Category Archives: BioEngineering

Indian Institute of Technology Jodhpur inaugurated AyurTech, the Center of Excellence (CoE) sponsored by the Ministry of Ayush on 12th May 2023. The CoE AyurTech is part of the Centre of Excellence in Artificial Intelligence (AI) based Precision Healthcare at the school of Artificial Intelligence and Data Science (AIDE) at IIT Jodhpur. The aim of this center is to establish an AI-driven integrative framework for population and individual risk stratification and early actionable precision health interventions.

The AyurTech CoE was inaugurated by the Chief Guest, Vaidya Rajesh Kotecha, Honble Secretary, Ministry of Ayush, Government of India, and Prof. Santanu Chaudhury, Director, IIT Jodhpur in the presence of faculty and staff of the institute. The Centre for AyurTech is being proposed as the first-of-its-kind initiative in the precision health and medicine space that would combine Electronics, Digital health and AI and multi-omics technologies for realising Evidence-based Ayurveda solutions in a transdisciplinary framework.

Speaking during the inauguration event, Vaidya Rajesh Kotecha, Honble Secretary, Ministry of Ayush, Government of India, said, I am honored to inaugurate the AyurTech Center of Excellence sponsored by the Ministry of Ayush, Government of India, at IIT Jodhpur. Ayurveda Vigyaan is the future of healthcare system. I congratulate IIT Jodhpur for taking this initiative and hope this will help researchers in developing indigenous technologies. I am sure in the upcoming years this center will translate various research projects into successful outcomes for the betterment of the public at large.

A built-up space of approximately 3760 sq.ft. for an AyurTech facility for Phenotyping, Molecular Biology, Chemistry and Device development fabrication and characterization area has been provided by IIT Jodhpur. This space for technological immersion will enable capacity building in different domains of Ayurveda, increase employability in transdisciplinary domain, provide innovation and entrepreneurship opportunities and help in trans-disciplinary research programs.

Speaking about AyurTech CoE, Prof. Santanu Chaudhury, Director, IIT Jodhpur, said, I thank Vaidya Rajesh Kotecha ji for gracing the inauguration event with his esteemed presence. The collaboration of Ayurveda and Technology can bring a new medical field of integrated medicines into the mainstream. The philosophy of this center is to work on individual-centric medicine at an affordable cost using artificial intelligence and data science. The Ayurtech CoE will prioritize research on how to make sure people do not get a disease, than, treating a disease.

Key research areas that the centre will focus are as follows:

Digital devices integrated with IoT, AI and computer vision for rapid, objective, and accurate assessments of Ayurveda parameters and tailoring interventions

Blockchain powered highly secure and privacy preserving smart phone platforms, for large scale Ayurveda parameter screening, health, and intervention monitoring

Laboratory and Point-of-Care (PoC) deployable sensors/ devices, systems and frameworks will be developed for Ayurveda drug standardization

Open-source platforms of drug-disease networks using a compendium of molecular signatures of drugs, medicinal plants and Ayurveda based formulations for discoveries, poly-pharmacology and repurposing

Ontological frameworks based on Natural Language Processing for integration of knowledge base of Ayurveda with contemporary terminologies and description

Implementation of integrative medicine in different clinical settings

Investigators from the Department of Bioscience and Bioengineering, Department of Computer Science and Engineering, Department of Electrical Engineering and Department of Chemistry at IIT Jodhpur, will collaborate with doctors at Dr. Sarvepalli Radhakrishnan Rajasthan Ayurved University, University College of Ayurved, and AIIMS Jodhpur as part of the CoE AyurTech.

Dr. Mitali Mukerji, Professor, Department of Bioscience and Bioengineering, IIT Jodhpur and Dr. Ajay Agarwal, Professor, Department of Electrical Engineering, IIT Jodhpur, are jointly coordinating the project. Additionally, accomplished faculties from different departments of IIT Jodhpur including the School of Artificial Intelligence and Data science (AIDE) who have expertise in the field will be available for the project.

Excerpt from:
IIT Jodhpur inaugurates AyurTech, the Center of Excellence (CoE ... - NE India Broadcast

WEST LAFAYETTE, Ind. Purdue University began its annual spring rite Friday morning (May 12) with the first of nine commencement ceremonies that will take place throughout the weekend. All ceremonies are in Elliott Hall of Music on Purdues campus.

