Category Archives: Anti-Aging Medicine

The mild weather days are nice to enjoy, but we all know real winter cold isn't too far awayNews / 10 hours ago

The forecast this week is showing another round of very mild weather moving into KELOLANDNews / 1 day ago

The warm weather this week is a continuation of the temperatures earlier this monthNews / 2 days ago

KELOLAND Live Doppler HD Storm Center Winter Weather Special 2020News / 6 days ago

Weather outlook: Temperature swings throughout month of NovemberNews / 5 days ago

Our already chilly nights have become a little bit colder latelyNews / 6 days ago

Winter gave a nice looking landscape to southeast KELOLAND this morningNews / 1 week ago

Taking a look at last week's record high tempsNews / 1 week ago

Warm first week of November breaks over 100-year recordNews / 2 weeks ago

Much colder air arrives next weekNews / 2 weeks ago

Another prolonged stretch of dry weather will stick around in KELOLANDNews / 2 weeks ago

Warm weather in the forecast could set new recordsNews / 2 weeks ago

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Rally in support of mask mandate and Sioux Falls medical workers - KELOLAND.com

Synchron recently announced the publication of a first-in-human study demonstrating the successful use of their device called Stentrode which is a brain-computer interface neuroprosthesis. The brain implant that is inserted in the jugular allows ALS patients to type with their minds.

Synchrons CEO, Thomas Oxley, MD, Ph.D., describes the implant as Bluetooth for the brain. The big difference between what we have done with what previous approaches have done is that we do not put any needles into the brain or on top of the brain. The device stays inside the blood vessel.

The study findings published in the Journal of NeuroInterventions Surgery specifically show the devices ability to enable patients with severe paralysis to resume daily tasks such as texting, emailing, shopping and banking online all through direct though without the need for open brain surgery.

This study is the first to demonstrate that a BCI that has been transplanted via patient blood vessels is able to restore the transmission of brain impulses out of the body wirelessly; patients successfully used their impulses to control digital devices without using a touchscreen, mouse, keyboard or voice-activated technology.

This is a breakthrough moment for the field of brain-computer interfaces. We are excited to report that we have delivered a fully implantable, take home, wireless technology that does not require open brain surgery, which functions to restore freedoms for people with severe disability, said Thomas Oxley MD Ph.D., founding CEO, Synchron. Seeing these first heroic patients resume important daily tasks that had become impossible, such as using personal devices to connect with loved ones, confirms our belief that the Stentrode will one day be able to help millions of people with paralysis.

Using the Stentrode neuroprosthesis device patients controlled the Microsoft Windows 10 operating system, in combination with an eye tracker for cursor navigation without a mouse or keyboard. Patients undertook machine learning assisted training to control multiple mouse click actions, and the first 2 patients were able to achieve an average click accuracy of 92 and 93% with typing speeds of 14 and 20 characters per minute with predictive text disabled. The device was used to resume daily tasks independently following implantation and training to commence unsupervised home use of the system from day 86 and 71.

Using the Stentrode has been life-altering, said Graham Felstead, the first patient enrolled in the first Stentrode clinical study and the first person to have any BCI implanted via the blood vessels. The device has allowed me to be productive again, including shopping, banking, and delegating tasks among the Rotary Club members with whom I volunteer. Its incredible to gain this level of independence back. By using the Stentrode, Graham was able to achieve his goals of remotely contacting his spouse, increasing his autonomy and reducing her burden of care. He was able to maintain contact with other family members, medical professionals and people in his community. Graham, a 75-year-old man living at home with his wife, has experienced severe paralysis due to amyotrophic lateral sclerosis (ALS), and received the Stentrode implant in August 2019. He continues to use it today.

It is truly amazing, and very rewarding, to see the participants use the Stentrode to control a computer with their minds, independently and at home, said Nicholas Opie, associate professor and co-head of the vascular bionics laboratory at the University of Melbourne and founding CTO of Synchron. The trial participants have been fantastic, and my colleagues and I are truly honored to make a difference in their lives. I hope others are inspired by their success.

The second participant, Philip OKeefe, a 60-year-old man with ALS, working part-time and living at home with his wife and two children, was able to control computer devices to conduct work-related tasks and other independent activities after receiving the Stentrode in April 2020. Functional impairment to his fingers, elbows, and shoulders had previously inhibited his ability to engage in these efforts.

