Search Immortality Topics:

Page 11«..10111213..»


Category Archives: David Sinclair

Southland couple join volunteers to help future proof Southland A&P Show – Stuff.co.nz

John Hawkins/Stuff

Southland A&P Show officials Vic and David Sinclair help set up for the big event on Saturday.

Vic Sinclair has gone from anexhibitor to avolunteer to help ensure the future of theSouthland A&P Show.

After Sinclairand her children exhibited for the first timein2018, she and husband David decided to become more involved with the show.

"Events like the show can only be run by committed volunteers ... you get a lot of satisfaction from volunteer work," Vic said.

"We want the show to have a future so our kids can participatein it.

"It's something our kids can connect to and it links to the agricultural roots of Southland."

READ MORE:* Brothers and their stock in limelight at Winton A&P Show* Shaky start to life for ribbon-winning fawn* 'Suffer the consequences': Aero club committee dealing with employment dispute threatened* Southern farmer wins sheep award with Hampshire lamb gore show* Revitalised Southland A&P Show shines with new activities and events

The Sinclairs are marshalls for the entertainment and tradesections, while David is also vice-president for the 152nd show in Invercargillon Saturday.

John Hawkins/Stuff

Southland A&P Show committeemen - Noel Hamilton (50 years' service) left, Graham Calder (35) and Owen Anderson (42) - have been officials of the organisation for a combined total of 127 years.

Entertainment and business/trade displayswere sections of the show identified as expansion areasin a 2018 strategic report. The report was commissioned by the show executive.

A new marketing approachlast year saw an increase in business/trade displays, craft stalls, live musicandperformances. Numbers are high again this year and forthe first time,a lifestyle block section will be operating.

Show president Paula Bell said the report provided important information to future proofingthe annual event. It helped attract about 5000 people last year and she expecteda similar number, if not more,with fine weather on Saturday.

Meanwhile, long serving committeemen Noel Hamilton (50 years), Graham Calder (35) andOwen Anderson (42) have contributed to the showfor a total of 127 years.

"The show gives town families a touch of the country ... it lets them see what we do," Hamilton said.

Hamilton and Calder are sheep marshalls and the latter is sometimes surprised by children's comments.

"You talk to them [and somesay] they've never been up close to a sheep before," Calder said.

John Hawkins/Stuff

A caterpillar made out of hay bales, positioned at the entrance to the Southland A&P Show's venue in Invercargill, is part of the marketing for the event on Saturday. Show president Paula Bell is with Kurt Wilson who painted the caterpillar.

He and another breeder jointly owned the ram that was last year'sSupreme Champion Sheep. A ram, entered solely by Calder, won the title in 2016.

"I'd been trying for 40 years to win it and I got it.

"It makes it worthwhile when you get the top prize."

See the original post:
Southland couple join volunteers to help future proof Southland A&P Show - Stuff.co.nz

Posted in David Sinclair | Comments Off on Southland couple join volunteers to help future proof Southland A&P Show – Stuff.co.nz

Health inequality in England was bad. It has got worse – The Economist

The Marmot Review revisited ten years on

Feb 27th 2020

TEN YEARS ago the Marmot Review, a study commissioned by the government, asked a big, complicated question: why do some people in England live longer, healthier lives than others, and what can be done to reduce the gap? The answer it found was simple. Some people lived longer because they were better-off. To change this, it concluded, the government would have to reduce social inequality.

A new report by its author, Sir Michael Marmot of University College London, reviews the past decades changes. The numbers speak for themselves. In the three decades leading up to the first report, life expectancy at birth for men increased by a year every four years. Between 2011 and 2018 that rate slowed to a year every 15 years. For women the decline was even starker, from a year every five-and-a-half years to one every 28 years. And for the very poorest women, things have gone backwards. Life expectancy for those in the most deprived areas has declined by 0.3 years from 2010-12 to 2016-18. All women born later in the past decade are expected to have fewer healthy years than those born at the start of it.

Moreover, both men and women under the age of 50, particularly between 45 and 49, have seen mortality rates tick up (see chart). Sir Michael suggests that this could be related to suicide, alcohol use and rising drug toxicity, making it the British version of rising mortality rates among poor Americans, termed deaths of despair by Anne Case and Sir Angus Deaton, two economists who study the phenomenon.