Purdues 2023 spring class had 9,776 candidates eligible for graduation. The list includes 7,398 undergraduates, 1,750 master's candidates, 390 doctoral candidates and 238 professional degree-seekers.

Mung Chiang, who in January became Purdues 13th president, is addressing graduates for the first time at this years spring ceremonies.

Kathleen Howell,Purdues Hsu Lo Distinguished Professor of Aeronautics and Astronautics, will provide the keynote for the graduate student ceremony at 7 p.m. Sunday (May 14). Howell has received national and international acclaim for her work in orbit mechanics, spacecraft dynamics and trajectory optimization. She has contributed to the success of multiple NASA missions, including Genesis, Artemis and Cassini, and was recognized with the Morrill Award in 2019, Purdues highest faculty honor.

Commencement division dates and times are as follow:

The ceremonies are being livestreamed from thePurdue News YouTubechannel and linked on the Purduecommencement website before each ceremony begins.

Honorary doctorates

Thomas Shelby, executive vice president of Peter Kiewit and Sons Inc. and president of Kiewit Energy Group, will receive an honorary doctorate from Purdue Polytechnic Institute during the Division VI ceremony.

During Shelbys tenure as president and board member of Kiewit Energy, the company has expanded its engineering and energy business from less than $100 million in 1991 to over $6 billion today. He led initiatives to open Kiewit Energy offices in Canada and Mexico and form engineering hubs in North America, growing the companys engineering capabilities from 100 employees in 2000 to almost 3,000 employees. Kiewit is the third largest engineering and construction company in North America, designing and building $13 billion of work annually and employing more than 40,000 people.

Shelby is a member of the National Academy of Construction, an honorary group of engineering and construction industry leaders. He is a member of the Purdue Polytechnic Advisory Council and a past Purdue Distinguished Alumni. Shelby earned a bachelors degree in construction management from Purdue in 1981 and his Master of Science and MBA from Arizona State University in 1989.

Student responders at each ceremony

Each undergraduate division feature a student responder:

Top student awards

Purdues Flora Roberts and G.A. Ross awards are the universitys most prestigious honors for two outstanding seniors.

Lara B. Chuppe of South Bend, Indiana, is the winner of the 2023 G.A. Ross Award. Chuppe graduates with a Bachelor of Science degree in computer science from the College of Science. She has had several leadership roles in Global House, a learning community in the John Martinson Honors College and has been recognized with Pillar Awards for community and global engagement in 2021 and 2022. Chuppe has been involved in College Mentors for Kids, Global Science Partners, English Language Learners In-Home Program and several volunteer tutoring programs. Chuppe also completed a summer internship with Advocates for Human Rights, where she worked directly on U.S. immigration policies for Afghan evacuees.

Frances Ann Fu OLeary of Claremont, California, is the winner of the 2023 Flora Roberts Award. OLeary graduates with a Bachelor of Science degree in computer science and mathematics from the College of Science. She has been a part of a U.S. Army-sponsored research group to build a self-correcting 3D printer and served as information technology lead on the Purdue Space Program High Altitude subteam. OLeary has held internships with SpaceX and Microsoft and served as an officer in several organizations, including the Purdue 3D Printing Club, Computer Science Womens Network and Purdue Space Program. OLeary has also served as a teaching assistant and has completed training to be a licensed pilot.

These awards are made possible through bequests from Flora Roberts, Purdue Class of 1887, and G.A. Ross, Purdue Class of 1916. Each recipient receives a $2,000 award and medallion and has their name permanently inscribed on the award marker on the Purdue Engineering Mall.

About Purdue University

Purdue University is a top public research institution developing practical solutions to todays toughest challenges. Ranked in each of the last five years as one of the 10 Most Innovative universities in the United States by U.S. News & World Report, Purdue delivers world-changing research and out-of-this-world discovery. Committed to hands-on and online, real-world learning, Purdue offers a transformative education to all. Committed to affordability and accessibility, Purdue has frozen tuition and most fees at 2012-13 levels, enabling more students than ever to graduate debt-free. See how Purdue never stops in the persistent pursuit of the next giant leap athttps://stories.purdue.edu.

