in the icy waters of Cedar Lake in Minneapolis, dozens of people think theyve found the next best thing.

On a recent Sunday around 9:30 a.m., a diverse group of about 20 people dressed in swimsuits trekked to a spot near the shore on the west side of the lake and immersed themselves in an 8-by-12-foot rectangular hole cut in the ice. Later in the day, another group of people gathered to do the same thing.

This isnt a once-a-year, get-in, get-out, New Years Day plunge for Instagram bragging rights.

This is something that happens every Sunday throughout the winter.

Some people come several times a week, and stay for a good, long soak of five, 10, 15 minutes or more. Except for the knit hats, they look like they could be relaxing in a hot tub as they stand in water that ranges from waist- to neck-deep.

Called cold therapy or cold thermogenesis, ice-water bathing is a practice that biohackers and assorted others believe makes them healthier.

The Twin Cities Cold Thermogenesis Facebook group, which was created in 2016, claims the frigid dips do everything from increase testosterone in men to boosting brown adipose tissue. (The so-called brown fat or good fat may be helpful in combating obesity because it burns calories to create heat.)

Cold-water immersion also strengthens the immune system, according to Svetlana Vold, a part-time firefighter and ultramarathon winter bike racer from St. Louis Park, who organizes the Sunday morning cold-immersion session.

Vold and others say chilling out in the water combats inflammation, helps them sleep better and improves their focus and endurance. Some said theyre inspired by Wim The Iceman Hof, a Dutchman famous for his breathing and cold exposure technique called the Wim Hof Method.

The Cedar Lake group would probably meet the approval of David Sinclair, a Harvard genetics professor and longevity expert who thinks that cold exposure may help slow the aging process.

Maria OConnell, the organizer of the afternoon session, has been immersing herself in an ice-filled horse trough in her backyard since 2011. Initially its a little uncomfortable, she said. You end up getting better the more you do it.

But many say the frigid dunks are a mood-altering, even pleasurable experience.

It hurts so damn good, said Stephen McLaughlin, a 61-year-old Minneapolis resident. You are just completely present.

It makes me happy. I think its adrenaline, said Allison Kuznia, 42, of Minneapolis.

Its kind of a treat to go out and get really cold, said Nick White, 46, of Minneapolis. It gives you a feeling of euphoria.

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Hard work and dedication honored – Union Daily Times

UNION COUNTY The year 2019 was a busy and challenging one for the Union County Sheriffs Office which earlier this month honored its employees at its Annual Breakfast/Awards Banquet during which Sheriff David Taylor reviewed the year and those challenges as well as a continuing problem his office faces.

The banquet was held on Wednesday, January 8, and the employees of the Sheriffs Office were treated by Taylor to breakfast in recognition of their hard work and dedication during 2019.

As in previous years, awards were presented to Sheriffs Office personnel who excelled during the preceding year. Those receiving awards for excelling in the performance of their duties in 2019 were:

Major John Sherfield and Dr. John Flood Special Response Team Award

Deputy Kristen Spencer Deputy of the Year

Investigator Roxie Belue Investigator of the Year

911 Dispatchers Robert Garner and Nikia Brannon Dispatchers of the Year

A Year In Review

Like its predecessors, this years banquet was also a time for taking stock of the previous year, and Taylor did just that, giving a detailed presentation of A Year in Review.

Shootings

Violence, including violence involving law enforcement personnel, is something all law enforcement agencies must deal with as they serve and protect their respective communities and that was the case in 2019 for the Sheriffs Office which had to deal with two officer involved shootings. In his remarks, Taylor said that the number of officer involved shootings in 2019 was unprecedented for his office, but is a reflection of the realities of modern day society.

This is a sign of the times we are living in today, Taylor said. I cannot remember ever having this to happen in the history of Union County.

Investigations

The investigation of crime is one of the major responsibilities of law enforcement agencies and there was plenty for the Sheriffs Office to investigate in 2019, just not quite as much as in 2018.

Taylor said that the number of cases assigned to investigators of the Sheriffs Office declined slightly from 730 in 2018 to 705 in 2019.

Though the number of cases needing to be investigated declined between 2018 and 2019, Taylor reported that the Sheriffs Office saw a significant increase when it came to illegal drugs with 7,514 grams of Methamphetamine seized in 2019 compared to 252 grams in 2018. The amount of Heroin seized by the Sheriffs Office also increased, going from 9 grams seized in 2018 to 49 grams seized in 2019.

The amount of overall crime is symbolic to the amount of drug use in the county, Taylor said.

Special Units

2019 was also a challenging time for the special units of the Sheriff Office: the Special Response Team (SRT) and Bloodhound Unit and K-9 Drug Unit and their deployments during the year.