While the Stentrode is a completely novel concept and design, the procedure to implant it draws upon techniques that I use on a daily basis and which have become routine in our industry. The Stentrode technology exemplifies the progress and potential of neurointervention departments to deliver new therapies to patients, said Professor Peter Mitchell, Director of Neurointervention, The Royal Melbourne Hospital, a pioneering neurointerventionalist who performed the first clinical implantations of the Stentrode device. The intricacies of the brain have always fascinated me and enabling a patient with paralysis to continue to use their mind in a productive way is immensely rewarding.

This device is small and flexible enough to safely pass through curving blood vessels, the implantation procedures are similar to that of a pacemaker and does not require open brain surgery. This may reduce the risk of brain tissue inflammation and rejection of the device which has been an issue for devices in the past using techniques that require direct brain penetration.

The device is delivered into the jugular vein, using a catheter to thread the device upward until it is adjacent to the motor cortex. Once implanted the device is able to pick up nearby brain activity using tiny electrodes that dot its surface. A second device embedded into the patients chest transmits data wirelessly to a computer or other smart device that is running the machine learning software which in turn converts that information into computer commands and functions.

Other approaches to brain-computer interfaces have been focused on high data rates, which create technical barriers to clinical translation. Synchron has focused on building a product that measurably improves patients lives. Our first-to-market product will focus on smart device control using brain impulses, without the need for the use of the hands. This alone has potential to address an unmet market need in 30 million patients in advanced economies, added Oxley.

The US FDA granted Stentrode Breakthrough Device designation, and the safety and efficacy data from this feasibility study will be used to finalize the protocols for a future FDA approval trial that will eventually guide the evaluation of the device for American marketing approval.

The neurovascular bioelectronic medicine company presented preliminary data on the first patient at the Society of NeuroInterventional Surgery Annual Meeting In August 2020, and the long term safety as well as ability to pick up specific electrical frequencies emitted by the brain was established by preclinical studies that were published in Nature Biotechnology, Nature Biomedical Engineering and the Journal of Neurosurgery.

Eventually, the company plans to use this technology to help paralyzed patients control robotic limbs in order to provide them even more freedom and have an even bigger positive impact on the everyday lives of people who use it.

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Device Reads Paralyzed People's Thought Through Their Veins - Anti Aging News

Dublin, Nov. 13, 2020 (GLOBE NEWSWIRE) -- The "Global Aesthetic Filler Market 2019-2028" report has been added to ResearchAndMarkets.com's offering.

According to this research report, the global market for aesthetic filler is expected to surge at a CAGR of 10.35% during the evaluated period of 2019-2028.

The growing demand for aesthetic fillers, a surge in healthcare expenditure, rising acceptance of tissue fillers, and a growing aging population are significant factors that augment the aesthetic filler market's progression worldwide. Additionally, the increasing number of men undergoing cosmetic procedures, along with growing awareness about cosmetic procedures, are creating multiple opportunities for the market's future.

However, the negative effect of unregistered practitioners, paired with the high cost of procedures, are significantly weighing down the aesthetic filler market.

The global aesthetic filler market covers the Asia-Pacific, Europe, North America, Latin America, and the Middle East and Africa regions.

The Asia-Pacific is expected to become the fastest-evolving market for aesthetic filler over the estimated period 2019-2028. In China, the younger population is mainly persuaded by westernized looks, which leads them to undergo cosmetic procedures. Among the various procedures, facelift and eyelid surgery, are the most common cosmetic procedures. Additionally, China has the highest number of cosmetic procedures, with growing male customers. The people between 20 and 40 are undergoing cosmetic surgeries, which is enhancing the demand for facial surgeries. This further augments the aesthetic filler market in China, thereby overall APAC region.

The key enterprises involved in the aesthetic filler market are Galderma Pharma SA, Laboratoires Vivacy SAS, Sculpt Luxury Dermal Fillers Ltd, Zhejiang Jingjia Medical Technology Co Ltd, Suneva Medical Inc, Teoxane, Bioxis Pharmaceuticals, Contura Ltd, Prollenium Medical Technologies, Anika Therapeutics Inc, Bioha Laboratories, Allergan, Merz Pharma, Sinclair Pharma, and Ipsen.

Allergen is a global pharmaceutical company that concentrates on manufacturing, and commercializing branded regenerative medicine, pharmaceutical device, surgical, and biologic products for patients. Its product portfolio comprises products for medical aesthetics and dermatology, women's health, and eye care, among others. The company has its headquarter in Ireland, with its operation across all regions.

