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- Rigenerand receives regulatory approval for gene therapy production – Cleanroom Technology
- Scientists Find A Switch To Turn Off A Gene That Causes Aggressive Breast Cancer – Forbes
- Why Editas Medicine Is Now the CRISPR Stock to Really Watch – Motley Fool
- Research Roundup: How Tau Proteins Spread in Alzheimer’s and More – BioSpace
- The Boy Slumped to the Floor. Could These Be Seizures? – The New York Times
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Carolyn Matzinger, MD Provides the Most Comprehensive Solution to Combat Fear and Effects of Covid-19 – Nevada Business Magazine
Las Vegas, NV Carolyn Matzinger, MD of Matzinger Institute of Healing (MIH), is an Internal Medicine Specialist, and leader in Cellular and Membrane/Metabolic Medicine. She has successfully treated 20,000+ patients, and is recognized for proven results in restoring total body health and improving the quality of life for patients diagnosed with various medical conditions, including: Lyme disease, Mold Toxicity, Mast Cell Activation Syndrome, Neurodegenerative disorders, Dementia, Diabetes, Cancer, Autism, Seizures and more. Facts affirm the importance of a strong immune system. During this challenging time, she is encouraging people, now more than ever, to strengthen and maintain a healthy immune system as the best defense against the effects of the Covid-19 virus.
To help boost the health of Southern Nevada residents, Dr. Matzinger has developedtheMIHImmune Support Plan, monthly treatments (for 3 months) that consist of intravenous vitamin infusions (Myers Cocktails, Vitamin C, Vitamin B12 injections) and Infrared Saunas. These treatmentsoptimize the immune system and combat a myriad of opportunistic conditions caused from a weakened immune system. Dr. Matzinger extends special discounts and incentives MIH Immune Support Plan to our Veterans, First Responders, and 55+ Communities.
With the World Health Organization declaring the Covid-19 virus a pandemic combined with the Global lock-down and social distancing mandates, the spread of the virus will slow down. However, health, political, and economic uncertainties may continue rise of fear, anxiety and stress.Dr. Matzinger stated,We must shift our focusfrom fear of uncertainties tofacts and productivity, she adds,We mustremain calm. It is a fact that increased stress and anxiety increase cortisol levels, which then leads to heightened inflammation and a weakened immune system.Stayingwell is the number one priority. Stronger than a cure are prevention and total body health (vitamin infusions, Infrared Saunas, healthy eating, appropriate supplements, Medical Lipid Colon Cleanses, regular exercise,sufficient hydration,love and laughter).
The fact remains that people with weakened immune systems are more vulnerable to the severe effects of the virus.; those over the age of 55, post- Cancer patients and individuals with pre-existing medical conditions (such as Asthma, Diabetes, Heart Disease, etc.).Thereported cases and fatalities of the virus may increase before we witness a rapid decline, andindeed a vaccine will become available.Yet, even the swiftest efforts to develop a safe vaccine, perform proper clinical trials, and manufacture an adequate supply will take at least 10 to 18 months. Nonetheless,individual immune health is important to fight off a virus, to assure inactivation of the virus in a vaccine, along with allowing the body its ability to weaken the side-effects of a vaccine.
AsDr. Matzinger leads efforts tokeep our community healthy, build solutions, and help get our lives back, it is important to recognize the following key factors that makes her practice and the MIH Immune Support Plan exceptional: MIH Immune Support Plan and all treatments are administered by a Medical Doctor; Matzinger Institute of Healing offers the most effective customized treatment plans, based on extensive nutritional and diagnostic studies.
Schedule an appointment by calling702-778-6100. MIH is located at1740 W. Horizon Ridge PKWY, Henderson, NV 89012
For more information about #MIH, visit:www.mih.vegas
About Matzinger Institute of Healing
Matzinger Institute of Healing (MIH) is a medical center with the principle idea to recreate total health by improving the immune system and decreasing inflammation. The facility utilizes the technology of Epigenetics and state-of-the-art membrane treatments with an emphasis on the gut-brain connection, and is recognized for proven results in restoring total body health and improving the quality of life for patients diagnosed with various medical conditions, including: Lyme disease, Mold Toxicity, Mast Cell Activation Syndrome, Neurodegenerative disorders, Dementia, Diabetes, Cancer, Autism, Seizures and more. All treatments are customized to each patients specific needs, and are administered by a medical doctor.
MIH is led by Carolyn Matzinger, MD, an Internal Medicine Specialist and leader in Cellular and Membrane/Metabolic Medicine, who began her medical career over 30 years ago. She has successfully treated 20,000+ patients, and is currently licensed in five states including; Nevada, California, Ohio, Idaho and Montana. Dr. Matzinger studied Lipid Therapy in Germany, and is one of the initial three Medical Doctors in the world who provides the Intensive Lipid Therapy treatments. She co-authored Audacious Aging with other professionals such as Deepak Chopra, and Andrew Weil, which won a silver medal in the Independent Publisher book awards. She is a Board Certified Physician and Diplomate of the American Board of Anti-Aging Medicine.
