Category Archives: Biochemistry

A University of Canterbury student is researching key cell biology processes that may be useful in curing or slowing down the development of many diseases such as strokes and heart attacks.

Nelsons Ben Walters is at the end of his fourth year of UC study working toward a Master of Science in Biochemistry. His area of research is on cardiovascular disease which is a leading cause of mortality in most developed countries, largely due to the ageing population and sedentary lifestyles.

In New Zealand heart attacks and strokes result are responsible for 40 percent of annual deaths, affecting around 10,000 people. Cardiovascular disease involves the build-up of fatty materials such as cholesterol in the cells within the arterial walls in a process known as atherosclerosis.

Fat deposition within the cells begins in teenage years and after enough time, blood circulation can be impaired through artery stiffening and plaque formation. These plaques can eventually rupture and form blood clots that deprive tissues of oxygen and other nutrients.

Depending on the location of clot formation, the resulting tissue damage can be in the form of a heart attack or stroke.

My project is looking at how cells involved in cardiovascular disease regulate production of an antioxidant called 7,8-dihydroneopterin. Antioxidants are protective molecules that protect cells against oxidative stress, a process involved in cardiovascular as well as many other diseases, Walters said today.

An increased understanding of how cells produce such molecules many one day lead to therapeutic drugs to modulate antioxidant production. Such interventional strategies may be useful in curing or slowing down the development of many diseases.

Biochemistry and medical research are extraordinarily fields to be involved in. Everything feels incredibly applicable, as the very processes we learn about are occurring inside ourselves and all other life on the planet.

It is also very rewarding to know that the relatively small contribution that I am making to the vast scientific literature, may one day lead to the development of medicines which could save and improve the quality of millions of lives around the world.

The University of Canterbury has been a great place to study, where world leading facilities/research laboratories and excellent teaching staff means anyone with the inclination can be inspired and excel in their field of interest.

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Researching potential curing or slowing down of cardiovascular disease

Emergent Computation
ll4.me Emergent Computation Part 1: Automata Theory and the Biochemistry of Genetics; A Review of Chemistry; A Review of Automata Theory; The Beginning Numbers; Regular Languages: DNA and RNA; Context Free Languages: DNA and RNA; Context Sensitive Languages: DNA, RNA, Proteins; Turing Machines and SubTuring Machines; Splicing Systems, H Systems; tRNA Structure; Semigroups and BioInformatics.- - Part II: Automata Theory and Disciplines Other Than Bioinformatics; Automata Theory: non-Bioinformatics Emergent Computation. Appendix. References. Index EAN/ISBN : 9780387272702 Publisher(s): Springer, Berlin, Springer, New York Discussed keywords: Bioinformatik Format: ePub/PDF Author(s): Simon, Matthew Part 1: Automata Theory and the Biochemistry of Genetics; A Review of Chemistry; A Review of Automata Theory; The Beginning Numbers; Regular Languages: DNA and RNA; Context Free Languages: DNA and RNAFrom:kennethhagerman985Views:0 0ratingsTime:00:13More inPeople Blogs

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Getting Ready for a BioPharma Partnering Deal with Linda Pullan from Pullan Consulting
View this ShareVault webinar with Linda Pullan from Pullan Consulting on Getting Ready for a Bio-Pharma Oarnt Agenda: » Should you partner now? » Valuation basics » Process to a deal » Negotiations prep » Negotiations » Term sheets » On to the full agreement Speaker Biography: Linda M. Pullan, Ph.D. offers biotech and pharmaceutical companies consulting in all aspects of partnering through Pullan Consulting (www.pullanconsulting.com). Linda has a Ph.D. in Biochemistry and a BS in Chemistry. Linda has more than 20 years of drug industry experience, beginning in drug discovery at Monsanto/Searle/now Pfizer and ICI/Zeneca/now AstraZeneca. After doing licensing at what is now AstraZeneca, Dr. Pullan continued as head of oncology and hematology licensing for Amgen. She then joined Kosan Biosciences as VP of Business Development and experienced all the tasks of out-licensing and business development in a small company. For several years, she has been providing companies help in identification, evaluation, valuation, negotiation and strategy for partnering in or out. She has an extensive deal sheet ranging from company acquisitions to Phase III compounds and from preclinical candidates to technologies, with both in- and out-licensing. She writes a free monthly newsletter Pullan #39;s Pieces, with tidbits of science and business for about 3600 readers. Interested readers may sign up by sending an email to lpullan@msn.com. Learning Objectives: » Basics of Valuation » Dealmaking ...From:ShareVaultViews:0 0ratingsTime:55:29More inEducation

