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- How researchers are mapping the future of quantum computing, using the tech of today – GeekWire
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Bioelectric medicine is coming into its own as a combination or stand-alone therapy for a growing cohort of conditions. Big pharma has funded programs, international coalitions have formed and the National Institutes of Health (NIH) and the Defense Acquisition Research Agency (DARPA) each are making sizeable research investments. The field, panelists at a recent Demy-Colton Virtual Salon agreed, holds huge promise.
Targeted delivery of energy biomedicine can be used to treat chronic diseases of the nervous system, inflammatory conditions, autonomic disorders and metabolic diseases. It may even be possible to treat heart conditions, oncology, pain, and gastric, urologic, and ophthalmic conditions such as chronic dry eye.
Key benefits of this approach include the lack of side effects and possibly expedited regulatory pathways. As panel moderator Beth Rogozinski, CEO, Oncoustics, noted, Were seeing payers with expedited pathways and payers paying for telemed and telepsych at the same rates as in-office visits.
For biomedicine, this is the age of innovation.
At Massachusetts General Hospital, Paolo Cassano, M.D., Ph.D., co-founder Niraxx, and his team use photons of light to modulate brain function.
This can be applied to any organ of the body. We absorb light, make energy from it, reenergize cells, and thus reestablish cellular function, Cassano said. The most obvious target for light is skin, but other applications include muscles, fatigue, and general health, so sports medicine is another big application.
Some of the treatments have effects beyond their neuromodulatory effect, for systemic and local effects, Cassano said.
He specifically noted neuro-oxidative, anti-apoptotic and anti-inflammatory effects. This suggests that bioelectric therapies may control the excess of reactivity of the body and contain the most lethal consequences of an infection and its processes.
Cala Health, in another example, is developing a wearable, watch-like device to address essential tremor in Parkinsons and other neurodegenerative disease.
This is found in the hand, voice or legs of patients and affects their ability for self-care, Renee Ryan, CEO, Cala Health, explained.
The therapeutic options today are surgery or off-label drugs.
We believe a lot of the disease is influenced by the median nerve, so we have a watch-like device that provides stimulation to the radial and median nerves at the wrist. A 40-minute treatment resulted in an average of more than 94 minutes of tremor relief, she added. We usually see the onset of relief after about 10 minutes, and one patient achieved seven hours of relief after an early morning session.
By relieving tremors, she said she expects to also reduce patients depression and anxiety.
Improving cognition is another area of great need. This includes improving patients memory and retention as well as executive function.
With an aging population, we need to keep workforce performance up. Theres also the issue of preventing dementia and mild cognitive impairment, Cassano said.
For COVID-19, biomedicine offers the ability to modulate inflammation, and thus may help control or prevent the cytokine storm and caustic inflammation. Developmental disorders, such as Downs syndrome can be addressed, too.
If we can intervene early, some of these patients may develop their cognitive function to enjoy a fuller, productive, more joyful life.
This is a very exciting time for this industry, Casanno said. Patients are desperate for new solutions, for diseases that have no treatments or no disease-modifying treatments.
Bioelectric medicine differs from biofeedback, panelists pointed out. Neurofeedback is about sensing whats happening in the brain so people can modify their behavior. Bioelectric therapy, in contrast, temporarily modifies the brain function.
That safety profile lends itself to a potentially faster commercialization pathway.
If there is good scientific data and regulatory support, and the therapy isnt invasive, theres an advantage, said Juan-Pablo Mas, partner, Action Potential Venture Capital.
Bioelectronic therapies will have various places in the treatment paradigm, such as being used in combination therapies, replacing drugs, filling therapeutic gaps, proving unique mechanisms of action and catching patients earlier in the disease when surgery isnt an option, Mas said. All will have effects in terms of how disease is treated.
They have a place in wellness also, where they are not regulated.
Thats a big opportunity, Cassano said. But, Once you know a person actually is suffering from a disorder, the disease itself requires monitoring, he cautioned.
Medicine is shifting towards prevention. That should be our goal, Cassano said. So capitalizing on the wellness side is critical, preventing wear and tear of brain that lead to onset of diseases.
As in so many things today, The new normal wont be the old normal, Rogozinski concluded.
LovelySkin, the only dermatologist-owned and operated retailer for all things skin health, has a mandate to provide advanced skin-care solutions. For those of us skin-care lovers who relish professional-grade formulas with serious results, its the ideal market through which to curate your skin-care routine.