OPINION: Beyond the headlines: learning to recognize fake news is as important as ever – N.C. State University Technician Online
Recently, I started taking an online class through Coursera called Understanding Medical Research: Your Facebook is Wrong because it was free and I wanted to take a fun class to fill the time before Summer Session I. As I started listening to the lectures, I became aware of just how prevalent false information really is.
While some of these claims are more egregious, such as the president of the United States suggesting that injecting disinfectant into your lungs can stop the spread of the coronavirus, other claims are more hidden.
Today, about one in four adults in the U.S. gets at least some portion of their daily news from social media, and we are constantly bombarded with headlines promising a miracle cure for certain ailments, or advertising products that promote anti-aging cream or fast weight loss, which often cite various scientific studies to support their claims.
However, according to a study done this year, only a small percentage of fake-news claims ever get fact checked by social media platforms. While Im not suggesting that every study is false, it is true that studies often manipulate information to make their products sound better, which can make it difficult to discern fact from fiction.
Fortunately, social media platforms including Facebook and YouTube have taken measures to eliminate the spread of fake news; some of these platforms are providing information panels, which give more details about where the information comes from. However, sometimes it can seem much easier to skip past this extra information, especially when the headlines seem credible or plausible.
F. Perry Wilson, the instructor of the online course I previously mentioned, uses an example of the drug Lipitor, a heart medication, to illustrate the problem with taking the claims in headlines and advertisements at face value. According to the advertisement for Lipitor, the manufacturer claimed the drug had a 36% success rate. However, after absolute versus relative risk was taken into account, the actual data revealed that the drug only prevented one death out of every 100 people.
While this might seem abstract or unrelatedafter all, college students are usually not the intended audience for heart medicationstudies like these are prevalent across social media, and are often buried beneath medical jargon and statistics that have been skewed or misrepresented.
Even though it might sound tedious or unnecessary, learning terms such as relative and absolute risk as well as having a basic knowledge of statistics and medical terminology could help disseminate the spread of false information and could potentially save your life or someone elses life.
In addition to learning the terminology needed to navigate an article, it is also important to thoroughly read an article before accepting it is true, as headlines can often be misleading. Recently, hydroxychloroquine, an antimalarial drug, has received a lot of attention in the media for being a potential cure for coronavirus. According to the Association of American Physicians and Surgeons, hydroxychloroquine has about a 90% chance of helping COVID-19 patients. While I am not necessarily suggesting this study is wrong, it was conducted with a sample size of 2,333 patients, which is a relatively small sample size considering that currently over 4.2 million people across six continents have contracted COVID-19.
It is also important to double-check the headlines as well as the study itself. While I was doing research for this column, I saw an article abstract from The New England Journal of Medicine which claimed there is robust evidence to support the use of hydroxychloroquine on COVID-19 patients; however, when I read the abstract a second time, I saw that it actually said Hydroxychloroquine has been widely administered to patients with COVID-19 without robust evidence supporting its use.
While it is near impossible to completely eliminate fake or misleading information from our daily social media consumption, the ability to think critically can help us sort fact from fiction. While many of these claims may be harmless, some might have a more serious impact, and it is up to us as students, as well as citizens, to learn how to recognize false information, no matter what our first impressions might lead us to believe.
Earlier this month, 15-time Grammy winner and esteemed artist Adele wowed the world when she showed off her slimmed-down figure out of nowhere. Thankfully, her doctor shared the singers tips and tricks in order to achieve her type of weight loss in a successful and healthy way shortly after the reveal.
Adeles Doctor Reveals How Singer Lost Weight In A Healthy Way
Winning the esteemed Grammy award 15 times in her ongoing career, Adele is best known for writing songs and ballads that explore lost love, heartbreak and finding ones self after. Shes also known for her powerhouse voice, which only helps in taking her songs to new heights.
But it seems like she still has more surprises up her sleeve since the singer recently wowed everyone by unexpectedly posing a photo showing her slimmed-down figure earlier this month. Shortly afterwards, Dr. Dominique Fradin-Read, her own doctor, revealed just how the singer managed to lose all that weight. Fradin-Read is MD-board certified in preventative medicine and anti-aging medicine with a university degree in nutrition .
I start by telling my patients that when it comes to weight loss, diet and exercisealonewill not be enough in most cases. That is why many patients that come to us have tried to lose weight, they did lose somewhat but put everything back on and often even more.For a successful and sustainable weight loss, we need to look at the whole person and not just address the weight upfront, the physician said.
