Category Archives: BioEngineering

This summer, Jonathan Penman, 24, a college student at the University of Nebraska Omaha, enrolled in a clinical trial of an experimental vaccine for COVID-19.

The virus, he said, was a wake-up call.

I did the vaccine trial because I have a couple of grandmothers who live at our familys home, and my mom works in a preschool, Penman told Healthline. There are people close to me who are susceptible to the virus.

Penman is a participant in the phase 2 trial of mRNA-1273, a vaccine candidate from Moderna, a pharmaceutical company in Cambridge, Massachusetts.

Penman had to drive only a few minutes from his apartment in Omaha to take part in the trial at Meridian Clinical Research.

He received the second of two vaccine injections 2 weeks ago.

I was the first one in the Omaha area to do this trial, he said. So far, so good. Im a little tired from the second injection. Theres a little malaise, but thats about it.

Penman thinks that no matter what happens, he made the right decision.

I think its certainly possible that this could save my life. But we, of course, have no way of knowing, he said.

Penman is grateful that his girlfriend, Morgan, and his friends were supportive of his decision to enter the trial.

I ran this by my girlfriend, who is in nursing school, and she was like, Yeah, if you think you should, do it, go for it, he said.

We have had lot of discussions about this. A few people we know and in my family are anti-vaccine. So, it is a conflict, but not anything major, he added.

Penman said he has friends whove had COVID-19.

I have encouraged people on my Facebook page to do the trial because its the right thing to do. I also encourage them to please wear a mask, he said.

Penman said that thankfully, no one close to him has died from the virus.

I have no idea if I have been exposed or not, he said. But as part of the trial, they have done the swabs. Had I been exposed, that would have showed up there.

The first COVID-19 test he took was before the vaccination, just to make sure he didnt have it.

It came back negative, so I took the first shot, he said. They did my vital signs, it was all good. Then a month later, we did the same thing, and again it was negative.

Penman said the trial wasnt intrusive. But he checked it out before he went through with it.

I Googled it, and the whole concept of the trial works. It makes sense, he said. Its not just a typical vaccination. It attacks the RNA and DNA structure of the virus. That is serious bioengineering. Thats pretty cool.

Moderna is deploying its so-called mRNA platform to develop its vaccine.

While most vaccines use injected viruses to initiate an antibody response, Modernas technology uses viral genetic material RNA to produce the antigens that allow the body to learn to respond to the novel coronavirus.

Moderna is testing to see if its vaccine can help the immune system produce effective antibodies against the virus so that, in case of infection, the virus doesnt cause illness.

As of September 11, more than 23,000 people were enrolled in Modernas phase 3 trial.

All participants will be given an injection half of them with the vaccine, half of them with a placebo. Each group is given a second injection 28 days later.

The total participant enrollment plan for the trial is 30,000.

Why has Moderna been able to make it to a phase 3 trial with relative speed compared with some of the larger U.S. pharmaceutical companies?

Our mRNA platform was already built. It gave us speed, Ray Jordan, Modernas chief corporate affairs officer, told Healthline.

We began making doses for 30,000 participants when we were still in a phase 1 trial, Jordan said. It looked like it was not smart fiscal management. But you take that risk so you can move that much more rapidly.

Jordan explained that the company has been working on vaccines using this technology for a decade. The company has nine vaccine candidates in development against everything from respiratory infections to infections transmitted from mother to baby.

Jordan noted that more than 1,900 participants have been enrolled in Modernas infectious disease vaccine trials in the United States, Europe, and Australia. These are trials other than the one for the novel coronavirus.

People say that we got the virus into the clinic in 63 days. But its really been 10 years and 63 days, Jordan said.

When it comes to the development of a COVID-19 vaccine, no one knows for sure what will happen in the coming months or even years.

But theres increasing though guarded optimism in the scientific community that there will be a vaccine or more than one thats effective.

President Trump has said he wants to develop a vaccine as soon as possible, even if the phase 3 trials arent completed. In early August, Trump said he was optimistic that a vaccine would be ready by Election Day on November 3.

Late last month, Dr. Stephen Hahn, the commissioner of the Food and Drug Administration (FDA), said his agency could consider emergency use authorization or approval for a COVID-19 vaccine before phase 3 trials are complete.