Taylor the SRT was deployed 10 times in 2019 compared to 7 in 2018 and he said he believes that in the future the SRT will grow in personnel and call-for-service due to the volatile times we are living in.

As for the Bloodhound Unit, Taylor said that in 2019 it was deployed 37 times, up two from 35 deployments in 2018.

These units stay extremely busy throughout the year, Taylor said. If they are not out running calls then they are training.

Of the 37 deployments in 2019, Taylor said 23 resulted in successful captures compared to 17 in 2018. In addition, Taylor said the Bloodhound Unit also recovered 4 weapons and seized $10,000 in currency in 2019.

Concerning the K-9 Drug Unit, Taylor said it was only deployed 14 times in 2019 compared to 51 in 2018. He said this was due to the handler assigned to the unit leaving in early 2019 and the Sheriffs Office having to train and certify another deputy to take over.

Civil Papers And Arrest Warrants

The year also saw an increase in Civil Papers and Arrest Warrants.

In 2019, we served 3,599 Civil Papers versus only 3,520 in 2018 while warrants were up slightly, Taylor said. In 2019, we served 1,828 Arrest Warrants compared to 1,646 in 2018.

While he praised the efforts of all of his deputies for their work serving those Civil Papers and Arrest Warrants, Taylor singled out Deputy Russell Roark for special praise.

Deputy Roark does an outstanding job serving papers for the Sheriffs Office, Taylor said. His knowledge of people helps because he is able to connect with them and locate people that otherwise dont want to be found.

911

The Union County Emergency Services/911 Dispatch Center is also part of the Union County Sheriffs Office and 2019 was a very busy year for it as well even though, as Taylor pointed out, the actual number of calls and dispatches were down slightly from 2018.

In total, we dispatched 33,533 calls for the Sheriffs Office, City Public Safety, EMS, Union County Fire, and Highway Patrol, Taylor said. These numbers were down from 36,204 in 2018.

Our dispatchers answered a total of 69,927 calls through the 911/Administration lines last year, he said. During 2018 they answered 73,392 calls.

Losing Personnel

Taylor concluded the program by thanking the personnel of the departments of his office for all their hard work and dedication to the citizens of Union County, but also pointed out that his office is having trouble retaining trained personnel.

I know that each of you are overworked and underpaid and hopefully this will be addressed by county council in the near future, Taylor said. We are constantly losing trained personnel to other agencies due to low pay.

The banquet was then closed with a prayer offered by Union County Councilman David Sinclair and Taylor offered his best wishes to all those in attendance.

Photo courtesy of the Union County Sheriffs Office Union County Sheriff David Taylor presents Investigator Roxie Belue with the Investigator of the Year Award for 2019. Belue was one of several Sheriffs Office employees to receive awards for their service in 2019 at the Sheriffs Offices Annual Breakfast/Awards Banquet held January 8.

Photo courtesy of the Union County Sheriffs Office Union County Sheriff David Taylor presents 911 Dispatcher Robert Garner with the Dispatcher of the Year Award for 2019. Garner was one of several Sheriffs Office employees to receive awards for their service in 2019 at the Sheriffs Offices Annual Breakfast/Awards Banquet held January 8.

Photo courtesy of the Union County Sheriffs Office Union County Sheriffs Office Investigator Scott Coffer (left) presents Major John Sherfield (right) with the Special Response Team Award for 2019. Sherfield was one of several Sheriffs Office employees to receive awards for their service in 2019 at the Sheriffs Offices Annual Breakfast/Awards Banquet held January 8. Dr. John Flood, a volunteer, was also honored with the Special Response Team Award but was unable to attend the banquet.

Photo courtesy of the Union County Sheriffs Office Union County Sheriff David Taylor presents Deputy Kristen Spencer with the Deputy of the Year Award for 2019. Spencer was one of several Sheriffs Office employees to receive awards for their service in 2019 at the Sheriffs Offices Annual Breakfast/Awards Banquet held January 8.

Photo courtesy of the Union County Sheriffs Office Union County Sheriff David Taylor presents 911 Dispatcher Nikia Brannon with the Dispatcher of the Year Award for 2019. Brannon was one of several Sheriffs Office employees to receive awards for their service in 2019 at the Sheriffs Offices Annual Breakfast/Awards Banquet held January 8.

UCSO employees recognized; Sheriff reviews 2019

This story courtesy of the Union County Sheriffs Office.

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Hard work and dedication honored - Union Daily Times

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The Race To Find A Cure For Aging – Medium

We want to look & feel young again, and every year we spend hundreds of billions of dollars on beauty serums, cosmetic surgery, and exotic supplements in the hopes of appearing more vibrant, healthy, and desirable.