What happened? The report stops short of putting the blame squarely on austerity, though it notes government spending has declined sharply in the past decade. One reason women may have suffered more than men is that spending cuts hit them harder. Research by the House of Commons library found that the majority of reductions have been borne by women, because the benefits they were likelier to receive saw deep cuts. Regional differences matter too. Poorer areas in the north are even more likely to have worse health than those in the south-east. I invite you to speculate that it is highly likely that some of these [cuts] will have had an adverse effect on health, says Sir Michael.

Yet the link between austerity and poor health is hard to pin down. David Sinclair of the International Longevity Centre, a think-tank, points out that several European countries underwent a period of austerity in the 2010s without drastically worsening health outcomes. And increases in life expectancy have slowed across the rich world, notes David Buck of The Kings Fund, another think-tank, though the slowdown in Britain has been sharper than most. Both Davids agree with Sir Michael that to improve public health governments must spend not just on health services but also on education, child support and community services. The health secretary, Matt Hancock, also welcomed the report. He said were committed to levelling up, and levelling up, and levelling up. He said levelling up four times I think, says Sir Michael, referring to the governments plan to boost poor parts of the country. And in case I hadnt got it: levelling up.

This article appeared in the Britain section of the print edition under the headline "Groundhog day"

Read more:
Health inequality in England was bad. It has got worse - The Economist

Posted in David Sinclair | Comments Off on Health inequality in England was bad. It has got worse – The Economist

Movers and Shakers Week Ending 2.28.20 – milehighcre.com

Rodney Anderson

Alliant National Announces Addition of Executive Vice President and National Agency Manager

Alliant National Title Insurance Company, a unique title insurance underwriter that partners with independent agents to improve their competitive position in the marketplace, announced that Rodney Anderson has been promoted to executive vice president and national agency manager, effective immediately.

Anderson will expand his current responsibilities for developing, marketing and managing Alliant Nationals Southwest Region Agency operations to include national market expansion and oversight of the companys 32 licensed state agency operations.

Anderson will be a member of the senior executive leadership team working to aggressively expand Alliant Nationals footprint.

I am honored that our CEO and ownership group, Presidio Partners, has placed their trust in me with such a key role within Alliant National, says Anderson. Throughout my career I have worked to support the independent agent, and I look very forward to working with the agency team assembled at Alliant National to help independent agents across the country.

Anderson is a seasoned real estate and title insurance industry expert with over thirty years experience in agency operations as the current Southwest regional manager for Alliant National, former co-owner of an independent title agency, and agency operations manager for a national independent agency. In addition, Mr. Anderson served three full terms as a State Representative in the Texas Legislature.

It is not often one gets the opportunity to work side-by-side with an industry professional of Rodneys caliber, says David Sinclair, Alliant National president and CEO. His unique experience combined with his passion for independent agents makes him the perfect person to lead our agency team, particularly at this juncture of accelerated company growth.

Alliant National distinguishes itself from competitors by combining strong underwriting capability with independent agents in-depth knowledge of local markets. The result is a nationwide network with deep roots in local communities, and a wealth of expertise that is flexible, nuanced and continuously growing.

Gensler Promotes 9 in Denver

Gensler, a global architecture, design, and planning firm, announced the promotion of nine in its Denver office.

Juan Padilla

Bekah Wagoner

Austin Zike

Juan Padilla,Rebekah Wagoner,AIA, LEED-AP, and Austin Zike, NCIDQ, IIDA, RIDwere promoted to associate.Juan Padilla is an architectural designer with experience across workplace to lifestyle project types.Rebekah Wagoner is an architect with 10+ years of experience with a passion for sustainable solutions for the built environment. Austin Zike is a senior project manager with 20+ years of experience successfully delivering large, complex projects across many sectors of workplace design.

Joy Hughes

Ronnie Leone

Erin Vinezeano

Joy Hughes, AIA, Ronnie Leone, IIDA, ErinVinezeano, AIA, and Michael Yeager, AIA were promoted to senior associate. Joy Hughes has been an architect with Gensler for 20 years and is a regional leader forthecritical facilities practice area.Ronnie Leone is an interior designer with 10+ years of experience designing award-winning creative workplaces for technology and financial services firms.She is also takingon a new role as Co-Studio Director. ErinVinezeano is an architect and interior designer with 10+ years of experience in a wide range of project types, from professional services to technology workplaces, including multiple nationally publicized workspaces.Michael Yeager is anarchitect with 20+ years of experience in a range of project types, recently leading three major development projects in Denver.