Writer/Media contact:Ellie Acra,eacra@purdue.edu

Media contact: Jim Bush, jsbush@purdue.edu

Follow this link:
Small steps to giant leaps: Celebration of 2023 Purdue graduates ... - Purdue University

May 10, 2023 | Researchers in Sweden who previously introduced a hydrogel wound dressing constructed of nanocellulose that requires no changing have further improved on their innovation with the integration of a pH sensor to passively monitor for early signs of infection. In parallel, theyre working on antimicrobial substances based on lipopeptides that are showing potency against multiple types of bacteria, according to Daniel Aili, professor in the division of biophysics and bioengineering at Linkping University.

The agenda here is to transform wound care by creating efficiencies for caregivers and better outcomes for patients while reducing the unnecessary use of antibiotics. In a study published recently in Materials Today Bio (DOI: 10.1016/j.mtbio.2023.100574), the nanocomposites demonstrated excellent wound dressing properties and the sensor was shown to rapidly produce a naked-eye readout of wound pH. Infection typically results in a change in wound pH, which is indicated by a color shift in the dressing from yellow to blue. The elevated pH value in the wound can be detected long before common signs of infection such as pus, soreness, and redness.

The tight-knit nanocellulose prevents bacteria and other microbes from getting in, but allows gases and liquid through, Aili explains. S2Medical, a Swedish wound care company, invented the dressing and is enabling academic investigators to have direct contact with patients to better translate products to the clinic.

Detection and management of infection in chronic woundsthose that have not healed within six weeks to three months or are recurringis particularly important, as they are taking a heavy and growing toll on healthcare systems and patients the world over, he says. These hard-to-heal wounds represent about half of all costs in outpatient care.

Most people know someone who has a chronic wound, says Aili. It is way bigger than cancer when it comes to how many people are affected by wounds. In the U.S., between 3% and 4% of the population 65 and older have open wounds and many of them have underlying conditions such as diabetes and vascular disease. Prolonged hospital stays, and the required wound dressing changes, also exacerbate patient suffering.

The way chronic wounds are treated, which hasnt changed in any significant way for decades, is part of the problem, he says. The focus has been on managing wounds to ensure they dont get worse, rather than on healing them, which requires a holistic approach that includes improved wound diagnostic strategies.

Many different scientific fields have come together for the research underway at Linkping University, says Aili, which is being done in collaboration with colleagues from rebro and Lule Universities. These include molecular materials, nanotechnology, disaster and cardiovascular medicine.

Antibiotics are used extensively in wound care and the targeted pathogens typically are (or become) resistant to treatment, often with catastrophic consequences, Aili shares. Regular wound debridement, to remove dead tissue, is commonly done to prevent infection. Irrigation with antiseptics is also done to prevent or treat emerging infections.

Of course, the earlier you detect and treat an infection .. the better possibilities you have to reduce infection and get rid of it, says Aili. But to do so the conventional way requires a trip to the doctors office about every two days for a dressing change, and an assessment of the wound, which is both painful and inconvenient for patients. The dressing change process itself disturbs wound healing, and the risk of infection also increases every time the wound is exposed.

The nanocellulose-based dressings are essentially integrated into the tissue during the healing phase and spontaneously fall off with the scab, he continues, but this only works if you dont get an infection during this process. The new dressing is designed to stay in place during the entire healing process and report suspicions of infection. It doesnt break down because the body has no endogenous enzymes that degrade cellulose.

A dye known as bromothymol blue is used to make the wound dressing change color when the pH value exceeds 7. It gets loaded onto a silica material with nanometer-sized pores before being combined with the dressing material.

Biomarker-wise, the device is quite simple as instruments for measuring pH have been around for nearly a century. In fact, wound pH can in principle be measured using litmus paper strips at the same time dressings are being changed, Aili points out.

But even with optimized treatment, he adds, chronic wounds heal very slowlya median of more than 40 days, based on a previous case study. The pH-responsive nanocomposites can stay on as long as needed.

Wound care in general is an enormously complex field, Aili says. All wounds are unique, and should patients develop an infection despite seemingly perfect care, they are automatically at risk of it not healing. Physicians, understandably, also need evidence that a medical device has been properly evaluated according to regulatory guidelines before they adopt it in their clinical practice.

Among other projects underway are further development of the wound dressing from a different source of cellulose, reports Aili. Researchers have also synthesized a promising anti-microbial substance in the lab that they are currently working to integrate into the device but can be used on its own. The small, protein-like peptides have been lipidated with a tiny hydrophobic moiety to ramp up their potency, he says.