But the chief executive officers at nine of the largest Western pharmaceutical companies with a vaccine being studied wrote a letter pledging that in their efforts to develop a COVID-19 vaccine, they wont take shortcuts and will adhere to the scientific process.

We, the undersigned biopharmaceutical companies, want to make clear our on-going commitment to developing and testing potential vaccines for COVID-19 in accordance with high ethical standards and sound scientific principles, the pledge reads.

The executives who signed the pledge are from Moderna, AstraZeneca, BioNTech, Pfizer, Novavax, Sanofi, GlaxoSmithKline, Johnson & Johnson, and Merck.

Explaining why they wrote the letter, Pfizer CEO Albert Bourla, DVM, PhD, told NBC News, We saw it as critical to come out and reiterate our commitment that we will develop our products, our vaccines, using the highest ethical standards and the most scientific processes.

COVID-19 vaccine clinical trials are also being run by such companies as CanSino Biologics, Inovio, Sinovac, Gamaleya Research Institute of Epidemiology and Microbiology, CureVac, and Clover Biopharmaceuticals.

Russia and China are also developing vaccines.

Penman is optimistic about the possibilities of having a COVID-19 vaccine relatively soon.

Meanwhile, his eyes are firmly focused on the future.

Penman wants to get a federal emergency management position. He plans to join the National Guard and is trying to get a commission through the Reserve Officers Training Corps (ROTC).

Im going to try to get an officer position in the government. I would like to work in Homeland Security. But honestly, whatever is available, he said.

Penman has developed an interest in the concept of government intervention and public health since he decided to enroll in the clinical trial.

Im just curious about it, he said. Will the vaccine be mandatory? And what does that say about civil liberties? To what extent will government make it mandatory?

Penman said he has been reading lately about how the United States is one of the only countries where people are protesting the wearing of masks.

Its interesting. We are pretty defensive in this country about our liberties, he said.

But I encourage people to do the right thing. I encourage people to wear a mask. I have been exposed. Ive had friends around me who have gotten it. But some people just dont take it seriously.

Originally posted here:
COVID-19 Vaccine Trial Participant: 'It's the Right Thing to Do' - Healthline

Chitosan Derivatives Market research report is the new statistical data source added by A2Z Market Research. It uses several approaches for analyzing the data of target market such as primary and secondary research methodologies. It includes investigations based on historical records, current statistics, and futuristic developments.

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Chapter 1 Chitosan Derivatives Market Overview

Chapter 2 Global Economic Impact on Industry

Chapter 3 Global Market Competition by Manufacturers

Chapter 4 Global Production, Revenue (Value) by Region

Chapter 5 Global Supply (Production), Consumption, Export, Import by Regions

Chapter 6 Global Production, Revenue (Value), Price Trend by Type

Chapter 7 Global Market Analysis by Application

Chapter 8 Manufacturing Cost Analysis

Chapter 9 Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10 Marketing Strategy Analysis, Distributors/Traders

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Stainless Steel Fermenter Market Competitive Insights, Business Strategy Opportunities & Demand Analysis Till 2026 | Eppendorf, Sartorius, Thermo...

Edward W. Merrill, professor emeritus of chemical engineering, died peacefully at his home on Aug. 6 at the age of 96, surrounded by his children and grandchildren.

A longtime chemical engineer at MIT, Merrill was a founding contributor to the field of biological engineering. He developed the area of biomaterials and over a 66-year career pioneered several fields of bioengineering.

Ed made an indelible mark on each life he touched, professionally and personally. Not only did his research contributions help better the lives of thousands, but his commitment to education and mentorship helped shape a generation of biomedical engineers, says Paula Hammond, the David H. Koch (1962) Professor in Engineering and head of the MIT Department of Chemical Engineering. I experienced it first-hand as a student and a co-teacher; he raised the bar for all of us.