I combine all the tools and methods in our therapeutic arsenal, starting with the most natural approaches and lifestyle changes, vitamins/supplements, to recommending peptides, rebalancing hormones and finally prescribing medications as appropriately for each patient, she added, saying that after starting her process with the patients, she works toward more intensive treatment.
As for what to eat, Fradin-Read suggested a diet made up of nutrient-rich food as well as protein, good fats, good carbohydrates, dairy and a few wine glasses a week. Green veggies should also take around two-third of the plate. One-third should be for protein, while the remaining space should be for carbs. She also suggested following the well-known Mediterranean diet.
Obesity may occur because of genetics, family history, environment and medical conditions, among other reasons that affect body weight. Pixabay
Repurposed drug helps obese mice lose weight, improve metabolic function – National Institute on Aging
An off-label experiment in mice using disulfiram, which has been used to treat alcohol use disorder for more than 50 years, consistently normalized body weight and reversed metabolic damage in obese middle-aged mice of both sexes. The international study was led by researchers at the National Institute on Aging (NIA), part of the National Institutes of Health . The results were published online in the journal Cell Metabolism on May 14.
The scientific team studied groups of 9-month-old lab mice who had been fed a high-fat diet for 12 weeks. As expected, this diet made the mice overweight and they started to show signs of pre-diabetes-like metabolic problems, such as insulin resistance and elevated fasting blood sugar levels. Next, the scientists divided these mice into four groups to be fed four different diets for an additional 12 weeks: a standard diet alone, a high-fat diet alone, a high-fat diet with a low amount of disulfiram, or a high-fat diet with a higher amount of disulfiram. As expected, the mice who stayed on the high-fat diet alone continued to gain weight and show metabolic problems. Mice who switched to standard diet alone gradually saw their body weight, fat composition and blood sugar levels return to normal.
The mice in the remaining two groups, with either a low or high dose of disulfiram added to their still-fatty food, showed a dramatic decrease in their weight and related metabolic damage. Mice on the high disulfiram dose lost as much as 40% of their body weight in just four weeks, effectively normalizing their weight to that of obese mice who were switched back to standard diet. Mice in either disulfiram dose diet group became leaner and showed significant improvement in blood glucose levels on par with the mice who were returned to standard diet. Disulfiram treatment, which has few harmful side effects in humans, also appeared to protect the pancreas and liver from damage caused by pre-diabetic type metabolic changes and fat build up usually caused by eating a high-fat diet.
The NIA scientists, Michel Bernier, Ph.D., and Rafael de Cabo, Ph.D., collaborate frequently with researchers at NIH and beyond on studies into how changes in dietary patterns like intermittent fasting could lead to cognitive and physical health benefits. They first became interested in disulfiram after reading about the benefits this class of drug has shown in treating type 2 diabetes in rats, coupled with the growing interest in repurposing drugs that may also improve healthy aging.
When we first went down this path, we did not know what to expect, but once we started to see data showing dramatic weight loss and leaner body mass in the mice, we turned to each other and couldnt quite believe our eyes, Bernier said.
According to studys research team, the key to the positive results seem to stem from disulfirams anti-inflammatory properties, which helped the mice avoid imbalances in fasting glucose and protected them from the damage of fatty diet and weight gain while improving metabolic efficiency. Both groups of obese mice (control and disulfiram) were not subjected to any form of exercise, nor did they demonstrate noticeable spontaneous behavioral changes. Based on the evidence they observed, the researchers believe the beneficial results of disulfiram stem solely from the drug. They did not observe any negative side effects from disulfiram in the mice.
The research team stresses that these results are based on animal studies, and they cannot be extrapolated to any potential benefits for human at this point. It is recommended that disulfiram not be used off-label for weight management outside of the context of clinical trials. Still, given the findings, they are planning future steps for studying disulfirams potential, including a controlled clinical study to test if it could help individuals with morbid obesity lose weight, as well as deeper investigation into the drugs molecular mechanisms and potential for combining with other therapeutic interventions.
The research was supported by NIA through its intramural research program, NIA grants AG031782 and AG038072, in collaboration with colleagues from the National Institute of Alcohol Abuse and Alcoholism, Yale University, Albert Einstein College of Medicine, Korea Research Institute of Bioscience and Biotechnology, and University of Sydney, Australia.
This press release describes a basic research finding. Basic research increases our understanding of human behavior and biology, which is foundational to advancing new and better ways to prevent, diagnose and treat disease. Science is an unpredictable and incremental process each research advance builds on past discoveries, often in unexpected ways. Most clinical advances would not be possible without the knowledge of fundamental basic research.
