Category Archives: Biotechnology

Press release

Cambridge, MA U.S.A. (September 26, 2022) Allarity Therapeutics, Inc. (Nasdaq: ALLR) (Allarity or the Company), a clinical-stage pharmaceutical company developing novel oncology therapeutics together with drug-specific DRP companion diagnostics for personalized cancer care, today announced the appointment of Jerry McLaughlin as a new member of its Board of Directors, effective October 1, 2022.

Mr. McLaughlin is a highly accomplished biotechnology executive with extensive experience in financing, drug development, licensing, commercialization, and product lifecycle management. Mr. McLaughlin is expected to serve on the compensation, and audit committees as an independent director.

I am delighted that Jerry has chosen to join Allaritys board at this crucial time in our evolution, said Dr. Duncan Moore, Allaritys Chairman of the Board. His operational experience in clinical stage therapeutic development and capital markets acumen will be of great value as we continue to implement the Companys combination therapy-focused strategy.

Mr. McLaughlin said: I firmly believe Allarity Therapeutics is in a unique position to become a leader within the personalized medicine space by developing novel combination oncology therapies together with the Companys unique DRP companion diagnostics. Allaritys recent strategic shift is aligned with the ongoing patient and market realities in oncology, as we continue to see substantially higher patient benefits with combination therapies. I look forward to supporting the CEO, Jim Cullem, and the rest of the Allarity team in unlocking both the clinical and commercial potential of this strategy.

Mr. McLaughlin has three decades of experience in leading operational and executive management roles. He made key contributions to significant life science milestones, including product launches, acquisitions, and financings. He is currently serving as CEO and Board Member of Life Biosciences, LLC, a development-stage biopharmaceutical company advancing therapeutics for patients with neurological and psychiatric diseases. Prior to serving in this role, he was President, CEO, and Member of the Board of Directors at Neos Therapeutics (acquired by Aytu BioScience.) Before joining Neos Therapeutics, he served as President, CEO, and Member of the Board of Directors at AgeneBio, Inc. Earlier in his career, he held corporate leadership roles at NuPathe, Inc., Endo Pharmaceuticals Inc., and Merck & Co., Inc. He received his B.A. from Dickinson College and his MBA from Villanova University in Pennsylvania.

About Allarity Therapeutics

Allarity Therapeutics, Inc. (Nasdaq: ALLR) develops drugs for personalized treatment of cancer guided by its proprietary and highly validated companion diagnostic technology, the DRP platform. The Company has a mature portfolio of three drug candidates: stenoparib, a PARP inhibitor in Phase 2 development for ovarian cancer; dovitinib, a post-Phase 3 pan-tyrosine kinase inhibitor; and the European rights to IXEMPRA (Ixabepilone), a microtubule inhibitor approved in the U.S. and marketed by R-PHARM U.S. for the treatment of second-line metastatic breast cancer, currently in Phase 2 development in Europe for the same indication. Additionally, the Company has rights in two secondary assets: 2X-111, a liposomal formulation of doxorubicin in Phase 2 development for metastatic breast cancer and/or glioblastoma multiforme (GBM), which is the subject of discussions for a restructured out-license to Smerud Medical Research International AS; and LiPlaCis, a liposomal formulation of cisplatin and its accompanying DRP, being developed via a partnership with Chosa ApS, an affiliate of Smerud Medical Research International, for late-stage metastatic breast cancer. The Company is headquartered in the United States and maintains an R&D facility in Hoersholm, Denmark. For more information, please visit the Companys website at http://www.Allarity.com.

About the Drug Response Predictor DRP Companion Diagnostic

Allarity uses its drug-specific DRP to select those patients who, by the genetic signature of their cancer, are found to have a high likelihood of responding to the specific drug. By screening patients before treatment, and only treating those patients with a sufficiently high DRP score, the therapeutic response rate can be significantly increased. The DRP method builds on the comparison of sensitive vs. resistant human cancer cell lines, including transcriptomic information from cell lines combined with clinical tumor biology filters and prior clinical trial outcomes. DRP is based on messenger RNA from patient biopsies. The DRP platform has proven its ability to provide a statistically significant prediction of the clinical outcome from drug treatment in cancer patients in 37 out of 47 clinical studies that were examined (both retrospective and prospective), including ongoing, prospective Phase 2 trials of Stenoparib and IXEMPRA. The DRP platform, which can be used in all cancer types and is patented for more than 70 anti-cancer drugs, has been extensively published in peer reviewed literature.