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E-study Guide For: Introduction To General, Organic And Biochemistry By Frederick A. Bettelheim, Isb
ll4.me E-study Guide For: Introduction To General, Organic And Biochemistry By Frederick A. Bettelheim, Isbn 9780495391128 - Cram101 Textbook Reviews Never Highlight a Book Again! Just the FACTS101 study guides give the student the textbook outlines, highlights, practice quizzes and optional access to the full practice tests for their textbook.Author: Reviews, Cram101 Textbook Publisher: Cram101 Illustration: N Language: ENG Title: e-Study Guide for: Introduction to General, Organic and Biochemistry by Frederick A. Bettelheim, ISBN 9780495391128 Pages: 00300 (Encrypted EPUB) On Sale: 2012-06-19 SKU-13/ISBN: 9781467256247 Category: Education : General Never Highlight a Book Again! Just the FACTS101 study guides give the student the textbook outlines, highlights, practice quizzes and optional access to the full practice tests for their textbook. Au education, cram101 textbook reviews, generalFrom:rebeccasmith98774Views:0 0ratingsTime:00:16More inPeople Blogs

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E-study Guide For: Introduction To General, Organic And Biochemistry By Frederick A. Bettelheim, Isb - Video

Cosmos: One Voice in the Cosmic Fugue- Episode 2
Air Date: October 5, 1980. Sagan discusses the story of the Heike crab and artificial selection of crabs resembling samurai warriors, as an opening into a larger discussion of evolution through natural selection (and the pitfalls of intelligent design). Among the topics are the development of life on the Cosmic Calendar and the Cambrian explosion; the function of DNA in growth; genetic replication, repairs, and mutation; the common biochemistry of terrestrial organisms; the creation of the molecules of life in the Miller-Urey experiment; and speculation on alien life (such as life in Jupiter #39;s clouds). In the Cosmos Update ten years later, Sagan remarks on RNA also controlling chemical reactions and reproducing itself and the different roles of comets (potentially carrying organic molecules or causing the Cretaceous--Paleogene extinction event). Playlist for whole episode: Cosmos: A Personal Voyage- http://www.youtube.com Episode 1- The Shores of the Cosmic Ocean http://www.youtube.com Episode 2- One Voice in the Cosmic Fugue http://www.youtube.com Episode 3- The Harmony of the Worlds http://www.youtube.com Episode 4- Heaven and Hell http://www.youtube.com Episode 5- Blues for a Red Planet http://www.youtube.com Episode 6- Travellers #39; Tales http://www.youtube.com Episode 7- The Backbone of Night http://www.youtube.com Episode 8- Journeys in Space and Time http://www.youtube.com Episode 9- The Lives of the Stars http://www.youtube.com Episode 10- The Edge of Forever http://www.youtube.com Episode 11- The Persistence of Memory http://www.youtube.com ...From:sasijayaramViews:0 0ratingsTime:01:00:12More inEducation

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Enzyme Kinetics And Mechanism, Part F: Detection And Characterization Of Enzyme Reaction Intermediat
ll4.me Enzyme Kinetics And Mechanism, Part F: Detection And Characterization Of Enzyme Reaction Intermediates: Methods In Enzymology - Daniel L. Purich The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant todaytruly an essential publication for researchers in all fields of life sciences.Key Features* Spectroscopic Detection of Reaction Intermediates* Isotopic and Kenetic Detection of Reaction Intermediates* Chemical Trapping and Inhibitor Methods for Detecting Reaction IntermediatesAuthor: Purich, Daniel L. Publisher: Academic Press Illustration: N Language: ENG Title: Enzyme Kinetics and Mechanism, Part F: Detection and Characterization of Enzyme Reaction Intermediates: Methods in Enzymology Pages: 00000 (Encrypted PDF) On Sale: 2002-10-21 SKU-13/ISBN: 9780121822576 Category: Science : Life Sciences - Biochemistry Category: Science : Life Sciences - Molecular Biology Category: Science : Life Sciences - Biophysics The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each vol daniel l. purich ...From:cherylrader9854Views:0 0ratingsTime:00:16More inPeople Blogs

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Enzyme Kinetics And Mechanism, Part F: Detection And Characterization Of Enzyme Reaction Intermediat - Video