Michael Yeager

Christy Headlee

Alex Garrison

Christy Headlee, IIDA, LEED AP and Alex Garrison, AIA were promoted to design director. Gensler design directorsare thought leaders and stewardsfor design excellence; they are responsible for overall design quality of their projects and advancing the Gensler design culture. Christy Headlee is an interior designer with 10+ years of experience. She leads design efforts with intention and bold creativity. She is collaborative, passionate about inspiring and empowering others and is an inclusive leader who mentors and inspires others to explore their own creativity. Alex Garrison is an architect with 10+ years of experience. He is an award-winning designer who brings a strong conceptual approach to every design opportunity. A firm believer in always being curious, he leads project teams in the tireless pursuit of innovative design solutions.

Dunton Commercial Announces Two New Hires

Brett Welker

Caleb Krumsieg

Dunton Commercial, a Denver-based commercial property management and investment company has hired Brett Welker as the new director of property management and Caleb Krumsieg as the new director of Leasing.

Welker brings tremendous experience and leadership to our property management team, as well as asset management, acquisitions analysis and due diligence to our investment side of the business. He has achieved the designations of RPA (Real Property Administrator, BOMA) and CPM (Certified Property Manager, IREM).Prior to Dunton, Welker spent 21 years with Lowe, a commercial real estate investment company, most recently as vice president.

Krumsiegs focus at Dunton is to maintain high occupancy levels within the portfolio by leveraging Duntons technology and implementing a highly pro-active leasing strategy. He brings significant office and retail leasing experience to Dunton, most recently as a broker with Waveland Property Group in Wheaton, IL. Krumsieg has a B.A. in Business and Economics from Wheaton College.

Follow this link:
Movers and Shakers Week Ending 2.28.20 - milehighcre.com

Posted in David Sinclair | Comments Off on Movers and Shakers Week Ending 2.28.20 – milehighcre.com

Anti-Aging Researcher David Sinclair Takes Metformin, NMN …

David Sinclair is working on various anti-aging molecules. He was famous for discovering the anti-aging effect of resveratrol and sirtuins. David Sinclair was interviewed on the Joe Rogan show about antiaging.

In 2013, GlaxoSmithKline shutdown Sirtris (David Sinclairs company) about five years after spending $720 million to buy Sirtris.

David A. Sinclair, Ph.D., A.O. is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. Dr. Sinclair is co-founder of several biotechnology companies (Sirtris, Ovascience, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others. He is also co-founder and co-chief editor of the journal Aging.

Life Biosciences was co-founded in 2017 by David A. Sinclair, PhD, AO, a professor in the Department of Genetics at Harvard Medical School, and Tristan Edwards, an investment professional who developed its innovative company structure.

Sinclairs lab continues to work on resveratrol and analogs of it, as well as on mitochondria and NAD, all directed to understanding aging and how to prevent it.

His antiaging regimen is to activate pathways to improve the bodies defenses against aging.

He is testing NMN on human subjects. He describes NMN is fuel for sirtuins. NMN is related to NR. NR increases the levels of NAD. Sirtuins need NAD to work. We lose NAD as we age. We have half of the NAD by the time we are 50.

He takes a gram of NMN (Nicotinamide MonoNucleotide) and takes half a gram resveratrol in the morning with yogurt.

He is personally taking 1 gram of Metformin once a day at night.

He gives himself temperature treatments. He exposes himself to heat in a hot tub and then cold in a cold bath. The temperature treatments are again to activate the pathways to aging defense.

He also performs intermittent fasting. He skips meals and is a night time eater. He limits is sugar and carbs. He limits his eating of meat.

He is not taking Rapamycin because of concern over side-effects.

Anti-oxidants are a failure in the anti-aging field.

Metro Biotech makes a super-NAD booster which is called MIB-626. They hope to get it on the market to treat diseases in three years. It is in clinical trials for safety now.

Research has found the lining of blood vessels needs NAD.

SRT-2104 has had successful antiaging effects.

