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Category Archives: Anti-Aging Medicine
Two Pitt Faculty Members Inducted into National Academy of Medicine for Work on Aging and Neuro-Rehab – Newswise
Newswise PITTSBURGH, Oct. 19, 2020 Two physician-scientists at the University of Pittsburgh School of Medicine have been elected to the prestigious National Academy of Medicine.
Among the class of 100 new inductees honored at todays annual meeting are Toren Finkel, M.D., Ph.D., professor of cardiology and director of the Pitt Aging Institute, and Amy Wagner, M.D., professor of physical medicine and rehabilitation and neuroscience at Pitt.
This is a wonderful honor from my peers, made possible through my good fortune of working with so my talented people along the way, as well as the unwavering support of my family, Finkel said.
Finkels work centers on how oxidative stress and the function of mitochondria alter the rate of aging. The long-term goal is to uncover the molecular basis of aging and age-related diseases through the study of a variety of different cellular pathways. Recently, Finkels focus has been on autophagythe bodys natural way of clearing out old and damaged parts of cellsas a target for anti-aging therapeutics.
Wagner uses biomarkers and statistical modeling to predict how well patients will recover from brain injury and to guide clinical decisions along the waya strategy she calls personalized rehabilitation medicine. This clinical research informs her studies using in vivo pre-clinical models aimed at identifying intervention strategies that promote neurorecovery. She also treats patients with neurological conditions who are undergoing inpatient rehabilitation, and she is a consultant for neurologically devastated patients during their acute hospitalization at UPMC.
One of the things that I look forward to the most with my Academy membership is being able to use my voice to represent and serve all rehabilitation populations, but particularly our brain injury population, which is underserved, Wagner said. Disability is such a huge issuethere are over 50 million people in this country who have some type of disability. Being able to advocate for them and to bring that to a national stage showing what we have to offer is really important.
Election to the Academy is considered one of the highest honors in the fields of health and medicine and recognizes individuals who have demonstrated outstanding professional achievement and commitment to service. New members are elected by current members through a process that recognizes individuals who have made major contributions to the advancement of medical sciences, health care and public health.
This distinguished and diverse class of new members is a truly exceptional group of scholars and leaders whose expertise in science, medicine, health and policy will be integral to helping the National Academy of Medicine address todays most pressing health challenges and inform the future of health and health care for the benefit of everyone around the globe, said Academy President Victor J. Dzau, M.D.
It is excitingbut hardly surprisingto see Drs. Finkel and Wagner recognized for their remarkable contributions to the field of medicine, said Pitt Senior Vice Chancellor for the Health Sciences Anantha Shekhar, M.D., Ph.D. On behalf of all of their many proud colleagues and students at the University of Pittsburgh: Congratulations!
To read this release online or share it, visit https://www.upmc.com/media/news/101920-finkel-wagner-nam.
Franz Skincare USA Announces Second Consecutive Win of "Top Skincare Face Mask" in the 2020 Aesthetic Everything Aesthetic and Cosmetic…
Franz Skincare USA is the next step in beauty tech. From pioneering the world's first Trans Dermal Drug Delivery System in the form of our groundbreaking TissueX Technology, to bringing microcurrent treatments home, Franz Skincare USA strives to bring the most innovative treatments to your home. Inspired by the ocean's waves, Tissue X microcurrent technology harnesses the power of water to naturally create tiny, rejuvenating waves across your face. Your at-home facelift, this innovative process will leave your skin feeling tightened, toned, and instantly hydrated. This is because Tissue X delivers healing ingredients 6x deeper than topical application. No downtime or needles needed!
Originally developed for spa use, Saint 21 is the most powerful mask in our lineup. The gold coating boosts the natural ion power to get better adhesion to your skin, resulting in more than a 50% increase in ingredient delivery. Ideal for advanced anti-aging, included are four deluxe packages formulated for the delicate skin around the eyes and mouth.
With all of our products, we're continuing Franz's tradition of bringing easy, high-tech solutions to your home. To enhance your anti-aging routine, apply our new Stem Cell Culture Medium Ampoule under the Saint 21 Microcurrent Dual Facial Mask. Made with a groundbreaking 10% concentration of Human-derived stem cell culture, this ampoule heals skin at the cellular level by stimulating cell growth and differentiation and activating collagen & elastin synthesis. This serum will reconstruct skin back to its healthiest state for a younger, firmer, and flawless complexion. This dynamic duo heals skin from within.