Bernier et al. Disulfiram prevents and treats diet-induced obesity and related co-morbidities in mice. Cell Metabolism. 2020 May 14. doi: /10.1016/j.cmet.2020.04.019
About the National Institute on Aging (NIA): NIA leads the U.S. federal government effort to conduct and support research on aging and the health and well-being of older people. Learn more about age-related cognitive change and neurodegenerative diseases via NIAs Alzheimer's and related Dementias Education and Referral (ADEAR) Center website. For information about a broad range of aging topics, visit the main NIA website and stay connected.
About the National Institute on Alcohol Abuse and Alcoholism (NIAAA): The National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health, is the primary U.S. agency for conducting and supporting research on the causes, consequences, diagnosis, prevention, and treatment of alcohol use disorder. NIAAA also disseminates research findings to general, professional, and academic audiences. Additional alcohol research information and publications are available at https://www.niaaa.nih.gov/.
About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit https://www.nih.gov/.
NIH...Turning Discovery Into Health
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Repurposed drug helps obese mice lose weight, improve metabolic function - National Institute on Aging
Although scientists and stock markets have celebrated the approval for emergency use of remdesivir to treat COVID-19, a cure for the disease that has killed nearly 260,000 people remains a long way off and might never arrive.
Hundreds of drugs are being studied around the world, but I dont see a lot of home runs right now, said Dr. Carlos del Rio, a professor of infectious diseases at the Emory University Rollins School of Public Health. I see a lot of strikeouts.
Researchers have launched more than 1,250 studies of COVID-19. Pharmaceutical companies are investing billions to develop effective drugs and vaccines to help end the pandemic.
Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, was cautious when announcing the results of a clinical trial of remdesivir last week, noting it isnt a knockout. Although remdesivir helped hospitalized COVID-19 patients recover more quickly, it hasnt been proved to save lives.
This [drug] is opening the door, Fauci said. As more companies and investors get involved, its going to get better and better.
Researchers have already announced that they will combine remdesivir with an anti-inflammatory drug, baricitinib now used to treat rheumatoid arthritis in the hope of improving results.
But COVID-19 is an elusive enemy.
Doctors treating COVID patients say theyre fighting a war on multiple fronts, battling a virus that batters organs throughout the body, causes killer blood clots and prompts an immune system overreaction called a cytokine storm.
With so many parts of the body under siege at once, scientists say, improving survival rates will require multiple routes of attack and more than one drug. While some of the experimental medications target the virus, others aim to prevent the immune system from inflicting collateral damage.
There are so many pieces of this, and they will all require different therapies, said Dr. Lewis Kaplan, president of the Society of Critical Care Medicine, whose doctors provide intensive care.
High-tech approaches include using stem cells, virus-specific T cells and synthetic antibodies to neutralize the coronavirus.
Scientists are also taking a fresh look at existing medications that might be repurposed to fight COVID-19. These include antivirals for influenza, arthritis drugs, estrogen patches and even antacids. If repurposed drugs are successful, they could reach patients relatively quickly, because doctors are already familiar with their side effects and safety concerns.
Some doctors are skeptical that drugs for heartburn or hot flashes have any chance of treating a killer like COVID-19.
Dr. Steven Nissen, chair of cardiovascular medicine at the Cleveland Clinic, said he fears that hype over unproven products will harm patients, even if it temporarily boosts company stock prices. Patients who demand antacids or antimalarial drugs being studied in COVID-19 could be harmed by side effects, for example. Those who hoard drugs on the hope of protecting themselves from COVID-19 could deprive other patients of medications they need to stay healthy. Some people may refuse to participate in clinical trials because they fear being given a placebo.
This rush to get every imaginable treatment into a study, its not prudent, Nissen said. Its not good medicine. Its an act of desperation.
Other experts say scientists should cast a wide net.
I dont think we want to rule anything out because it sounds out of the ordinary, said Dr. Walid Gellad, director of the Center for Pharmaceutical Policy and Prescribing at the University of Pittsburgh.
Antivirals In The Spotlight
Antivirals such as remdesivir aim to prevent viruses from replicating, said Dr. Peter Hotez, a professor at Baylor College of Medicine in Houston.
That doesnt always work. A small Chinese study of remdesivir, published last month in The Lancet, found no benefit to severely ill COVID-19 patients. Remdesivir had previously failed when tested against Ebola.
Antivirals tend to be most helpful in the early stages of infection, when most of the harm to the patient is caused by the virus itself, rather than the immune system, Hotez said.
Remdesivir is just one of many antivirals being tested against COVID-19.
International researchers are studying the antiviral favipiravir, developed to fight the flu.
The antimalarial drugs chloroquine and hydroxychloroquine which have been heavily touted by President Donald Trump also have antiviral effects. Although the Food and Drug Administration approved forms of those drugs for emergency use against COVID-19, the agency later warned that they could cause dangerous heart rhythm problems.