Born in New Bedford, Massachusetts, on Aug. 31, 1923, Merrill grew up in Jamaica Plain and West Roxbury, Massachusetts, and attended the Roxbury Latin School prior to entering Harvard College in 1941 to study the classics. He received a BA in chemistry from Harvard University in 1944 and pursued doctoral studies at MIT under the direction of Herman P. Meissner. Merrill received his ScD in 1947 working on pioneering theories and experimental studies of polymer adhesion. Upon graduation, he was employed by Dewey and Almy (later part of W.R. Grace) and joined MIT as an assistant professor of chemical engineering in 1950. Merrill was appointed the Carbon P. Dubbs Distinguished Professor of Chemical Engineering in 1973, a position he held until 1998. Merrill was a visiting lecturer in chemistry at Harvard University from 1952 to 1958, a consultant at the Peter Bent Brigham Hospital of Boston from 1960 to 1972, a consultant of the Children's Hospital in Boston from 1969 to 1972, and a consultant of the Beth Israel Hospital in Boston from 1969 to 1985. He has also served as chief scientist and consultant in biochemical engineering to Harvard University Health Services from 1984 to 1998.

In the 1950s and '60s, Merrill was the leading scientist in blood rheology. He investigated the effect of the hematocrit, various plasma proteins, and white blood cells on blood viscosity and flow behavior, and he developed appropriate experimental tools for rheological investigations of blood (including the patented GDM [Gilinson-Dauwalter-Merrill] viscometer) under realistic in-vitro conditions. In the 1960s and 1970s, Merrill was a pioneer in the development of the artificial kidney, analysis of its transport characteristics, and optimization of hemodialyzer membranes. In fact, Merrill's pioneering work on artificial kidneys, with Professor Clark Colton PhD 69 and Robert A. Britton ScD 67, led to the development of the first National Institutes of Health guidelines for artificial kidneys in the 1960s. In the 1960s, '70s, and '80s, he pioneered the field of protein/polymer interaction under stagnant and flow conditions and made exceptional contributions in the development of hydrogels as biomaterials, and in ionic or covalent heparinization techniques on polymer surfaces for antithrombogenic materials.

Merrill and Edward Saltzman of Harvard proposed polyethylene oxide (PEO) as a highly biocompatible material in an influential 1979 paper and did significant studies to analyze its stricture and blood response. Merrill's ideas on PEO as a non-thrombogenic biomaterial led to an explosion in the use of PEG- and PEO-decorated biomedical systems. In 1973, Merrill pioneered silicone-based contact lenses that became the basis of the hard, oxygen-permeable contact lens technology. Merrill's work on highly cross-linked polyethylene in the 1990s with William H. Harris led to the new irradiation-cross-linked, high density polyethylene (HDPE) materials used in artificial joints such as knee and hip replacements.

Merrill's contributions in the area of biomedical applications of aerosol engineering were also significant and led to the use of dipalmitoyl-lecithin aerosols for treatment of infants born with hyaline membrane disease (respiratory distress syndrome). Finally, he made significant and sustained contributions to drag reduction phenomena. Merrill was the inventor of more than 40 U.S. patents and about 230 international patents.

Professor Merrill was probably the premier biomedical engineer of the 20th century, says Nicholas Peppas ScD 74, the Cockrell Family Regents Chaired Professor at the University of Texas at Austin and advisee of Merrill, Not only did he develop the fundamentals of the field, and came up with pioneering inventions of blood flow rheometers, non-thrombogenic biomaterials, advanced contact lenses, treatments of the respiratory distress syndrome, and the most successful materials for joint replacements, but he also became a superb educator and mentor who directed and advised hundreds, if not thousands, of biomedically-oriented students of diverse backgrounds and nationalities.

Merrill personally supervised 57 PhD and 62 MS students, and 12 postdocs in his career. About 35 of these became professors in engineering, sciences, or medicine in academic institutions. About 20 of them became entrepreneurs serving as CEOs or other leaders of the chemical, biomedical or pharmaceutical industries. Merrill and eight of his former students or associates were listed in the 2008 AIChE list of "100 Eminent Chemical Engineers of the Modern Era. Fifty-five of his academic descendants are members of the major academies now: 28 are National Academy of Engineering (NAE) members, 19 are members of the National Academy of Medicine (NAM), three are National Academy of Sciences (NAS) members, and five are members of the American Academy of Arts and Sciences (AAAS). Many U.S. and international companies have been founded on his pioneering research ideas by his students and others.