Savannah Engel Public Relations [emailprotected]https://franzskincare.com@franzskincareusa
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Aesthetic Everythinghosts theBeauty Expo Trade Show & Celebrity/Media Red Carpet Awards. Aesthetic Everything 2021 Beauty Expoand awards will be June 12th, 2021.
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Dr. Kathryn Alcarez Joins The Exclusive Haute Beauty Network Representing The Medspa Category – PR Web
Dr. Kathryn Alcarez is the founder and Medical Director of Aesthete Medical Wellness and Medspa.
NEW YORK (PRWEB) October 22, 2020
Dr. Kathryn Alcarez is a Manhattan-based, Internal Medicine Physician and has a combined 14 years of experience and specialized training in Aesthetic Medicine, Obesity Medicine, and Preventative Medicine. She is the founder and Medical Director of Aesthete Medical Wellness and Medspa.
Dr. Alcarez received her medical degree at the University of New England College of Osteopathic Medicine in Maine and completed her residency in Internal Medicine at Lenox Hill Hospital. She is affiliated with Mount Sinai Beth Israel and NYU Langone Medical Center.
Using a holistic and evidence-based approach to medicine, Dr. Alcarez seeks to ensure that her patients receive the best medical care to maintain long-term health and wellness. She considers physical, mental, and aesthetic health as integral to patients overall wellbeing. For this reason, Dr. Alcarez offers comprehensive aesthetic consultations that include botox for medical purposes like migraines and hyperhidrosis, botox and fillers for anti-aging, radiofrequency skin tightening (Inmode Optimas), and radiofrequency body contouring (Inmode Contoura and Cuteras Trusculpt ID offered at the downtown location).
Learn more about Dr. Kathryn Alcarez by visiting: https://hauteliving.com/hautebeauty/member/dr-kathryn-alcarez/
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How to assess your senior horses quality of life and know when its time to let go
Owning senior horses is a blessing and a curse. Youve enjoyed many years of partnership, built a strong bond, and share a mutual trust. On the other hand, you have to manage things like aging joints and worn-out teeth. Theres also that one pretty significant curse: Horses dont live forever, and every owner knows he or she will eventually have to say that final goodbye.
Sometimes the horse makes the choice for us, going on his own, without prolonged suffering. Other times its a decision were forced to makea severe colic or an irreparable injury that necessitates euthanasia. But in many cases owners must make decisions that arent black and white. When is it right to keep going, managing a few age-related health issues, and when is the most humane option to end his chronic pain and suffering?
We asked two veterinarians how owners can monitor their aging equids welfare and make end-of-life decisions.
Quality of life is a complex and sometimes difficult-to-evaluate concept.
For a good quality of life, horses should have adequate shelter, food, water, be treated with kindness, and be free of pain and disease, says Janice E. Kritchevsky, VMD, MS, a professor of large animal internal medicine at the Purdue University College of Veterinary Medicine, in West Lafayette, Indiana. Because horses are herd animals, they should have companionship. A horse all by itself could probably check most of the welfare boxes, but Im not sure you could ever say a single herd animal is happy.
Liz Arbittier, VMD, an assistant professor of clinical equine field service at the University of Pennsylvania School of Veterinary Medicines New Bolton Center, in Kennett Square, cites the American Association of Equine Practitioners guidelines to help determine whether a horse still has a decent quality of life. A horse should not have to:
However, look at the last point, and then think about all of the horses out there that happily live on a gram of Bute (the non-steroidal anti-inflammatory drug [NSAID] phenylbutazone) for years with no adverse effects, she says. While they certainly can have problems related to chronic NSAID use (e.g., gastric ulcers, kidney issues)and this step should not be taken without consulting your veterinarianso many horses live comfortable and happy lives with some medical assistance. If the horse requires an excessive dose of NSAIDs to live a comfortable retired life, that may be a different story.
Like everything with horses, it comes down to each situation, which is why its important to work with a team to ensure seniors remain healthy as they age.