A study in the New England Journal of Medicine likewise found no benefit in giving two antivirals used to treat HIV a combination of lopinavir and ritonavir, sold as Kaletra in adults hospitalized with severe COVID-19.
Harnessing The Immune System
One of the therapies generating excitement is also one of the oldest: antibody-rich blood from COVID survivors.
The immune system produces antibodies in response to invaders such as viruses and bacteria, allowing the body to recognize and neutralize them. Antibodies also recognize and neutralize the virus the next time that person is exposed.
Doctors hope that patients who develop antibodies against the novel coronavirus will become immune, at least for a few years, although this hasnt been proved.
Scientists developing this convalescent plasma are studying whether COVID-19 survivors can share this immunity with others by donating their plasma, the liquid part of blood that contains antibodies, said Dr. Shmuel Shoham, an associate professor of medicine at the Johns Hopkins University School of Medicine.
In addition to treating people who are already sick, donated plasma could potentially prevent people exposed to the virus such as health care workers from developing symptoms.
Donated antibodies and any immunity they might provide dont last forever, said Dr. William Schaffner, a professor at the Vanderbilt University Medical Center. The body destroys aging antibodies as part of its routine maintenance, he said. In general, half of donated antibodies are eliminated in about three weeks.
The use of convalescent plasma goes back more than a century. It was used during the 1918 flu pandemic and was shown to improve survival during the 2009-10 H1N1 pandemic.
Doctors dont know yet whether convalescent plasma will benefit people with COVID-19.
In general, convalescent plasma is expected to be more effective in preventing illness than in treating it. It may be less likely to help someone in intensive care, Shoham said.
Researchers are also studying the use of prepackaged plasma, called intravenous immunoglobulin, in COVID patients. This product, known as IVIG, is taken from healthy donors in the general population and has long been used to help patients with weakened immune systems fight off infections. Hospitals keep it in stock and some are already using it to treat COVID patients.
Although the antibodies in prepackaged IVIG dont specifically target the coronavirus, researchers hope they will tamp down the immune response.
In a third form of immune therapy, researchers are trying to identify the specific antibodies that are most important for neutralizing the coronavirus, then reproduce them as drugs called monoclonal antibodies. Monoclonal antibodies are already used to treat a variety of conditions, from cancer to rheumatoid arthritis and migraines.
When we give people an antibody, they are immediately at least partially immune to that specific virus, said Dr. James Crowe, director of the Vanderbilt Vaccine Center, who hopes to have antibodies ready for a clinical trial in a few months. Were moving the immune system from one person to another.
Ideally, doctors would develop a very potent monoclonal antibody or a cocktail of antibodies for COVID-19 patients, to ensure the best chance of success, Crowe said. But manufacturing these drugs can be complicated, expensive and time-consuming.
Making two antibodies would be at least twice as complicated as making one, Crowe said. A cocktail might be preferred, but cocktails are harder to move quickly.
Calming The Immune System
In most cases of COVID-19, the immune system neutralizes the coronavirus and patients recover without going to the hospital.
For reasons that doctors dont totally understand, the immune system of some COVID-19 patients becomes hyperactive, attacking not just the virus but the patients own cells. A cytokine storm, in which the immune system floods the body with inflammatory chemicals, can do more damage than the virus itself.
In an effort to calm the immune system, researchers are testing immune-suppressing drugs, including monoclonal antibodies already used to treat autoimmune diseases such as rheumatoid arthritis, said Dr. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security.
Health care giant Roche is conducting large clinical trials of its drug, Actemra, in the hope of preventing cytokine storms, which can cause organ failure and a life-threatening condition called sepsis. Actemra is designed to lower levels of an inflammatory chemical, interleukin-6, which has been found to be elevated in some COVID-19 patients.
Scientists are also studying similar drugs, anakinra and siltuximab.
Another immune suppressant from Regeneron and Sanofi, called Kevzara, has had disappointing results in clinical trials. The manufacturers plan to continue studying the drug to see if it can help certain types of patients.
Dr. Anar Yukhayev, a New York OB-GYN who was hospitalized with COVID-19 on March 16, agreed to join a clinical trial of Kevzara.
I was having so much trouble breathing that I was desperate for anything to help, said Yukhayev, 31, who was treated at Long Island Jewish Medical Center.
About 36 hours after receiving an infusion, as Yukhayev was being treated in intensive care, his symptoms began to improve. He was able to avoid being put on a ventilator. Doctors didnt tell him if he received Kevzara or a placebo, but his liver enzymes also began to rise, suggesting the organ was under stress. Elevated liver enzymes are a known side effect of Kevzara.
Yukhayev made a full recovery and went back to work full time April 13. He donated his plasma to researchers.
Until vaccines and other preventive medicines are developed, the best way to prevent coronavirus infections is to maintain social distancing, Adalja said.