LovelySkin is founded by Omaha, NE dermatologist and cosmetic surgeon, Joel Schlessinger, MD who puts his professional medical opinion into each and every product on offer. (You also might find him answering a customer service email or replying to consumers who need help creating an at-home regimen.)
We asked Dr. Schlessinger to talk about some of the brands available on LovelySkin with which he has a level of direct involvement before they come to beauty-lovers like you! He narrowed it down to a handful of must-try favorites. Ahead, youll find his recommendations for fuller-looking lashes, plumper skin, lusher lips, and more, from four favorite brands.
Despite the long name, this science-backed line has a simple premise: creating the fullest-looking lashes and brows in the game. These professional formulas, with a combination of peptides, antioxidants and vitamins, help nourish lashes and brows and create the appearance of length, thickness and volumeare only available through licensed professionals.
These products have been studied at our own clinic as well as independent efficacy and clinical testing says Dr. Schlessinger. My patients love the benefits for lashes and brows alike.
Best For: Lash Enhancement
neuLASH PROFESSIONAL Lash Enhancing Serum by Skin Research Laboratories ($90)Whether youre seeking fuller-looking lashes for an upcoming event or seeking to compliment lash extensions, this antioxidant-rich serum will create lusher- and longer-looking lashes. neuLASH PROFESSIONAL will also upgrade dull, brittle lashes to well hydrated and lustrous ones, perfect for batting in-person or on Zoom. Most users see improvements to their lashes in as little as 3-4 weeks.
Best For: Fuller-Looking Brows
neuBROW PROFESSIONAL Brow Enhancing Serum by Skin Research Laboratories ($90)neuBROW PROFESSIONAL has created the most advanced brow serum using botanicals, vitamins, and five polypeptides. Whether the appearance of your brows has been hindered by a small scar or age, this lightweight serum can help you achieve younger-, healthier-, and stronger-looking brows, says Dr. Schlessinger. Youll notice thicker- and bolder-looking brows in as little as 4-6 weeks.
Best For: Doing It All
neuLASH/neuBROW PROFESSIONAL by Skin Research Laboratories Introductory Kit ($90)Why choose between lashes and brows? Novicesand the curiousshould start out with the Introductory Kit, which comes with half sizes of both the brow and lash serums that should last you for 812 weeks. This kit is the perfect way to get a taste for how healthier-looking, fuller-appearing lashes and brows can contribute to an overall more vibrant and fresh appearance, says Dr. Schlessinger.
This dermatologist-developed skin-care line is focused on anti-aging, exfoliation and barrier repair with serious results. The AFA line combines the unusually exceptional results of a low pH with the accelerated benefits of a professional antioxidant-rich, anti-aging line all with virtually no irritation, says Dr. Schlessinger. Go ahead and get your hopes up, thanks to the products below.
Best For: All-Around Skin Improvement
AFA Exfoliating Gels in Mild ($88), Plus ($94), or Max ($99)Dr. Schlessinger describes these do-it-all skin renewal gels as powerhouse products. Apply after cleansing for a dose of the benefits of highly-effective exfoliation with little to no irritation. In addition to reducing inflammation, correcting hyperpigmentation and fighting free radicals, these gels also help restore the skins moisture barrier, which helps to plump wrinkles and keep skin hydrated and healthy. The Gels are available in three strengthsstart at mild and work your way up, or stick to the style that works best for your skin type.
Best For: Extra-Credit Cleansing
AFA Cleanser with Vitamin C and Dead Sea Minerals ($50)
Who says cleanser is just for makeup and dirt removal? This powered-up foaming, milky cleanser is formulated with vitamin C and Dead Sea minerals to gently exfoliate while it clears away dirt and impurities. Its fragrance-free, making it ideal for sensitive skin types or anyone who wants to start and end their day on a gentle note.
Best For: Professional-Quality Masking
AFA Micro Exfoliating Masque ($66)This clay mask acts like a magnet to draw dead cells, excess oils and impurities out of the skin. Regular use improves sun damage, evens skin tone and texture, minimize the appearance of pores, and helps firm skin, says Dr. Schlessinger. Feel free to dip into this jar of rare clay once or twice per week for an at-home facial that offers you clear-skin goodness.