Follow Allarity on Social Media

Facebook: https://www.facebook.com/AllarityTx/ LinkedIn: https://www.linkedin.com/company/allaritytx/ Twitter: https://twitter.com/allaritytx

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements provide Allaritys current expectations or forecasts of future events. The words anticipates, believe, continue, could, estimate, expect, intends, may, might, plan, possible, potential, predicts, project, should, would and similar expressions may identify forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include, but are not limited to, statements related to clinical and commercial potential due to the Company advancing dovitinib in combination with another therapeutic candidate or other approved drug, any statements related to ongoing clinical trials for stenoparib as a monotherapy or in combination with another therapeutic candidate for the treatment of advanced ovarian cancer, or ongoing clinical trials (in Europe) for IXEMPRA for the treatment of metastatic breast cancer, and statements relating to the effectiveness of the Companys DRP companion diagnostics platform in predicting whether a particular patient is likely to respond to a specific drug. Any forward-looking statements in this press release are based on managements current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. These risks and uncertainties include, but are not limited to,the risk that results of a clinical study do not necessarily predict final results and that one or more of the clinical outcomes may materially change following more comprehensive reviews of the data, and as more patient data become available, the risk that results of a clinical study are subject to interpretation and additional analyses may be needed and/or may contradict such results, the receipt of regulatory approval for dovitinib or any of our other therapeutic candidates or, if approved, the successful commercialization of such products, the risk of cessation or delay of any of the ongoing or planned clinical trials and/or our development of our product candidates, the risk that the results of previously conducted studies will not be repeated or observed in ongoing or future studies involving our therapeutic candidates, and the risk that the current COVID-19 pandemic will impact the Companys current and future clinical trials and the timing of the Companys preclinical studies and other operations. For a discussion of other risks and uncertainties, and other important factors, any of which could cause our actual results to differ from those contained in the forward-looking statements, see the section entitled Risk Factors in our Form S-1 registration statementon file with theSecurities and Exchange Commission, available at the Securities and Exchange Commissions website atwww.sec.gov, and as well as discussions of potential risks, uncertainties and other important factors in the Companys subsequent filings with theSecurities and Exchange Commission. All information in this press release is as of the date of the release, and the Company undertakes no duty to update this information unless required by law.

###

Company Contact:

Thomas JensenSenior V.P. of Investor Relationsinvestorrelations@allarity.com

Investor Relations:

Chuck PadalaLifeSci Advisors+1(646) 627-8390chuck@lifesciadvisors.comU.S. Media Contact:

Mike Beyer Sam Brown, Inc. +1 (312) 961-2502 mikebeyer@sambrown.com

EU Media Contact:

Thomas PedersenCarrotize PR & Communications +45 6062 9390tsp@carrotize.com

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Allarity Therapeutics Appoints Seasoned Biotechnology Executive Jerry McLaughlin to Board of Directors - GlobeNewswire

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The global bio-economy is growing at an incredible pace, with plenty of opportunity for investors. The biotech industry in general, and biotech stocks specifically, provide a lot of potential for long-term returns. Biotechnology is the application of biological principles to create new products and services. It has many applications, from agricultural uses to medical research and drug development. As a result, the biotechnology sector has grown strongly as other industries adopt its technologies and invest in related ventures and partnerships.Investors looking to capitalize on this growth need to understand which companies are leading the way. Fortunately, there are several great biotechnology stocks that can offer excellent returns in the coming years. Here are some of the top opportunities currently available:

Global Blood Therapeutics (GBT) is an emerging biotechnology company focused on creating therapies for rare blood diseases.GBTs lead product, Prophage, is a gene therapy designed to treat patients with beta-thalassemia, a rare inherited blood disorder.drug has been granted Orphan Drug Designation by the FDA and designation as a Breakthrough Therapy from the FDAs Oncology Drug Review Committee.GBT has also partnered with Galapagos NV, one of the top gene-therapy companies in the world. The company has a Phase 3 development program for Prophage, with a goal to complete registration in the next few years. With a potential blockbuster drug on the table, GBT has the potential to grow very quickly.