Social distancing is a blunt tool, he said, but its all that we have.
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Chasing The Elusive Dream Of A COVID Cure - Kaiser Health News
Medicinal mushrooms are spreading rapidly through the health and wellness world, popping up in protein powders, teas, and supplements at every local health food store.
So, what are medicinal mushrooms? Are they safe? What health benefits are they supposed to have?
First off, medicinal mushrooms are part of ancient, traditional medicine going back thousands of years. These incredible fungi are known for almost every health benefit under the moon including fighting inflammation, boosting energy, decreasing anxiety, preventing cancer, and even getting you a great nights sleep.
Yet, the one thing that most medicinal mushrooms share in common is their ability to support, maintain, and boost the immune system! In these somewhat chaotic and uncertain times, everyone could use a little boost to their immune system.
Plus, due to their growing popularity, medicinal mushrooms are available in a variety of forms including powders, extracts, tinctures, and teas, meaning you can integrate these wonderful natural medicines into your life in any way you feel comfortable.
Medicinal mushrooms have been on the scene for thousands of years.
Edible medicinal mushrooms are part of traditional Chinese medicineand have been used for health promotion and longevity in China and other East Asian countries for centuries. In fact, Ganoderma a very specific medicinal mushroom has been used as an herbal remedyas far back as 2000 years.
So, what makes these fungi so great?
While research is still ongoing regarding the exact mechanism that makes this plant-based medicine tick, structural andpharmacological studies revealed that fungal glycans show multiple physiological and healthy promoting effects including immunomodulation, anti-tumor, anti-aging, anti-oxidation, hypoglycemic, hypolipidemic, anti-radiation, and other effects.
With that said, each mushroom has a unique set of beneficial properties. Knowing the profile of each medicinal mushroom is instrumental when choosing the appropriate single fungi or multiple mushroom mix to tackle your personal health goals!
On that note, what exactly are the most popular medicinal mushrooms? What do they offer? How do you consume them? Where can you find them?
Lots of great questions and Ive got all your answers!
First and foremost, before launching into the world of medicinal mushrooms, its important to outline your own personal health goals. Ask yourself why youre seeking a medicinal aid? Once youve got some goals outlined and clarified, take a deep dive into the following medicinal mushrooms to find the perfect single or mixture!
Familiar to the medicinal practices in Siberia, Russia, Northern European countries, and other parts of Asia, Chaga mushroom has been used for a variety of health benefits and ailments including boosting immunity and improving overall health.
With that said, this mushroom cant really be classified as attractive. Chaga forms into a woody growth, or conk, which looks similar to a clump of burnt charcoal roughly 10-15 inches (25-38 centimeters) in size, yet inside youll discover a soft core with an orange color.
Known as an antioxidant powerhouse, Chaga mushrooms are excellent for fighting free radicals and inflammation. Various studies have shown this mushroom to be effective at combating oxidated stress, linked to skin aging slowing the growth of cancer, and it has also been found to lower low-density lipoprotein LDL, the bad cholesterol. This is why Chaga mushroom is best used to fight the signs of aging, reduce inflammation, and help manage cholesterol.
Unfortunately, there arent any human studies that have determined Chagas safety or appropriate dosage, therefore its up to the consumer to find a reputable supplement company, as well as speak with a medical professional before consuming the product. While Chaga is generally safe, its been known to interact with some common medications, causing potentially harmful effects, such as those taking insulin for diabetes, those taking blood-thinning medications, or those suffering from autoimmune diseases.
If youre looking to get your hands on some of that good old Chaga mushroom, here are a few easy options:this Sayan Siberian Wild Forest Chaga Mushroom Extract Powder Supplement, this Host Defense Chaga Capsules, or this NordicNordic Chaga Mushroom Tea.
When it comes to cordyceps, you have both the soil and insects to thank!
This parasitic fungi grows on the larvae of insects. How does it work? The fungi actually attack their host and replaces its tissue with long, slender stems that grow outside the hosts body. What youre left with are the remains of the insect and fungi which are hand-collected, dried and have been used in Traditional Chinese Medicine for centuries.
Of course, theres not justone typeof cordyceps. In fact, there are over 400 species of Cordyceps discovered, yet two specific varieties have become the focus of health research: Cordyceps sinensisandCordyceps militaris.
While cordyceps have been used for thousands of years to treat a myriad of ailments including fatigue, sickness, kidney disease, and low sex drive modern-day herbal practitioners generally source cordyceps to boost energy, athletic performance, and muscle recovery. Basically, cordyceps are a one-stop-shop for those beginning or uber athletes!