All of those products, procedures & pills only cover up the symptoms of aging they do nothing to address the cause. While medicine does help us to live longer, at best it has only slowed the ravages of time, and an aging population is driving demand for alternatives to the gradual decline into senescence.

Aging, once thought to be inevitable, is being challenged. For the first time in history, biomedical innovators are starting to view it in a disease model, and not as an inevitability of life and medical science is working to find a cure.

Here are three stories of people from different walks of life who share a singular goal theyre actively working to extend their own lifespans, and sharing what theyve learned on how to achieve it:

Dr. David Sinclair says the solution is to get your NAD+ levels up and hes offering detailed, practical advice on how to do it. In lengthy interviews with Joe Rogan & Rich Roll, as well as his recent book, he discusses the health benefits of intermittent fasting, limiting sugar & red meat, and eating plenty of vegetables but for Sinclair, thats only the beginning.

Sinclair is an award-winning Australian biologist, professor of genetics, and Founding Director of the Paul F. Glenn Laboratory for the Biological Mechanisms of Aging at Harvard University.

His team of 30+ scientists is deeply engaged in studying the mechanisms involved with aging & senescence, and treatments to potentially reverse them. One of the promising life-extension supplements theyve identified is Metformin an inexpensive blood sugar medication that may extend the human lifespan by as much as 10%.

In addition to Metformin, Sinclair is bullish on the prospects of NMN (nicotinamide monomucleotide) for life extension. This vitamin B-3 derivative converts easily into NAD+ inside your cells, which is claimed to improve cellular function and offer rejuvenating effects seen in human clinical trials.

Sinclair claims to have reversed aging in lab mice, and also claims to have knocked more than two decades off his biological age, as well as boasting online that he has the lung capacity, cholesterol and blood pressure of a young adult and the heart rate of an athlete.

If hes right, aging can reversed with NAD+ boosting supplements and thats a big step in a cure for aging and the diseases that come with it.

Others, like Elizabeth Parrish, the CEO of BioViva Sciences, have taken a different route: she underwent experimental gene therapy to lengthen her telomeres & reduce muscle wasting back in 2016, and claims her health has improved since the treatment.

According to Wikipedia, independent testing by SpectraCell Laboratories had revealed Elizabeth Parrishs leukocyte telomere length had been extended from 6.71kb to 7.33kb but in 2018, she reported further lengthening in her telomeres up to 8.12kb, along with an overall growth in muscle mass.

A telomere is a region of repetitive nucleotide sequences at the end of each chromosome that protects it from damage and telomeres get shorter as we age, leading to a variety of aging-related diseases. The initial 10% increase of Parrishs telomeres has been roughly compared to her cells becoming 20 years younger.

However, critics such as Dr. Bradley Johnson at the University of Pennsylvania have questioned her results, stating, Telomere length measurements typically have low precision with variation in measurements of around 10 percent, which is in the range of the reported telomere lengthening apparently experienced by Elizabeth Parrish.

Meet Jim Green, patient zero in a one man experiment in radical anti-aging. He lacks the Sinclair teams funding and cant bioengineer retroviral delivery systems like the Parrish team, but what he lacks in budget he makes up for in courage, innovation & perseverance.

A few years back, Jim decided to tackle aging head-on, and started doing intense research into published scientific papers on aging, cellular senescence, and supplements that led him to a rigorous health regime that he claims has literally reversed his aging.

Jims published a collection of links and notes to all of his papers online, and from talking with him personally several times I can tell you that hes been more than diligent about his research. Josh Mitteldorf also interviewed him recently, and in that interview Jim talked at length about his use of first a nutraceutical called TA-65 and later Astragalus Root Extract as a telomerase activator to give new life to old cells.

Jim has taken the hard road: consuming copious amounts of Astragalus extract along with countless other supplements and a daily exercise routine thats visibly reversed most signs of his aging including his seeing his gray hair regain its youthful color (no, he doesnt dye it, thats natural).

Rather than trying to hide the signs of aging with makeup or plastic surgery, innovators like Sinclair, Parrish & Green have taken action to turn back the clock in the hopes of not only living longer but also living better.

Sinclair has spoken numerous times about aging leading to a tragic loss of human capital & potential that up until now weve taken for granted, but if the research that these innovators are pursuing bears fruit, then it may no longer be our inevitable fate.

Whatever the results of their experiments may ultimately be, their research alone is a testament to our shared desire to stop the sands of time from passing & make the most of every moment that we have.

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The Race To Find A Cure For Aging - Medium

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