Regulatory obligations for bringing a medical device to market can take five to 10 years, Aili notes. The research team is currently testing all the components of its newfangled wound dressing, alone and in combination, with the first clinical trials expected to begin within the next two years.

Read the original:
Novel Wound Dressing Monitors For Infection In Real Time - Bio-IT World

They began training in the performance art last year as a way to engage young people in bioengineering projects and encourage them to pursue a career in science.

Workshops took place in the city and Bognor Regis with the Portsmouth Young Carers Centre, The Makers Guild, Making Theatre, and local secondary school students.

The aim was to promote the work being done at the universitys Centre for Enzyme Innovation (CEI), which is researching solutions to the problem of global plastic pollution.

Brooke Wain, second year PhD student, said: It has been striking to see the impact of bringing together science and the creative arts to explain some really complicated research. Exploring various creative techniques to describe our scientific research in a digestible and accessible way has not only been fun but has shown to be really effective!

The Puppets as Enzyme Engineers of the Imagination project was one of 23 to receive an Ingenious award by the Royal Academy of Engineering.

Senior lecturer in the school of art, design and performance at the University of Portsmouth, Dr Matt Smith, has led the workshops. He said: Our workshops have given researchers and engineers the confidence to better connect with the public. Not only have they learnt puppetry, but theyve also walked away with the communication and presentation skills needed to share their stories, passion, and expertise.

The showcase is at White Swan Studios, Portsmouth, on Tuesday, May 23, from 6-8pm. Free tickets here: eventbrite.co.uk.

See the article here:
Scientists learn puppetry to help showcase their work in fighting ... - Portsmouth News

Perfusion Bioreactor Market Report: 2023-2028

Perfusion Bioreactor Market (Newly published report) which covers Market Overview, Future Economic Impact, Competition by Manufacturers, Supply (Production), and Consumption Analysis

The market research report on the global Perfusion Bioreactor industry provides a comprehensive study of the various techniques and materials used in the production of Perfusion Bioreactor market products. Starting from industry chain analysis to cost structure analysis, the report analyzes multiple aspects, including the production and end-use segments of the Perfusion Bioreactor market products. The latest trends in the industry have been detailed in the report to measure their impact on the production of Perfusion Bioreactor market products.

Perfusion Bioreactor Market was valued at US$ 775 Million in 2022, and is projected to reach US$ 1249 Million by 2028, growing at a CAGR of 10% during the forecast period 2023-2028.

Get sample of this report @ https://www.marketresearchupdate.com/sample/410556

Results of the recent scientific undertakings towards the development of new Perfusion Bioreactor products have been studied. Nevertheless, the factors affecting the leading industry players to adopt synthetic sourcing of the market products have also been studied in this statistical surveying report. The conclusions provided in this report are of great value for the leading industry players. Every organization partaking in the global production of the Perfusion Bioreactor market products have been mentioned in this report, in order to study the insights on cost-effective manufacturing methods, competitive landscape, and new avenues for applications.

Leading key players in the Perfusion Bioreactor market are Sartorius AG, Thermo Fisher, GE Healthcare Life Sciences, Pall, Eppendorf AG, ZETA, 3D Biotek, Infors HT, Applikon Biotechnology, Bioengineering AG, PBS Biotech, Inc., Cell Culture Company, Zellwerk GmbH

Product Types:Small Scale (100 Liters)Mid-Scale (100 Liters to 1,000 Liters)Large Scale (>1,000 Liters)

On the Basis of Application:BiopharmaceuticalBiotechnologyOthers

Get Discount on Perfusion Bioreactor report @ https://www.marketresearchupdate.com/discount/410556

Regional Analysis For Perfusion BioreactorMarket

North America(the United States, Canada, and Mexico)Europe(Germany, France, UK, Russia, and Italy)Asia-Pacific(China, Japan, Korea, India, and Southeast Asia)South America(Brazil, Argentina, Colombia, etc.)The Middle East and Africa(Saudi Arabia, UAE, Egypt, Nigeria, and South Africa)

This report comes along with an added Excel data-sheet suite taking quantitative data from all numeric forecasts presented in the report.

Whats in the offering: The report provides in-depth knowledge about the utilization and adoption of Perfusion Bioreactor Industries in various applications, types, and regions/countries. Furthermore, the key stakeholders can ascertain the major trends, investments, drivers, vertical players initiatives, government pursuits towards the product acceptance in the upcoming years, and insights of commercial products present in the market.