Turns outCordyceps sinesisis particularly difficult to harvest and carries a price tag of more than $9,000 USD per pound, which means that most of these mushrooms are actually synthetically grown. Youll want to look for brands that carry the United States Pharmacopeia (USP) or NSF International (NSF) seal, referring to third-party organizations that weed out impurities and verify ingredients.
More research is needed to verify dosages, yet the most commonly used reference range is between 1,000 [to] 3,000 mg per day which has been associated with side effects and has been found to have certain health benefits.
Cordyceps are best consumed in powder or supplement form. Here are a few vegan-friendly, online options: this Four Sigmatic Cordyceps Mushroom Elixir, this Micro Ingredients Sustainably US Grown Organic Cordyceps Mushroom Powder, or this NOW Foods Cordyceps Supplements.
Lions mane mushrooms go by many traditional names includinghou tou gu and yamabushitakeand have been used far and wide in both culinary and medicinal practices in countries including China, India, Japan, and Korea.In its natural, unadulterated form, the lions mane mushroom is large, white, and shaggy, resembling a lions mane as they grow, hence the Westernized name.As a medicinal aid, lions mane is generally dried and used as an extract in a powder form. When it comes to cooking, this meaty mushroom is a great seafood replacement, oftentimes compared to crab or lobster.
Lions mane is particularly special in that it produces bioprotein nerve growth factor (NFG) and myelin (insulation around nerve fibers), both of which are crucial to brain health. Along with being a wonderful brain-boosting agent, lions mane is linked to increased concentration and memory, better cognition, and even a decreased level of anxiety and irritability (most likely from all those brain-boosting effects!).
While there arent any human studies conducted on lions mane, its generally considered to be a safe food to consume with the guidance of a healthcare professional. With that said, if youre allergic or sensitive to mushrooms you should absolutely avoid lions mane.
Lions mane may look a bit scary in its natural form, yet luckily theres lovely processed forms that make this much more manageable! Try out this Host Defense Lions Mane Capsules, this Four Sigmatic Lions Mane Mushroom Elixir, or this Micro Ingredients Sustainably US Grown Organic Lions Mane Mushroom Powder.
One of the more widely-recognized and popular medicinal mushrooms, reishi also happens to be one of the more affordable and easily accessible!
Also known as Ganoderma lucidum and lingzhi, reishi mushroom is a fungus that grows in various hot and humid locations in Asia. Reishi is a wonderful medicinal agent due to several molecules, includingtriterpenoids, polysaccharides, and peptidoglycans, that may be responsible for its health effects. This medicinal mushroom happens to be one of the varieties safely eaten raw, yet powdered forms are more widely used.
Reishi is well-known for its calming properties all of which are thanks to the compound triterpene, which reishi has its fair share of. This mushroom is known to aid sleep, decrease symptoms of anxiety and depression, and can even increase focus. On top of that, reishi has been known to promote healing.
There are great reasons to get on board with reishi mushroom, yet there are also some safety concerns to consider and go over with your doctor beforehand.
First and foremost, studies have shown that reishi mushroom consumption may cause upset stomach or digestive distress and two case studies, in particular, found significant liver problems after switching to the powdered form of reishi mushroom. This leaves some dangling questions regarding the effect of reishi mushroom on the liver, whether theres something off with the powdered form of reishi or whether it was a specific instance to this study.
With the limited data available, its recommended that those who are pregnant or breastfeeding, have a blood disorder, will be undergoing surgery or have low blood pressure should probably avoid reishi mushroom consumption.
Reishi is super popular in powder form, such as this Micro Ingredients Sustainably US Grown Organic Reishi Mushroom Powder. Yet, if youre a little weary of the powder, you can always try a good old supplement such as this New Chapter Reishi Mushroom Supplement or this BoostCeuticals Reishi Mushroom Capsules.
Shiitake mushrooms happen to be uber popular in fact, they are one of the most popular mushrooms worldwide. Along with offering some great health benefits, shiitake also have a wonderful savory flavor.
Shiitake mushrooms are native to East Asia and are found growing naturally on decaying hardwood trees. Most shiitake mushrooms are sourced from Japan around 83 [percent] in fact yet theyre also grown in the United States, Canada, Singapore, and China. In their natural state, they are tan to dark brown, with caps that grow between 2 and 4 inches (5 and 10 cm). While theyre most popularly consumed raw, you can also find shiitake mushrooms in powder and extract forms.
This particular medicinal mushroom is one of the few that has a full nutrition profile offering fiber, protein, vitamins, riboflavin, niacin, folate, B5, B6, and D and minerals copper, selenium, manganese, and zinc.
Plus, theyre also linked to a myriad of health benefits including boosting heart health, lowering cholesterol, improving blood pressure, increasing circulation, and boosting immunity. Shiitake is particularly nifty for preventing plaque buildup.