BridgeBio Pharma (BBIO) is a clinical-stage biopharmaceutical company focused on bringing new therapies to patients suffering from rare diseases.BBIO has a robust product pipeline, with several therapies in Phase 1 and 2 clinical trials. The company is also in the pre-clinical development stages of several promising new therapies. BBIOs main product candidates are focused on iron-related disorders, including an iron chelating agent for patients with rare blood diseases.BBIO has partnered with some of the largest companies in the world, including The Medicines Company, Celgene, and Bayer.BBIOs therapies are currently in Phase 2 development and are expected to advance into Phase 3 in the next few years. When these drugs are approved, BBIO will be poised for growth.

SIGA Technologies (SIGA) is a biopharmaceutical company focused on creating vaccines and medicines for infectious diseases.SIGA has a robust product pipeline focused on viral diseases, including respiratory and viral hemorrhagic fever diseases. The company is currently investing in three main products.First is a universal flu vaccine designed to address issues with current flu vaccines. SIGAs universal flu vaccine is administered as a nasal spray, has no adjuvant, and is designed to provide constant immunity to the most common flu strains.Second is an Ebola vaccine designed to treat patients infected with the Ebola virus. The vaccine has been in development since 2003, when the Ebola outbreak in Africa began.Third is a therapeutic vaccine designed to treat dengue fever. The vaccine has completed Phase 1/2 trials and is expected to advance into Phase 3 trials in the next few years.

Ninety (NOVT) is a biotechnology company focused on creating therapies for the eye.NOVT is currently developing a first-in-kind therapy called a corneal scarring therapy that could replace corneal transplants in some patients.The company is expected to advance this product into Phase 3 trials in the next few years. Once the treatment is approved, it could become a huge product for NOVT.While the companys main product remains in development, it is also investing in other eye-related therapies. NOVT has a partnership with Galapagos NV to develop gene therapies for retinal diseases. The company is also developing a novel combination therapy for glaucoma.

Biotechnology is a growing industry that is expected to continue to see strong growth. The sector is also expected to see some strong mergers and acquisitions, providing another avenue for growth.Investors looking for growth in the biotechnology industry can consider investing in any of the top biotechnology stocks above. These companies are all poised for growth over the next several years, and could offer excellent returns for investors.

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The global economy is growing incredibly, with plenty of opportunities for investors. The biotech industry, in general, and biotech stocks, provide a lot of potential for long-term returns. Biotechnology is the application of biological principles to create new products and services. It has many applications, from agricultural uses to medical research and drug development. As a result, biotechnology has grown strongly as other industries adopt its technologies and invest in related ventures and partnerships. Investors looking to capitalize on this growth need to understand which companies are leading the way. Fortunately, several great biotechnology stocks can offer excellent returns in the coming years. Here are some of the top opportunities currently available:

Global Blood Therapeutics (GBT) is an emerging biotechnology company focused on creating therapies for rare blood diseases.GBTs lead product, Prophage, is a gene therapy designed to treat patients with beta-thalassemia, a rare inherited blood disorder. The drug has been granted Orphan Drug Designation by the FDA and designated as a Breakthrough Therapy by the FDAs Oncology Drug Review Committee.GBT has also partnered with Galapagos NV, one of the top gene-therapy companies in the world. In addition, the company has a Phase 3 development program for Prophage, to complete registration in the next few years. With a potential blockbuster drug on the table, GBT has the potential to grow very quickly.

BridgeBio Pharma (BBIO) is a clinical-stage biopharmaceutical company focused on bringing new therapies to patients suffering from rare diseases.BBIO has a robust product pipeline, with several therapies in Phase 1 and 2 clinical trials. The company is also in the pre-clinical development stages of several promising new therapies. BBIOs main product candidates are focused on iron-related disorders, including an iron chelating agent for patients with rare blood diseases.BBIO has partnered with some of the largest companies in the world, including The Medicines Company, Celgene, and Bayer.BBIOs therapies are currently in Phase 2 development and are expected to advance into Phase 3 in the next few years. When these drugs are approved, BBIO will be poised for growth.