On the most basic level, Kritchevsky says, a horse with a good quality of life should interact with the owner, other people, and horses. They should move out, at least at a walk, willingly and have a good appetite. Finally, they should not have a chronic disease condition such as equine asthma, lameness, or (gastrointestinal) upset that cannot be managed. If these are present, one can assume that the quality of life is diminished.
Old age isnt a disease, Kritchevsky says. Horses, like people, are very individual, and some horses are old at 17 while others are young at 27.
So age alone doesnt diminish a horses quality of life. Heres more on the various disease processes that do. Thisarticle continues in the October 2020 issue ofThe Horse: Your Guide to Equine Health Care. Subscribe now and get an immediate download of the issue to continue reading. Current magazine subscribers can access the digital edition here.
Senior Horses and Living the Good Life The Horse - TheHorse.com
Choosing a new beauty product is like making a new friend. It may take some trial and error to find the one that makes you feel your best. To bypass that getting-to-know-you period, allow us to introduce you to products that will never let you down. We turned to our panel of top doctors and industry pros for skincare that works, holy grail hair finds, makeup must-haves, and more.
Foaming Facial Cleanser
Its so important to wash your face twice daily, especially at night. This one gently cleanses with ceramides, hyaluronic acid, and niacinamide to avoid stripping or overdrying the skin. Dr. Marchbein
BEST DAY CREAM
Rich Revitalizing Nourishing Cream
Im in my 40s, and I like my skin to be glowy, but I dont want to walk around all day looking shiny. This one is particularly thick and nourishing, really drives in hydration, and is good for everybodys skin. Dr. Gohara
BEST FACE SUNSCREEN
Eryfotona Actinica SPF 50+
This sunscreen is belovedby both women and men, as it rubs in beautifully without leaving a white film. And its a physical sunscreen, so its great for those with sensitive skin. Dr. Marchbein
PRO TIP: SPF should be put on the face, ears, neck, and hands every morning and reapplied every two hours when youre exposed to the suneven if youre just sitting near a window!
BEST ACNE SPOT TREATMENT
Effaclar Duo Acne Spot Treatment
It has 5.5% benzoylperoxide, which kills acne-causing bacteria. As aspot treatment, salicylic acid (an exfoliant) wont work as well overnight as this does.Dr. Woolery-Lloyd
BEST NIGHT CREAM
Natural Moisturizing Factors + HA
Im a big fan because itsso affordable. It does a nice job of incorporating basic ingredients like hyaluronic acid in a cosmetically elegant formulation that isnt too heavy. I put it on after myretinoidat night.Dr. Gohara
BEST LIP TREATMENT
Barrier+ Lip Repair Balm
This is a great everydayrepair balm. It works wellfor chapped lips and hasthat hydrating, soothingaction because it containsprotective petrolatum aswell as coconut and jojobaoils.Dr. Woolery-Lloyd
PRO TIP: Dab on your spot treatment where you need it before putting on moisturizer (ideally at night) so it really has a chance to penetrate the skin and work its zit-zapping magic.
PHOTOS: Jeffrey Westbrook / STYLING: MIA KATOH
BEST WRINKLE TREATMENT
Intensive Age Refining Treatment 0.5% Pure Retinol
When it comes to retinol,I dont compromise. I like to have the science (knowing its been tested to build collagen), the right percentage (at least 0.5%), and the ability to use it regularly without irritation. When I find a product that has all those things, I stick with it. Dr. Gohara
BEST EYE CREAM
Total Eye 3-in-1 Renewal Therapy SPF 35
I like multitaskingproducts, and this is three things: Its a concealer and a sunscreen, and it has anti-aging properties. Eyes age quickly, so when it is used as a concealer, youre getting ample SPF in that area. Dr. Gohara
BEST BRIGHTENING SERUM
Phloretin is my favoritevitamin Cantioxidant serum to help protect against and repair free radical damage. It can help reduce brown spots, evens skin tone, and protects from further sun damage. Dr. Marchbein
PRO TIP: Apply retinol at night before bed. Put a pea-size amount on your finger and divide it equally among the four quadrants of your face. Follow with moisturizer to minimize redness and peeling.