Shiitake mushroom is generally recognized as safe to consume, as long as you dont have a food allergy to fungi or mushrooms in particular. For instance, in a few rare cases, people have developed a skin rash from eating or handling raw shiitake, referred to as shiitake dermatitis and is caused by lentinan. On top of that, some observational studies have found that long-term use of the powdered form of shiitake has led to stomach upset and sensitivity to light.
While you can definitely pick up some shiitake at your local grocery store to cook for dinner or even pick up a shiitake-based ingredient such as this Edward & Sons Roads End Organics Gluten-Free Vegan Shiitake Mushroom Gravy Mix, an easier on-the-go option would be either powder or supplements, such as this Gaia Herbs Mushrooms + Herbs Reishi + Turmeric Supplement or this New Chapter Reishi Mushroom Supplement.
Personally, this one has the best of the names, yet dont let this silly title dissuade you from its serious health benefits!
Turkey Tail also goes by Trametes versicolor and versicolor,yet gets its more friendly name due to its striking colors. This is yet another super popular medicinal aid, having been used to treat various conditions for centuries. One of the most recognized qualities of turkey tail is its immune-boosting powers!
Turkey tail contains a compound called polysaccharide-K (PSK) that stimulates the immune system. This compound is also an effective cancer-fighting agent and has been found to improve the immune system of people receiving chemotherapy. This mushroom also contains high amounts of antioxidants, lending to its cancer-preventing and immune-boosting properties.
While turkey tail is considered safe, some people have experienced digestive symptoms like gas, bloating, and dark stools when taking turkey tail mushroom. On top of that, another potential side effect of consuming turkey tail mushroom is the darkening of the fingernails. Very strange, but its a documented side effect!
As is the same with any other medicinal mushroom, always speak with your healthcare provider before beginning consumption!
Get some that wonderful immune boosting turkey tail in your life with this Turkey Tail Sustainably US Grown Organic Turkey Tail Mushroom Powder, this Double Wood Turkey Tail Mushroom Supplement, or this Wild Foods Turkey Tail Mushroom Extract Powder.
Golden Chaga Latte/One Green Planet
Alright, so youve selected youre favorite medicinal mushroom or mix of medicinal mushrooms! and now you want to get down and dirty with infusing your body with all of their goodness. While its super easy to simply add a spoonful to a flavorful smoothie or shake, its also just as easy to create a medicinal mushroom-based meal. Whether you want to use the whole mushroom such as shiitake or lions mane or want to stick with the non-cook powder, theres options out there for everyone!
Comforting Shiitake and Kale Congee/One Green Planet
Shiitake is one of the most popular and easiest of the medicinal mushrooms to use in plant-based recipes. Its one of the more affordable options and is generally available at your local grocery store. Plus, there are lots of ways to get this wonderful medicinal mushroom into your cooking! This Comforting Shiitake and Kale Congee recipe by Annie Oliviero is exactly that, comforting. Warm, savory, and super-nutritious, this recipe is not only filled with medicinal agents to help lower cholesterol, boost heart health, regulate blood pressure, and increase circulation, you also get a dose of detoxing and healing garlic and ginger to boost that immunity.
Chocolate Reishi Latte/One Green Planet
Next to the popularity of shiitake mushrooms, reishi is climbing the ranks in the Western world! This may be due to higher rates of anxiety and depression in these modern times or it could also be attributed to more awareness of self-care and wellness. No matter the reason, reishi is definitely a hot commodity! When it comes to cooking with reishi mushroom, try your hand at the powdered version such as in this Chocolate Reishi Latte recipe by Maria and Alyssa Tosoni. Along with a teaspoon of reishi powder to help with sleep, anxiety, depression, and focus this recipe calls for detoxing raw cacao powder and inflammation-fighting cinnamon, creating a concoction to calm and heal!
No-Bake Chaga Maca Cookie Bites/One Green Planet
As mentioned, Chaga is known as one of the best medicinal mushrooms to help fight premature aging, reduce inflammation, and even helps to lower bad LDL cholesterol. Its also a great ingredient to cook with! While you may think youre stuck with hot beverages, shakes, and smoothies when it comes to using mushroom powder, you can actually include a teaspoon here and there in any of your favorite super flavorful recipes. This No-Bake Chaga Maca Cookie Bites recipe by Crystal Bonnet creates a wonderful treat thats great to have on hand! Not only does it source those medicinal powers from a teaspoon of Chaga mushroom powder, but its also rich in healing and anti-inflammatory maca powder and cacao powder (and nibs!).
Reducing your meat intake and eating more plant-based foods is known to help withchronic inflammation,heart health,mental wellbeing,fitness goals,nutritional needs,allergies,gut healthandmore!Dairy consumption also has been linked to many health problems, includingacne,hormonal imbalance,cancer,prostate cancerand has manyside effects.
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