A superb teacher, Merrill taught courses on polymers, biomaterials, transport phenomena, and medical sciences at MIT. His MIT course entitled Chemical Engineering in Medicine and Biology, offered in 1963, was the first such course in the United States. Merrill was a concerned educator and mentor who welcomed in his laboratories numerous scientists from other countries. He had a close association with Paul Rempp of the Macromolecular Center of Strasbourg, France, and in 1991 wrote an impactful book on polymers with him, Polymer Synthesis. At that time, he was also a vice-president of the Boston-Strasbourg Sister City Association and a director of the Alliance Franaise of Boston-Cambridge from 1990-96. He was also consultant to the conservator of the Department of Prints, Drawings, and Photographs at the Museum of Fine Arts, Boston from 1988 to 1998.

Merrill was elected a member of the AAAS, the NAE, the NAM, and the National Academy of Inventors. He received the Founders Award of the American Institute of Chemical Engineers (AIChE) in 2000, the Founders Award of the Society for Biomaterials (SFB) in 2003, and the Pierre Galletti Award from the American Institute of Medical and Biological Engineers in 2010. AIChE had also bestowed upon him the 1982 Alpha Chi Sigma Award and the 1993 Charles M. A. Stine Award. In 1990, the SFB awarded him the Clemson Award. At its centennial celebration in 2008, AIChE recognized him as one of the 100 Eminent Chemical Engineers of the Modern Era.

Merrill married Genevieve "Ginette" de Bidart on Aug. 19, 1948, in Cambridge, Massachusetts. Ginette passed away seven months earlier on Dec. 20, 2019. They are survived by their daughter Anne and son Frank Merrill, and their grandchildren: James, Sasha, and Julia Merrill. Merrill took great pride in his two children and three grandchildren and enjoyed the time he spent with them immensely. He was not simply a father and grandfather, but a mentor and inspiration to all who encountered him. His presence and his wisdom will sorely be missed by all whose lives he touched, and he will be greatly missed by his family. The family has already held private services.

See more here:
Professor Emeritus Edward Merrill, chemical engineer who helped found the field of bioengineering, dies at 96 - MIT News

Miami, Sept. 18, 2020 In an ongoing effort to expand post-graduate opportunities for its students, Miami Dade College (MDC) has established a 4+1 articulation agreement with Florida Atlantic University (FAU) that will allow MDC graduates with a bachelors degree in engineering, data analytics or information systems technology to complete a masters degree at FAU in one year.

MDC has a history of providing excellence in academics, as demonstrated by this partnership with FAU, said Anselm Knights, MDC chairperson of engineering, technology and architecture. This partnership epitomizes the quality we have put into our programs, and we look ahead to a continued collaboration with FAU and further developing the programs we offer.

The agreement assures that students graduating from MDCs School of Engineering and Technology with a Bachelor of Science in electrical and computer engineering technology, upon meeting specific requirements, are eligible for admission into the Master of Science in Electrical Engineering or the Master of Science in Bioengineering programs at FAUs College of Engineering and Computer Science.

Equally, MDC students graduating with a Bachelor of Science in data analytics or Bachelor of Science in information systems technology can complete FAUs Master of Science in information technology and management in one year after completing the program requirements.

This expanded partnership program will enable MDC students to pursue a masters degree in electrical engineering, bioengineering, or information technology and management, said Dr. Stella Batalama, dean of the FAU College of Engineering and Computer Science. We look forward to welcoming these students to our College, and we are excited for them to join the FAU family.

For more information about the articulation agreement visit: http://mdc.tips/fau-ecet