PHOTOS: JEFFREY WESTBROOK / STYLING: MIA KATOH
BEST BODY CLEANSER
Soothing Skin Body Wash (Almond)
I love this cleanser.Its mild, with plant-rich surfactants (compounds that help clean the skin). The almond scent is amazing in the shower, and my skin feels so soft after using it. Morse
BEST BODY SCRUB
Exfoliating Body Polish
Dove Body Polish is myfavorite (and the one I have in my own shower), as it has a very small particle size, which is less abrasive on the skin. It contains glycerin, shea butter, and other hydrating ingredients to help gently remove dead skin cells. Dr. Marchbein
BEST HAND CREAM
Advanced Repair Hand Cream
This has glycerin, whichgives the product a slick feel without its being sticky or heavy. It gives you instant relief if you have ultra dry hands, so I recommend keeping it in your bag and applying as needed. Dr. Woolery-Lloyd
BEST BODY MOISTURIZER
Ultra Repair Cream
I like products withingredients that naturallyexist in the skin, like thehydrating ceramides in thiscream. Im also a fan ofthe oatmeal, which quellsirritation.Dr. Gohara
PHOTOS: JEFFREY WESTBROOK / STYLING: MIA KATOH
Make Me Blush Velvet Blush
Instead of a super-pigmented blush, I love a buildable formula because its easier to control. This powder blush has the color payoff but looks really soft on the cheeks. Quynh
BEST LIP COLOR
Tinted Daily Lip Balm
This is like a love child of alipstick and a lip balm. The color is beautiful and lasts for hours, and it is truly moisturizing. Morse
BEST BROW PRODUCT
Tinted Brow Butter
It has just enough colorto fill in bald spots andprovides just enough holdto tame flyaways. The littlespoolie brush perfectlyfeathers brows into place.Morse
PRO TIP: For brows that look natural, focus more of the product on the outer edges. Packing too much on the inner areas toward your nose often results in a blocky look, Quynh says. If you mess up or apply too much, use a clean spoolie to brush out any clumps.
Luminous Silk Concealer
Not only will it cover upblemishes, but it wont accentuate the dryness of spots. It has a nice radiant, natural finish.Quynh
Skin Twin Featherweight Foundation
I love that its reallyhydrating because it has hyaluronic acid. It comes in many shades so you can truly find your matchand it feels as if youre wearing nothing.Quynh
Voluminous Original Mascara
This old-school formula is so thick and makes your lashes look so full. If you want to avoid any smudging throughout the day, go forthe waterproof version.Quynh
PRO TIP: Dot the concealer where you need it and use a bare brush to buff gently. For a seamless finish, start with less product and slowly add more in thin layers.
PHOTOS: JEFFREY WESTBROOK / STYLING: MIA KATOH
Pure Shampoo Hair Bathe
Its important for a shampoo to provide both vital nutrients and the ability to gently remove product buildup. This does exactly that as it recharges the follicle with nourishing ingredients and cleanseswithout drying outthe hair.Reslan
Humectress Ultimate Moisture Conditioner
Humectress has alwaysbeen a staple for me. It adds a lot of moisture, rinses out well, works great on normal-to-dry hair, and is one of those tried-and-true products that has spanned generations.Hardges
Wild Marula Tangle Spray
The ideal detangler does thejob without building up on hair, which can cause dullness over time. This is a unique leave-in that uses marula oil, best known for its lightweight moisturizing effects and being easy to wash out.Reslan
PRO TIP: Spray this detangler onto your hair to air-dry or before using any thermal tool, as it also provides protection.
BEST HAIR TREATMENT
This is made withskin-soothing green tea extract and silk amino acids to smooth and repair your hair while nourishing your scalp. Its lightweight too.Reslan
BEST SCALP TREATMENT
Serene Scalp Exfoliating Scrub
A healthy scalp is goingto breed healthy hair. This duo is like an exfoliator and toner for the scalp. It helps moisturize, remove buildup, and bring the pH back where it needs to be. Hardges
BEST SCALP TREATMENT
Serene Scalp Soothing Leave-on Treatment
A One Health approach, requiring the collaboration of human, animal, and environmental health partners, is key to preventing Leishmania cases in Canada and the US
Leishmania is a flesh-eating parasite that affects millions of people each year, in 98 countries and territories but isnt native to Canada and the United States. So why are veterinarians starting to report Leishmania here, so far from this parasites natural warm climate?