SIGA Technologies (SIGA) is a biopharmaceutical company focused on creating vaccines and medicines for infectious diseases.SIGAs robust product pipeline focused on viral diseases, including respiratory and viral hemorrhagic fever. The company is currently investing in three main products:

The vaccine has completed Phase 1/2 trials and is expected to advance into Phase 3 trials in the next few years.

Ninety (NOVT) is a biotechnology company focused on creating therapies for the eye.NOVT is currently developing a first-in-kind therapy called corneal scarring therapy that could replace corneal transplants in some patients. The company is expected to advance this product into Phase 3 trials in the next few years. Once approved, the treatment could become a huge product for NOVT. While the companys main product remains developing, it is also investing in other eye-related therapies. For example, NOVT partnered with Galapagos NV to develop gene therapies for retinal diseases. In addition, the company is also developing a novel combination therapy for glaucoma.

Biotechnology is a growing industry that is expected to continue to see strong growth. The sector is also expected to see strong mergers and acquisitions, providing another avenue for growth. Investors looking for growth in the biotechnology industry can consider investing in any of the top biotechnology stocks above. These companies are poised for growth over the next several years and could offer excellent returns for investors.

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The Best Biotechnology Stocks to Invest in Right Now - Best Stocks

China has very small farms; there hasnt been a lot of infrastructure put in place in terms of knowledge or solid assets. Now Syngenta is enabling them with agronomists and digital infrastructure.

When it comes to Beijings technological ambitions, high profile hardware like semiconductors and electric vehicles tend to dominate global headlines. But in China, where almost 20 percent of the global population lives on 8.5 percent of the worlds arable land, finding innovative ways to reap more food from every hectare of seeds sown has long been one of the governments highest priorities.

Chinese agriculture and food demand is in inherent conflict, says Wendong Zhang, an assistant professor at Cornell Universitys Dyson School of Applied Economics and Management and a specialist in Chinas agricultural development. China wont be able to have more land. They wont be able to have better quality soil. The thing they can control is technology.

Beijings realization that technology would be key to increasing its food self-sufficiency is what made Syngenta such a valuable target for ChemChina. Syngenta, after all, is the world-leader in crop protection products and globally the number three producer of seeds, including selectively-bred hybrids and genetically modified seeds. Alongside rivals like Germanys Bayer and Americas Corteva (formerly DowDupont), the company is pushing the boundaries of seed genomics using CRISPR-Cas9, a tool that allows researchers to tweak the genetics of living organisms.

Emboldened by its ownership of Syngenta, China seems to be crossing the rubicon when it comes to high-tech agriculture. Officials are now calling cutting-edge seeds agriculture microchips, according to Chinese state media.

And safety approvals for GM seeds appear to be speeding up: in early 2022, Beijings Ministry of Agriculture and Rural Affairs (MARA) granted safety certificates to three Syngenta GM corn seeds as well as a seed from the domestic firm Hangzhou Ruifeng Bio-Tech Company and several others from Chinese universities. In June, MARA also released guidelines, for the first time, that could pave the way for companies to begin commercial planting of GM products.

And with its high-profile Shanghai listing, Syngenta might help the Chinese government out of a dilemma of its own making: convincing the general public that GMOs are safe. At the very least, the company cant be viewed as a trojan horse for U.S. bioweapons. Syngentas MAP program has even introduced QR codes on food packaging so consumers can scan their food and see a photo of the Chinese farmer who grew it.

To help itself out of its GMO bind, Beijing is also positioning its efforts in direct gene editing as a kind of technological leapfrogging these newer engineering methods do not require the introduction of foreign DNA, unlike todays genetic modification, in which bacteria from one organism is transplanted into another ( la the Bt genes added into the corn genome). As [Shane] Thomas, the analyst, notes, the industry as a whole is moving towards this more precise kind of genetic tweaking.