LovelySkin isnt just a retailer, its also a medically based, dermatologist-developed skin-care line. The line is centered around high-quality, professional-grade ingredients that treat skin conditions from acne to wrinkles.
When I started to consider which products I wanted to offer as my signature line, the first and foremost area of importance was results, says Dr. Schlessinger. Results are the one thing that often are not obvious with skin care products. Because of our unique, medical-grade actives, we offer a unique and effective line that packs a punch while also being gentle in nature as to repair, not damage, the skin barrier.
LovelySkin offers a full suite of products for every step in your skincare routine, but Dr. Schlessinger narrowed it down to four must-try items.
Best For: Acne-Prone Skin
LovelySkin LUXE Clarifying Gel Cleanser ($10 and $40)Formulated with medical-grade salicylic acid, 2-percent glycolic acid and a proprietary blend of seven antioxidants, this cleanser is designed to zap acne before it starts and clear existing breakouts. It is available in two sizes for a deep clean at home or on-the-go.
Best For: Workhorse Exfoliation
LovelySkin LUXE Microdermabrasion Polish with Triple Sphere Technology ($76)This polish offers both environmentally-friendly physical exfoliation and non-irritating chemical exfoliation to quickly reveal brighter, healthier skin, says Dr. Schlessinger. Simply massage into skin for 30 to 60 seconds two or three times per week and youll begin to notice an improvement in the appearance of pores and more luminous, radiant skin.
Best For: A Hero Serum
LovelySkin Vita-CE With Ferulic Acid ($80)Vita-CE With Ferulic Acid is clinically proven to reverse signs of aging, increase collagen production and provide incredible antioxidant protection, says Dr. Schlessinger. This serum attacks signs of aging from all angles, working to promote skin elasticity, correct hyperpigmentation and sunspots, and reduce the appearance of fine lines and wrinkles. It also neutralizes free radicals, which will help protect against environmental and UV-induced skin damageespecially relevant now if you spend plenty of time absorbing blue light from your screens.
Best For: All Things Under-eyes
LovelySkin LUXE Brightening Eye Cream ($90)A brightening eye cream should be a part of every skin-care toolkit. LovelySkins new formula uses the latest ingredients, including SNAP-8 peptides, hyaluronic acid and Persian silk tree extract to strengthen the collagen in your undereye area, thus tightening that sensitive skin. Under-eye puffiness is reduced by horse chestnut extract and if darkness is your main concern, this cream is ready to come to the rescue with optical technology that works to diffuse light and instantly brighten.
Good skin is a family affair thanks to Dr. Schlessingers son Dr. Daniel Schlessinger, with whom he co-created a line of 1-percent hydrocortisone healing balms for lips, face and body. This line offers unique results for a variety of skin conditions including eczema, dry skin, psoriasis, seborrheic dermatitis, and poison ivy, says Dr. Joel Schlessinger. These products are useful in so many situations and the perfect addition to a medicine cabinet or overnight bag.
Best For: Seriously Chapped Lips
FixMySkin 1% Hydrocortisone Healing Lip Balm in Unflavored or Vanilla ($11 each)With winter upon us, now is the perfect time to stock up on a lip balm that will actually get the job done. This Healing Lip Balm is medicated with 1-percent hydrocortisone, a topical steroid that acts as an over-the-counter treatment for smaller areas such as lips, fingers, and facial areas like the eyes experiencing dryness, over-exposure or other irritation.
Best For: Eczema, Cracked Fingers and Dry Skin
FixMySkin 1% Hydrocortisone Healing Body Balm Fragrance-Free ($16)This conveniently sized (.5 oz) balm belongs in your bag, ready to be pulled out in case of skin concerns like eczema, psoriasis, dryness, itchiness, flakiness, or whatever irritation on a larger area needs some extra TLC. Just like its sister lip balm, its formulated with 1-percent hydrocortisone to help soothe everyday accidents and irritations without a greasy mess. Its also fragrance-free, so it wont further irritate skin.
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4 Derm-Approved, Under-the-Radar Skin-Care Brands to Shop on LovelySkin - NewBeauty Magazine
In 2018, therapeutic hemp products with less than .3 percent THC became legal in the United States. Thats led to a boom in products like CBD oil, which boast calming psychological effects, among other benefits. These benefits can be enjoyed in plenty ways, but one of the most unique is through CBD Pre Rolls from TIMBR Organics.