Key Topics Covered:

1. Global Aesthetic Filler Market - Summary

2. Industry Outlook2.1. Market Definition2.2. Key Insights2.2.1. Increased Awareness About Anti-Aging Measures2.2.2. Increasing Popularity of Minimally Invasive and Non-Invasive Procedures2.3. Impact of COVID-19 on Aesthetic Filler Market2.4. Porter's Five Forces Analysis2.4.1. Threat of New Entrants2.4.2. Threat of Substitute2.4.3. Bargaining Power of Buyers2.4.4. Bargaining Power of Suppliers2.4.5. Threat of Competitive Rivalry2.5. Market Attractiveness Index2.6. Vendor Scorecard2.7. Market Drivers2.7.1. Growing Demand for Facial Aesthetics2.7.2. Rising Acceptance of Tissue Fillers2.7.3. Increasing Aging Population2.7.4. Increase in Healthcare Spending2.8. Market Restraints2.8.1. Negative Effect of Unregistered Practitioners2.8.2. High Cost of Procedure2.9. Market Opportunities2.9.1. Increasing Number of Men Undergoing Cosmetic Procedures and Awareness About Cosmetic Procedures2.9.2. Increase in Beauty Consciousness and Disposable Income2.9.3. Advancements in Facial Rejuvenation2.10. Market Challenges2.10.1. Challenges Arising from Reimbursement Issues, Social Stigma, and Rapidly Advancing Technologies2.10.2. Side Effects Associated with Dermal Fillers

3. Global Aesthetic Filler Market Outlook - by Product Type3.1. Wrinkle Relaxers3.2. Dermal Fillers3.2.1. Collagen3.2.2. Hyaluronic Acid3.2.3. Fat Injection3.2.4. Polylactic Acid3.2.5. Polymethyl Methacrylate Microspheres (Pmma)3.2.6. Calcium Hydroxylapatite

4. Global Aesthetic Filler Market Outlook - by Application4.1. Facial Line Correction4.2. Lip Treatment4.3. Face Lift4.4. Acne Scar Treatment4.5. Lipoatrophy Treatment4.6. Others

5. Global Aesthetic Filler Market - Regional Outlook5.1. North America5.2. Europe5.3. Asia-Pacific5.4. Latin America5.5. Middle East and Africa

6. Competitive Landscape6.1. Allergan (Acquired by Abbvie)6.2. Galderma Pharma Sa (Acquired by Eqt)6.3. Laboratoires Vivacy Sas6.4. Merz Pharma6.5. Sinclair Pharma6.6. Suneva Medical Inc6.7. Teoxane6.8. Anika Therapeutics Inc6.9. Bioha Laboratories6.10. Bioxis Pharmaceuticals6.11. Contura Ltd6.12. Prollenium Medical Technologies6.13. Zhejiang Jingjia Medical Technology Co Ltd6.14. Sculpt Luxury Dermal Fillers Ltd6.15. Ipsen

7. Methodology & Scope

For more information about this report visit https://www.researchandmarkets.com/r/v0qj9e

Research and Markets also offers Custom Research services providing focused, comprehensive and tailored research.

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The Worldwide Industry for Aesthetic Fillers is Expected to Grow at a CAGR of 10.35% Between 2019 and 2028 - GlobeNewswire

Gopesh Patel, RPh, of VLS Pharmacy in Brooklyn, New York, and New Drug Loft in New York City, has been named PCCAs 2020 M. George Webber, PhD, Compounding Pharmacist of the Year.Photo Credit: New Drug Loft

Professional Compounding Centers of America (PCCA) named Indian-American Gopesh Patel, of VLS Pharmacy in and New Drug Loft in New York City,as its 2020 M. George Webber, PhD, Compounding Pharmacist of the Year.

More than 1,300 compounders from the U.S., Canada, Australia and beyond attended the companys virtual International Seminar 2020 on November 6 where PCCA President Jim Smith announced Patels award.

Smith had presented the award to Patel on October 26, on a Zoom call where Patels family and pharmacy staff also joined him to celebrate the honor.

Thank you for this honor. Im truly humbled by it, Patel I quoted saying in a press release. I always want to serve anyone who has a problem or a difficult time. I like to help them. Thats how my family grew up, thats what Im following, and I tell my daughters to do the same. I like teaching and sharing with others, so that we can save lives. My reward has always been helping people feel better, he added.

The award is presented annually to an independent pharmacist who has demonstrated service excellence to patients, health care providers and pharmacy colleagues, according to the press release. The award is named after the late M. George Webber, PhD who was a longtime professor with the University of Houston College of Pharmacy and was instrumental in founing PCCA in 1981.