He gave the recent keynotepresentation atMonteJadeevent with a talk entitled the Future for You.He gave an annual update on molecular nanotechnology at Singularity University on nanotechnology, gave a TEDX talk on energy, and advises USC ASTE 527 (advanced space projects program). He has been interviewed for radio, professional organizations. podcasts and corporate events. He was recently interviewed by the radio program Steel on Steel on satellites and high altitude balloons that will track all movement in many parts of the USA.

He fundraises for various high impact technology companies and has worked in computer technology, insurance, healthcare and with corporate finance.

He has substantial familiarity with a broad range of breakthrough technologies like age reversal and antiaging, quantum computers, artificial intelligence, ocean tech, agtech, nuclear fission, advanced nuclear fission, space propulsion, satellites, imaging, molecular nanotechnology, biotechnology, medicine, blockchain, crypto and many other areas.

See original here:
Anti-Aging Researcher David Sinclair Takes Metformin, NMN ...

Posted in David Sinclair | Comments Off on Anti-Aging Researcher David Sinclair Takes Metformin, NMN …

Not fasting is killing us, but fasting can hurt us too. Here’s what to do. – Mashable

There's a switch inside every cell in your body. Flip it on and you're in growth mode. Your cells start dividing but in the process, they make a lot of junk like mis-folded proteins, which help create the conditions for our biggest diseases (including cardiovascular, Alzheimer's and the big C). Flip the switch off, though, and your cells literally take out the trash leaving them clean, renewed, effectively young.

We know how to flip the switch. The trick is figuring out when. Because leaving your body in cleanup mode for too long can also be extremely bad for your health, in the much shorter term. Doing so has been the cause of anxiety, misery and disorder, for decades. It's also known as starvation.

The delicate dance of food consumption is at the heart of The Switch, a new book about new body-energy science and how it can help us live longer. Author and research scientist James Clement studies people who reach the age of 110; Harvard's David Sinclair, who recently wrote a groundbreaking book on the end of aging, is his mentor. As Clement's book hit shelves, an unrelated study in Nature confirmed its premise: mTOR (your genetic "on" switch) cannot coexist with autophagy (trash removal), and that is "implicated in metabolic disorders, neuro-degeneration, cancer and aging," the study said.

In other words: We age faster, get sicker and harm our brains when we fill the hours we're awake with food, day in and day out. Organic beings need more of a break than just a good night's rest in order to properly take out the trash. We're the opposite of automobiles. We break down eventually unless we run out of fuel. (Glycogen, which is what the body converts food into, is our gas.)

These revelations shed a new spotlight on fasting, the main way to induce autophagy (you can also kickstart it with intense exercise on a mostly empty stomach). But this is where we run into problems, and not just because autophagy literally translates to "eating yourself." (It can be hard for scientists to explain that this is actually a good thing and that all living things do it, from simple yeast all the way up to primates; we were designed to work this way by millennia of feast and famine.)

The problem isn't the science, it's the culture. For most of history, fasting was locked into human lives at a steady, healthy pace in some form of ritual, religious or otherwise. But in the modern world, we make our own rituals, and they easily shade into obsessions. This happens a lot with new diets: We get the zeal of the convert. We bore our friends to death with the particulars. And we take it too far, which in the case of fasting can be dangerous.

In a column published this week, the New York Times' veteran health columnist Jane Brody came around to the value of intermittent fasting. But she sounded a personal note of caution: "For people with a known or hidden tendency to develop an eating disorder, fasting can be the perfect trigger, which I discovered in my early 20s. In trying to control my weight, I consumed little or nothing all day, but once I ate in the evening, I couldnt stop and ended up with a binge eating disorder."

Something similar, at least to the first part of that story, seems to have happened to Twitter CEO Jack Dorsey. Last year Dorsey boasted about fasting for 22 hours, eating just one meal at dinnertime, and skipping food for the whole damn weekend. "I felt like I was hallucinating," he enthused, boasting of his increased focus and euphoria.

But as many withering articles pointed out, Dorsey's words would have triggered concern if they came from the mouth of a teenage girl since focus and euphoria can also be early signs of anorexia and bulimia. Clearly there is a tangled set of gendered assumptions at play here. "Its both remarkable and depressing to watch Jack Dorsey blithely describe a diet that would put any woman or any non-wealthy man into the penalty box of public opinion," wrote Washington Post columnist Monica Hesse.