Leishmania are microscopic parasites transmitted by sandfly bites, and cause a disease called leishmaniosis. There are several forms of this disease, affecting the skin, mucous membranes and internal organs. Some forms of the disease lead to severe disfigurement, others death.
Leishmaniosis is classified as a neglected tropical disease by the World Health Organization, primarily affecting those in tropical and subtropical regions. The disease particularly affects populations lacking access to adequate housing and sanitation services.
Leishmaniosis is a zoonotic disease, meaning it can be transmitted from animals to humans; dogs are the reservoir for this parasite.
Recently, veterinarians in the US and Canada have been detecting Leishmania in imported dogs: the disease has been detected in dogs in 18 states and two provinces.
Our laboratory received reports of at least 10 in Qubec within the span of a year. Soon after, we were presented with a case ourselves: a dog imported with suspected fight wounds later diagnosed to be Leishmania.
More and more, owners are travelling with their pets or importing animals from other countries. The regulations for bringing pets into Canada are lax generally, the only requirements are proof of rabies vaccination and a certificate from a veterinarian declaring the animal to be in apparent good health.
Furthermore, since many of the tests and diagnostic treatments for exotic diseases (including leishmaniosis) are unfamiliar or inaccessible in Canada, diagnosis and treatment are complicated.
This puts the health of the patient and ultimately the public, at risk.
Although the exact species of sandflies that transmit Leishmania are not present in Canada, reports of Leishmania maintaining itself within groups of kennelled foxhounds in 18 states and two provinces strongly suggest that the parasite can be transmitted from dog to dog: through bites, breeding or blood transfusions. In addition, it has recently been demonstrated that ticks can also transmit leishmaniosis.
Therefore, although unfortunate, Leishmania establishment in Canada and the US remains possible.
Treatment of leishmaniosis is currently limited to very few drugs, most of which have been in use for decades. In recent years, there has been an increase in Leishmania drug resistance and treatment failure.
Scientists, including us, are searching for clues to better understand how these parasites survive in the presence of anti-leishmanial drugs. A number of experiments have led us (and others) to focus on Leishmanias release of extracellular vesicles.
Extracellular vesicles are small, round particles with a fatty outer membrane, and they are produced by all living cells, including Leishmania parasites. Although tiny you need an electron microscope to see them these particles transport valuable cargo that ranges from DNA to fats and proteins. The contents of these vesicles provide a snapshot of their cell of origin, and can be delivered to nearby cells.
Recent studies have found that not only do the size and shape of these vesicles differ between sensitive and drug-resistant strains of Leishmania, but vesicles produced by drug-resistant parasites contain special drug-resistance molecules.
A better understanding of extracellular vesicles function is another step towards understanding how drug resistance spreads among Leishmania populations with the goal of preventing it.
Additionally, research has demonstrated that when an infected sandfly bites a human, its not just parasites that are injected into the bloodstream: extracellular vesicles come along too and are confronted by our immune system.
Studying extracellular vesicles may provide vital information for the development of new Leishmania therapies or a vaccine.
Mandatory reporting of canine leishmaniosis cases by veterinarians, easy access to fast and reliable diagnostic tests and appropriate treatments and an overhaul of animal importation regulations are critical.
A One Health approach, requiring the collaboration of human, animal, and environmental health partners, is key to preventing Leishmania cases in Canada and the US.
Victoria Wagner, Veterinarian, M.Sc. student in Molecular Parasitology, Universit de Montral; Christopher Fernandez-Prada, Assistant professor at Universit de Montral (Faculty of Veterinary Sciences); Head of the animal parasitology diagnostic laboratory of UdeM; Adjunct professor McGill University (Faculty of Medicine), Universit de Montral, and Martin Olivier, Full Professor at McGill University, Departments of Medicine, Microbiology and Immunology; Senior Investigator at the Research Institute of the McGill University Health Centre and Chair of the Laboratory for the Study of Host-Parasite Interaction.
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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A flesh-eating parasite carried by dogs is making its way to North America - Down To Earth Magazine