About Miami Dade College

Miami Dade College is the most diverse institution in the nation. There are 174 nations and 69 languages represented in its student body. The colleges eight campuses and outreach centers offer more than 300 distinct degree pathways including associate and baccalaureate degrees, career certificates and apprenticeships. Baccalaureate degree offerings include biological sciences, engineering, data analytics, information systems technology, education, public safety, supervision and management, nursing, physician assistant studies, film, and others. MDC is the recipient of many top national awards including the Aspen Prize. As Democracys College, MDC changes lives through accessible, high quality-teaching and learning experiences. It is the home of the Miami Culinary Institute, the Miami Animation & Gaming International Complex, the Miami Fashion Institute, the Eig-Watson School of Aviation, The Idea Center, the Cybersecurity Center of the Americas, the Cloud Computing Center, the Center for Learning, Innovation and Simulation, the School for Advanced Studies, and the New World School of the Arts, to name a few of its most innovative programs. MDC has been named among the nations Great Colleges to Work For since the programs inception. The College embraces its responsibility to serve as an economic, cultural, and civic leader for the advancement of our diverse global community. Its alumni and employees contribute more than $3 billion annually to the local economy, and MDC graduates occupy top leadership positions in every major industry. MDC is renowned for its rich cultural programming. It is the home of the Miami Book Fair, Miami Film Festival, the National Historic Landmark Miami Freedom Tower, the Tower Theater, Dyer Building, Koubek Center Mansion and Gardens, the Lynn and Louis Wolfson II Florida Moving Image Archives, the Museum of Art and Design, a sculpture park and a large campus art gallery and theater system. MDC has admitted more than 2,000,000 students and counting, since it opened its doors in 1960. For more information, visit http://www.mdc.edu.

About Florida Atlantic University

Florida Atlantic University, established in 1961, officially opened its doors in 1964 as the fifth public university in Florida. Today, the University, with an annual economic impact of $6.3 billion, serves more than 30,000 undergraduate and graduate students at sites throughout its six-county service region in southeast Florida. FAUs world-class teaching and research faculty serves students through 10 colleges: the Dorothy F. Schmidt College of Arts and Letters, the College of Business, the College for Design and Social Inquiry, the College of Education, the College of Engineering and Computer Science, the Graduate College, the Harriet L. Wilkes Honors College, the Charles E. Schmidt College of Medicine, the Christine E. Lynn College of Nursing and the Charles E. Schmidt College of Science. FAU is ranked as a High Research Activity institution by the Carnegie Foundation for the Advancement of Teaching. The University is placing special focus on the rapid development of critical areas that form the basis of its strategic plan: Healthy aging, biotech, coastal and marine issues, neuroscience, regenerative medicine, informatics, lifespan and the environment. These areas provide opportunities for faculty and students to build upon FAUs existing strengths in research and scholarship. For more information, visit fau.edu.

FAU Media-only contact: Gisele Galoustian, media relations director for research, 561-985-4615, ggaloust@fau.edu.

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MDC and FAU Announce Articulation Agreement for Master's Degree in Technology and Engineering Programs - The Reporter

Nisin Industry 2020 Global Market research report studies the latest Nisin industry aspects market size, share, trends, Opportunities and Strategies To Boost Growth, business overview, revenue, demand, marketplace expanding, technological innovations, recent development, and Nisin industry scenario during the forecast period (2020-2025).

The major players profiled in this report include:DSM, Dupont, Galactic SA, Handary S.A., Siveele B.V., Zhejiang Silver-Elephant Bioengineering, Shandong Freda Biotechnology, Chihon Biotechnology, Mayasan Biotech, Cayman Chemical

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Global Nisin Market is valued approximately USD 423.9 million in 2019 and is anticipated to grow with a healthy growth rate of more than 4.5 % over the forecast period 2020-2027. Nisin is a polycyclic antibacterial peptide that is produced by fermentation of food-grade bacteria and used as a food preservative. Nisin increases the shelf life of the food products, thus widely used in processed food, majorly in dairy products, canned food, and meat products. The global Nisin market is facing challenges in the production facilities fully functional due to shortage of staff and resources amidst the COVID-19 (Coronavirus) outbreak. The effective and non-toxic properties than other natural preservatives, nisin acts as a natural preservative with therapeutic benefits, consumer awareness for clean label products are the few factors responsible for growth of the market over the forecast period. Furthermore, the introduction of new products and other strategic alliance by the market players will create a lucrative demand for the market. For instance: In December 2019, Royal DSM acquired Royal CSK (Friesland), a leading food ingredient company in the European region. This acquisition enables both the company to expand their product portfolio and expertise in food & beverage business. However, crucial and sensitive production and use of preservation techniques to discourage demand for nisin are the major factors restraining the growth of global Nisin market during the forecast period.