Whatre Hemp Pre Rolls? Well, theyre similar to joints, but theyre packed with hemp flower instead of cannabis. That means instead of getting you high, each TIMBR Organics Hemp Pre Roll will bestow the well known therapeutic benefits of CBD.
TIMBR Organics Hemp Pre Rolls contain hemp in a virtually unprocessed, raw state. This gives them a multitude of advantages over other hemp products, like a rich blend of cannabinoids, terpenes, and flavanoids (otherwise known as the therapeutic nutrients found in cannabis).
These Hemp Pre Rolls from TIMBR Organics are easy to use: just light and smoke. Theyre ready to use without any preparation of any kind. Prices start at $6.99 for a single roll, making it more affordable than some other CBD or hemp products. And their versatility and portability makes them suitable for any lifestyle.
TIMBR Organics offers a variety of flavors for their Hemp Pre Rolls, with names that will provide a comfortable haze of nostalgia. Heres a breakdown:
Earthy foundation and floral flavor notes come together to provide instant relaxation, ideal for an evening in.
A native strain of Oregon that mixes notes of fruit with earthy highlights, and is described as a dense bud and a kaleidoscope of colorful hues. The perfect way to enjoy Sour Space Candy? A movie night in, or in your favorite chair with a good book.
Another Oregon strain, this one with earthy bases and strong citrus overtones so strong that Suver Haze is said to be reminiscent of inhaling an orange grove on a breezy summer day.
Distinguished by its high concentration of cannabinoids, Lifters spiced earth flavor notes and quick action are built to uplift, and its purportedly perfect all-day enjoyment whether youre relaxing at home or doing errands all over town.
Speaking of uplift, thats also the word of the day with Hawaiian Haze. Double-H is optimized for any day that requires a little extra motivation, sativa-dominant and boasting notes of flower, peach, and pineapple.
So if youre ready to light up and enjoy the benefits of all-natural hemp flower, TIMBR Organics CBD Pre Rolls are available to order now, either in single rolls or packs of 12. Check out the selection at the TIMBR Organics online shop.This supplement has not been evaluated by the FDA, and is not intended to cure or treat any ailments. Do not take CBD products if you are allergic to any of the ingredients in the product you are consuming. Tell your doctor about all medicines you may be on before consuming CBD to avoid negative reactions. Tell your doctor about all medical conditions. Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins and herbal products. Other side effects of CBD include: dry mouth, cloudy thoughts, and wakefulness. You are encouraged to report negative side effects of any drugs to the FDA. Visit http://www.fda.gov/medwatch, or call 1-800-FDA-1088.
Specific dietary changes, like including natural supplements, can help in enhancing sexual energy in women. Aphrodisiacs are the foods, drinks, or drugs that help increase female libido. Cannabis is another such natural aphrodisiac that can help increase womens libido. Cannabis can also help in reducing the pain during penetration experienced by some women.
According to a study, women who ate cannabis experienced two times higher sex drives, with satisfactory orgasms than those with irregular cannabis usage. Cannabis interacts with endocannabinoids in the body, which help regulate sexual function. Women can use cannabis as an aphrodisiac in many ways. Earlier, people used to take it in the form of a beverage, but today, there are many different consumption methods. Women can also use cannabis as lubricants, helping in reducing pain during sex.
Mental health disorders affect both men and women, but theyre more severe in women. Various factors like career, family responsibility, and abuse are significant causes of mental issues in women. The most common mental illness in women is depression, bipolar disorder, and schizophrenia, often challenging to diagnose.
According to an article, cannabis has antidepressant traits that help decrease anxiety and depression in women. The depletion of serotonin in the brain leads to depression. However, taking cannabis in low doses helps release serotonin, which causes anti-depressant effects. This can help in alleviating stress and anxiety, as well as assisting in doing day-to-day activities.
These are some of the benefits of cannabis for women. Research states that one should always use cannabis from low doses to reap the right health benefits. Buy cannabis products from reputed shops that will provide authentic cannabis products. Make sure to check the THC and CBD content in the product to understand the dosage. You may need to think twice if you have any medical condition or are taking any medication. If you fall into either of these groups, make sure to consult a health professional before starting cannabis.