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China's Syngenta pushes the edge: Can technology-driven agriculture promote a new view of sustainable farming to a world still wary of biotechnology?...

England is in crisis. They lost a beloved figurehead this month but for decades prior were losing scientific ground. If you look for the home of the modern organic food and anti-vaccine movements, you find their nexus in 1990s England.

The primary royal behind those beliefs is now King Charles III.

In order to manage the $28 billion he inherits (tax-free, paying taxes only applies to peasants in England)(1) he will have to give his $1.5 billion estate to his son, the new Prince of Wales, William (also tax free) but the Prince is not only taking over during a time when Brits are wondering why they still care about a throne that hasnt been relevant in hundreds of years, he is taking over at a time when being anti-science is no longer fashionable for progressive elites.

Though it was recently the darling of the intelligentsia, and Prince Charles longed to belong in that circle, anti-vaccine sentiments have become proletariat since COVID-19. The war on science when it comes to food harms a lot more people worldwide each year than the pandemic did. Hundreds of thousands of kids could stop going blind each year with Golden Rice but elites like King Charles III give money to groups that block its implementation.

Prince William could start to gain back some credibility for the family by jettisoning the organic food fetish of his father. Organic food, like the anti-vaccine movement, is a relic of 1990s England. Dr. Andrew Wakefield set off the modern anti-vaccine craze the same way that English environmental activists set off the Frankenfood one. Now supplements, wellness, and organic are all giant businesses based on exploitation of famous names who wanted to impress their elite friends

The world should have passed the anti-vaccine and anti-food movement by but they persist in large part because of the new British monarch and his quasi-American royalty of American Democrats counterpart, Robert F. Kennedy, Jr.(2)

Its easy to embrace science, especially in light of their history making changes when it was needed. They changed their name to Windsor from Saxe-Coburg and Gotha during World War I to help commoners forget the British royal family is German during a time that Germany was shooting at English men in Europe. Given that public relations success, they can certainly change their tune when it comes to science.

Perhaps due to an infusion of new blood outside the shockingly limited pool drawn from during the 19th and 20th centuries, Prince William seems to be a more genetically gifted thinker than his father. He can show it by embracing the modern world, where food and medicine are embraced.(3)

He doesnt actually have to divest from the farm, that is just me getting attention in a title. It is enough if he acknowledges that having peasants toil for his carrots only using specially labeled toxic pesticides is a pastime for the rich, and not a way to feed the world.

(1) The same way California Governor Gavin Newsom doesnt want people who make over $2 million each year to pay higher taxes to subsidize the electric cars the Governor insists Uber drivers need to buy. High taxes are for the middle class and the poor, not the donors he will need in order to fail running for President in 2024.

(2) Nothing looks more hypocritical than people on the left in England and the US suddenly endorsing vaccines when just two years ago they opposed them. It instead reeks of politics, and politics need to be a no-no for the new generation of British royals, lest they be relegated to the name recognition of the Queen of the Netherlands, whoever that is.

(3) and not just engage in publicity stunts about energy costs that are squarely the blame of the government his father now seeks to lead.

Hank Campbell founded Science 2.0 in 2006, and writes for USA Today, Wall Street Journal, CNN, and more. His first book,Science Left Behind,was the #1 bestseller on Amazon for environmental policy books. Follow Hank on Twitter@HankCampbell

A version of this article was originally posted atScience 2.0and is reposted here with permission. Science 2.0 can be found on Twitter@science2_0

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Viewpoint: Will King Charles abandon his kooky ideas about agriculture and help accelerate Britain's embrace of sustainable biotechnology tools? -...

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Fullerenes Liquid Crystals Liposomes Nanoshells Quantum dots Superparamagnetic nanoparticles

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Nanoparticles in Biotechnology and Pharmaceuticals Market Size And Forecast To 2022 |Roche, GE Healthcare, Merck, Novartis, AMAG Pharmaceuticals The...

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Tribulus Terrestris Extract Market Demand With Future Forecast Green Labs, BioTae, Nutra Green Biotechnology, JIAHERB The Colby Echo News - The...