The regional analysis of global Nisin market is considered for the key regions such as Asia Pacific, North America, Europe, Latin America and Rest of the World. North America is the leading/significant region across the world in terms of market share owing to the the increase in consumer preference for synthetic food preservatives. Whereas, Asia-Pacific is also anticipated to exhibit highest growth rate / CAGR over the forecast period 2020-2027.

Major market player included in this report are:DSMDupontGalactic SAHandary S.A.Siveele B.V.Zhejiang Silver-Elephant BioengineeringShandong Freda BiotechnologyChihon BiotechnologyMayasan BiotechCayman Chemical

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming eight years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within each of the regions and countries involved in the study. Furthermore, the report also caters the detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, the report shall also incorporate available opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:

By Application:Meat, poultry & seafood productsDairy productsBeveragesBakery & confectionery productsCanned & frozen food productsOthers

By Region:North AmericaU.S.CanadaEuropeUKGermanyFranceSpainItalyROE

Asia PacificChinaIndiaJapanAustralia South KoreaRoAPACLatin AmericaBrazilMexicoRest of the World

Furthermore, years considered for the study are as follows:

Historical year a?? 2017, 2018Base year a?? 2019Forecast period a?? 2020 to 2027

Target Audience of the Global Nisin Market in Market Study:

Key Consulting Companies & AdvisorsLarge, medium-sized, and small enterprisesVenture capitalistsValue-Added Resellers (VARs)Third-party knowledge providersInvestment bankersInvestors

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1 Market Overview1.1 Product Definition and Market Characteristics1.2 Global Nisin Market Size1.3 Market Segmentation1.4 Global Macroeconomic Analysis1.5 SWOT Analysis

3 Associated Industry Assessment3.1 Supply Chain Analysis3.2 Industry Active Participants3.2.1 Suppliers of Raw Materials3.2.2 Key Distributors/Retailers3.3 Alternative Analysis3.4 The Impact of Covid-19 From the Perspective of Industry Chain

4 Market Competitive Landscape4.1 Industry Leading Players4.2 Industry News4.2.1 Key Product Launch News4.2.2 Expansion Plans

5 Analysis of Leading Companies5.1 Company 15.1.1 Company 1 Company Profile5.1.2 Company 1 Business Overview5.1.3 Company 1 Nisin Sales, Revenue, Average Selling Price and Gross Margin (2015-2020)5.1.4 Company 1 Nisin Products Introduction

5.2 Company 25.2.1 Company 2 Company Profile5.2.2 Company 2 Business Overview5.2.3 Company 2 Nisin Sales, Revenue, Average Selling Price and Gross Margin (2015-2020)5.2.4 Company 2 Nisin Products Introduction

5.3 Company 35.3.1 Company 3 Company Profile5.3.2 Company 3 Business Overview5.3.3 Company 3 Nisin Sales, Revenue, Average Selling Price and Gross Margin (2015-2020)5.3.4 Company 3 Nisin Products Introduction

5.4 Company 45.4.1 Company 4 Company Profile5.4.2 Company 4 Business Overview5.4.3 Company 4 Nisin Sales, Revenue, Average Selling Price and Gross Margin (2015-2020)5.4.4 Company 4 Nisin Products Introduction

6 Market Analysis and Forecast, By Product Types6.1 Global Nisin Sales, Revenue and Market Share by Types (2015-2020)6.2 Global Nisin Market Forecast by Types (2020-2026)6.3 Global Nisin Sales, Price and Growth Rate by Types (2015-2020)6.4 Global Nisin Market Revenue and Sales Forecast, by Types (2020-2026)

7 Market Analysis and Forecast, By Applications7.1 Global Nisin Sales, Revenue and Market Share by Applications (2015-2020)7.2 Global Nisin Market Forecast by Applications (2020-2026)7.3 Global Revenue, Sales and Growth Rate by Applications (2015-2020)7.4 Global Nisin Market Revenue and Sales Forecast, by Applications (2020-2026)

8 Market Analysis and Forecast, By Regions8.1 Global Nisin Sales by Regions (2015-2020)8.2 Global Nisin Market Revenue by Regions (2015-2020)8.3 Global Nisin Market Forecast by Regions (2020-2026)Continued.

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Global Nisin Market set to grow with massive rate by 2020 to 2025 - The Daily Chronicle