Denson, T. F., & Earleywine, M. (2006). Decreased depression in marijuana users.Addictive behaviors,31(4), 738742. https://doi.org/10.1016/j.addbeh.2005.05.052
Lynn, B. K., Lpez, J. D., Miller, C., Thompson, J., & Campian, E. C. (2019). The Relationship between Marijuana Use Prior to Sex and Sexual Function in Women.Sexual medicine,7(2), 192197. https://doi.org/10.1016/j.esxm.2019.01.003
Olh, A., Tth, B. I., Borbr, I., Sugawara, K., et al. (2014). Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes. The Journal of clinical investigation,124(9), 37133724. https://doi.org/10.1172/JCI64628
After a 20-year career in the corporate world, Selam Kelati was ready for a change. Born and raised in Ethiopia, she grew up in a culture where plants and herbs were part of everyday life and utilized in an array of food, medicines, and cosmetics. So, when she decided to build a business of her own, she constructed the frame around her knowledge of natural remedies and homeopathic plants.
Launching a startup in the competitive U.S. cosmetics-and-skincare sector was no small endeavor. The industry is dominated by powerful multinational brands. But with estimated revenues of $645 million in 2019, the CBD segment of the market still offers plenty of room for startups. Kelati, along with business partner Jennifer Culpepper, seized the opportunity and created I+I Botanicals. (The name is pronounced I and I.)
The company takes an eco-conscious, holistic approach that upholds the traditions and ethics Kelati learned at an early age. Our core message is good for the earth, good for the soul and, of course, good for the body, she said. I and I comes from the Rastafarians, who use the words to mean you and I are the same. The message is that the love you give to yourself, try to give it to another.
Kelati and her eight siblings were raised by Eritrean parents and an extended family that passed down recipes for plant-based foods and medicine. Her grandmother was known in her village as an herbal medicine expert who had a deep knowledge of plants in the region and used them to create concoctions for health, beauty, and wellness.
People would come from near and far to get some kind of something that she would mix for medical purposes, so this was in our house and our family, Kelati explained. Anything to do with herbs or medicine or cooking was just a natural thing in our household. You sit with your grandmother and your aunties and your mom and you learn, but you dont even understand you are learning at that age, because its part of your life, right? So thats where my passion for natural ingredients comes from, and its something Ive carried with me throughout my life.
The prickly pear cactus grows abundantly in Eritrea and is utilized in a number of different ways, from making jams to feeding livestock. Pressing the seeds creates an oil that is beneficial for skin and hair, Kelati said, and it also has anti-aging and anti-inflammatory properties. Another ingredient widely used in her native region is moringa oil. The substance is created by processing the seeds and leaves of the moringa tree, which has been dubbed the miracle tree due to its bountiful medicinal and nutritional attributes.
Moringa oil mimics the natural oil we create in our body, so it does help with your hair shine and keeping it healthy and not breaking, Kelati said. And for the skin as well. Its nutrient-dense, which helps reduce the appearance of wrinkles.
There are a lot of people who dont understand that its not just about working hard. Its also about having a starting point.
Kelati has been experimenting with her own natural plant remedies for most of her life and enjoys sharing her creations with friends and family to gather feedback about what works and what does not. Soon after she heard about CBDs anti-inflammatory, antioxidant, and skin-soothing properties, she immersed herself in research. She went to trade shows and networked with operators in the industry. During her investigation, one product, in particular, stood out to her. It was an under-eye cream that [my business partner] Jennifer shared with me, and I remember seeing the puffiness under my eye being reduced within three or four days of using it, she said. That made me a believer.
I told Jennifer I wanted to have my own beauty line based on natural ingredients, because this is what I know and have been taught since childhood, she continued. Theres some kind of magic we can create using CBD. So, Jennifer and I brainstormed and I+I was born in the process.
As working mothers, Kelati and Culpepper understand the unique pressures women face on a daily basis, juggling roles from caregiver to breadwinner and trying to squeeze in time for themselves when and where they can. As such, one of their goals is to give women an easy way to incorporate CBD products into their daily routines and enjoy a relaxing moment or two amid the hustle and bustle.
The global CBD skincare market is expected to reach $1.7 billion by 2025, according to a report by Grand View Research Inc. North America, which accounted for more than 40 percent of the market in 2018, will lead the way, Grand View projected. For brands like I+I, which has a relatively small footprint at this point, establishing a presence in the lucrative space early is crucial. The effort starts with creating unique, compelling products that will stand out from the crowd.