That's not what The Switch is about. Clement doesn't endorse Dorsey's extreme approach, since the research shows benefits diminish after 16 hours of fasting. "I have friends who are bulimic, I know how serious a problem it is," he said when I raised the issue. "The kind of fasting that I'm talking about is just making sure your mTOR and autophagy are in balance."

Indeed, The Switch is a very balanced book, with plenty of nuanced suggestions for how you can make your food situation just a little bit better without making too many radical changes. (That probably explains why it hasn't taken off on the diet book media circuit, which tends to favor rules that are extreme, unusual, and headline-friendly.)

Here's a breakdown of Clement's advice.

Like most medicine, the mTOR switch is good for you if used at the correct dose, and poison at high doses. There's a reason it exists: It's your body's way of saying "times are good, let's grow muscle and fat!" Fat isn't inherently bad for you, either on your body or in your diet. Indeed, the good fats are what Clement suggests we consume the most fish, avocados, plant-based oils and nuts, macadamias especially alongside regular greens, most legumes and a little fruit.

If you're cutting down the amount of time you eat, then the content of your meals matters more. Clement himself gets good results from a meatless version of the ketogenic diet, which he says makes him less hungry but he doesn't rule out other diets that focus on good fat and fiber.

At the very least, be sure to avoid the stuff that spikes blood sugar. It will make you too hungry too soon, which will make autophagy impossible. You didn't think this whole Switch thing was going to give you permission to snarf on soda and hot dogs, did you?

Well, it does, actually just very occasionally.

Clement brings a lot of science on protein to the table, and the bad news is you're probably eating way more of it than you think you need. Animal protein flips the mTOR switch into high gear (which is why Clement is into mostly vegan keto). Sadly, so does regular dairy, and as a milk fan I found the new studies on this particularly hard reading.

But it makes evolutionary sense. Cow milk is designed to make calves grow many sizes in a short space of time, and the way you do that is by activating the mTOR pathway. So it's hard to switch into autophagy if you're chugging milk all the time. (Non-cow milks and cheeses seem to be fine, mTOR-wise.)

Which isn't to say you can't have meat and milk at all. This isn't one of those fundamentally restrictive diets we always break. Clement suggests dividing the week or month or year into growth and fasting phases. You might decide to eat as much as you want for three months of the year (which takes care of the holidays problem), say, or try doing the fasting thing for five days a month.

Whichever way you do it, the sweet spot seems to put you in growth mode around 20 percent of the time. But that's not a hard and fast number, because again, this isn't one-size-fits-all. (It certainly doesn't apply to kids, who need to grow more like calves.) I told Clement that after reading the book I was thinking of only allowing myself meat or milk on the weekends; he enthusiastically endorsed the idea.

Ready to turn on autophagy for its disease-fighting benefits? Ready to avoid doing it too much? Ready to eat more nutritious food when you break your fast? Then it's time to figure out how long you want to fast for and you'll be surprised about how little time it takes to see the effects.

The math varies from human to human, but "you only have about six to 10 hours worth of glycogen stored in your body at any given time," says Clement. "So you can actually burn through those overnight if you didn't load up with carbs in your evening meal or 11 o'clock snacks."

That provides one particularly effortless way to fast for those of us who don't wake up hungry (and if you're eating the right stuff, you generally won't). Let's say you ate your last bite at 9 p.m. and wake up at 7 a.m. Congratulations, you're already out of glycogen and in autophagy! Now the question is: how long is it comfortable for you to stay foodless, bearing in mind you don't want to go past a total of 16 hours? (In this example, that would be 1 p.m.)

You'll definitely want to hydrate immediately, of course: Sleep literally shrivels your brain. You might want to drink some coffee, which enhances autophagy (the all-time Guinness World Record oldest human, Jeanne Calment of France, took no breakfast but coffee, and died at 122). If you can stand to do so, this would be a great time to work out. Exercise seems to act like an autophagy power up; one study suggests working up a sweat might boost our cells' trash-cleaning effectiveness all the way up to the 80-minute mark.

So if you went from 9 p.m. to 1 p.m., or whatever 16-hour period suits your schedule (7 p.m. to 11 a.m. seems to be a popular one for fasters who don't make late dinner reservations, and it is easily remembered as "7-11"), then congratulations. You just did the maximally beneficial fast. Take that, Jack Dorsey.