Get Full Report @ https://www.marketresearchupdate.com/industry-growth/perfusion-bioreactor-market-size-410556

Lastly, the Perfusion Bioreactor Market study provides essential information about the major challenges that are going to influence market growth. The report additionally provides overall details about the business opportunities to key stakeholders to expand their business and capture revenues in the precise verticals. The report will help the existing or upcoming companies in this market to examine the various aspects of this domain before investing or expanding their business in the Perfusion Bioreactor market.

Contact Us:sales@marketresearchupdate.com

More here:
Perfusion Bioreactor Market 2023 | Analysis, Growth Drivers ... - Cottonwood Holladay Journal

The ingestible, electronic fluid-wicking capsule for active stimulation and hormone modulation (FLASH). NYU Tandon School of Engineering

Ozempic, the blockbuster diabetes and weight loss drug, works by mimicking a hormone people produce to feel full. But what if instead of artificially mimicking a hunger hormone, you could stimulate one we already have?

Scientists at NYU are creating anappetite-regulating pill that works by sending electronic pulses out in the stomach, triggering our natural stores of ghrelin a gut hormone that makes people feel hungry. If successful, this technology could be swallowed by patients who are struggling to eat, triggering their natural urge to nibble. People undergoing cancer treatmentor other issues that can make it hard to want to eat, like ARFID (avoidant/restrictive food intake disorder), are some of the groups that could initially be helped by this tool.

The reverse is theoretically also true researchers speculate the same technology could one day be harnessed in a slightly different way to stop people from feeling hungry if they struggle with overeating.

The pill has only been tested in pigs so far, but NYU Assistant Professor Khalil Ramadi, a bioengineering expert who helped invent the new pill, told Insider that the tech after it is safely manufactured for people and OK'd by the US Food and Drug Administration could be tried out in humans within the next five years.

"It's fundamentally a new concept for how we can treat disease," Ramadi said. Without any drugs or surgery, "we can actually increase hunger promoting hormones," just by stimulating the ones the body already has on board.

The pill is essentially a bit of electronic coil that delivers electronic stimulation only when it comes in contact with gastric juices in the stomach. It's wrapped inside a special coating that is designed to pop off once it touches gastric fluids, turning the pill on for about 20 to 30 minutes, and stimulating the hunger-increasing hormone ghrelin.

Giles Yeo, a professor of neuroscience at Cambridge who studies how brains control body weight, told Insider the idea is a "wonderful concept." Yeo was not involved in creating the pill.

"The concept of manipulating gut hormones I think is a good one, in either direction increase or decrease," he said.

Both Yeo and Ramadi say it's easy to imagine such an appetite-stimulating pill working in reverse: Making an appetite-suppressing therapy like Ozempic, but without any drugs involved. Ramadi imagines a future electric pill competing with Ozempic by stimulating the vagus nerve in the area of the lower chest where the esophagus meets the stomach, a technique that's alreadybeen shown to blunt hunger signals in patients who have had that nerve stimulated surgically.

Yeo suggested, alternatively, that a pill could be dispatched further down in the body, beyond the stomach and inside the gut, where more of our appetite-suppressing hormones hang out.

There are still many challenges that scientists need to work out before such a pill will be ready for swallowing by humans.

Any electrical stimulation to the stomach, esophagus, or intestines has to be very precisely targeted. Otherwise, it's possible that the hunger-increasing and hunger-decreasing hormones comingling in our stomachs could just cancel each other out, doing nothing at all to change our appetites. On top of that, the pill's side effects still need to be worked out gut hormones are very sensitive, and if you excite them too much you can end up with vomiting or explosive diarrhea.

Another issue is that the pill isn't really biodegradable, so it's not technically a flushable, marketable design yet. In its current state, people would either have to take the pill in a controlled setting like a hospital, where their stool can be collected, or they'd have to fish their electric pill out of the toilet afterwards, a rather unappealing process.

But if the pill is ultimately successful as an appetite-suppressant, Yeo imagined it could be one more tool in the "arsenal" of newfound appetite drugs, like Ozempic and Mounjaro.

"Maybe I'm someone that needs to lose a few pounds," he said. "So I don't need a big drug in me, I just need to feel a little bit less hungry, for the next month."

Loading...

Visit link:
Pill could be alternative to Ozempic, used to increase or decrease hunger - Insider