The process Kelati uses to formulate new products is a combination of her homespun plant knowledge and ad hoc testing, with some modern science and technology to clinch the deal. [Jennifer and I] experiment with [a new formulation] ourselves to see how it feels, to get the texture and viscosity we want and the result we want to get, she said. Then we have chemists that we work with, and they produce the product at their facilities.
I+Is original CBD products include moisturizing Dry Oil Body Mist (jojoba oil, moringa oil, and a blend of citrus essential oils), hydrating Face Serum (prickly pear seed oil and hyaluronic acid), and relaxing Bath Tea Blend (essential oils). One of the most popular products, Kelati said, is Coffee Body Scrub, a foaming exfoliator that contains a combination of seven plant extracts, CBD, and fair-trade Ethiopian coffee. This is something we actually use back home after we finish drinking coffee, Kelati said. Using the leftovers, you can scrub it around your feet to make them smooth.
Other ingredients in traditional Ethiopian and Eritrean health and beauty regimens happen to be on-trend in Western markets right now. Called adaptogens, the materials comprise nontoxic plants and plant derivatives that are believed to help the body resist stress. Scientific research and validation for adaptogens is scarce, but adaptogenic concoctions have been used for centuries in Chinese, African, and other cultures. I realized when I looked at the list of ingredients that I knew growing up, they are actually considered adaptogens, although we didnt call them that, Kelati said. So we decided it makes sense to follow up and create products using those ingredients.
The importance of sourcing products from sustainable, eco-conscious farmers and manufacturers cannot be overstated, she said. All the CBD and most other essential ingredients in I+I products are sourced in the U.S., but Kelati also maintains several key partnerships back home. The main ingredients that represent the product are coming from somewhere we actually source ourselves, she revealed.
I+I primarily operates in the beauty segment, but Kelati wants to grow the business into other verticals and develop products that appeal to a wider audience. One thing we are working on is beard oil so we can give something to the guys, she said.
As legalization has swept across the U.S., social equity has become one of the hottest of the hot-button issues in the cannabis and hemp industries. People of color and their advocates are fighting for a bigger stake in a space that is overwhelmingly controlled by White investors and operators. Despite legislation and other efforts designed to promote ownership and participation by Black, Indigenous, and people of color (BIPOC) stakeholders, very little progress has been made thus far.
As a Black female entrepreneur, Kelati understands the challenges. She is all too familiar with the discrimination and other issues people of color face as they try to build brands from the ground up with scarce access to investment or business loans. But none of this has tempered her enthusiasm, and Kelati is eager to build I+Is momentum across the country in 2021, one mist and scrub at a time.
Being a Black woman, I did recognize at an early stage that were going to have a lot of challenges, Kelati said. People are going to have doubts about everything we say. But I do see theres a lack of mentorship and representation, and when we go to trade shows, we dont see a lot of buyers who are minorities. So, its justI have to prepare myself more than my colleagues or my competition [must], because I just want to make sure I am representing myself fully so I can capture the audience.
On a more optimistic note, she said Black women are one of the fastest growing groups in business, and in the beauty industry she believes the situation is becoming more favorable for BIPOC and women. She cited the 15-percent pledge as one example of the changing tides. In June, Sephoraa French multinational chain of personal care and beauty storesannounced its U.S. unit would pledge to grow the share of Black businesses it helps empower to at least 15 percent. The company created an advisory group that includes brands owned by people of color to help make changes. Sephora currently works with about 300 brands in the U.S., where it has more than 400 retail storefronts plus kiosks in J.C. Penney stores.
One of the most critical factors for young businesses is raising capital, and Kelati said that has been a difficult hurdle to surmount. When it comes to attracting investors, or even getting grants or any kind of loan, its not that easy for women of color, she said. Weve been trying to get investors to be attracted to our message and product, but it has been very, very challenging. Definitely, if there is more mentorship and representation, those can make a big difference.
Kelati also noted most Black business owners are new to the business world and dont have the same level of experience, capital, or the connections enjoyed by many White business owners. Everybody does not start from the same beginning, and Black business owners dont have that foundation. We start everything from scratch, she said. So, to expect to go the same speed as the competition who actually have a good jumpstart, its really not fair. When you go networking, you dont see someone who looks like you or someone who understands your struggle. There are a lot of people who dont understand that its not just about working hard. Its also about having a starting point. The experience is not the same.