What an honor it is to have someone of Gopeshs caliber and character blessing the lives of patients in his community and blessing those in the PCCA community, Smith is quoted saying in the release. In 2020, his care and compassion especially stood out through his work with patients afflicted with COVID-19 and their physicians, and his commitment to protect the members of his community with hand sanitizer donations and much more. Were all enriched because of our knowledge of him and our friendship with him.

According to his bio on New Drug Lofts website, Patel is a PCCA member since 2009, and is the compounding pharmacist-in-charge and owner at VLS Pharmacy and New Drug Loft. A 1979 graduate of MS University in Baroda, India, Patel has extensive clinical knowledge in hormone replacement therapy, dermatology, urology and IV therapy.

Patel is also a member of the Pharmacists Society of the State of New York, Alliance for Pharmacy Compounding, American Academy of Anti-Aging Medicine and American College for Advancement in Medicine.

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Brooklyn-based pharmacist named Compounding Pharmacist of the Year - newsindiatimes.com

A new study led by the University of Edinburgh and Queen Mary University of London has identified a protein that plays a crucial role in protecting the bodys blood stem cells from damage during infection, a finding that could lead to new ways to slow down the aging process.

Hematopoietic stem cells (HSCs) are found in bone marrow, and from there they produce other blood and immune cells. When an infection strikes the body, HSCs are known to ramp up production to fight it off but thats raised some questions for scientists in the past. In particular, how do they protect themselves from damage while working overtime?

We know that inflammatory pathways induced by infection force blood stem cells to rapidly produce immune cells to help combat infections, says Kamil Kranc, corresponding author of the study. However, these pathways can eventually exhaust stem cells or cause their premature aging, and it is important to understand how this can be stopped.

In the new study, the researchers identified a protein called YTHDF2 that seems to be responsible for this important job. When an infection arises, the HSCs produce far more immune cells, but at the same time that triggers inflammatory processes that can damage the stem cells. The study found that the YTHDF2 protein regulates genes that control those inflammatory processes, protecting the stem cells from premature aging.

To investigate the role of YTHDF2, the team engineered mice to be deficient in the protein, then administered a chemical that acts like a viral infection. Sure enough, the mices HSCs appeared to suffer chronic inflammation, altering the production of different blood cell types. Interestingly, the blood of these young animals began to resemble that of much older mice.

The new study seems to agree with previous reports that blood transfusions from young animals to older ones can improve the health of the recipient, and even slow the progression of diseases like Alzheimer's. As such, the team says that future work could investigate whether manipulating levels of YTHDF2 may be a potential anti-aging treatment.

The research was published in the Journal of Experimental Medicine.

Source: University of Edinburgh

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Protective protein could help keep blood young and healthy - New Atlas

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Anti-Aging medicine has come a long way. From the first A4M conference in Vegas in 1994 to the new phase of regenerative medicine that we are entering, it has been a wild ride.

In the past, most of anti-aging medicine was based on balancing your hormones so that you could feel like youryounger self from 5 or 10 years ago.

Now with the second phase of anti-aging medicine which includes a host of regenerative practices we can actually turn back the body into a much younger version of yourself (15 or 20 years even).

Listen to the lively interview with one of the original anti-aging doctors who has been extensively in this field for 25 years Dr. Philip Lee Miller.

First of all, Dr. Miller shares how we works with his patients tohelp themachieve their goals. He checks and reviews hormones such as Estrogen, Progesterone, Testosterone, Thyroid, Adrenals and may more.

Next we discuss the near future of anti-aging medicine and what developments he sees on the near horizon. Dr. Miller touches on Senolytics for Senescent cells, Telomere extension drugs, winning the war over cancer, and tumor suppressors.

Dr. Miller shares some of his anti-aging hacks, which are overlooked by most of us.

We also discuss his unique anti-aging hacks that we can use to look and feel younger while we live longer and healthier.

Links to Dr. Millers websites:

Website:https://www.antiaging.com

Blog:http://blog.antiaging.com

Linkedin:https://www.linkedin.com/in/philipleemillermd/

Flicker account:https://www.flickr.com/photos/philipleemiller

Visit us on instagram at @antiaginghacks and on facebook at facebook.com/antiaginghacks.

If you liked the podcast so far, please leave us a review and/or a rating. It helps the show get discovered by more people who could benefit from this information.

If you have ideas that you would like us to cover in the future, please email us at info@antiaginghacks.net.

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Anti-Aging Medicine: Now and the Near Future | antiaginghacks