But if you didn't? No sweat. If you only made it until 10 a.m., or 8 a.m. before needing food, your entire body still got a boost of cleanup time. And if you needed an immediate breakfast, that's fine too. Fasting doesn't have to happen every day; in fact it's imperative that it doesn't. Every morning is an opportunity to listen to your body and see if it's ready for a quick restorative food break.

Everyone who's ever tried to diet knows the terrible guilt that comes after grabbing obviously bad food, Don't stress over it, says Clement. Don't be maniacal. The whole point is to be in balance. We all need mTOR-boosting feasts from time to time. "It's fine to have one pepperoni pizza on a Sunday, or whatever," he says. So long as you're eating well most of the time and fasting every now and again, you'll see positive effects.

And if you can't fast at all and can't stop snacking? No worries, just change what you're eating. "If you switch over to snacking on either very low glycemic veggies like broccoli tops or carrots, or nuts, then you're not going to be replenishing your glycogen stores," Clement says. Stick a small bowl of almonds and blueberries in the kitchen and you'll be surprised, over time, at how little it takes to satisfy supposedly giant cravings.

That was what I learned, not from Clement's book, but from David Sinclair's. The Harvard geneticist and Clement mentor doesn't focus so much on lengthy fasts, although he takes a number of fast-mimicking supplements. His dieting approach is to simply eat less, to "flip a switch in your head that allows you to be OK with being a little hungry." For some of us, such small moves may be more effective than going all-out on a new diet.

If youd like to talk to someone about your eating behaviors, call the National Eating Disorder Associations helpline at 800-931-2237. You can also text NEDA to 741-741 to be connected with a trained volunteer at the Crisis Text Line or visit NEDA's website for more information.

Read this article:
Not fasting is killing us, but fasting can hurt us too. Here's what to do. - Mashable

Posted in David Sinclair | Comments Off on Not fasting is killing us, but fasting can hurt us too. Here’s what to do. – Mashable

Lifespan: The New Science Behind Anti-Aging and Longevity that Can Help You Live to 100 – Thrive Global

Is aging a disease? David Sinclair, PhD, a professor of genetics at Harvard Medical School one of the worlds top experts on aging and longevity, thinks so.

His new book Lifespan: Why We Ageand Why We Dont Have To covers the latest research on longevity and anti-aging therapies. I was excited to read this book after listening to Sinclair on a podcast.

Sinclair believes that aging is a disease one that is treatable within our lifetimes. According to Sinclair, there is a singular reason why we age: A loss of information. The most important loss occursin the epigenome, the expression of genetic code that instructs newly divided cells what they should be.

Aging is like the accumulation of scratches on a DVD so the information can no longer be read correctly. Every time theres a radical adjustment to the epigenome, e.g. after DNA damage from the sun, a cells identity is changed. This loss of epigenetic information, Sinclair proposes, is why we age.

Scientists have discovered longevity genes that have shown the ability to extend lifespan in many organisms. These include sirtuins, rapamycin (mTOR), and AMPK.

There are natural ways to activate these longevity genes: High intensity exercise, intermittent fasting, low-protein diets, and exposure to hot and cold temperatures. These stressors, or hormesis, turn on genes that prompt the rest of the system to survive a little longer.

Researchers are studying molecules that activate longevity genes rapamycin, metformin, resveratrol and NAD boosters. Resveratrol is a natural molecule found in red wine that activates sirtuins and has increased lifespan in mice by 20 percent. NAD supplementation has been shown to restore fertility in mice that have gone through mousopause.

Sinclair believes these innovations will let us live longer and have less disease. He predicts that humans could live to 150 years of age in the near future, with average life expectancy rising from around 80 now to 110 or higher.

The best ways to activate your longevity genes: Be hungry more often skip breakfast, fast periodically for longer periods, get lean Avoid excessive carbs (sugar, pasta, breads) and processed oils and foods in general Do resistance training lift weights, build muscle Expose your body to hot, cold, and other stressors regularly.

See the rest here:
Lifespan: The New Science Behind Anti-Aging and Longevity that Can Help You Live to 100 - Thrive Global

Posted in David Sinclair | Comments Off on Lifespan: The New Science Behind Anti-Aging and Longevity that Can Help You Live to 100 – Thrive Global