Kelati has seen some signs over the past year that give her hope for a brighter future for BIPOC-owned businesses. In the meantime, I+I is doing its part to highlight a proud legacy with roots in East Africa being carried forward by modern-day female entrepreneurs.
To be honest, it makes me comfortable now to say that, yes we have a Black woman business owner, and we always promote ourselves as a woman-owned business and my face is out there, she said, explaining that even in the cosmetics industry, women-owned businesses face a steep climb. It just makes us more comfortable now because we feel like the [equity] movement [in cannabis] is genuine, and people are trying to make a difference and inviting diversity into this industry.
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For I+I's Selam Kelati, Natural Remedies Are an Ages-Old Family Tradition - CBD Today
From COVID-19 To Cancer: James Drake Discusses the Potential Health Benefits of Resveratrol – EconoTimes
Resveratrol could be the key to numerous future medical treatments.
Resveratrol is a natural polyphenol that has been suggested to benefit a myriad of health conditions: indeed, a search on the worlds largest medical journal library delivers almost 40,000 results for resveratrol. The naturally occurring compound can be found in several foods, including berries, peanuts and wine, and although its widely claimed to benefit diseases from coronavirus to cancer, there is as-yet no hard evidence to prove the benefits of the supplement.
Given the lack of hard data around resveratrol and lack of regulation, many healthcare professionals are reluctant to officially recommend it to patients, yet it remains popular as a supplementary medicine, not least for its most recent fame as a potential anti-coronavirus agent. Science philanthropist James Drake is a life-long believer in the compounds health benefits, and believes it is a valuable natural supplement, both in the fight against disease and to maintain healthy aging.
The Health Benefits of Resveratrol
Resveratrol is thought to have many pharmaceutical properties, including antioxidant, anti-aging, anti-inflammatory, anti-cancer, neuro-protective and more. While there is scant conclusive data on the exact molecular mechanisms and benefits of resveratrol on human health, there are a multitude studies showing benefit to both animals and humans. Studies have postulated a range of mechanisms of action potentially responsible for the reported benefits of resveratrol, including:
The triggering of a range of antioxidant enzymes, ultimatively leading to reduced oxidative stress
Causing overexpression of the enzyme SIRT1, which is involved in the regulation of metabolism in multiple body tissues
Inhibition of enzymes associated with neurological disorders
As a result, resveratrol has been implicated in health conditions including:
Reducing the risk or level of:
Respiratory viral infections, including COVID-19
High blood pressure
Urinary tract infections
Improving the condition of:
Skin and eye health
The immune system
Here, James Drake explores seven of the major diseases, infections, and conditions that resveratrol has been claimed to relieve or prevent and explores why the chemical compound has so much potential on the medical scene.
Some people who struggle with osteoarthritis value resveratrols anti-inflammatory properties and find that supplements can effectively reduce pain. Though the antioxidant doesnt repair damaged tissue, it is thought that it can help to prevent tissue erosion by inhibiting some cell signalling proteins that are involved in inflammation, therefore reducing articular cartilage breakdown. and serum biomarkers. One recent study found that resveratrol supplements, when taken in combination with meloxicam, can reduce pain and inflammation in patients suffering from knee osteoarthritis.
Several studies have demonstrated that resveratrols antioxidant properties reduce oxidative stress, thereby improving cognitive function, memory, and cerebral blood flow. Oxidative stress is a driver of various neurodegenerative diseases, such as Alzheimers, multiple sclerosis, and Parkinsons. James Drake, who funds a series of research studies into neurodegenerative decline, highlights that developing safe drugs to treat neurological disease is a major challenge for the medical sector, but that resveratrol could play a role in neuroprotection because of its antioxidant properties and low toxicity.
Research shows that resveratrol can have an anti-ageing effect on animals, though we dont yet know for sure whether the effects are the same for humans. To explore this, Alzheimers News Today details recent studies into resveratrols potential effects on dementias. Though there is no current conclusive evidence for resveratrols effectiveness in treating dementia, the chemical compound could become essential to future neurodegenerative treatments as research progresses.
Resveratrol has long been highlighted for its anti-cancer properties, though there are still few evidence-based human studies to support this. Animal research suggests that the chemical compound may stop cancer cells from multiplying, enhance the effectiveness of chemotherapy, and reduce the side effects of radiation. Research suggests that resveratrol could also suppress cell proliferation in human tumour cells and have further therapeutic effects on cancer patients. In particular, a study from the MD Anderson Cancer Center concludes that resveratrol can break down cancer cells in various ways to treat cervical neoplasia.
Various studies, including research from The National Institutes of Health, show that resveratrol can help to fight malaria. As a result, scientists are developing candidate vaccinations that they hope will combat the illness, which kills over one-million people around the world every year. The National Institutes of Health shows that resveratrol can significantly reduce malarias ability to adhere to blood vessels in cells. When combined with antimalarial chemotherapy, resveratrol could be key to treating the disease.
Diabetes and Metabolic Disorders
Both anecdotal and evidence-based studies have linked resveratrol with improving metabolic conditions and diabetes. For example, one such clinical trial published in 2016 investigated the effect of resveratrol on insulin resistance, glucose and lipid metabolism in non-alcoholic fatty liver disease. The study found that resveratrol supplementation may benefit patients with the disease, after seeing a marked decrease in cholesterol, glucose and other factors, and an improvement in inclusion resistance. Another study from 2017 examined the effect of resveratrol on artery stiffness in people with diabetes, finding that resveratrol supplementation correlated with a reduction in aortic stiffness in patients with particularly stiff aortas. This effect is attributed to the compounds role in activating the SIRT1 protein, and therefore slowing the effects of aging.
Respiratory Viral Infections
Many studies into the effectiveness of resveratrol focus on its antioxidant, anti-inflammatory, and anti-microbial benefits. However, a recent review from the Department of Public Health and Infectious Diseases at the University of Rome has highlighted resveratrols promising antiviral activity against viruses that cause respiratory infections. The study concludes that resveratrol could be key to preventing and treating respiratory syncytial virus, influenza virus, and SARS-CoV-2.
Amongst these respiratory viral infections, COVID-19 is the newest global threat. Over the last year, scientists and medical professionals have been grappling to develop effective coronavirus treatments. However, back in 2017, BioMed Central published a study that analysed resveratrols antiviral performance and its ability to protect against MERS-CoV, a viral pathogen that caused the MERS epidemic (and which is similar to the COVID-19-causing virus, SARS-CoV-2). The research team found that resveratrol significantly inhibits the virus and prolonged cellular survival, concluding that the natural polyphenol is a potent anti-MERS agent in vitro. Given the similarities between the viruses, its possible that resveratrol could offer some protection against SARS-CoV-2. Indeed, several research studies are already ongoing in this area.
Taking Resveratrol Supplements
The possible health benefits of resveratrol are seemingly endless, with new studies being published every week on its links with improving a multitude of conditions and diseases. However, it should be noted that resveratrol is as yet unregulated and is not prescribed by medical professional. A large amount of the existing information on resveratrol is based on animal or in vitro studies, rather than evidence-based human trials, so we do not yet know the exact benefits of the supplement, nor whether it causes any significant side effects in humans.
That being said, resveratrol is naturally abundant in food stuffs including berries, peanuts, grapes, and by extension red wine. However, the level of resveratrol in these foods is so low that we cannot absorb a therapeutic dose through dietary sources alone. James Drake has taken resveratrol supplements for many years without any known side effects. He highlights that the human body only absorbs around 10% of a supplement, which is why he takes 250 mg capsules. You can buy resveratrol from most reputable health food shops.
About James Drake
James Drake is a science-focused philanthropist who has founded multiple non-profit organisations, including The Drake Foundation and the Drake Calleja Trust. The Drake Foundation funds essential studies into the connection between repetitive head injuries obtained in sports and neurodegenerative decline. Its hoped that these studies will help to inform safe sporting protocols when it comes to head injuries and accelerate vital knowledge share in the medical space. Since its launch in 2014, The Drake Foundation has invested over 2 million into sports-related concussions research.
Meanwhile, Future Science Group (FSG) is a progressive scientific publisher, curating trusted online, print and in-person resources to serve the scientific and medical communities. Although FSGs foundation is in cutting-edge, peer-reviewed scientific journals, the Group has expanded over the years to publish digital/virtual hubs and run events, as well as creative services and publishing solutions.
When James isnt focusing his philanthropic ventures on scientific missions, his other passion lies in the arts. Among his philanthropic projects in music and art is the Drake Calleja Trust, which funds scholarships for talented young classical musicians as they aim to further their musical careers and studies.
This article does not necessarily reflect the opinions of the editors or management of EconoTimes